scholarly journals Backside Wear Analysis of Retrieved Acetabular Liners with a Press-Fit Locking Mechanism in Comparison to Wear Simulation In Vitro

2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Ana Laura Puente Reyna ◽  
Marcus Jäger ◽  
Thilo Floerkemeier ◽  
Sven Frecher ◽  
Karl-Stefan Delank ◽  
...  
Keyword(s):  
Acetabular Cup ◽  
Wear Process ◽  
Press Fit ◽  
Locking Mechanism ◽  
Inner Surface ◽  
Backside Wear ◽  
And Behavior ◽  
Wear Modes

Backside wear due to micromotion and poor conformity between the liner and its titanium alloy shell may contribute to the high rates of retroacetabular osteolysis and consequent aseptic loosening. The purpose of our study was to understand the wear process on the backside of polyethylene liners from two acetabular cup systems, whose locking mechanism is based on a press-fit cone in combination with a rough titanium conical inner surface on the fixation area. A direct comparison between in vitro wear simulator tests (equivalent to 3 years of use) and retrieved liners (average 13.1 months in situ) was done in order to evaluate the backside wear characteristics and behavior of these systems. Similar wear scores between in vitro tested and retrieved liners were observed. The results showed that this locking mechanism did not significantly produce wear marks at the backside of the polyethylene liners due to micromotion. In all the analyzed liners, the most common wear modes observed were small scratches at the cranial fixation zone directly below the rough titanium inner surface of the shell. It was concluded that most of the wear marks were produced during the insertion and removal of the liner, rather than during its time in situ.

scholarly journals ARTICULATION AND BACKSIDE WEAR ANALYSIS AFTER LONG-TERM IN VITRO WEAR SIMULATION OF VITAMIN E STABILIZED POLYETHYLENE ACETABULAR LINERS WITH A PRESS-FIT LOCKING MECHANISM

2018 ◽  
Vol 24 (2) ◽  
pp. 29-40 ◽  
Author(s):  
A. L. Puente Reyna ◽  
M. Holderied ◽  
M. Jäger ◽  
C. Schilling ◽  
T. M. Grupp
Keyword(s):  
Vitamin E ◽  
Axial Load ◽  
Convex Surface ◽  
Wear Simulation ◽  
Press Fit ◽  
Locking Mechanism ◽  
Backside Wear ◽  
Measuring Machine ◽  
Fixation Area

A previous retrieval study analyzed the backside wear of short-term implanted liners against in vitro tested liners of similar life in service and showed comparable results among both groups, with no significant backside wear due to micro-motion.The purpose — to obtain a picture of the overall wear (articulation and backside surfaces) of 0.1% vitamin e blended polyethylene liners, with a locking mechanism based on a press-fit cone in combination with a rough titanium conical inner surface in the fixation area, under a 20 million cycles hip wear simulation.Materials and Methods. A semi-quantitative method was used in order to assess the damage on the backside of the liners and a 3d measuring machine to assess the creep and wear at the articulation surface.Results. The total average backside wear score was 22.00±2.59 from a maximum total score of 147 after 5 million cycles (mc), increased to 31.92±5.57 after 10 mc, but showed no further increment after 15 and 20 mc. The reference liners (subjected only to axial load) showed similar wear scores and modes as the liners under wear simulation (axial load and movement). Small scratches produced during insertion and removal were clearly seen at the rim (fixation) area and no considerable abrasion was observed. The machining marks on the convex surface were always visible. Regarding the articulation surface, a steady state wear rate of 7 µm/year was measured.Conlusion. These results determined that most of the backside wear produced on the liners occurred during their insertion and removal rather than during their life in service. Moreover, the wear at the articulation surface was similar to that seen in vivo at short- and mid-term on highly cross-linked polyethylene liners with and without vitamin e content.

Failure of an Uncemented Press-Fit Acetabular Cup in Primary Total Hip Arthroplasty

2002 ◽  
Vol 12 (4) ◽  
pp. 371-377 ◽  
Author(s):  
N. Rama Mohan ◽  
P. Grigoris ◽  
D.L. Hamblen
Keyword(s):  
Femoral Stem ◽  
Acetabular Cup ◽  
Total Hip ◽  
Press Fit ◽  
Total Hip Replacements ◽  
Locking Mechanism ◽  
Hip Replacements ◽  
The Mean ◽  
Open Position ◽  
Primary Total Hip Arthroplasty

