scholarly journals A Giant Aggressive Angiomyxoma of the Pelvis Misdiagnosed as Incarcerated Femoral Hernia: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Alper Sozutek ◽  
Oktay Irkorucu ◽  
Enver Reyhan ◽  
Kemal Yener ◽  
Ali Ayberk Besen ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Femoral Hernia ◽  
Surgical Excision ◽  
Reproductive Age ◽  
Positive Staining ◽  
Aggressive Angiomyxoma ◽  
Common Symptom ◽  
High Tendency ◽  
Gynecological Malignancy ◽  
Complete Surgical Excision

Aggressive angiomyxoma (AA) is an uncommon mesenchymal tumor that is mostly derived from the female pelvic and perineal regions. AA is a locally infiltrative slow growing tumor with a marked tendency to local recurrence. Painless swelling located around the genitofemoral region is the common symptom; thus, it is often misdiagnosed as a gynecological malignancy or a groin hernia. A 35-year-old female patient who previously underwent surgery for left femoral hernia operation resulting in surgical failure was reoperated for a giant AA located in the pelvis. The tumor was completely excised with free margins. Histopathologic examination revealed an AA. The tumor size was measured as 24 × 12 × 6 cm with a weight of 4.2 kg. Immunohistochemically, the cells show positive staining with vimentin, desmin, estrogen, and progesterone receptor. S100, MUC4, CD34, and SMA were negative in the tumor cells. AA should be considered in the differential diagnosis of any painless swelling located in the genitofemoral region, particularly in women of reproductive age. The principle treatment should be complete surgical excision with tumor-free margins. Long-term follow-up and careful monitoring are essential due to its high tendency of local recurrence in spite of wide excision of the tumor. Adjuvant antihormonal therapy yields promising results for preventing recurrence.

Aggressive Angiomyxoma

2012 ◽  
Vol 136 (2) ◽  
pp. 217-221 ◽  
Author(s):  
Brian J. Sutton ◽  
Jennifer Laudadio
Keyword(s):  
Local Recurrence ◽  
Progesterone Receptors ◽  
Chromosomal Translocation ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Gonadotropin Releasing Hormone ◽  
Aggressive Angiomyxoma ◽  
Estrogen And Progesterone Receptors ◽  
Myxoid Stroma ◽  
Emerging Therapy

Aggressive angiomyxoma is a rare mesenchymal tumor that most commonly arises in the vulvovaginal region, perineum, and pelvis of women. The term aggressive emphasizes the often infiltrative nature of the tumor and its frequent association with local recurrence. Patients often present with nonspecific symptoms which are frequently misdiagnosed with more common entities, such as a Bartholin cyst, lipoma, or hernia. Histologic examination reveals a hypocellular and highly vascular tumor with a myxoid stroma containing cytologically bland stellate or spindled cells. The tumor cells are characteristically positive for estrogen and progesterone receptors, suggesting a hormonal role in the development of the tumor. Chromosomal translocation of the 12q13-15 band involving the HMGA2 gene has been described. Surgical excision is the treatment of choice, although treatment with gonadotropin-releasing hormone agonists is an emerging therapy. Metastases are exceedingly rare, and overall, the prognosis is good.

scholarly journals Liposarcoma of mesorectum presenting as chronic intestinal obstruction: a rare case

2018 ◽  
Vol 5 (10) ◽  
pp. 3437 ◽  
Author(s):  
Rajesh Goud E. ◽  
Muvva Sri Harsha ◽  
Jakkula Srikanth ◽  
Kanmathareddy Amulya
Keyword(s):  
Soft Tissue ◽  
Local Recurrence ◽  
Rare Case ◽  
Spindle Cell ◽  
Surgical Excision ◽  
Clear Cut ◽  
Complete Surgical Excision ◽  
Neoplastic Lesions ◽  
Cell Variant ◽  
Well Differentiated

The term ‘liposarcoma’ refers to a spectrum of neoplastic lesions that can be benign to malignant and likely to recur or metastasize. Liposarcoma is a common soft tissue sarcoma found in adults and occurs mostly in extremities especially thigh followed by retroperitoneum. Here we present a case of spindle cell variant of well differentiated liposarcoma of mesorectum and underwent Anterior resection for the same. The treatment of choice for liposarcomas of retroperitoneum remains debatable and there are no clear-cut guidelines available regarding the same. However, considering the higher rates of local recurrence we advise a complete surgical excision following anatomical principles.

