scholarly journals Relationship between FEV1 and Cardiovascular Risk Factors in General Population without Airflow Limitation

2016 ◽  
Vol 2016 ◽  
pp. 1-7
Author(s):  
Jeong Hyeon Lee ◽  
Yun-Seong Kang ◽  
Yun-Jeong Jeong ◽  
Young-Soon Yoon ◽  
Won Gun Kwack ◽  
...  

Purpose. We aimed to determine the value of lung function measurement for predicting cardiovascular (CV) disease by evaluating the association between FEV1 (%) and CV risk factors in general population. Materials and Methods. This was a cross-sectional, retrospective study of subjects above 18 years of age who underwent health examinations. The relationship between FEV1 (%) and presence of carotid plaque and thickened carotid IMT (≥0.8 mm) was analyzed by multiple logistic regression, and the relationship between FEV1 (%) and PWV (%), and serum uric acid was analyzed by multiple linear regression. Various factors were adjusted by using Model 1 and Model 2. Results. 1,003 subjects were enrolled in this study and 96.7% (n=970) of the subjects were men. In both models, the odds ratio of the presence of carotid plaque and thickened carotid IMT had no consistent trend and statistical significance. In the analysis of the PWV (%) and uric acid, there was no significant relationship with FEV1 (%) in both models. Conclusion. FEV1 had no significant relationship with CV risk factors. The result suggests that FEV1 may have no association with CV risk factors or may be insensitive to detecting the association in general population without airflow limitation.

2021 ◽  
Vol 2 (1) ◽  
pp. 23
Author(s):  
Putri Ayu Anjani ◽  
Khairizka Citra Palupi ◽  
Mertien Sa’pang ◽  
Dudung Angkasa ◽  
Vitria Melani

Constipation marked by feces hard one, dry, and difficult issued. About 73.9% pregnant women experience constipation. Increase in the hormone progesterone for pregnant women resulted in drop motility gastrointestinal tract. Constipation affects psychology and causes swelling of the rectum area.To determine the relationship between the level of fiber adequacy, to consumption of Fe tablets and depression and to see the combined risk factors for depression and adherence to consumption of Fe tablets with the incidence of constipation in pregnant women. Design this research is observational analytics with Cross Sectional design. The sample of pregnant women is 55 people with purposive sampling data collection technique. Taking data done with use questionnaire. Statistic test used the chi-square test. 58.2% of pregnant women experienced constipation; 92.7% insufficient fiber sufficiency level; 40.0% adhered to consuming Fe tablets; 55.4% experienced depression; 23.6% of depression was adherent. The results of the chi-square test showed that there was no significant relationship between the level of fiber adequacy and the incidence of constipation in pregnant women (p = 0.298) and a significant relationship with the incidence of constipation in pregnant women, namely consuming Fe tablets (p = 0.039; OR = 4.080), depression (p = 0.026; OR = 4.125), risk factors for the combination of depression and adherence to consumption of Fe tablets (p = 0.005).Compliance with Fe tablet consumption and depression can increase the risk of constipation in pregnant women by 4,080 times and 4,125 times.


Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Hossein Bahrami ◽  
Joao A Lima ◽  
Joseph F Polak ◽  
Gregory D Pearson ◽  
Kiang Liu ◽  
...  

Background: While increased carotid intima-media thickness (IMT) is considered an independent risk factor for cardiovascular disease (CVD), little is known about the relationship of aortic thickness (AWT) and aortic distensibility (AD) with CVD risk factors. We studied the association of these aortic parameters with other measures of subclinical CVD. Methods: The Multi-Ethnic Study of Atherosclerosis (MESA) includes 6,814 participants, aged 45– 85 years; white, African-American, Hispanic, and Chinese. AD and AWT were measured by MRI. Average and maximum AWT of the proximal descending thoracic aorta were used as two measures of AWT. AD was calculated as the difference in aortic cross-sectional area indexed by diastolic cross-sectional area and average pulse pressure. IMT of the common and internal carotid arteries were determined by high-resolution B-mode ultrasonography and LV mass was determined by MRI. Phantom-adjusted Agatston calcium score from CT images was used to define coronary artery calcification (CAC). Results: In univariable analyses, higher carotid IMT, ankle-brachial index (ABI) <0.9, CAC score, LV mass, and presence of coronary calcium were associated with lower AD and higher AWT (table ). However, in multivariable analyses, the only measures of subclinical CVD that had significant associations with both AD and AWT were LV mass and carotid IMT, while ABI was associated with only AWT. After adding age to the models, CAC score was no longer associated with either AD or AWT. The relationship between CAC score and AD varied by ethnicity; higher CAC score was associated with higher AD only in African Americans. Conclusions: AD and AWT are related to carotid IMT and LV mass, even after controlling for traditional risk factors. The associations of AD and AWT with CAC appears to be mainly due to their relationship with conventional risk factors, particularly age. Overall, AWT and AD may have closer relationship with LV mass than with subclinical atherosclerosis.


