scholarly journals Magnesium Oxide Nanoparticles Reinforced Electrospun Alginate-Based Nanofibrous Scaffolds with Improved Physical Properties

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
R. T. De Silva ◽  
M. M. M. G. P. G. Mantilaka ◽  
K. L. Goh ◽  
S. P. Ratnayake ◽  
G. A. J. Amaratunga ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Tensile Strength ◽  
Elastic Modulus ◽  
Polyelectrolyte Complex ◽  
Mechanical Stability ◽  
Poly Vinyl Alcohol ◽  
Sem Images ◽  
Mgo Nanoparticles ◽  
Nanofibrous Scaffolds ◽  
Electrospinning Method

Mechanically robust alginate-based nanofibrous scaffolds were successfully fabricated by electrospinning method to mimic the natural extracellular matrix structure which benefits development and regeneration of tissues. Alginate-based nanofibres were electrospun from an alginate/poly(vinyl alcohol) (PVA) polyelectrolyte complex. SEM images revealed the spinnability of the complex composite nanofibrous scaffolds, showing randomly oriented, ultrafine, and virtually defects-free alginate-based/MgO nanofibrous scaffolds. Here, it is shown that an alginate/PVA complex scaffold, blended with near-spherical MgO nanoparticles (⌀ 45 nm) at a predetermined concentration (10% (w/w)), is electrospinnable to produce a complex composite nanofibrous scaffold with enhanced mechanical stability. For the comparison purpose, chemically cross-linked electrospun alginate-based scaffolds were also fabricated. Tensile test to rupture revealed the significant differences in the tensile strength and elastic modulus among the alginate scaffolds, alginate/MgO scaffolds, and cross-linked alginate scaffolds (P<0.05). In contrast to cross-linked alginate scaffolds, alginate/MgO scaffolds yielded the highest tensile strength and elastic modulus while preserving the interfibre porosity of the scaffolds. According to the thermogravimetric analysis, MgO reinforced alginate nanofibrous scaffolds exhibited improved thermal stability. These novel alginate-based/MgO scaffolds are economical and versatile and may be further optimised for use as extracellular matrix substitutes for repair and regeneration of tissues.

Design and Preparation of an Electrospun Biomaterial Surgical Patch

2009 ◽  
Vol 24 (1_suppl) ◽  
pp. 158-168 ◽  
Author(s):  
Hai Lu ◽  
Wei-Jun Chen ◽  
Yan Xing ◽  
Da-Jun Ying ◽  
Bo Jiang
Keyword(s):  
Tensile Strength ◽  
Elastic Modulus ◽  
Yield Strength ◽  
Collagen Type ◽  
Sem Images ◽  
Significant Potential ◽  
Clinical Transplantation ◽  
Porcine Pericardium ◽  
Porous Morphology

A biomaterial patch of electrospun collagen type fibers was designed and produced by electrospinning seven different concentrations (8%-20% w/v) of collagen solutions. The tensile strength, yield strength, and elastic modulus of the electrospun collagen fibrous patches were found to be suitable for clinical transplantation. No significant differences versus fresh porcine pericardium as controls were observed. The SEM images of the groups showed that the patches were smooth with uniform interwoven and porous morphology. The fibrous patches were biocompatible and did not elicit local or systemic toxic effects when implanted in vivo. These electrospun collagen fibrous patches have significant potential as surgical biomaterial patches.

Preparation and Characterization of Poly(Vinyl Alcohol)(PVA)/Hydroxyapatite (HA) Nanofibrous Scaffolds

2011 ◽  
Vol 284-286 ◽  
pp. 459-463 ◽  
Author(s):  
Yuan Yuan Qi ◽  
Bin Liu ◽  
Xing Bin Yan
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Tensile Strength ◽  
Drug Delivery Systems ◽  
Poly Vinyl Alcohol ◽  
Elongation At Break ◽  
Nanofibrous Scaffolds ◽  
Potential Applications

Nanofibrous scaffolds of PVA and HA were prepared by electrospinning. SEM showed the scaffolds had porous nanofibrous morphology, and the diameter of the fibers was in the range of 200-1000 nm. FTIR and XRD showed the presence of HA in the scaffolds. The mechanical properties of the scaffolds changed by the adding content of HA. For the nanoscaffolds with 2wt % HA, the ultimate tensile strength and the elongation at break was 7.5 MPa and 17%. The PVA/HA nanoscaffolds prepared by electrospinning indicated good properties, and had a potential applications in bone tissue engineering and drug delivery systems.

scholarly journals Fabrication and Characterization of Electrospun Wool Keratin/Poly(vinyl alcohol) Blend Nanofibers

