scholarly journals A 27-Year-Old Severely Immunosuppressed Female with Misleading Clinical Features of Disseminated Cutaneous Sporotrichosis

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Atiyah Patel ◽  
Victor Mudenda ◽  
Shabir Lakhi ◽  
Owen Ngalamika
Keyword(s):  
Clinical Features ◽  
Kaposi's Sarcoma ◽  
Sporothrix Schenckii ◽  
Rare Condition ◽  
Cutaneous Infection ◽  
The World ◽  
Multisystemic Disease ◽  
Direct Inoculation ◽  
Atypical Presentations ◽  
Pulmonary Focus

Sporotrichosis is a subacute or chronic granulomatous mycosis caused by fungus of theSporothrix schenckiicomplex. It is considered to be a rare condition in most parts of the world. It mostly causes cutaneous infection but can also cause multisystemic disease. Unlike most deep cutaneous mycoses which have a primary pulmonary focus, it is usually caused by direct inoculation of the fungus into the skin causing a classical linear, lymphocutaneous nodular eruption. However, atypical presentations of the condition can occur especially in immunosuppressed individuals. We report the case of a severely immunosuppressed female who presented with disseminated cutaneous sporotrichosis which was initially diagnosed and treated as disseminated cutaneous Kaposi’s sarcoma.

A Rare Case of Congenital Missing Mandibular Second Molar: Report and Review of Literature

2020 ◽  
Author(s):  
Deepashri H Kambalimath
Keyword(s):  
Tooth Development ◽  
Rare Condition ◽  
Review Of Literature ◽  
Indian Literature ◽  
Missing Teeth ◽  
Second Molar ◽  
The World ◽  
Mandibular Second Molar ◽  
Sporadic Cases ◽  
Genetic And Environmental Factors

Congenital missing permanent second molar is an extremely rare condition. Non syndromic mandibular second molar agenesis associated with other anomalies has occasionally been reported in literature, but isolated sporadic cases are rarely observed. Number of interactions between genetic and environmental factors during the process of tooth development might be the causative etiology for agenesis. This report presents an isolated case of hypodontia with absence of bilateral mandibular second molar agenesis in a healthy 18 year old female patient is presented and literature review on prevalence of most missing teeth with incidence of missing second molar in various regions of the world and in various regions of Indian continent is presented. No such case has been reported in Indian literature so far.

scholarly journals POS0815 CLINICAL CHARACTERISTICS, IMAGING PHENOTYPE, AND LONG-TERM OUTCOMES OF TAKAYASU ARTERITIS PATIENTS WITH HYPERTENSION

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 661.1-661
Author(s):  
Y. Sun ◽  
L. Ma ◽  
H. Chen ◽  
C. Rongyi ◽  
L. Jiang
Keyword(s):  
Blood Pressure ◽  
Adverse Events ◽  
Clinical Features ◽  
Takayasu Arteritis ◽  
Pressure Control ◽  
Free Survival ◽  
The World ◽  
Cluster 2