Aggressive angiomyxoma of the ischioanal fossa in a post-menopausal woman

2021 ◽  
Vol 103 (2) ◽  
pp. e59-e64
Author(s):  
E Peterknecht ◽  
E Agerbak ◽  
AYY Mohamedahmed ◽  
S Stonelake ◽  
K Kulkarni ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Perianal Abscess ◽  
Surgical Excision ◽  
Reproductive Age ◽  
Ischiorectal Fossa ◽  
Menopausal Woman ◽  
Aggressive Angiomyxoma ◽  
Buttock Pain ◽  
Post Menopausal

Aggressive angiomyxoma is a rare mesenchymal tumour, primarily arising in the soft tissue of the pelvis and perineum in women of reproductive age. There is a paucity of evidence on optimal management because of the rarity of these tumours, but the consensus has been for surgical excision. We present the case of a 65-year-old woman who was admitted with left-sided buttock pain and initially diagnosed with a perianal abscess. She underwent examination under anaesthesia rectum with surgical excision of the lesion, subsequent histopathological and immunochemical analysis was suggestive of aggressive angiomyxoma. To complement our case report, we also present a literature review focusing on aggressive angiomyxoma in the ischioanal fossa (also known as the ischiorectal fossa) with only eight cases of primary aggressive angiomyxoma involving the ischioanal fossa documented to date. The primary aims of this case report and literature review are to familiarise clinicians with the clinical, histopathological and immunochemical features of these tumours, and to increase appreciation that despite the rarity of aggressive angiomyxoma, it might be considered in the differential diagnosis of ischioanal lesions.

Aggressive angiomyxoma of larynx: case report and literature review

2009 ◽  
Vol 124 (7) ◽  
pp. 793-795 ◽  
Author(s):  
D C Sylvester ◽  
S Kortequee ◽  
J W Moor ◽  
C J Woodhead ◽  
K A Maclennan
Keyword(s):  
Case Report ◽  
World Literature ◽  
Surgical Excision ◽  
Endoscopic Examination ◽  
Excision Biopsy ◽  
Aggressive Angiomyxoma ◽  
Recent Advances ◽  
Complete Surgical Excision ◽  
The World ◽  
History Of

AbstractObjective:We report the second known case of aggressive angiomyxoma of the larynx.Method:Case report and a review of the world literature concerning angiomyxoma of the larynx and recent advances in the immunohistochemical, cytogenic and clinical study of its female pelvic counterpart.Results:Aggressive angiomyxoma is a rare mesenchymal tumour originally thought only to occur in the female pelvis and peritoneum, or rarely in the male genital tract. A 47-year-old man presented with a one-month history of dysphonia. He was found to have a supraglottic mass on endoscopic examination, and underwent a laryngofissure approach excision biopsy and covering tracheostomy. Histological analysis showed a characteristic proliferation of spindle cells widely separated by loose, myxoid stroma with a prominent vascular component. Aggressive angiomyxoma was diagnosed.Conclusion:To our knowledge, this is the second report in the world literature of aggressive angiomyxoma of the larynx. Comparison with the female pelvic counterpart facilitates diagnosis, aided by recent advances, and suggests that complete surgical excision with a wide margin is the treatment of choice.

scholarly journals Radical excision of a massive vulvo: Vaginal mass

2016 ◽  
Author(s):  
J. Meena ◽  
A. Parthasarathy ◽  
R. Vatsa ◽  
N. Singh ◽  
S. Kumar ◽  
...  
Keyword(s):  
Condylomata Acuminata ◽  
Surgical Excision ◽  
Posterior Wall ◽  
Reproductive Age ◽  
Ischiorectal Fossa ◽  
Radical Excision ◽  
Aggressive Angiomyxoma ◽  
Diagnostic Features ◽  
Vaginal Mass

