scholarly journals Type 1 Kounis Syndrome in Patient with Idiopathic Anaphylaxis

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Tajda Keber ◽  
Jana Makuc ◽  
Gregor Sekavčnik

Kounis syndrome represents the concurrence of acute coronary syndromes or anginal pain with allergic, hypersensitivity, and anaphylactic reactions. It can be associated with normal coronary angiogram or preexistent coronary pathology. Idiopathic anaphylaxis is defined as anaphylaxis without any identifiable precipitating agent or event. We present a case of male who experienced attacks of dyspnoea, hypoxemia, hypotension, purple-red skin, and chest pain over several years. He was diagnosed with idiopathic anaphylaxis. Based on the pattern of chest pain of ischemic origin during the attacks he was retrospectively diagnosed with Kounis syndrome.

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Rogerio Teixeira ◽  
Carolina Lourenco ◽  
Elisabete Jorge ◽  
Rui Baptista ◽  
Natalia Antonio ◽  
...  

Background: Revascularization is a crucial therapy in acute coronary syndromes (ACS). Purpose: to assess ACS patients outcomes, stratified according to the coronary angiography and/or angioplasty. Population and methods: 786 consecutive ACS patients submitted to an invasive strategy, divided in 3 groups: A (n=111) normal coronary angiogram; B (n=327) fully revascularized; C (n=348) incomplete revascularization. A 1-year follow up targeting major adverse cardiovascular events (MACE) was performed. Results: Group A had more females (38.7 vs 21.1 vs 24.4% p<0.01), patients were more admitted for unstable angina (37.3 vs 14.9 vs 17.9% p<0.01) and had a higher left ventricular ejection fraction (LVEF). Group B were more on previous statin therapy, had more often an admission for ST elevation acute myocardial infarction (17.3 vs 51.7 vs 42.4% p<0.001) and higher peak levels of cardiac biomarkers. Group C were older and had more frequently a previous history of coronary disease. Group C patients had a worse in-hospital mortality (1.8 vs 1.2 vs 7.5% p<0.01) and morbidity. The MACE free survival rate was significantly lower for group C (92.9% vs. 92.9% vs. 78.2%; log rank p<0.001). In a multivariate Cox regression analysis, incomplete revascularization remained an independent predictor of MACE at 1 year (HR 2.74, CI 1.50 – 4.94), in a model that included, age, gender, LVEF, diabetes, coronary anatomy, and admission diagnosis. Conclusion: Our data strongly support the use of an aggressive invasive strategy in ACS, aimed at achieving full revascularization, as these patients had the same medium term prognosis as those with normal coronary angiogram.


Author(s):  
Hiroaki Kawano ◽  
Yasuhiro Nagayoshi ◽  
Hirofumi Soejima ◽  
Yasuaki Tanaka ◽  
Jun Hokamaki ◽  
...  

2012 ◽  
Vol 30 (1) ◽  
pp. 57-60
Author(s):  
Taku Taira ◽  
Breena R. Taira ◽  
Jasmine Chohan ◽  
Daniel Dickinson ◽  
Regina M. Troxell ◽  
...  

2012 ◽  
Vol 159 (5) ◽  
pp. 391-396 ◽  
Author(s):  
Sherezade Khambatta ◽  
Michael E. Farkouh ◽  
R. Scott Wright ◽  
Guy S. Reeder ◽  
Peter A. McCullough ◽  
...  

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e032834 ◽  
Author(s):  
Abdulrhman Alghamdi ◽  
Eloïse Cook ◽  
Edward Carlton ◽  
Aloysius Siriwardena ◽  
Mark Hann ◽  
...  

IntroductionWithin the UK, chest pain is one of the most common reasons for emergency (999) ambulance calls and the most common reason for emergency hospital admission. Diagnosing acute coronary syndromes (ACS) in a patient with chest pain in the prehospital setting by a paramedic is challenging. The Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision rule is a validated tool used in the emergency department (ED) to stratify patients with suspected ACS following a single blood test.We are seeking to evaluate the diagnostic accuracy of the T-MACS decision aid algorithm to ‘rule out’ ACS when used in the prehospital environment with point-of-care troponin assays. If successful, this could allow paramedics to immediately rule out ACS for patients in the ‘very low risk’ group and avoid the need for transport to the ED, while also risk stratifying other patients using a single blood sample taken in the prehospital setting.Methods and analysisWe will recruit patients who call emergency (999) ambulance services where the responding paramedic suspects cardiac chest pain. The data required to apply T-MACS will be prospectively recorded by paramedics who are responding to each patient. Paramedics will be required to draw a venous blood sample at the time of arrival to the patient. Blood samples will later be tested in batches for cardiac troponin, using commercially available troponin assays. The primary outcome will be a diagnosis of acute myocardial infarction, established at the time of initial hospital admission. The secondary outcomes will include any major adverse cardiac events within 30 days of enrolment.Ethics and disseminationThe study obtained approval from the National Research Ethics Service (reference: 18/ES/0101) and the Health Research Authority. We will publish our findings in a high impact general medical journal.Trial registration numberRegistration number: ClinicalTrials.gov, study ID: NCT03561051


2017 ◽  
Vol 207 (5) ◽  
pp. 195-200 ◽  
Author(s):  
Louise Cullen ◽  
Jaimi H Greenslade ◽  
Tracey Hawkins ◽  
Chris Hammett ◽  
Shanen O'Kane ◽  
...  

2003 ◽  
pp. 43-43
Author(s):  
Shashiraj E ◽  
Babu Palatty ◽  
Amiya Chakraborty

2021 ◽  
Vol 17 (1) ◽  
pp. 3-6 ◽  
Author(s):  
Bhurint Siripanthong ◽  
Thomas C Hanff ◽  
Michael G Levin ◽  
Mahesh K Vidula ◽  
Mohammed Y Khanji ◽  
...  

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