scholarly journals Pasteurella multocidaBacteremia in an Immunocompromised Patient

2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Shweta Kukrety ◽  
Jai Parekh ◽  
Theresa Townley
Keyword(s):  
Diabetes Mellitus ◽  
Pasteurella Multocida ◽  
Immunocompromised Patient ◽  
Altered Mental Status ◽  
Blood Cultures ◽  
Uneventful Recovery ◽  
Source Of Infection ◽  
Uncontrolled Diabetes ◽  
History Of ◽  
High Index Of Suspicion

We present the case of a 61-year-old Caucasian gentleman who presented with a one-day history of fever, chills, and altered mental status. His symptoms were initially thought to be secondary to cellulitis. Blood cultures grewPasteurella multocida, a rare pathogen to cause bacteremia. Our patient was treated with ciprofloxacin for two weeks and made a complete and uneventful recovery. Our patient’s uncontrolled diabetes mellitus and chronic kidney disease put him at a higher risk for developing seriousP. multocidainfection. The patient’s dog licking the wounds on his legs was considered as the possible source of infection. AsP. multicodabacteremia is rare, but severe with a high mortality rate, it is imperative to have a high index of suspicion for this infection especially in the vulnerable immunocompromised population.

Streptococcus salivarius endogenous endophthalmitis

2021 ◽  
Vol 14 (2) ◽  
pp. e239299
Author(s):  
Carl-Joe Mehanna ◽  
Lea Kallassi ◽  
Ahmad M Mansour ◽  
Rola N Hamam
Keyword(s):  
Opportunistic Infections ◽  
External Source ◽  
Endogenous Endophthalmitis ◽  
Streptococcus Salivarius ◽  
Source Of Infection ◽  
Transcatheter Aortic Valve ◽  
History Of ◽  
Atypical Presentations ◽  
High Index Of Suspicion ◽  
Valve Implantation

We describe a case of endogenous endophthalmitis in an elderly man caused by Streptococcus salivarius. An 88-year-old male patient with diabetes with iron deficiency anaemia and history of transcatheter aortic valve implantation presented with an insidious clinical picture of atraumatic endophthalmitis. No internal or external source could be identified. Diagnostic and therapeutic vitrectomy revealed papillomacular abscess and vitreous fluids grew S. salivarius. Despite lack of an identifiable source of infection, a high index of suspicion for atypical presentations is required in patients with multiple comorbidities that could weaken their immune system towards opportunistic infections. Early detection, microbiological evaluation and prompt treatment are critical to avoid disastrous outcomes. While S. salivarius has been implicated in cases of exogenous endophthalmitis, this is the first reported case of endogenous endophthalmitis due to S. salivarius.

scholarly journals Rhino-orbital COVID-19 associated mucormycosis- A case report

2021 ◽  
Vol 7 (4) ◽  
pp. 304-307
Author(s):  
Shanmuga Vadivoo Natarajan ◽  
B Usha
Keyword(s):  
Diabetes Mellitus ◽  
Infectious Disease ◽  
Case Report ◽  
Tertiary Care ◽  
Notifiable Disease ◽  
Health Ministry ◽  
First Case ◽  
Uncontrolled Diabetes ◽  
History Of ◽  
Second Wave

COVID-19 Associated Mucormycosis (CAM) is an emerging infectious disease that has caused increased mortality & morbidity in India during this second wave of the pandemic. The country has reported more than 30,000 cases and over 2,000 deaths by Mucormycosis so far, according to sources from Union Health Ministry. CAM is now a notifiable disease. At our Tertiary care teaching hospital, which caters for COVID 19 management, we are reporting the first case of Rhino orbital CAM, which was caused by Rhizopus spp. Our patient had a history of contact with a suspected COVID 19 patient and was recently diagnosed with uncontrolled diabetes mellitus. A direct KOH microscopic examination of purulent material aspirated from the sinonasal polyp of the patient revealed fungal elements, and Rhizopus spp was isolated. Due to a shortage of Amphotericin B, the patient was referred to a government higher speciality centre for further management. The patient was followed up & was noted that he was treated with antifungal and discharged following recovery.

scholarly journals Molecular Identification and Epidemiological Tracing of Pasteurella multocida Meningitis in a Baby

2000 ◽  
Vol 38 (3) ◽  
pp. 1235-1237 ◽  
Author(s):  
Patrick Boerlin ◽  
Hans H. Siegrist ◽  
André P. Burnens ◽  
Peter Kuhnert ◽  
Purita Mendez ◽  
...  
Keyword(s):  
Pasteurella Multocida ◽  
Close Contact ◽  
Gene Sequencing ◽  
16S Rrna Gene Sequencing ◽  
Rrna Gene ◽  
Source Of Infection ◽  
Subspecies Level ◽  
History Of ◽  
Rrna Gene Sequencing ◽  
The One