Background: Vulvo-vaginal masses has a varied presentation and causes. The most common differential diagnosis are Condylomata acuminata, Vulvular abscess, Vulvular/vaginal cysts, Vulval carcinoma, Vulval lipoma, Angiomyofibroblastoma and Aggressive Angiomyxoma. Surgical excision of the mass is the main method of treatment and the outcome differs with the histological diagnosis. We present a video of excision of a massive Vulvo vaginal mass in toto. Case: A 45 year old P3 L3 female, presented with complaint of mass in perineal area & discharge per vaginum for 2 years. The mass was growing progressively and reached the present size. On examination there was a 9 X 8 cm irregular firm to cystic mass, arising from posterior wall of vagina and protruding out of introitus with bossellated surface. The mass also extended into right ischiorectal fossa, 10 X 10 cm mass with cystic, smooth surface that was irreducible with no cough impulse. CECT abdomen and pelvis revealed a well-defined 12 X 10 X 8 cm mass in right perineum arising from right lower lateral vaginal wall with ischiorectal fossa extension. There was no extension into cervix, bladder or rectum. Biopsy taken from the mass was inconclusive. A wide local excision was done under general anesthesia wherein an ischiorectal and vaginal mass of size 30 X 10 cm with irregular margin was excised in toto. Histopathology was suggestive of Aggressive Angiomyxoma. The patient is under follow up. Discussion: Aggressive Angiomyxoma is a rare slow growing locally invasive mesenchymal tumor and has a substantial potential for recurrence. It is often misdiagnosed. Pre-operative diagnosis is difficult due to rarity of this entity and absence of diagnostic features, but it should be considered in case of masses in genital, perianal and pelvic region in a woman of reproductive age. Radical surgical excision is the first line of management. A long term follow up of the case is necessary and MRI is preferred method for detecting recurrences.

scholarly journals Vulval aggressive angiomyxoma – a rare entity

2021 ◽  
Vol 11 (4) ◽  
pp. 100-102
Author(s):  
Jayakar Thomas
Keyword(s):  
Surgical Excision ◽  
Reproductive Age ◽  
Soft Tissue Tumour ◽  
Aggressive Angiomyxoma ◽  
Age Group ◽  
Rare Entity ◽  
Women Of Reproductive Age ◽  
Tissue Tumour ◽  
The Right ◽  
Reproductive Age Group

Aggressive Angiomyxoma is a very rare, distinctive, locally invasive soft tissue tumour, that occurs most commonly in the perineum, pelvis, vulva and vagina. It is seen mostly in women of reproductive age group. It has a tendency for recurrence locally, treatment being surgical excision. We hereby describe a case of 38-year-old patient with a pedunculated growth on the right labium majora.

Aggressive angiomyxoma of vagina: a rare entity

2017 ◽  
Vol 6 (12) ◽  
pp. 5654
Author(s):  
Ruby Bhatia ◽  
Manjit K. Mohi ◽  
Anju Gupta ◽  
Shalini Singh
Keyword(s):  
Surgical Excision ◽  
Vaginal Wall ◽  
Reproductive Age ◽  
Aggressive Angiomyxoma ◽  
Rare Entity ◽  
Diagnostic Features ◽  
Retrospective Diagnosis ◽  
Long Term Follow Up ◽  
Histological Confirmation

Aggressive angiomyxoma a soft tissue tumor arising in the pelvis and perineal regions of women in reproductive age group is a rare entity. It is slow growing locally aggressive myxoid mesenchymal tumor, with a marked tendency to local recurrence. Preoperative clinical diagnosis is usually difficult due to absence of diagnostic features as well as rarity of the disease. We describe a case of aggressive angiomyxoma of vagina in a 47-year-old para 4 woman with multiple fibromyoma (upto 22-week size of pregnant uterus) with 10*10 cms posterior vaginal cyst. Total abdominal hystrectomy with surgical excision of vaginal wall cyst done. A retrospective diagnosis-Aggressive Angiomyxoma of the vagina was made after histological confirmation. Surgical excision with wide margins and long term follow up remains treatment of choice.

scholarly journals Sinonasal Glomangiopericytoma: A Case Report and Literature Review