We reviewed fifteen primary total hip replacements performed using the uncemented, non-porous coated press-fit AcSys Shearer Cup. A modular titanium straight femoral stem with a 32mm head was used in all cases. The mean age of the group containing five males and 10 females was 66 years. Eight cups have been revised for aseptic loosening at a mean of seven years and the remaining four cups are radiologically loose. At revision surgery none of the cups showed any evidence of bony ingrowth. Our 10-year results with this cup indicate an unacceptably high failure rate of 80%. Absence of bony ingrowth and the lack of a secure locking mechanism between the polyethylene liner and the metal shell are the most important causes of failure. The use of a 32mm diameter head and implantation of the cup in an open position contributed to this failure. Even though this cup is no longer manufactured, our experience suggests that all non-porous coated cups should be closely followed up.

scholarly journals Comparison of Test Setups for the Experimental Evaluation of the Primary Fixation Stability of Acetabular Cups

Materials ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 3982
Author(s):  
Christian Schulze ◽  
Danny Vogel ◽  
Sina Mallow ◽  
Rainer Bader
Keyword(s):  
Test Methods ◽  
Load Test ◽  
Test Method ◽  
Artificial Bone ◽  
Acetabular Cup ◽  
Acetabular Bone ◽  
Press Fit ◽  
Orthopedic Surgeons ◽  
Fixation Stability

Sufficient primary fixation stability is the basis for the osseointegration of cementless acetabular cups. Several test methods have been established for determining the tilting moment of acetabular press-fit cups, which is a measure for their primary fixation stability. The central aim of this experimental study was to show the differences between the commonly used lever-out test method (Method 1) and the edge-load test method (Method 2) in which the cup insert is axially loaded (1 kN) during the tilting process with respect to the parameters, tilting moment, and interface stiffness. Therefore, using a biomechanical cup block model, a press-fit cup design with a macro-structured surface was pushed into three cavity types (intact, moderate superior defect, and two-point-pinching cavity) made of 15 pcf and 30 pcf polyurethane foam blocks (n = 3 per cavity and foam density combination), respectively. Subsequently, the acetabular cup was disassembled from the three artificial bone cavities using the lever-out and the edge-load test method. Tilting moments determined with Method 1 ranged from 2.72 ± 0.29 Nm to 49.08 ± 1.50 Nm, and with Method 2, they ranged from 41.40 ± 1.05 Nm to 112.86 ± 5.29 Nm. In Method 2, larger areas of abrasion were observed in the artificial bone cavity compared to Method 1. This indicates increased shear forces at the implant–bone interface in the former method. In conclusion, Method 1 simulates the technique used by orthopedic surgeons to assess the correct fit of the trial cup, while Method 2 simulates the tilting of the cup in the acetabular bone cavity under in situ loading with the hip resultant force.

scholarly journals Dependence of the primary stability of cementless acetabular cup implants on the biomechanical environment

2019 ◽  
Vol 233 (12) ◽  
pp. 1237-1249
Author(s):  
Maria Letizia Raffa ◽  
Vu-Hieu Nguyen ◽  
Elisabeth Tabor ◽  
Katharina Immel ◽  
Victor Housset ◽  
...  
Keyword(s):  
Nonlinear Dependence ◽  
Reference Configuration ◽  
Patient Specific ◽  
In Vitro Test ◽  
Acetabular Cup ◽  
Press Fit ◽  
Biomechanical Behavior ◽  
Pull Out ◽  
Optimal Value

Biomechanical phenomena occurring at the bone–implant interface during the press-fit insertion of acetabular cup implants are still poorly understood. This article presents a nonlinear geometrical two-dimensional axisymmetric finite element model aiming at describing the biomechanical behavior of the acetabular cup implant as a function of the bone Young’s modulus Eb, the diametric interference fit ( IF), and the friction coefficient µ. The numerical model was compared with experimental results obtained from an in vitro test, which allows to determine a reference configuration with the parameter set: μ*  = 0.3, [Formula: see text], and IF*  = 1 mm for which the maximal contact pressure tN = 10.7 MPa was found to be localized at the peri-equatorial rim of the acetabular cavity. Parametric studies were carried out, showing that an optimal value of the pull-out force can be defined as a function of μ, Eb, and IF. For the reference configuration, the optimal pull-out force is obtained for μ  = 0.6 (respectively, Eb = 0.35 GPa and IF = 1.4 mm). For relatively low value of µ ( µ < 0.2), the optimal value of IF linearly increases as a function of µ independently of Eb, while for µ > 0.2, the optimal value of IF has a nonlinear dependence on µ and decreases as a function of Eb. The results can be used to help surgeons determine the optimal value of IF in a patient specific manner.