We report a case of Pasteurella multocida meningitis in a 1-month-old baby exposed to close contact with two dogs and a cat but without any known history of injury by these animals. 16S rRNA gene sequencing of the isolate from the baby allowed identification at the subspecies level and pointed to the cat as a possible source of infection. Molecular typing of Pasteurella isolates from the animals, from the baby, and from unrelated animals clearly confirmed that the cat harbored the same P. multocidasubsp. septica strain on its tonsils as the one isolated from the cerebrospinal fluid of the baby. This case stresses the necessity of informing susceptible hosts at risk of contracting zoonotic agents about some basic hygiene rules when keeping pets. In addition, this study illustrates the usefulness of molecular methods for identification and epidemiological tracing ofPasteurella isolates.

scholarly journals Rat Bite Fever Resembling Rheumatoid Arthritis

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Ripa Akter ◽  
Paul Boland ◽  
Peter Daley ◽  
Proton Rahman ◽  
Nayef Al Ghanim
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Presentation ◽  
Blood Cultures ◽  
Zoonotic Infection ◽  
Presumptive Diagnosis ◽  
Rat Bite Fever ◽  
Rare Manifestation ◽  
History Of ◽  
High Index Of Suspicion ◽  
Culture Positive

Rat bite fever is rare in Western countries. It can be very difficult to diagnose as blood cultures are typically negative and a history of rodent exposure is often missed. Unless a high index of suspicion is maintained, the associated polyarthritis can be mistaken for rheumatoid arthritis. We report a case of culture-positive rat bite fever in a 46-year-old female presenting with fever and polyarthritis. The clinical presentation mimicked rheumatoid arthritis. Infection was complicated by discitis, a rare manifestation. We discuss the diagnosis and management of this rare zoonotic infection. We also review nine reported cases of rat bite fever, all of which had an initial presumptive diagnosis of a rheumatological disorder. Rat bite fever is a potentially curable infection but can have a lethal course if left untreated.

ID: 48: VEILLONELLA BACTEREMIA IN AN IMMUNOCOMPROMISED PATIENT

2016 ◽  
Vol 64 (4) ◽  
pp. 954.1-954
Author(s):  
J Kim ◽  
M Beilke
Keyword(s):  
Physical Examination ◽  
Intestinal Tract ◽  
Cell Lymphoma ◽  
Immunocompromised Patient ◽  
Blood Cultures ◽  
Indwelling Catheters ◽  
Commensal Flora ◽  
Serious Infections ◽  
Mantle Cell ◽  
History Of

Veillonellaspecies are anaerobic gram-negative cocci that are commensal flora of the mouth, intestinal tract, skin, and genital tract. Bacteremia with this organism is rarely reported. We report a case of Veillonella bacteremia in an immunocompromised patient. The patient was a 58 year old male with a history of refractory mantle cell lymphoma, receiving ibrutinib. He presented with high fevers and neutropenia. The patient had no indwelling catheters. Physical examination was negative, except for evidence of gingivitis. Veillonella was isolated from patient's blood cultures. The patient was successfully treated with meropenem. It was suspected that the source of the infection was the oral cavity. This case illustrates the significance of normal commensal flora as possible causes of serious infections in the immunocompromised patient. The case also illustrates the need to conduct a thorough physical examination when an unexpected pathogen is identified.

Severe Ludwig’s angina caused by an unknown insect bite

2021 ◽  
Vol 14 (8) ◽  
pp. e243566
Author(s):  
Gihad Almadhi ◽  
Mohammed Alkathlan ◽  
Othman Alharbi ◽  
Ahmad Almeman
Keyword(s):  
Intensive Care Unit ◽  
Blood Cultures ◽  
Source Of Infection ◽  
Intravenous Antibiotics ◽  
Facial Swelling ◽  
History Of ◽  
Ludwig’S Angina ◽  
Insect Bites ◽  
Left Parotid Gland ◽  
Ludwig's Angina

Hereby, we report a case of a 75-year-old man who presented with a 3-day history of facial swelling and choking sensation. The only history of note was an insect bite on the left parotid gland area 3 days prior. The patient was later diagnosed with insect-bite-induced Ludwig’s angina. Enterococcus faecalis was detected on blood cultures and was presumed the source of infection. Intravenous antibiotics and corticosteroids were initiated. The patient was intubated and was subsequently made to undergo a tracheostomy insertion to establish a definitive airway. He was admitted to the intensive care unit and when his condition improved, he was transferred to the ward for full recovery. The patient spent a total of 66 days in hospital before being discharged. This case suggests that Ludwig’s angina can be caused by insect bites. However, further similar cases are needed to be documented to explore this theory.

