scholarly journals A Case of an Insufficiency Fracture of the Medial Proximal Tibia Secondary to Osteomalacia Associated with Long-Term Saccharated Ferric Oxide Administration

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Daichi Ishimaru ◽  
Hiroshi Sumi
Keyword(s):  
Ferric Oxide ◽  
Proximal Tibia ◽  
Insufficiency Fracture ◽  
Varus Deformity ◽  
Term Administration ◽  
Hypophosphatemic Osteomalacia ◽  
Fragile Fracture ◽  
Iron Deficit

This article presents a case of insufficiency fracture of medial proximal tibia caused by long-term administration of saccharated ferric oxide (SFO) in a 77-year-old female. In this case, 2-year administration of SFO for iron deficit anemia induced hypophosphatemic osteomalacia and finally resulted in an insufficiency fracture of medial proximal tibia. Hypophosphatemia and pain due to the insufficiency fracture were recovered promptly by withdrawing SFO administration and rest. This case represented varus deformity of the knee associated with osteoarthritis, which may also cause the insufficiency fracture of medial proximal tibia in addition to osteomalacia due to long-term administration of SFO. Long-term SFO administration should be avoided because of a definitive risk of osteomalacia and fragile fracture.

scholarly journals A Case of FGF23-related Hypophosphatemic Osteomalacia Caused by Long-term Administration of Saccharated Ferric Oxide.

2011 ◽  
Vol 100 (10) ◽  
pp. 3031-3033
Author(s):  
Yumie Wada ◽  
Yuka Kinoshita ◽  
Manabu Taguchi ◽  
Seiji Fukumoto ◽  
Toshiro Fujita
Keyword(s):  
Ferric Oxide ◽  
Term Administration ◽  
Hypophosphatemic Osteomalacia

Forty-Year Experience in Application of Correction Osteotomies for Blount Disease Treatment

2012 ◽  
Vol 19 (3) ◽  
pp. 3-8
Author(s):  
N. A Tenilin ◽  
A. B Bogos'ayn ◽  
D. S Karataeva
Keyword(s):  
Proximal Tibia ◽  
Surgical Intervention ◽  
Deformity Correction ◽  
Varus Deformity ◽  
Long Term Results ◽  
Disease Treatment ◽  
Correction Osteotomy ◽  
Different Types ◽  
Blount Disease

Long-term results (up to 40 years) of surgical treatment using different types of correction osteotomy in 51 children with Blount disease showed that the operation was necessary but a delayed measure. The authors showed that when deformity achieved the degrees requiring surgical intervention with bone transaction the deforming gonarthrosis inevitably developed at terms up to 10 years after operation. The main causes of varus deformity recurrence were determined, i.e. presence of active but disturbed growth and ossification processes, distal osteotomy level, absence of intraoperative hypercorrection, inobservance of postoperative orthopedic regimen. The only way to achieve good results is early operative intervention directed to growth normalization and formation of proximal tibia with spontaneous deformity correction during the period of child's growth.

The efficacy and safety of long-term administration of alpha-interferon and lamivudine in patients with chronic hepatitits B

2001 ◽  
Vol 120 (5) ◽  
pp. A572-A572
Author(s):  
F JABOLI ◽  
E RODA ◽  
C FABBRI ◽  
S MARCHETTO ◽  
F FERRARA ◽  
...  
Keyword(s):  
Alpha Interferon ◽  
Efficacy And Safety ◽  
Term Administration

STUDIES IN THE SUPPOSED GOITROGENOUS EFFECT OF TAP WATER IN HELSINKI

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 630-636
Author(s):  
F.-E. Krusius ◽  
P. Peltola
Keyword(s):  
Tap Water ◽  
Physiological Saline ◽  
Normal Weight ◽  
The Body ◽  
Iodine Uptake ◽  
Redistilled Water ◽  
Detectable Difference ◽  
Term Administration ◽  
Long Term Experiment

ABSTRACT The study reported here was performed in order to examine the tap water of Helsinki for its alleged goitrogenous effect. In a short-term, 24-hour experiment with rats, kept on an iodine-poor diet, we noticed no inhibition of the 4-hour 131I uptake, as compared with that of animals receiving physiological saline instead of tap water. Two similar groups of rats receiving 1 and 2 mg of mercazole in redistilled water showed a distinct blockage of the 4-hour uptake, which proved the effect of this substance. In a long-term experiment of 5 weeks' duration there was no detectable difference in the body weight, thyroid weight and the 4-hour 131I uptake when the rats receiving tap water or distilled water to which 0.45 per cent of sodium chloride was added were compared with each other. Replacement of tap water by a 10 mg per cent solution of mercazole in redistilled water enlarged the thyroid to double its normal weight and increased the 131I uptake to approximately five times that of the controls. Thus our experiments failed to demonstrate any goitrogenous effect in the tap water of Helsinki. Changes similar to those produced by a long-term administration of mercazole, i. e. an enlargement of the thyroid and an increased thyroidal iodine uptake, have been shown to be due to milk collected from goitrous areas. The observations here reported confirm the importance of milk in the genesis of the goitre endemia of Helsinki. Attention is further called to the fact that a thyroidal enlargement combined with an increased thyroidal iodine uptake cannot always be taken as a sign of iodine deficiency because similar changes may be produced by the administration of goitrogens.

EFFECTIVENESS OF ANTIAGGREGANT THERAPY ON KIDNEY ACTIVITY IN THE PREDIALYSIS STAGE OF CHRONIC KIDNEY DISEASE

2020 ◽  
Vol 6 (1) ◽  
pp. 55-60
Author(s):  
Khabib Barnoev ◽  
◽  
Sherali Toshpulatov ◽  
Nozima Babajanova ◽  
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Comparative Study ◽  
Functional Status ◽  
Stage Ii ◽  
Term Administration ◽  
Antiaggregant Therapy

The article presents the results of a study to evaluate the effectiveness of antiaggregant therapy on the functional status of the kidneys in 115 patients with stage II and III chronic kidney disease on the basis of a comparative study of dipyridamole and allthrombosepin. Studies have shown that long-term administration of allthrombosepin to patients has led to improved renal function.

Sign in / Sign up

Export Citation Format

Share Document