In Vitro Evaluation of the Acetabular Cup Primary Stability by Impact Analysis

2015 ◽  
Vol 137 (3) ◽  
Author(s):  
Adrien Michel ◽  
Romain Bosc ◽  
Romain Vayron ◽  
Guillaume Haiat
Keyword(s):  
Impact Analysis ◽  
Primary Stability ◽  
Bovine Bone ◽  
Acetabular Cup ◽  
Hip Prostheses ◽  
Press Fit ◽  
The Press ◽  
Force Signal ◽  
The Impact

The implant primary stability of the acetabular cup (AC) is an important parameter for the surgical success of press-fit procedures used for the insertion of cementless hip prostheses. In previous studies by our group (Mathieu, V., Michel, A., Lachaniette, C. H. F., Poignard, A., Hernigou, P., Allain, J., and Haiat, G., 2013, “Variation of the Impact Duration During the in vitro Insertion of Acetabular Cup Implants,” Med. Eng. Phys., 35(11), pp. 1558–1563) and (Michel, A., Bosc, R., Mathieu, V., Hernigou, P., and Haiat, G., 2014, “Monitoring the Press-Fit Insertion of an Acetabular Cup by Impact Measurements: Influence of Bone Abrasion,” Proc. Inst. Mech. Eng., Part H, 228(10), pp. 1027–1034), the impact momentum and duration were shown to carry information on the press-fit insertion of the AC within bone tissue. The aim of the present study is to relate the impact momentum recorded during the AC insertion to the AC biomechanical primary stability. The experimental protocol consisted in testing 13 bovine bone samples that underwent successively series of 15 reproducible mass falls impacts (5 kg, 5 cm) followed by tangential stability testing. Each bone sample was tested with different hole sizes in order to obtain different stability configurations. The impact momentum and the tangential primary stability reach a maximum value for an interference fit equal to around 1 mm. Moreover, a correlation between the impact momentum and the stability was obtained with all samples and all configuration (R2 = 0.65). The implant primary stability can be assessed through the measurement of the impact force signal analysis. This study opens new paths for the development of a medical device which could be used as a decision support system to assist the surgeon during the insertion of the AC implant.

Correlated Studies of Cellular Interactions Using TEM, Freeze Etching, and SEM

1974 ◽  
Vol 32 ◽  
pp. 320-321
Author(s):  
J. P. Revel
Keyword(s):  
Developmental Stages ◽  
Three Dimensional ◽  
Cell Movement ◽  
Cellular Interactions ◽  
Serial Sections ◽  
Cell Sheets ◽  
Freeze Etching ◽  
Early Developmental

Movement of individual cells or of cell sheets and complex patterns of folding play a prominent role in the early developmental stages of the embryo. Our understanding of these processes is based on three- dimensional reconstructions laboriously prepared from serial sections, and from autoradiographic and other studies. Many concepts have also evolved from extrapolation of investigations of cell movement carried out in vitro. The scanning electron microscope now allows us to examine some of these events in situ. It is possible to prepare dissections of embryos and even of tissues of adult animals which reveal existing relationships between various structures more readily than used to be possible vithout an SEM.

In vitro and in vivo polysaccharides assembly: ultrastructural and cytochemical study of growing plant cell wall components.

1978 ◽  
Vol 36 (2) ◽  
pp. 434-435
Author(s):  
D. Reis ◽  
B. Vian ◽  
J. C. Roland
Keyword(s):  
Cell Wall ◽  
Self Assembly ◽  
Plant Cell Wall ◽  
Higher Plants ◽  
Three Dimensional ◽  
Cytochemical Study ◽  
Wall Components

Wall morphogenesis in higher plants is a problem still open to controversy. Until now the possibility of a transmembrane control and the involvement of microtubules were mostly envisaged. Self-assembly processes have been observed in the case of walls of Chlamydomonas and bacteria. Spontaneous gelling interactions between xanthan and galactomannan from Ceratonia have been analyzed very recently. The present work provides indications that some processes of spontaneous aggregation could occur in higher plants during the formation and expansion of cell wall.Observations were performed on hypocotyl of mung bean (Phaseolus aureus) for which growth characteristics and wall composition have been previously defined.In situ, the walls of actively growing cells (primary walls) show an ordered three-dimensional organization (fig. 1). The wall is typically polylamellate with multifibrillar layers alternately transverse and longitudinal. Between these layers intermediate strata exist in which the orientation of microfibrils progressively rotates. Thus a progressive change in the morphogenetic activity occurs.

