scholarly journals Colon Capsule Endoscopy: Review and Perspectives

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
David Friedel ◽  
Rani Modayil ◽  
Stavros Stavropoulos
Keyword(s):  
Capsule Endoscopy ◽  
Prior Experience ◽  
Current Status ◽  
Entire Colon ◽  
Optical Colonoscopy ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule

Colon capsule endoscopy utilizing PillCam COLON 2 capsule allows for visualization potentially of the entire colon and is currently approved for patients who cannot withstand the rigors of traditional optical colonoscopy (OC) and associated sedation as well as those that had an OC that was incomplete for technical reasons other than a poor preparation. We will then describe the prior experience and current status of colon capsule endoscopy.

scholarly journals Prospective study of factors important to achieve observation of the entire colon on colon capsule endoscopy

2016 ◽  
Vol 10 (1) ◽  
pp. 20-31
Author(s):  
Junichi Sato ◽  
Masanao Nakamura ◽  
Osamu Watanabe ◽  
Takeshi Yamamura ◽  
Kohei Funasaka ◽  
...  
Keyword(s):  
Water Intake ◽  
Capsule Endoscopy ◽  
Entire Colon ◽  
Independent Predictive Factor ◽  
Logistic Analysis ◽  
Air Supply ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule ◽  
Patient Stress ◽  
Written Informed Consent

Background: Colon capsule endoscopy (CCE) is a procedure in which capsule swallowing facilitates observation of the lumen of the entire digestive tract. It does not require an air supply, and is a noninvasive procedure with a markedly low risk of adverse events in comparison with conventional colonoscopy (CS). It reduces patient stress, and may be acceptable to patients. A limitation of this procedure is that the entire colon observation rate (CCE excretion rate, completed CCE rate) is not 100%. In this study, we prospectively investigated clinical factors important to achieve observation of the entire colon on CCE. Methods: The participants were 70 patients for whom CCE was scheduled, and from whom written informed consent regarding participation in this study was obtained. We selected patient background/examination factors, and analyzed all factors involved in observation of the entire colon and factors for completion of the CCE within 4 h after the start of examination using multivariate analysis. Results: Of the 70 enrolled patients, 64 were analyzed, excluding 6. On multiple logistic analysis, only a water intake of ⩾12.0 ml/min during examination [ p = 0.025, odds ratio (OR): 46.753, 95% confidence interval (CI): 1.630–1341.248] was identified as an independent predictive factor involved in observation of the entire colon. With respect to factors involved in the completion of CCE within 4 h, multiple logistic analysis showed that a body mass index (BMI) of ⩾25 ( p = 0.039, OR: 13.723, 95% CI: 1.135–165.913), the absence of constipation ( p = 0.030, OR: 13.988, 95% CI: 1.287–152.047), and a water intake of ⩾12.0 ml/min during examination ( p = 0.004, OR: 12.028, 95% CI: 2.225–65.029) were independent predictive factors. Conclusions: Completion of a CCE was most closely related to water intake per hour. In addition to water intake, CCE-promoting factors included a high BMI and the absence of constipation.

scholarly journals Current status of colon capsule endoscopy

2020 ◽  
Author(s):  
Naoki Hosoe ◽  
Kenji J. L. Limpias Kamiya ◽  
Yukie Hayashi ◽  
Tomohisa Sujino ◽  
Haruhiko Ogata ◽  
...  
Keyword(s):  
Capsule Endoscopy ◽  
Current Status ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule

scholarly journals Diagnostic Yields and Clinical Impacts of Capsule Endoscopy

Diagnostics ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1842
Author(s):  
Seung Min Hong ◽  
Sung Hoon Jung ◽  
Dong Hoon Baek
Keyword(s):  
Small Bowel ◽  
Capsule Endoscopy ◽  
Diagnostic Yield ◽  
Critical Role ◽  
Current Status ◽  
Entire Small Bowel ◽  
Colon Capsule Endoscopy ◽  
Bowel Diseases ◽  
Colon Capsule ◽  
Bowel Disorders