Pasteurella Multocida Abscess Complicating a Femoral Vein Thrombosis

1993 ◽  
Vol 38 (3) ◽  
pp. 81-81
Author(s):  
A. Petermann ◽  
A.R. Naylor ◽  
P.K. Donnelly
Keyword(s):  
Pasteurella Multocida ◽  
Immunocompromised Patient ◽  
Femoral Vein ◽  
Vein Thrombosis ◽  
History Of ◽  
Animal Bites ◽  
Thigh Abscess

We describe the first reported case of a Pasteurella multocida thigh abscess complicating a femoral vein thrombosis in a non-immunocompromised patient with no history of animal bites or scratches.

scholarly journals Unprovoked serotonin syndrome-like presentation of SARS-CoV-2 infection: A small case series

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110320
Author(s):  
Philip Keith ◽  
Marc Saint-Jour ◽  
Frank Pusey ◽  
Jeremy Hodges ◽  
Farid Jalali ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Multiple Sclerosis ◽  
Intensive Care Unit ◽  
Serotonin Syndrome ◽  
Case Series ◽  
Altered Mental Status ◽  
Whole Body ◽  
External Cooling ◽  
High Index Of Suspicion ◽  
Serotonin Toxicity

Clinicians and researchers have reported an array of neurological abnormalities in coronavirus disease 2019 (COVID-19), and while serotonin excess has been observed we are unaware of reports of central nervous system serotonin toxicity in COVID-19. We present two cases that resemble serotonin syndrome in COVID-19, but without identifiable inciting medications. A 54-year-old with multiple sclerosis and diabetes mellitus presented with altered mental status. His altered sensorium was attributed to diabetic ketoacidosis, but his condition quickly deteriorated with fever to 105 degrees Fahrenheit, rigidity in all extremities, inducible clonus, and hyperreflexia. He was intubated and was treated for possible meningitis and seizure. Neurologic workup was negative for acute pathology. Despite acetaminophen, his core temperature remained elevated to 105 degrees Fahrenheit. He was treated with external cooling and cyproheptadine and within 48 h, his fever, rigidity, hyperreflexia, and clonus resolved. He was extubated and discharged home on day 14. A 72-year-old with hyperlipidemia was admitted with tremors, 4 days after testing positive for COVID-19. His symptoms rapidly worsened, and he was transferred to the Intensive Care Unit on day 3 in extremis, febrile to 104.4 degrees Fahrenheit, heart rate of 180 beats per minute, and apparent whole body myoclonus. He was intubated and developed fever refractory to acetaminophen requiring external cooling. Extensive neurologic workup was negative. He received cyproheptadine and slowly improved. He was extubated and discharged to rehab on day 11. These cases represent a unique presentation in COVID-19 that must be considered and requires a high index of suspicion.

scholarly journals Consequences of misdiagnosis of diabetic charcot anthropathy of the ankle

1970 ◽  
Vol 4 (2) ◽  
pp. 83-86
Author(s):  
Chowdhury Iqbal Mahmud
Keyword(s):  
Diabetes Mellitus ◽  
Ankle Fracture ◽  
Ankle Arthrodesis ◽  
Fracture Dislocation ◽  
Key Words Diabetes Mellitus ◽  
Diabetic Patients ◽  
Key Words Diabetes ◽  
Charcot Arthropathy ◽  
Uncontrolled Diabetes ◽  
History Of

Permanent deformity and disability can occur in diabetic Charcot arthropathy (neuropathic arthropathy) if not diagnosed and treated promptly. We report two patients with uncontrolled diabetes mellitus in whom the diagnosis of ankle neuro-arthropathy was delayed by up to six months, with misdiagnoses including ankle arthritis, osteomyelitis and cellulitis. The clinical scenario and appearances of the ankle and foot were typical of Charcot arthropathy. Unfortunately, both of them sustained ankle fracture-dislocation without a history of significant trauma. Both the patients were treated by ankle arthrodesis (fusion of joint). Prevention and early diagnosis of diabetic foot is the key to avoid the development of complications. In diabetic patients, a higher index of suspicion for the possibility of Charcot’s disease is needed. Key Words: Diabetes mellitus; Charcot arthropathy; ankle fracture-dislocation; arthrodesis. DOI: 10.3329/imcj.v4i2.6503Ibrahim Med. Coll. J. 2010; 4(2): 83-86

scholarly journals AYURVEDIC MANAGEMENT OF WAGNER’S GRADE II DIABETIC ULCER - A CASE STUDY

2021 ◽  
Vol 09 (3) ◽  
pp. 657-662
Author(s):  
Sreeja Pillai ◽  
Nitin Kamat ◽  
Hemant Paradkar ◽  
Anaya Pathrikar
Keyword(s):  
Diabetes Mellitus ◽  
Growth Factors ◽  
Foot Ulcer ◽  
Diabetic Ulcer ◽  
Uncontrolled Diabetes ◽  
Bowel Movements ◽  
History Of ◽  
Grade Ii ◽  
Wagner’S Grade

Diabetic ulcer has been a challenge to be tackled since there is deficiency of growth factors and impaired immunity, which can lead to amputation if timely intervention is not done. A 59-year-old male patient with a history of uncontrolled diabetes mellitus for 10 years presented with a non-healing foot ulcer since 1year. He was managed with Ayurvedic internal and external medications at OPD level. After 3 months, the outcome was encouraging with complete epithelialization along with improvement in his generalized complaints like lethargy, irregular bowel movements etc.

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