Background:Hypertension occurred in 30-80% of TAK patients around the world. The occurrence of hypertension might severely worsen TAK prognosis. Nevertheless, data describing the specific imaging features in hypertensive TAK patients and the associations between hypertensive severity, blood pressure control status and long-term outcome were still lacking.Objectives:To investigate the characteristics and associations of hypertensive characteristics with adverse events-free survival in Takayasu arteritis (TAK) patients with hypertension.Methods:This research was based on a prospectively on-going observational cohort-East China Takayasu Arteritis (ECTA) cohort. In all, 618 TAK patients, who registered in the ECTA cohort up to December 2019, were enrolled. The main outcome was the adverse-events-free survival among hypertensive TAK patients during the follow-up ended on August 2020.Results:Totally, 204 (33.0%) patients suffered from hypertension, with 48 (23.5%), 62 (30.4%), and 94 (46.1%) mild, moderate, and severe hypertension, respectively. Cluster analysis indicated three imaging phenotypes for hypertensive TAK patients: Cluster 1: involvement of the abdominal aorta and/or renal artery (n=56, 27.5%); Cluster 2: involvement of the ascending aorta, thoracic aorta, and the aortic arch and its branches (n=38, 18.6%); Cluster 3: combined involvement of Cluster 1 and Cluster 2 (n=111, 54.4%). By the end of the follow-up, the blood pressure control rate was 50.8%, while the adverse-events-free survival was 67.9% in the entire hypertensive population. Multivariate Cox regression analysis indicated that well-controlled blood pressure (HR=2.13, 95%CI 1.32–3.78, p=0.047), co-existence of severe aortic valve regurgitation (HR=0.87, 95%CI 0.64–0.95, p=0.043), Cluster 1 (HR=0.69, 95%CI 0.48–0.92, p=0.017) and Cluster 3 (HR=0.72, 95%CI 0.43–0.94, p=0.048) imaging phenotype was associated with the adverse-events-free survival.Conclusion:Patients with controlled hypertension showed better adverse-events-free survival, while those with the Cluster 1 imaging phenotype were more likely to suffer from worse adverse-events-free survival. Hypertension occurred in 30-80% of TAK patients around the world. The occurrence of hypertension might severely worsen TAK prognosis.References:[1]Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol 2002; 55:481–6.[2]Watanabe Y, Miyata T, Tanemoto K. Current clinical features of new patients with Takayasu arteritis observed from a cross-country research in Japan: age and sex specificity. Circulation 2015; 132:1701–9.[3]Yilmaz N, Can M, Oner FA, et al. Impaired quality of life, disability and mental health in Takayasu’s arteritis. Rheumatol. (Oxford) 2013; 52:1898–904.[4]Laurent A, Julien H, Nicolas L, et al. Takayasu arteritis in France: a single-center retrospective study of 82 cases comparing white, North African, and black patients. Medicine 2010; 89:1–17.[5]Mwipatayi BP, Jeffery PC, Beningfield SJ, et al. Takayasu arteritis: clinical features and management: report of 272 cases. ANZ J Surg 2005; 75:110–7.Disclosure of Interests:None declared

Aspergillus pachymeningitis mimicking nasopharyngeal carcinoma

2010 ◽  
Vol 125 (1) ◽  
pp. 103-107 ◽  
Author(s):  
H S Chan ◽  
H Y Yuen ◽  
W K Ng ◽  
A C Vlantis ◽  
A T Ahuja ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
World Literature ◽  
Clinical Course ◽  
Rare Condition ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Radiological Findings ◽  
Cranial Nerve Palsies ◽  
The World ◽  
Multiple Cranial Nerve

AbstractObjectives:We report a case of otogenic fungal pachymeningitis in a diabetic patient who presented with multiple cranial nerve palsies and nasopharyngeal swelling.Methods:We present a case report, we describe the investigations, management and clinical course of fungal pachymeningitis, and we present a review of the world literature on fungal and non-fungal pachymeningitis.Results:To our knowledge, this is the first report of fungal pachymeningitis with magnetic resonance imaging features suggestive of nasopharyngeal carcinoma. It is also the first reported case with aspergillus cultured from both a dural biopsy and the ear canal.Conclusion:Fungal pachymeningitis is a rare condition which may present to otorhinolaryngologists. Its clinical and radiological findings can be confused with those of nasopharyngeal carcinoma; fungal pachymeningitis should thus be included in the differential diagnosis of nasopharyngeal carcinoma.