2019 ◽  
Vol 12 (1) ◽  
pp. 420-423
Author(s):  
Prapada Watcharanat ◽  
Prasong Tanpichai ◽  
Ravee Sajjasophon

Purpose: This research aims to study the relationship between perception of elderly’s health and health behaviors in Nakhon Nayok province, Thailand Methods: This research was a cross-sectional study. The questionnaire was used to collect the data. This research was conducted in Nakhon Nayok province. The sample size was 270 which applied Taro Yamane's formula at a significant level 0.05. The descriptive statistics was implemented to describe the variables by presenting the frequency, percentage, mean and standard deviation. Furthermore, multiple regression analysis was applied to analyze the relationship between perception of elderly’s health and health behaviors. The statistical significance was considered to reject Hypothesis-null at < 0.05. Results: From a total of 270 people, more than 58.22% of the elderly perceived that they had moderate health conditions. Most elderly had congenital diseases (62.2%). The multiple regression analysis results showed that health status perception and health status perception when compared to their cohort related significantly to health behavior. Conclusion: The government should support the elderly on participation, trust, engagement, and cultural concern of the people in the community, which can contribute to promoting the physical, mental and social condition of the elderly.


2013 ◽  
Vol 70 (11) ◽  
pp. 993-998 ◽  
Author(s):  
Djordje Milosevic ◽  
Janko Pasternak ◽  
Vladan Popovic ◽  
Dragan Nikolic ◽  
Pavle Milosevic ◽  
...  

Background/Aim. A certain percentage of patients with asymptomatic carotid stenosis have an unstable carotid plaque. For these patients it is possible to register by modern imaging methods the existence of lesions of the brain parenchyma - the silent brain infarction. These patients have a greater risk of ischemic stroke. The aim of this study was to analyze the connection between the morphology of atherosclerotic carotid plaque in patients with asymptomatic carotid stenosis and the manifestation of silent brain infarction, and to analyze the influence of risk factors for cardiovascular diseases on the occurrence of silent brain infarction and the morphology of carotid plaque. Methods. This retrospective study included patients who had been operated for high grade (> 70%) extracranial atherosclerotic carotid stenosis at the Clinic for Vascular and Transplantation Surgery of the Clinical Center of Vojvodina over a period of 5 years. The patients analyzed had no clinical manifestation of cerebrovascular insufficiency of the carotid artery territory up to the time of operation. The classification of carotid plaque morphology was carried out according to the Gray-Weale classification, after which all the types were subcategorized into two groups: stable and unstable. Brain lesions were verified using preoperative imaging of the brain parenchyma by magnetic resonance. We analyzed ipsilateral lesions of the size > or = 3 mm. Results. Out of a 201 patients 78% had stable plaque and 22% unstable one. Unstable plaque was prevalent in the male patients (male/female ratio = 24.8% : 17.8%), but without a statistically significant difference (p > 0.05). The risk factors (hypertension, nicotinism, hyperlipoproteinemia, and diabetes mellitus) showed no statistically significant impact on carotid plaque morphology and the occurrence of silent brain infarction. Silent brain infarction was detected in 30.8% of the patients. Unstable carotid plaque was found in a larger percentage of patients with silent brain infarction (36.4% : 29.3%) but without a significant statistical difference (p > 0.05). Conclusions. Even though silent brain infarction is more frequent in patients with unstable plaque of carotid bifurication, the difference is of no statistical significance. The effects of the number and type of risk factors bear no statistical significance on the incidence of morphological asymptomatic carotid plaque.


