scholarly journals Chronic Q Fever in Alberta: A Case ofCoxiella burnetiiMycotic Aneurysm and Concomitant Vertebral Osteomyelitis

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
William Stokes ◽  
Jack Janvier ◽  
Stephen Vaughan
Keyword(s):  
Coxiella Burnetii ◽  
Vascular Tissue ◽  
Open Repair ◽  
Q Fever ◽  
Vertebral Osteomyelitis ◽  
Abdominal Aortic ◽  
Chronic Q Fever ◽  
Life Threatening ◽  
History Of ◽  
Polymerase Chain

Chronic Q fever is a potentially life-threatening infection from the intracellular, Gram-negativeCoxiella burnetii. It presents most commonly as endocarditis or vascular infection in people with underlying cardiac or vascular disease. We discuss a case of a 67-year-old male withCoxiella burnetiivascular infection of a perirenal abdominal aortic graft. The patient had a history of an abdominal aortic aneurysm (AAA) repair 5 years earlier. He presented with a 12 × 6 × 8 cm perirenal pseudoaneurysm and concomitant L1, L2, and L3 vertebral body discitis. He underwent an open repair which revealed a grossly infected graft perioperatively. Q fever serology revealed phase I serological IgG titer of 1 : 2048 and phase II 1 : 1024 consistent with chronic Q fever. Polymerase chain reaction (PCR) on infected vascular tissue was positive forC. burnetii. The patient was started on doxycycline and hydroxychloroquine with good clinical response and decreasing serological titers. Recognizing chronic Q fever is a difficult task as symptoms are nonspecific, exposure risk is difficult to ascertain, and diagnosis is hidden from conventional microbiological investigations. Its recognition, however, is critical asC. burnetiiis inherently resistant to standard empiric therapies used in cardiovascular infections.

scholarly journals Chronic Q-Fever (Coxiella burnetii) Causing Abdominal Aortic Aneurysm and Lumbar Osteomyelitis: A Case Report

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
P. Alexander Leahey ◽  
Steven R. Tahan ◽  
Ekkehard M. Kasper ◽  
Mary Albrecht
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Coxiella Burnetii ◽  
Q Fever ◽  
Prolonged Treatment ◽  
Chain Reaction ◽  
Abdominal Aortic ◽  
Chronic Q Fever ◽  
Polymerase Chain ◽  
Ig G

Abstract Coxiella burnetii is a rare cause of chronic infection that most frequently presents as endocarditis. We report a case of C burnetii causing an infected abdominal aortic aneurysm with contiguous lumbar osteomyelitis resulting in spinal cord compromise. The diagnosis was established by serologic studies consistent with chronic Q-fever (ratio of C burnetii immunoglobulin [Ig]G phase II titer to IgG phase I titer <1) and was confirmed by positive C burnetii polymerase chain reaction of vertebral tissue in addition to pathology of vertebral bone showing intracellular Gram-negative coccobacillary bacteria. The patient clinically improved after surgical decompression and prolonged treatment with doxycycline and hydroxychloroquine.

scholarly journals Endovascular Thoracoabdominal Replacement after Total Abdominal Aortic Debranching

Aorta ◽  
2018 ◽  
Vol 06 (01) ◽  
pp. 043-045 ◽  
Author(s):  
Murat Ugurlucan ◽  
Yilmaz Onal ◽  
Omer Sayin ◽  
Feza Ekiz ◽  
Didem Oztas ◽  
...  
Keyword(s):  
Marfan Syndrome ◽  
Open Repair ◽  
Connective Tissue Disorder ◽  
Thoracoabdominal Aneurysm ◽  
Stent Grafting ◽  
Abdominal Aortic ◽  
Cardiovascular Involvement ◽  
Life Threatening ◽  
History Of ◽  
Aortic Pathologies

AbstractMarfan syndrome is an inherited connective tissue disorder affecting mainly eyes and skeletal and cardiovascular systems. Cardiovascular involvement may lead to life-threatening aortic pathologies including aneurysms and/or dissections. In this report, the authors present images of a patient with Marfan syndrome with a history of Bentall-De Bono procedure followed by aortic arch and infrarenal aortoiliac replacements who strongly refused conventional open repair and underwent abdominal debranching followed by thoracoabdominal endovascular stent grafting for the treatment of thoracoabdominal aneurysm.

