scholarly journals Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Xiaoquan Huang ◽  
Lili Ma ◽  
Xiaoqing Zeng ◽  
Jian Wang ◽  
Jie Chen ◽  
...  

Background. Esophagogastric variceal hemorrhage leads to challenging situation in chronic kidney disease patients on maintenance hemodialysis. Aims. To determine the safety and efficacy of endoscopic approaches to patients with hemodialysis-dependent concomitant with esophagogastric varices. Methods. Medical records were reviewed from January 1, 2004, to December 31, 2015, in our hospital. Five consecutive hemodialysis-dependent patients with variceal hemorrhage who underwent endoscopic treatments were retrospectively studied. Results. The median age of the patients was 54 years (range 34–67 years) and the median follow-up period was 21.3 months (range 7–134 months). All the patients received a total of three times heparin-free hemodialysis 24 hours before and no more than 24 hours and 72 hours after endoscopic treatment. They successfully had endoscopic variceal ligation, endoscopic injection sclerotherapy, and/or N-butyl cyanoacrylate injection. The short-term efficacy is satisfying and long-term follow-up showed episodes of rebleeding. Conclusions. Endoscopic approaches are the alternative options in the treatment of upper gastroenterology variceal hemorrhage in hemodialysis-dependent patients without severe complications.

Endoscopy ◽  
1987 ◽  
Vol 19 (05) ◽  
pp. 181-184 ◽  
Author(s):  
T. Sauerbruch ◽  
M. Weinzierl ◽  
H. Ansari ◽  
G. Paumgartner

1986 ◽  
Vol 1 (3) ◽  
pp. 217-220 ◽  
Author(s):  
P. Reddy ◽  
J. Wickers ◽  
T. Terry ◽  
P. Lamont ◽  
J. Moller ◽  
...  

Two consecutive randomized trials following injection sclerotherapy for varicose veins compared 3 and 6 weeks bandaging in 148 patients and 1 to 3 weeks bandaging in 130 patients. Objective assessment and patient's symptoms, using a scoring system, correlated well and showed that there was no difference whatsoever between 3 and 6 weeks' bandaging after a 6 year follow-up. In the second trial, the patients who were bandaged for 3 weeks were significantly better (P < 0.001) than after only one week of bandaging at a maximum follow up of 4 years. Long term follow up of injection sclerotherapy for primary varicose veins suggests that 3 weeks is superior to 1 week bandaging, but that there is no additional advantage in continuing bandaging for six weeks.


2018 ◽  
Vol 11 (6) ◽  
pp. 487-492 ◽  
Author(s):  
Ryuta Shigefuku ◽  
Tsunamasa Watanabe ◽  
Takuro Mizukami ◽  
Kotaro Matsunaga ◽  
Nobuhiro Hattori ◽  
...  

Children ◽  
2021 ◽  
Vol 8 (10) ◽  
pp. 875
Author(s):  
Raffaella Cocomazzi ◽  
Alessia Salatto ◽  
Vittoria Campanella ◽  
Valentina Pastore ◽  
Cosetta Maggipinto ◽  
...  

This paper is designed to evaluate the results (at long-term follow-up of) children affected by dilating VUR. Our attention was focused on how VUR grade, laterality, bladder dysfunction (BD), the double renal system, and the type of bulking substance may affect VUR resolution in the long-term period. The charts of 93 children with dilating VUR who underwent endoscopic treatment (ET) and with a minimum post-operative follow-up of 7 years were reviewed (mean follow-up time was 9.6 + 1.4). The majority of patients had severe and bilateral VUR. Polydimetilsiloxane or hyaluronic acid/dextranomer (PDS or Ha/Dx) were used as bulking agents. VUR persistence following endoscopic injection was independent with respect to grade, laterality, duplex renal system, and BD. However, the rate of VUR persistence was significantly higher in children with BD. Children treated with Ha/Dx had a higher rate of VUR persistence. This research demonstrated that ET of VUR is also effective at very long term follow up (and without the development of significant complications). We also showed that patients treated with absorbable bulking agents such as Ha/Dx may experience a higher recurrence rate at the long-term follow-up). We also confirm that the only preoperative condition affecting VUR recurrence was bladder dysfunction.


2006 ◽  
Vol 30 (7) ◽  
pp. 1329-1337 ◽  
Author(s):  
Shabir Ahmad Qazi ◽  
Kamran Khalid ◽  
Abdul Majeed Abdul Hameed ◽  
Khalid Al-Wahabi ◽  
Radwan Galul ◽  
...  

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.


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