Author(s):  
Menglin Jiang ◽  
Dandan Gong ◽  
Yu Fan

AbstractElevated serum uric acid (SUA) levels may increase the risk of prehypertension. However, the findings from these studies remain conflicting. The objective of this study was to determine the relationship between SUA levels and risk of prehypertension by conducting a meta-analysis. We conducted a comprehensive literature search of PubMed, Embase, China National Knowledge Infrastructure, VIP, and the Wangfang database without language restrictions through May 2015. Observational studies assessing the relationship between SUA levels and prevalence of prehypertension were included. Pooled adjust odds ratio (OR) and corresponding 95% confidence intervals (CI) of prehypertension were calculated for the highest vs. lowest SUA levels. Prehypertension was defined as systolic blood pressure (BP) ranging from 120 to 139 mmHg or diastolic BP ranging from 80 to 89 mmHg. Eight cross-sectional studies with a total of 21,832 prehypertensive individuals were included. Meta-analysis showed that elevated SUA levels were associated with increased risk of prehypertension (OR: 1.84; 95% CI: 1.42–2.38) comparing the highest vs. lowest level of SUA levels. Subgroup analyses showed that elevated SUA levels significantly increased the risk of prehypertension among men (OR: 1.60; 95% CI: 1.12–2.21) and women (OR: 1.59; 95% CI: 1.17–2.16). Elevated SUA levels are positively associated with the risk of prehypertension in the general population. However, more well-designed longitudinal studies are needed before a definitive conclusion can be drawn due to the cross-sectional studies included are susceptible to bias.


2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1232.1-1232
Author(s):  
M. Di Battista ◽  
S. Barsotti ◽  
A. Della Rossa ◽  
M. Mosca

Background:Cardiovascular (CV) diseases, namely myocardial infarction and stroke, are not among the most known and frequent complications of systemic sclerosis (SSc), but there is growing evidence that SSc patients have a higher prevalence of CV diseases than the general population [1].Objectives:To compare two algorithms for CV risk estimation in a cohort of patients with SSc, finding any correlation with clinical characteristics of the disease.Methods:SSc patients without previous myocardial infarction or stroke were enrolled. Traditional CV risk factors, SSc-specific characteristics and ongoing therapies were assessed. Framingham and QRISK3 algorithms were then used to estimate the risk of develop a CV disease over the next 10 years.Results:Fifty-six SSc patients were enrolled. Framingham reported a median risk score of 9.6% (IQR 8.5), classifying 24 (42.9%) subjects at high risk, with a two-fold increase of the mean relative risk in comparison to general population. QRISK3 showed a median risk score of 15.8% (IQR 19.4), with 36 (64.3%) patients considered at high-risk. Both algorithms revealed a significant role of some traditional risk factors and a noteworthy potential protective role of endothelin receptor antagonists (p=0.003). QRISK3 was also significantly influenced by some SSc-specific characteristics, as limited cutaneous subset (p=0.01), interstitial lung disease (p=0.04) and non-ischemic heart involvement (p=0.03), with the first two that maintain statistically significance in the multivariate analysis (p=0.02 for both).Conclusion:QRISK3 classifies more SSc patients at high-risk to develop CV diseases than Framingham, and it seems to be influenced by some SSc-specific characteristics. If its predictive accuracy were prospectively verified, the use of QRISK3 as a tool in the early detection of SSc patients at high CV risk should be recommended.References:[1]Ngian GS, Sahhar J, Proudman SM, Stevens W, Wicks IP, Van Doornum S. Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis. Ann Rheum Dis. 2012;71:1980-3.Disclosure of Interests:None declared


2021 ◽  
Vol 4 (2) ◽  
pp. 38-50
Author(s):  
Victoria Ysabel Bringas Rios

Knowledge management and continuous improvement are key success factors that are applied in organizations independently; However, there is a significant relationship between the two, therefore organizations that seek to be leaders in their sector must analyze them together. Considering that universities have a leading role and must transcend the expectations of our society, I have considered it pertinent to carry out this article whose purpose is to establish the relationship between Knowledge Management and Continuous Improvement in a Private University from Lima, Peru. It has a quantitative approach because statistical analysis was used to test what was established in the hypotheses. The design is non-experimental, cross-sectional, since information is presented as it occurs in reality and in a given time, it is transectional, correlational, because it measures and evaluates the relationship between the variables. The sample is made up of 45 individuals between heads of areas and school coordinators, to whom a questionnaire with 32 questions was applied, whose data were processed in the statistical program SPSS version 25. Finally, the significant relationship between management of the knowledge and continuous improvement, obtaining a Spearman Rho, 0.730, at the 1% level of significance. Likewise, the findings affirm that the phases of creating, storing, applying and transferring knowledge also have a significant relationship with continuous improvement.