In Situ Localization of PPAR Gamma and Uncoupling Protein in Mouse Embryo Sections Using Digoxigenin-Labeled Riboprobes

1996 ◽  
Vol 54 ◽  
pp. 32-33
Author(s):  
C. Jennermann ◽  
S. A. Kliewer ◽  
D. C. Morris
Keyword(s):  
Alkaline Phosphatase ◽  
Room Temperature ◽  
Uncoupling Protein ◽  
Ppar Gamma ◽  
Nuclear Hormone Receptor ◽  
Full Length ◽  
Northern Analysis ◽  
Peroxisome Proliferator

Peroxisome proliferator-activated receptor gamma (PPARg) is a member of the nuclear hormone receptor superfamily and has been shown in vitro to regulate genes involved in lipid metabolism and adipocyte differentiation. By Northern analysis, we and other researchers have shown that expression of this receptor predominates in adipose tissue in adult mice, and appears first in whole-embryo mRNA at 13.5 days postconception. In situ hybridization was used to find out in which developing tissues PPARg is specifically expressed.Digoxigenin-labeled riboprobes were generated using the Genius™ 4 RNA Labeling Kit from Boehringer Mannheim. Full length PPAR gamma, obtained by PCR from mouse liver cDNA, was inserted into pBluescript SK and used as template for the transcription reaction. Probes of average size 200 base pairs were made by partial alkaline hydrolysis of the full length transcripts. The in situ hybridization assays were performed as described previously with some modifications. Frozen sections (10 μm thick) of day 18 mouse embryos were cut, fixed with 4% paraformaldehyde and acetylated with 0.25% acetic anhydride in 1.0M triethanolamine buffer. The sections were incubated for 2 hours at room temperature in pre-hybridization buffer, and were then hybridized with a probe concentration of 200μg per ml at 70° C, overnight in a humidified chamber. Following stringent washes in SSC buffers, the immunological detection steps were performed at room temperature. The alkaline phosphatase labeled, anti-digoxigenin antibody and detection buffers were purchased from Boehringer Mannheim. The sections were treated with a blocking buffer for one hour and incubated with antibody solution at a 1:5000 dilution for 2 hours, both at room temperature. Colored precipitate was formed by exposure to the alkaline phosphatase substrate nitrobluetetrazoliumchloride/ bromo-chloroindlylphosphate.

CONSERVATION OF RARE SPECIES PLANTS AND LICHENS IN SITU WITH PLANNED ANTHROPOGENIC ACTIVITIES: BASIC APPROACHES AND IMPLEMENTATION PRINCIPLES

2018 ◽  
Vol 12 (7-8) ◽  
pp. 38-45
Author(s):  
A. N. EFREMOV ◽  
N. V. PLIKINA ◽  
T. ABELI
Keyword(s):  
Rare Species ◽  
Technology Implementation ◽  
Technology Development ◽  
Anthropogenic Activities ◽  
Natural Habitat ◽  
Local Population ◽  
Main Stage ◽  
Social Risks

Rare species are most vulnerable to man-made impacts, due to their biological characteristics or natural resource management. As a rule, the economic impact is associated with the destruction and damage of individual organisms, the destruction or alienation of habitats. Unfortunately, the conservation of habitat integrity is an important protection strategy, which is not always achievable in the implementation of industrial and infrastructural projects. The aim of the publication is to summarize the experience in the field of protection of rare species in the natural habitat (in situ), to evaluate and analyze the possibility of using existing methods in design and survey activities. In this regard, the main methodological approaches to the protection of rare species in the natural habitat (in situ) during the proposed economic activity were reflected. The algorithm suggested by the authors for implementing the in situ project should include a preparatory stage (initial data collection, preliminary risk assessments, technology development, obtaining permitting documentation), the main stage, the content of which is determined by the selected technology and a long monitoring stage, which makes it possible to assess the effectiveness of the taken measures. Among the main risks of in situ technology implementation, the following can be noted: the limited resources of the population that do not allow for the implementation of the procedure without prior reproduction of individuals in situ (in vitro); limited knowledge of the biology of the species; the possibility of invasion; the possibility of crossing for closely related species that сo-exist in the same habitat; social risks and consequences, target species or population may be important for the local population; financial risks during the recovery of the population. The available experience makes it possible to consider the approach to the conservation of rare species in situ as the best available technology that contributes to reducing negative environmental risks.

Sign in / Sign up

Export Citation Format

Share Document