Estimated prevalence of chronic Q fever among Coxiella burnetii seropositive patients with an abdominal aortic/iliac aneurysm or aorto-iliac reconstruction after a large Dutch Q fever outbreak

2014 ◽  
Vol 69 (2) ◽  
pp. 154-160 ◽  
Author(s):  
Julia C.J.P. Hagenaars ◽  
Peter C. Wever ◽  
André S. van Petersen ◽  
Peter J. Lestrade ◽  
Monique G.L. de Jager-Leclercq ◽  
...  
Keyword(s):  
Coxiella Burnetii ◽  
Q Fever ◽  
Iliac Aneurysm ◽  
Abdominal Aortic ◽  
Chronic Q Fever

scholarly journals A Case of Primary Aortoduodenal Fistula and Abdominal Aortic Aneurysm in a Patient with Chronic Q Fever

Aorta ◽  
2017 ◽  
Vol 05 (01) ◽  
pp. 27-29
Author(s):  
Arne de Niet ◽  
Ignace Tielliu ◽  
Paul van Schaik ◽  
Jan van den Dungen ◽  
Clark Zeebregts
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Medical Treatment ◽  
Causative Agent ◽  
Q Fever ◽  
Aortoduodenal Fistula ◽  
Abdominal Aortic ◽  
Chronic Q Fever ◽  
History Of

AbstractA 70-year-old man was successfully treated for an aortoduodenal fistula originating from a Q fever-related abdominal aortic aneurysm. He had no known history of contact with cattle or sheep. Although the combination of abdominal aortic aneurysm and aortoduodenal fistula is rare, one should be suspicious of Q fever infection as the causative agent, and additional medical treatment should be initiated.

A RARE CASE OF NEONATE WITH SEVERE LUNG DISEASE SECONDARY TO COVID 19 DISEASE

2021 ◽  
pp. 4-5
Author(s):  
Vishal Dnyaneshwar Sawant ◽  
Murtuja Shaikh ◽  
Sushma Malik ◽  
Poonam Wade ◽  
Santosh Kondekar
Keyword(s):  
Age Groups ◽  
Severe Infection ◽  
Complete Recovery ◽  
Nasopharyngeal Swab ◽  
Global Pandemic ◽  
Similar Disease ◽  
Life Threatening ◽  
History Of ◽  
Polymerase Chain ◽  
Protective Strategies

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome Corona virus 2 (SARS-CoV-2), has caused a global pandemic affecting many countries. The disease is affecting all age groups but data so far has shown that infants and children seem to be at a lower risk of severe infection. This case emphasis that neonates too can have life threatening pulmonary disease that mimics a similar disease course to that described in adults with COVID-19 infection. We report a 21-day-old neonate who presented with fever and signicant positive history of COVID 19 infection in family and developed acute respiratory distress syndrome (ARDS). The SARSCoV-2 polymerase chain reaction (PCR) of nasopharyngeal swab was positive and chest computed tomography had classical changes of COVID 19 infection. Good hydration, lung protective strategies, intravenous immunoglobulin and supportive care led to complete recovery in the patient.

scholarly journals Assessment of Coxiella burnetii presence after tick bite in north-eastern Poland

Infection ◽  
2019 ◽  
Vol 48 (1) ◽  
pp. 85-90
Author(s):  
Karol Borawski ◽  
Justyna Dunaj ◽  
Piotr Czupryna ◽  
Sławomir Pancewicz ◽  
Renata Świerzbińska ◽  
...  
Keyword(s):  
Coxiella Burnetii ◽  
Blood Donors ◽  
Q Fever ◽  
Phase 1 ◽  
Molecular Study ◽  
Tick Bite ◽  
Control Group ◽  
Tick Borne Encephalitis ◽  
North Eastern ◽  
History Of

Abstract Purpose The aim of the study is to assess anti-Coxiella burnetii antibodies presence in inhabitants of north-eastern Poland, to assess the risk of Q fever after tick bite and to assess the percentage of co-infection with other pathogens. Methods The serological study included 164 foresters and farmers with a history of tick bite. The molecular study included 540 patients, hospitalized because of various symptoms after tick bite. The control group consisted of 20 honorary blood donors. Anti-Coxiella burnetii antibodies titers were determined by Coxiella burnetii (Q fever) Phase 1 IgG ELISA (DRG International Inc. USA). PCR was performed to detect DNA of C. burnetii, Borrelia burgdorferi and Anaplasma phagocytophilum. Results Anti-C. burnetii IgG was detected in six foresters (7.3%). All foresters with the anti-C. burnetii IgG presence were positive toward anti-B. burgdorferi IgG and anti-TBE (tick-borne encephalitis). Anti-C. burnetii IgG was detected in five farmers (6%). Four farmers with anti-C. burnetii IgG presence were positive toward anti-B. burgdorferi IgG and two with anti-TBE. Among them one was co-infected with B. burgdorferi and TBEV. Correlations between anti-C. burnetii IgG and anti-B. burgdorferi IgG presence and between anti-C. burnetii IgG presence and symptoms of Lyme disease were observed. C. burnetii DNA was not detected in any of the 540 (0%) patients. Conclusions C. burnetii is rarely transmitted by ticks, but we proved that it is present in the environment, so it may be a danger to humans. The most common co-occurrence after tick bite concerns C. burnetii and B. burgdorferi.

