scholarly journals Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Wenwen He ◽  
Xiangjia Zhu ◽  
Don Wolff ◽  
Zhennan Zhao ◽  
Xinghuai Sun ◽  
...  

Purpose.To evaluate the anterior chamber volume in cataract patients with Swept-Source Optical Coherence Tomography (SS-OCT) and its influencing factors.Methods.Anterior chamber volume of 92 cataract patients was evaluated with SS-OCT in this cross-sectional study. Univariate analyses and multiple linear regression were used to investigate gender, age, operated eye, posterior vitreous detachment, lens opacity grading, and axial length (AXL) related variables capable of influencing the ACV.Results.The average ACV was 139.80 ± 38.21 mm3(range 59.41 to 254.09 mm3). The average ACV was significantly larger in male patients than in female patients (P=0.001). ACV was negatively correlated with age and LOCS III cortical (C) grading of the lens (Pearson’s correlation analysis,r=-0.443,P<0.001, and Spearman’s correlation analysis,ρ=-0.450,P<0.001). ACV was also increased with AXL (Pearson’s correlation analysis,r=0.552,P<0.001). Multiple linear regression showed that, with all of the covariates entered into the model, gender (P=0.002), age (P=0.015), LOCS III C grade (P=0.043), and AXL (P=0.001) were still associated with ACV (F=10.252  P<0.001  R2=0.498).Conclusion.With SS-OCT, we found that, in healthy cataract patients, ACV varied significantly among different subjects. Influencing factors that contribute to reduced ACV were female gender, increased age, LOCS III C grade, and shorter AXL.

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Lan Yang ◽  
Bingbing Zhang ◽  
Xiaoxing Kong ◽  
Weifang Zhou ◽  
Jianmei Tian ◽  
...  

Background: The Coronavirus disease 2019 (COVID-19) pandemic has posed a severe threat to international health and the economy. Clinicians, the main staff involved in fighting against the pandemic, are under great pressure. However, relevant mental stress studies are lacking at present. Objectives: This study aimed to explore the mental stress level and its influencing factors among Chinese pediatricians under the outbreak of COVID-19, aiming to provide a certain theoretical basis for relevant psychological intervention among medical staff. Methods: In this cross-sectional study, 352 in-service pediatricians were selected from nine hospitals in Jiangsu province, China, in February 2020. The online survey was performed to collect general information. Meanwhile, the Perceived Stress Scale (PSS-10), Self-rating Anxiety Scale (SAS), and Pittsburgh Sleep Quality Index (PSQI) scale were employed for assessment. Afterward, the stress level and influencing factors among pediatricians were analyzed through descriptive analysis, one-way analysis of variance (ANOVA), correlation analysis, and multiple linear regression analysis. Results: The mean score of PSS-10 showed moderate stress on the whole. Pediatricians from outpatient and emergency departments had significantly higher perceived stress than those from other departments. The perceived stress was significantly associated with age, educational level, professional title, work experience, and physical condition. Stepwise multiple linear regression showed that age, professional title, and physical condition had a linear relationship with the individual’s perceived stress. Besides, Pearson correlation analysis indicated that perceived stress was associated with anxiety level and sleep quality. Conclusions: Under the outbreak of COVID-19, pediatricians suffer from relatively high levels of mental stress. The influencing factors include education, age, professional title, work experience, and physical condition. Typically, the anxiety level and sleep quality are correlated with the mental stress among pediatricians.


2021 ◽  
Vol 2021 (3) ◽  
Author(s):  
Esther Papamlichael ◽  
Abison Logeswaran ◽  
Vasilios P Papastefanou ◽  
Martin Watson ◽  
Andrew Coombes

Abstract We describe a case of bilateral spontaneous corneal perforation secondary to pellucid marginal degeneration and present the associated swept-source anterior segment optical coherence tomography (SS-ASOCT) findings and management principles used. A 47-year-old woman presented with ocular pain, redness, foreign body sensation and clear discharge in the right eye in 2017 and with very similar symptoms in 2019 in the left eye. Clinically she had a corneal perforation at the inferior cornea with associated loss of anterior chamber volume. Corneal topography demonstrated peripheral thinning and steepening in the contralateral eye. ASOCT images revealed full-thickness perforation, iridocorneal touch and iris stranding. The patient was managed with a combination of contact bandaging and corneal gluing. SS-ASOCT is a useful adjunctive tool in the clinical assessment and evaluation of spontaneous corneal perforation. Alongside the clinical evaluation, it can be used to monitor the clinical response.


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Shuning Li ◽  
Jing Jiang ◽  
Yiquan Yang ◽  
Gewei Wu ◽  
Shi-Ming Li ◽  
...  