Observing the entire small bowel is difficult due to the presence of complex loops and a long length. Capsule endoscopy (CE) provides a noninvasive and patient-friendly method for visualizing the small bowel and colon. Small bowel capsule endoscopy (SBCE) has a critical role in the diagnosis of small bowel disorders through the direct observation of the entire small bowel mucosa and is becoming the primary diagnostic tool for small bowel diseases. Recently, colon capsule endoscopy (CCE) was also considered safe and feasible for obtaining sufficient colonic images in patients with incomplete colonoscopy, in the absence of bowel obstruction. This review article assesses the current status of CE in terms of the diagnostic yield and the clinical impact of SBCE in patients with obscure gastrointestinal bleeding, who have known or suspected Crohn’s disease, small bowel tumor and inherited polyposis syndrome, celiac disease, and those who have undergone CCE.

scholarly journals Back-to-back colon capsule endoscopy and optical colonoscopy in colorectal cancer screening individuals

2018 ◽  
Vol 20 (6) ◽  
pp. 479-485 ◽  
Author(s):  
M. Kobaek-Larsen ◽  
R. Kroijer ◽  
A.-K. Dyrvig ◽  
M. M. Buijs ◽  
R. J. C. Steele ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
Capsule Endoscopy ◽  
Optical Colonoscopy ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule

Sa1580 Impact of Colon Capsule Endoscopy on Medical Decision Making in Patients With Incomplete Optical Colonoscopy

2011 ◽  
Vol 73 (4) ◽  
pp. AB214
Author(s):  
Onofre Alarcón-Fernández ◽  
Laura Ramos ◽  
Zaida Adrián-De-Ganzo ◽  
Antonio Z. Gimeno-García ◽  
David Nicolás-Pérez ◽  
...  
Keyword(s):  
Decision Making ◽  
Capsule Endoscopy ◽  
Medical Decision Making ◽  
Medical Decision ◽  
Optical Colonoscopy ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule

scholarly journals Second-generation colon capsule endoscopy for detection of colorectal polyps: Systematic review and meta-analysis of clinical trials

2021 ◽  
Vol 09 (04) ◽  
pp. E562-E571
Author(s):  
Tobias Möllers ◽  
Matthias Schwab ◽  
Lisa Gildein ◽  
Michael Hoffmeister ◽  
Jörg Albert ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Diagnostic Accuracy ◽  
Capsule Endoscopy ◽  
Bowel Preparation ◽  
Meta Analysis ◽  
Optical Colonoscopy ◽  
Crc Screening ◽  
Colon Capsule Endoscopy ◽  
Colon Capsule

Abstract Background and study aims Adherence to colorectal cancer (CRC) screening is still unsatisfactory in many countries, thereby limiting prevention of CRC. Colon capsule endoscopy (CCE), a minimally invasive procedure, could be an alternative to fecal immunochemical tests or optical colonoscopy for CRC screening, and might increase adherence in CRC screening. This systematic review and meta-analysis evaluates the diagnostic accuracy of CCE compared to optical colonoscopy (OC) as the gold standard, adequacy of bowel preparation regimes and the patient perspective on diagnostic measures. Methods We conducted a systematic literature search in PubMed, EMBASE and the Cochrane Register for Clinical Trials. Pooled estimates for sensitivity, specificity and the diagnostic odds ratio with their respective 95 % confidence intervals (CI) were calculated for studies providing sufficient data. Results Of 840 initially identified studies, 13 were included in the systematic review and up to 9 in the meta-analysis. The pooled sensitivities and specificities for polyps ≥ 6 mm were 87 % (95 % CI: 83 %–90 %) and 87 % (95 % CI: 76 %–93 %) in 8 studies, respectively. For polyps ≥ 10 mm, the pooled estimates for sensitivities and specificities were 87 % (95 % CI: 83 %–90 %) and 95 % (95 % CI: 92 %–97 %) in 9 studies, respectively. A patients’ perspective was assessed in 31 % (n = 4) of studies, and no preference of CCE over OC was reported. Bowel preparation was adequate in 61 % to 92 % of CCE exams. Conclusions CCE provides high diagnostic accuracy in an adequately cleaned large bowel. Conclusive findings on patient perspectives require further studies to increase acceptance/adherence of CCE for CRC screening.

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