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Shuai Li ◽  
Xu-Hong Yang
Keyword(s):  
Tensile Test ◽  
Vinyl Alcohol ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
Gravimetric Analysis ◽  
X Ray Diffraction ◽  
Sem Images ◽  
Electrospinning Method ◽  
Wool Keratin

Wool keratin/poly(vinyl alcohol) (PVA) blend nanofibers were fabricated using the electrospinning method in formic acid solutions with different weight ratios of keratin to PVA. The resultant blend nanofibers were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR), X-ray diffraction (XRD), thermal gravimetric analysis (TGA), and tensile test. SEM images showed that the diameter of the blend nanofibers was affected by the content of keratin in blend solution. FTIR and XRD analyses data demonstrated that there were good interactions between keratin and PVA in the blended nanofibers caused by possibly hydrogen bonds. The TGA study revealed that the thermal stability of the blend nanofibers was between those of keratin and PVA. Tensile test indicated that the addition of PVA was able to improve the mechanical properties of the electrospun nanofibers.

Optically Transparent Nanocomposite Based on Cellulose Nanofibers from Newspapers and Polyurethane

2012 ◽  
Vol 174-177 ◽  
pp. 905-911 ◽  
Author(s):  
Xue Ting Li ◽  
Da Gang Li ◽  
Li Xu ◽  
Yu Mei Wang ◽  
Dong Liang Lin
Keyword(s):  
Tensile Strength ◽  
Elastic Modulus ◽  
Cellulose Nanofibers ◽  
Three Dimensional ◽  
High Strength ◽  
Wood Powder ◽  
Sem Images ◽  
High Transparency ◽  
Dimensional Network ◽  
Optically Transparent

The goal of this paper was to develop an optically transparent nanocomposite with high strength by reinforcing polyurethane (PU) with cellulose nanofibers (CNFs) extracted from newspapers. The FE-SEM images show that through chemical and mechanical treatments, newspaper CNFs with diameters ranged from 20 to 100 nm and an aspect ratio of over 1000 were successfully obtained as well as wood powder. They were cross-linked together and formed a special three-dimensional network structure. The nanocomposite was fabricated by impregnating the CNF sheet into transparent PU resin and cured under ultraviolet. Results demonstrate that the transparency of newspaper CNF/PU nanocomposite was as high as wood CNF/PU nanocomposite. The elastic modulus and tensile strength of newspaper CNF/PU composite were increased roughly eighteen times and two times respectively while retaining the high transparency of PU, which was nearly the same with wood CNF/PU composite.

Fabrication and Characterization of Poly(vinyl Alcohol)/Functionalized Graphene Oxide Nanofibers Produced by Electrospinning Method

2013 ◽  
Vol 747 ◽  
pp. 405-408
Author(s):  
Yuan Hsiang Yu ◽  
Chih Jie Jan
Keyword(s):  
Electron Microscopy ◽  
Graphene Oxide ◽  
Photoelectron Spectroscopy ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Functionalized Graphene ◽  
Sem Images ◽  
Functionalized Graphene Oxide ◽  
X Ray ◽  
Electrospinning Method

A series of poly (vinyl alcohol) (PVA)/functionalized graphene oxide (FGO) nanofibers with low feeding ratios of FGO to PVA were fabricated by electrospinning method. In this study, the prepared PVA/FGO nanocomposites were dispersed in water phase followed by electrospinning treatment under different operational parameters (i.e., applied voltage, feeding rate and FGO contents) to give nanofibers of various diameters and morphologies. The morphology, diameter and structure of electrospun nanofibers and FGO were investigated by Fourier transform infrared (FT-IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), (TGA) and differential scanning calorimetry (DSC). SEM images showed that the morphologies of the nanofibers were improved by the incorporation of FGO at a low loading content (e.g., 0.1~0.5 wt %) as compared to pure electrospun PVA. The crystallinity and thermal stability of PVA/FGO nanofibers were also studied.

scholarly journals MECHANICAL PROPERTIES OF PVA NANOFIBER TEXTILES WITH INCORPORATED NANODIAMONDS, COPPER AND SILVER IONS

2015 ◽  
Vol 55 (1) ◽  
pp. 14-21
Author(s):  
Kateřina Indrová ◽  
Zdeněk Prošek ◽  
Jaroslav Topič ◽  
Pavla Ryparová ◽  
Václav Nežerka ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Thermal Stabilization ◽  
Silver Ions ◽  
Elastic Stiffness ◽  
Poly Vinyl Alcohol ◽  
Minor Effect ◽  
Electrospinning Method ◽  
A Minor ◽  
Cu Ions