Background. To determine the range of pupil size that has the largest iris volume in normal eyes. Methods. 31 healthy adult Chinese volunteers underwent swept-source anterior segment OCT examination in both eyes. Pilocarpine 1% was instilled in a randomly selected eye (eye with induced miosis (ME)) of each participant to obtain iris volume (IV) measurements over a range of pupil sizes. OCT was performed prior to and one hour after pilocarpine in both ME and fellow eye (FE). Iris volume (IV), anterior chamber volume (ACV), anterior chamber depth (ACD), and pupil size (PS) were recorded. A scatter plot was used to depict the association between each pupil size and IV. Results. The pupillary sizes for which IV was recorded in ME and FE ranged from 1.161 mm to 6.665 mm. The mean IV increased with miosis in both ME and FE; in 13 eyes, IV decreased with a decrease in pupillary size. PS between 3.812 and 6.665 mm was associated with an increase in IV, while PS between 3.159 and 5.54 mm was associated with a decrease. The relationship between PS and IV was in the shape of a downward parabola and was modeled using a quadratic equation (y = −1.3121x2 + 8.8429x + 16.423, R2 = 0.26886). The largest IV occurred at PS between 3 and 4 mm. Conclusions. The relationship between PS and IV in this study was in the shape of a downward parabola. The largest IV was recorded at a pupillary size between 3 and 4 mm. This trial is registered with ChiCTR-ROC-17013572.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Giedre Pakuliene ◽  
Kirilas Zimarinas ◽  
Irena Nedzelskiene ◽  
Brent Siesky ◽  
Loreta Kuzmiene ◽  
...  

Abstract Background Anterior chamber angle anatomy in perspective of ocular biometry may be the key element to intraocular pressure (IOP) reduction, especially in glaucoma patients. We aim to investigate anterior chamber angle and biometrical data prior to cataract surgery in patients with and without glaucoma comorbidity. Materials and methods This prospective comparative case-control study included 62 subjects (38 with cataract only and 24 with cataract and glaucoma). A full ophthalmic examination including, Goldmann applanation tonometry, anterior chamber swept source optical coherence tomography (DRI OCT Triton plus (Ver.10.13)) and swept source optical biometry (IOL Master 700 v1.7) was performed on all participants. Results We found that ocular biometry parameters and anterior chamber parameters were not significantly different among groups. However, when we added cut-off values for narrow angles, we found that glaucoma group tended to have more narrow angles than control group. IOP was higher in glaucoma group despite all glaucoma patients having medically controlled IOP. In all subjects, anterior chamber parameters correlated well with lens position (LP), but less with relative lens position, while LP cut-off value of 5.1 mm could be used for predicting narrow anterior chamber angle parameters. Conclusions Cataract patients tend to develop narrow anterior chamber angles. Anterior chamber angle parameters have a positive moderate to strong relationship with lens position. LP may be used predicting narrow angles.


2018 ◽  
Vol 16 (2) ◽  
pp. 86-94
Author(s):  
Vijaya Anandan ◽  
Rekha Srinivasan ◽  
Rashima Asokan ◽  
Ronnie George

Aim: To compare the anterior chamber volume measurements obtained with Pentacam and derived from anterior segment optical coherence tomography. Design: Cross-sectional study. Methods: We included normal subjects who underwent a comprehensive eye examination including refraction, keratometry, Goldmann applanation tonometry, gonioscopy, anterior segment optical coherence tomography (AS-OCT) (Carl Zeiss Meditec Inc.; Dublin, CA, USA) and Pentacam (Oculus Inc.; Lynnwood, WA, USA). Fifty scans were selected for Pentacam and 12 images were selected for calculation of anterior chamber volume. Only the right eye was considered for analysis. Results: One-hundred and nineteen eyes of 119 subjects were included for analysis. The mean age of the subjects was 42.58 ± 13.15 years, of which 74 were female and 45 were male. The mean anterior chamber volume measured using AS-OCT was 119.17 ± 26.56 mm3 and with Pentacam was 131.29 ± 34.26 mm3. The comparison of means between the two modalities was statistically significant (t = -8.857, Mean Difference (MD) = 12.11, 95% CI: (4.29, 19.95), p = 0.003). Bland-Altman plot showed poor agreement between the chamber volume measurements obtained by Pentacam and AS-OCT with MD of 12.1 mm3 (95 % CI: 41.4 to -17.1) and intra-class correlation between the two instruments was 0.94 (95% CI: 0.91, 0.96) (p < 0.0001). Conclusion: The anterior chamber volume can be measured using Pentacam as well as AS-OCT since these measurements were reliable. However, these measurements were not interchangeable due to poor levels of agreement.


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