scholarly journals A combination of interferon-gamma and interleukin-2 production by Coxiella burnetii-stimulated circulating cells discriminates between chronic Q fever and past Q fever

2014 ◽  
Vol 20 (7) ◽  
pp. 642-650 ◽  
Author(s):  
T. Schoffelen ◽  
T. Sprong ◽  
C.P. Bleeker-Rovers ◽  
M.C.A. Wegdam-Blans ◽  
A. Ammerdorffer ◽  
...  
Keyword(s):  
Interferon Gamma ◽  
Coxiella Burnetii ◽  
Q Fever ◽  
Interleukin 2 ◽  
Circulating Cells ◽  
Chronic Q Fever

Identification of Persistent Aortocaval Fistula Using Ultrasonography in the Outpatient Setting: A Case Report

2020 ◽  
Vol 44 (3) ◽  
pp. 150-153
Author(s):  
Richard A. Meena ◽  
Melissa N. Warren ◽  
Thomas E. Reeve ◽  
Olamide Alabi
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Case Report ◽  
Surgical Repair ◽  
Outpatient Setting ◽  
Aortocaval Fistula ◽  
Abdominal Aortic ◽  
Life Threatening ◽  
History Of ◽  
Life Threatening Complication

Aortocaval fistula (ACF) is a rare and life-threatening complication associated with rupture of an abdominal aortic aneurysm (rAAA). Early detection and management of ACF’s during surgical repair of rAAAs is recommended to reduce the risk of future aneurysm-related complications, including mortality. There is a paucity of current literature on the natural history of ACFs postendovascular exclusion. We present a case study describing the detection of a persistent ACF by duplex ultrasonography (DU) postendovascular aortic repair (EVAR).

scholarly journals The prevalence of Coxiella burnetii in ticks and animals in Slovenia

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Nataša Knap ◽  
Diana Žele ◽  
Urška Glinšek Biškup ◽  
Tatjana Avšič-Županc ◽  
Gorazd Vengušt
Keyword(s):  
Coxiella Burnetii ◽  
Q Fever ◽  
Primary Source ◽  
Domestic Animals ◽  
Animal Blood ◽  
Blood Samples ◽  
Specific Antibodies ◽  
Source Of Infection ◽  
History Of ◽  
Pathogen Dna

Abstract Background The obligate intracellular bacterium Coxiella burnetii causes globally distributed zoonotic Q fever. Ruminant livestock are common reservoirs of C. burnetii. Coxiella burnetii are shed in large numbers in the waste of infected animals and are transmitted by inhalation of contaminated aerosols. This study was conducted to evaluate the prevalence of C. burnetii infection in domestic animals and ticks in areas of Slovenia associated with a history of Q fever outbreaks. Results A total of 701 ticks were collected and identified from vegetation, domestic animals and wild animals. C. burnetii DNA was detected in 17 out of 701 (2.4%) ticks. No C. burnetii DNA was found in male ticks. Ticks that tested positive in the PCR-based assay were most commonly sampled from wild deer (5.09%), followed by ticks collected from domestic animals (1.16%) and ticks collected by flagging vegetation (0.79%). Additionally, 150 animal blood samples were investigated for the presence of C. burnetii-specific antibodies and pathogen DNA. The presence of pathogen DNA was confirmed in 14 out of 150 (9.3%) blood samples, while specific antibodies were detected in sera from 60 out of 150 (40.4%) animals. Conclusions Our results indicate that ticks, although not the primary source of the bacteria, are infected with C. burnetii and may represent a potential source of infection for humans and animals. Ticks collected from animals were most likely found to harbor C. burnetii DNA, and the infection was not lost during molting. The persistence and distribution of pathogens in cattle and sheep indicates that C. burnetii is constantly present in Slovenia.

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