2019 ◽  
Vol 18 (3) ◽  
pp. 651-655
Author(s):  
Hyun Jin Min ◽  
Kyung Soo Kim
Keyword(s):  
Clinical Symptoms ◽  
Case Reports ◽  
Medical Science ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Recent Experience ◽  
Common Symptom ◽  
Complete Surgical Excision ◽  
Frequent Site ◽  
Ct Finding

Glomangiopericytoma is a rare vascular tumor arising from the pericytes surrounding capillaries, and accounts for less than 0.5% of all sinonasal tumors. The aim of this study is to describe our recent experience of sinonasal glomangiopericytoma and thoroughly review our collected data on the basis of age/sex, location, associated diseases, clinical symptoms, endoscopic findings, image findings, pathology, and treatment. We found 21 articles (19 case reports and 2 review articles) relevant to our search since 2005. The mean age was 58.05 years, ranging from 19 years to 86 years with a female to male ratio of 3:1 (15:5). The most frequent site of origin was the nasal septum followed by the paranasal sinuses. The most common symptom was nasal obstruction, followed by epistaxis, headache, facial pain or pressure, and anosmia in decreasing order. Computed tomography was the most common imaging technique used to evaluate sinonasal glomangiopericytoma which the most common mentioned CT finding was soft tissue density mass with enhancement. The most common treatment modality was complete surgical excision through transnasal endoscopic surgery. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.651-655

Vulvar soft tissue tumors

2004 ◽  
Vol 14 (1) ◽  
pp. 94-99
Author(s):  
K. A. Behranwala ◽  
B. Latifaj ◽  
P. Blake ◽  
D. P. J. Barton ◽  
J. H. Shepherd ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Local Recurrence ◽  
Surgical Excision ◽  
Primary Treatment ◽  
Soft Tissue Tumors ◽  
Soft Tissue Neoplasms ◽  
Low Grade ◽  
Aggressive Angiomyxoma ◽  
Royal Marsden Hospital ◽  
Histologic Types

ObjectiveTo report our incidence of soft tissue tumors at this site and to discuss various prognostic factors.MethodsAll patients with a diagnosis of vulvar soft tissue neoplasms were studied from a prospective database at the Royal Marsden Hospital between January 1985 and July 2001.ResultsSeventeen vulvar soft tissue neoplasms (11 malignant and six benign) were treated during this period. Leiomyosarcoma (n = 5) and aggressive angiomyxoma (n = 4) were the most frequent histologic types. According to the grade, there were four G3, three G2, three G1 and could not be assessed in one patient. Local recurrence occurred in six patients with sarcoma (three with high grade and one each with intermediate, low, and undetermined grade). In this group, five patients had negative microscopic margins and one patient had positive microscopic margins on excision. All three women with low-grade sarcomas are alive without evidence of disease. Three patients with aggressive angiomyxoma also had a local recurrence.ConclusionSurgical excision is the primary treatment where possible. The grade of the tumor is an important predictor for local recurrence and outcome. Aggressive angiomyxoma is a local problem. Leiomyosarcoma and aggressive angiomyxoma are the most frequent histologic types.

Infantile (desmoid-type) fibromatosis of the parotid gland

1997 ◽  
Vol 111 (7) ◽  
pp. 669-670 ◽  
Author(s):  
Ramesh Chandran Ramanathan ◽  
J. Meirion Thomas
Keyword(s):  
Local Recurrence ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Clinical Features ◽  
Surgical Excision ◽  
High Rate ◽  
Cytological Evidence ◽  
Deep Lobe ◽  
Complete Surgical Excision ◽  
Infancy And Childhood

AbstractInfantile fibromatosis, one of the fibrous tumours of infancy and childhood, is a fibroproliferative lesion characterized by aggressive local invasion without any tendency to metastasize, the absence of cytological evidence of malignancy and a high rate of local recurrence when incompletely excised. We report a case of infantile (desmoid-type) fibomatosis in a seven-year-old girl arising from the deep lobe of the parotid gland that was treated by complete surgical excision with preservation of the facial nerve. The clinical features, pathology and treatment are briefly discussed.

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