The unique properties of nanotextiles based on poly(vinyl-alcohol) (PVA) manufactured using electrospinning method have been known and exploited for many years. Recently, the enrichment of nanofiber textiles with nanoparticles, such as ions or nanodiamond particles (NDP), has become a popular way to modify the textile mechanical, chemical and physical properties. The aim of our study is to investigate the macromechanical properties of PVA nanotextiles enriched with NDP, silver (Ag) and copper (Cu) ions. The nanofiber textiles of a various surface weight were prepared from 16% PVA solution, while glyoxal and phosphoric acid were used as cross-linking agents. The copper and silver ions were diluted in aqueous solution and NDP were dispersed into the fibers by ultrasound homogenization. All but one set of samples were exposed to the temperature of 140 °C for 10 minutes. The samples without thermal stabilization exhibited significantly lower elastic stiffness and tensile strength. Moreover, the results of tensile testing indicate that the addition of dispersed nanoparticles has a minor effect on the mechanical properties of textiles and contributes rather to their reinforcement. On the other hand, the lack of thermal stabilization results in a poor interconnection of individual nanofiber layers and the non-stabilized textiles exhibit a lower elastic stiffness and reduced tensile strength.

Effect of MoS2 Nanosheet Fillers on Poly(vinyl alcohol) Nanofibre Composites Obtained by the Electrospinning Method

2020 ◽  
Vol 28 (3(141)) ◽  
pp. 62-67
Author(s):  
Bin Yuan ◽  
Jun Liu ◽  
Lei Qiu ◽  
Meng-Jie Chang ◽  
Ya-Qing Li
Keyword(s):  
Thermal Analysis ◽  
Mechanical Stability ◽  
Inorganic Materials ◽  
Poly Vinyl Alcohol ◽  
Two Dimensional ◽  
Mos2 Nanosheets ◽  
Electrospinning Method ◽  
Mos2 Nanosheet ◽  
Membrane Engineering ◽  
Fibre Morphology

The graphene-like two dimensional (2D) inorganic materials have been been shown great interest for a variety of applications. In this work, polymer composite nanofibres containing molybdenum disulfide (MoS2) nanosheets were obtained by electrospinning. The MoS2 nanosheets were well dispersed inside the fibres, and the nanofibres maintained the fibre morphology well with the MoS2 nanosheets embedded. The incorporation of MoS2 nanosheets changes polymer nanofibre morphology from round to ribbon-like. Moreover, through thermogravimetric (TG) analysis and dynamic mechanical thermal analysis (DMTA) measurements, it was found that the MoS2 nanosheets as an additive material led to an increase in thermal stability and in the storage modulus. This work comprises an extensive approach to producing a novel 2D inorganic-organic composite structure, which should be applicable for membrane engineering with enhanced thermal and mechanical stability.

scholarly journals Electrospun Nanofibers of Natural and Synthetic Polymers as Artificial Extracellular Matrix for Tissue Engineering

Nanomaterials ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 21
Author(s):  
Mina Keshvardoostchokami ◽  
Sara Seidelin Majidi ◽  
Peipei Huo ◽  
Rajan Ramachandran ◽  
Menglin Chen ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Polymer Composite ◽  
Electrospun Nanofibers ◽  
Synthetic Polymer ◽  
Inorganic Materials ◽  
Host Cells ◽  
Natural Polymer ◽  
Reinforced Polymers ◽  
Nanofibrous Scaffolds ◽  
Artificial Extracellular Matrix

Many types of polymer nanofibers have been introduced as artificial extracellular matrices. Their controllable properties, such as wettability, surface charge, transparency, elasticity, porosity and surface to volume proportion, have attracted much attention. Moreover, functionalizing polymers with other bioactive components could enable the engineering of microenvironments to host cells for regenerative medical applications. In the current brief review, we focus on the most recently cited electrospun nanofibrous polymeric scaffolds and divide them into five main categories: natural polymer-natural polymer composite, natural polymer-synthetic polymer composite, synthetic polymer-synthetic polymer composite, crosslinked polymers and reinforced polymers with inorganic materials. Then, we focus on their physiochemical, biological and mechanical features and discussed the capability and efficiency of the nanofibrous scaffolds to function as the extracellular matrix to support cellular function.

Modeling tensile strength and suture retention of polycaprolactone electrospun nanofibrous scaffolds by artificial neural networks

2021 ◽  
Vol 26 ◽  
pp. 102115
Author(s):  
B.S. Reddy ◽  
Kim Hong In ◽  
Bharat B. Panigrahi ◽  
Uma Maheswera Reddy Paturi ◽  
K.K. Cho ◽  
...  
Keyword(s):  
Neural Networks ◽  
Tensile Strength ◽  
Artificial Neural Networks ◽  
Nanofibrous Scaffolds ◽  
Artificial Neural
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