Kawasaki Syndrome

1996 ◽  
Vol 17 (5) ◽  
pp. 153-162
Author(s):  
Marian E. Melish
Keyword(s):  
Clinical Features ◽  
Etiologic Agent ◽  
Kawasaki Syndrome ◽  
Periarteritis Nodosa ◽  
Cardiac Effects ◽  
Clinical Criteria ◽  
Coronary Aneurysms ◽  
The World ◽  
Primary Physicians ◽  
Children First

Kawasaki syndrome (KS) is an acute, febrile, self-limited, multisystem vasculitis that almost exclusively affects young children. First described in 1967 by Dr. Tomisaku Kawasaki of Tokyo, Japan, it now has been recognized as occurring in all regions of the world among children of multiple and diverse ethnic groups. Its occurrence is common enough in all parts of North America that primary physicians should be familiar with its diagnosis and treatment. Originally thought to be a benign febrile exanthem, it soon was recognized that fever could be prolonged and that significant adverse cardiac effects were common, especially the development of coronary aneurysms that could lead to myocardial infarction and sudden death. Fatal KS is a multisystem vasculitis indistinguishable from infantile periarteritis nodosa (IPN); until the discovery of KS, IPN had been a condition diagnosed only at autopsy. Dr. Kawasaki's enduring contribution is the recognition and description of the major clinical features of this unique disease, which only rarely causes death. The clinical criteria he described remain the basis of all clinical and epidemiologic descriptions in use today. Although effective therapy has been discovered, the etiology of the disease remains unknown. The acute, febrile, self-limited nature of the disease and its clinical features of fever; rash; and menigeal, joint, hepatic, and mucous membrane inflammation strongly suggest that the etiologic agent is microbial.

Pleomorphic adenoma of the external auditory canal: a case report and review of the literature

1996 ◽  
Vol 110 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Hidetoshi Haraguchi ◽  
Hitoshi Hentona ◽  
Hidekazu Tanaka ◽  
Atsushi Komatuzaki
Keyword(s):  
Case Report ◽  
Natural History ◽  
Pleomorphic Adenoma ◽  
Clinical Features ◽  
External Auditory Canal ◽  
World Wide ◽  
Review Of The Literature ◽  
The World ◽  
History Of ◽  
Uncommon Tumour

AbstractPleomorphic adenoma arising in the external auditory canal is rare. We report the case of a 38-year-old man. To better grasp the clinical features and natural history of this uncommon tumour, we also reviewed the world wide literature and found 24 similar cases, which we analysed together with our own.

scholarly journals Did you rule out neurosyphilis?

2010 ◽  
Vol 4 (4) ◽  
pp. 338-345 ◽  
Author(s):  
Ricardo Nitrini ◽  
Anderson Rodrigues Brandão de Paiva ◽  
Leonel Tadao Takada ◽  
Sonia Maria Dozzi Brucki
Keyword(s):  
Developing Countries ◽  
Lumbar Puncture ◽  
Median Time ◽  
Neuropsychiatric Symptoms ◽  
Rare Condition ◽  
Developed Countries ◽  
Behavioral Neurology ◽  
The World ◽  
The University ◽  
Rule Out

Abstract Neurosyphilis, formerly a frequent cause of dementia, is now a rare condition in developed countries. However, syphilis remains common in many developing countries, where adequate diagnosis and treatment of early syphilis may be lacking, increasing the chances of neurosyphilis and prevalence of syphilitic dementia. Objectives: To present cases of syphilitic dementia seen in a cognitive and behavioral neurology unit in Brazil, emphasizing their first symptoms and the challenges they posed in diagnosis. Methods: At our unit of the Hospital das Clínicas of the University of São Paulo, all patients are submitted to blood treponemal tests. When the test is positive, a lumbar puncture is performed. We retrospectivelly reviewed all cases of neurosyphilis seen in our unit from January 1991 to November 2009. Results: Nine cases of neurosyphilis (0.77% of the 1160 cases in our files) were identified over the period. Patients with neurosyphilis were all men, had a mean age of 47.8 (±13.0) years (median of 43 years), and presented with various neuropsychiatric syndromes and elusive diagnoses. The median time from onset of symptoms to diagnosis was 24 months and only one patient made a full recovery after treatment. Conclusions: Neurosyphilis is not frequent but remains present, causing several types of neuropsychiatric syndromes. As it is very simple to rule out neurosyphilis by performing a blood treponemal test, this test should be performed in all patients with neuropsychiatric symptoms, particularly in regions of the world where syphilis is still a commonly occurring disease.