2018 ◽  
Vol 6 (1) ◽  
pp. 43
Author(s):  
Desy Amanda ◽  
Santi Martini

Background: The prevalence of hypertension in Indonesia was 25,80% in 2013 found in people aged above 18 years old. One of the risk factors is obesity. Purpose: This study aimed to analyze the relationship between the demographical characteristic and central obesity with the risk of hypertension in the health center of Sidoarjo. Methods: This analytical observational study design was cross sectional. There were 50 respondents selected through accidental sampling. The independent variables of this study were respondents’ characteristic and central obesity status. However, the dependent variable was hypertension. Overall, respondents were divided into two groups based on sex (female and male) and age (> 59 years old and ≤ 59 years old). Data were analyzed with chi-square statistical analysis. Results: Respondents with central obesity had a higher risk to get hypertension, with majority male respondents aged above 59 years old. Conclusion: There was a correlation between age and hypertension (p = 0,01), sex and hypertension (p = 0,04), also between central obesity status and hypertension (p = 0,01). 


Author(s):  
Verra Widhi Astuti ◽  
Tasman Tasman ◽  
Lola Felnanda Amri

ABSTRAK Pendahuluan: Hipertensi disebut sebagai "silent killer" artinya dapat menyebabkan kematian secara diam-diam. Hanya melalui pengukuranlah deteksi dapat dilakukan. Penelitian ini bertujuan untuk mengetahui prevalensi hipertensi dan faktor-faktor yang mempengaruhi hipertensi di Wilayah Kerja Puskesmas Nanggalo, Padang. Metode: Penelitian ini menggunakan metode survei analitik dengan pendekatan cross sectional. Penelitian dilakukan pada masyarakat usia > 18 tahun di wilayah Kerja Puskemas Nanggalo dengan sampel sebanyak 438 responden. Hasil: Hasil penelitian menunjukkan bahwa proporsi hipertensi di masyarakat Wilayah Kerja Nanggalo tahun 2019 sebesar 13,7 yang terdiri dari 10,7% hipertensi stage 1 dan 3% hipertensi stage 2. Sedangkan 19,2% responden sudah memasuki tahap pra hipertensi. Responden paling banyak pada usia produktif yaitu pada rentang usia 18-50 tahun; responden antara laki-laki dan perempuan jumlahnya hampir sama; sebagian besar memiliki status gizi (IMT) normal (64,2%), sebagian besar responden beraktivitas fisik secara rutin (77,9%); sebagian besar responden tidak merokok (61%); dan konsumsi makanan tinggi lemak jenuh dan rendah lemak jenuh hampir sama. Kesimpulan: Ada hubungan yang signifikan antara usia, berat badan (IMT) dan aktivitas fisik dengan kejadian hipertensi. Serta tidak ada hubungan yang signifikan antara jenis kelamin, kebiasaan merokok, dan makan makanan berlemak jenuh dengan kejadian hipertensi. Hasil penelitian ini diharapkan mampu meningkatkan kesadaran responden terhadap faktor-faktor risiko hipertensi.   Kata kunci: Faktor risiko, hipertensi,  prevalensi.   ABSTRACT Introduction: Hypertension is called the "silent killer" which means it can cause death silently. Therefore, detection can only be done through measurement. This study aims to determine the prevalence of hypertension and the risk factors that influence hypertension in the working area of ​​the Nanggalo Community Health Center, Padang. Methods: This study used an analytic survey method with a cross sectional approach. The research was conducted on people aged> 18 years in the working area of ​​Puskemas Nanggalo with 438 respondents as a sample. Result: The results showed that the proportion of hypertension in Nanggalo Work Area was 13.7 consisting of 10.7% stage 1 hypertension and 3% stage 2 hypertension. While 19.2% of respondents had entered the pre hypertension stage. Most respondents are in productive age, namely in the age range 18-50 years; the number of respondents between men and women is almost the same; most of them had normal nutritional status (BMI) (64.2%), most of the respondents had regular physical activity (77.9%); most of the respondents do not smoke (61%); and consumption of foods high in saturated fat and low in saturated fat is about the same. Conclusion: There is a significant relationship between age, body weight (BMI) and physical activity with the incidence of hypertension. And there is no significant relationship between gender, smoking habits, and eating saturated fatty foods with the incidence of hypertension. The results of this study are expected to be able to increase respondents' awareness of risk factors for hypertension.   Keywords: Hypertension, prevalence, risk factor


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