scholarly journals COVID-19 and Heart: From Clinical Features to Pharmacological Implications

2020 ◽  
Vol 9 (6) ◽  
pp. 1944 ◽  
Author(s):  
Vincenzo Russo ◽  
Roberta Bottino ◽  
Andreina Carbone ◽  
Anna Rago ◽  
Andrea Antonio Papa ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Disease Management ◽  
Severe Acute Respiratory Syndrome ◽  
Clinical Outcome ◽  
Hospital Admission ◽  
Clinical Features ◽  
Epidemiological Data ◽  
Human Coronavirus ◽  
Highly Pathogenic ◽  
The World

A highly pathogenic human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been recently recognized in Wuhan, China, as the cause of the coronavirus disease 2019 (COVID-19) outbreak which has spread rapidly from China to other countries in the world, causing a pandemic with alarming morbidity and mortality. The emerging epidemiological data about COVID-19 patients suggest an association between cardiovascular diseases (CVD) and SARS-CoV-2 infection, in term of clinical features at hospital admission and prognosis for disease severity. The aim of our review is to describe the cardiological features of COVID-19 patients at admission, the acute cardiac presentation, the clinical outcome for patients with underlying CVD and the pharmacological implications for disease management.

Clinical features of Kaposi's sarcoma: experience from a Taiwanese medical center

2019 ◽  
Vol 58 (12) ◽  
pp. 1388-1397 ◽  
Author(s):  
Alice Ya‐Yun Huang ◽  
Chi‐Ling Lin ◽  
Gwo‐Shing Chen ◽  
Stephen Chu‐Sung Hu
Keyword(s):  
Clinical Features ◽  
Kaposi's Sarcoma ◽  
Medical Center ◽  
Kaposi’S Sarcoma

AIDS as a moral metaphor: An analysis of the politics of the ‘Third Epidemic’

1989 ◽  
Vol 30 (2) ◽  
pp. 243-273 ◽  
Author(s):  
Laurence J. Ray
Keyword(s):  
Sexual Intercourse ◽  
Sexually Transmitted Disease ◽  
Transmitted Disease ◽  
Rare Condition ◽  
Sexual Contact ◽  
Traditional Values ◽  
Sexually Transmitted ◽  
The Third ◽  
Social Events ◽  
The World

This paper examines some of the moral meanings of aids, and argues that in addition to understanding aids in the context of the sexual counter-revolution, it also needs to be placed in the wider context of global economic and ideological crises, and the ‘New Right's’ struggle for hegemony. Denis Altman refers to aids as ‘the most political of diseases’ (Altman 1986, p. 11). A few years ago, Evans Stark pointed out that all epidemics are ‘social events’, even though they may appear as natural, random phenomena. This is because they have become the focus of struggles for control over resources (principally housing, medicines, and sanitation) (Stark 1977). Epidemics further tend to throw into relief deeply held social tensions and anxieties, which can become triggers for social reorganisation around traditional values. It is not difficult to see how this is the case with aids, which is infused in particular with tensions over sexuality and desire. In relation to this it is important to emphasize first, that sexual contact is estimated to be responsible for around two-thirds of reported aids cases amongst adults in the U.S.A. (Gracie et al. 1986), but it is not actually an exclusively sexually transmitted disease; and secondly that compared with other major causes of morbidity and mortality, aids remains a relatively rare condition in many parts of the world. It is sociologically significant though, that the two major routes of transmission, IV use and penetrative sexual intercourse, involve issues of control over body boundaries.

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