scholarly journals Mood, Disability, and Quality of Life among a Subgroup of Rheumatoid Arthritis Individuals with Experiential Avoidance and Anxiety Sensitivity

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
S. Mehta ◽  
D. Rice ◽  
S. Janzen ◽  
J. E. Pope ◽  
M. Harth ◽  
...  

Objective.The current study aimed to identify and characterize distinct RA subgroups based on their level of EA and AS and compares the difference among the subgroups in mood, disability, and quality of life.Methods.Individuals with chronic pain for at least 3 months were recruited from an academic rheumatoid clinic. Participants were assessed for demographic, psychosocial, and personality measures. A two-step cluster analysis was conducted to identify distinct subgroups of patients. Differences in clinical outcomes were compared using the Multivariate ANOVA based on cluster membership.Results.From a total of 223 participants, three distinct subgroups were formed based on cluster analysis. Cluster 1 (N=78) included those with low levels of both EA and AS. Cluster 2 (N=81) consisted of individuals with moderate levels of EA and low levels AS. Cluster 3 (N=64) included those with moderate levels of EA and high AS. Compared to those in Cluster 1, those in Cluster 3 had significantly higher levels of mood impairment and disability and lower quality of life (p<0.05). Significantly lower levels of mood impairment were seen in Cluster 1 compared to Cluster 2 (p<0.05). However, no significant difference in disability or quality of life was seen between the two groups.Conclusions.The three subgroups differed significantly in levels of impairment in mood, disability, and quality of life. However, levels of EA had a greater impact on disability and quality of life than AS.

Author(s):  
Shaista Shaban ◽  
Mohd Abrar Ahmad Guroo ◽  
Racheal Bashir

Background: Quality of life (QOL) is a measure to see an individual’s adaptation and feeling of wellbeing and adjustment with the surroundings. Schizophrenia and rheumatoid arthritis (RA) both are chronic and disabling disorders supposed to have significant effect on quality of life. Also chronicity and disability of these disorders can be directly proportional to the caregiver burden.Methods: Comparative study assessing quality of life and caregiver burden between persons with schizophrenia and RA.Results: 50% of the schizophrenia group as well as the RA group were unemployed, suggesting the magnitude of the disability levels caused by the illness. Only 33% of patients with schizophrenia were married, unlike patients with RA where 83% were married. Of all the four domains of the World Health Organization quality of life instrument (WHO-QOL BREF) both the groups scored highest in the physical domain and least in the psychological domain and the difference between the two groups was not statistically significant in all the four domains. Burden among the caregivers of schizophrenic patients was comparatively high on BAS than caregivers of rheumatoid arthritis. The mean duration of illness in patients with schizophrenia was significantly higher than patients with RA.Conclusions: RA is a chronic disorder and physical in nature with full insight in the patients. While as schizophrenia is characterized as a chronic mental illness with poor prognosis and no insight. QOL is expected to be less in schizophrenic patients. There is no significant difference in QOL except in physical domain in which patients with schizophrenia scored significantly better than patients with RA. The social domain of QOL was the only one in which schizophrenic patients did poorly, though not statistically significant. Also care giver burden was more among caregivers of schizophrenic patients and that can be attributed to lack of insight.


Medicina ◽  
2019 ◽  
Vol 55 (5) ◽  
pp. 124
Author(s):  
Daniel López-López ◽  
Roi Painceira-Villar ◽  
Vanesa García-Paz ◽  
Ricardo Becerro-de-Bengoa-Vallejo ◽  
Marta Elena Losa-Iglesias ◽  
...  

Background: Asthma may be considered as a non-communicable condition associated with higher bronchial responsiveness that may impair quality of life (QoL). Purpose: The research aim was to compare scores of depression, as well as general and foot health-related QoL, in patients who suffered from asthma with respect to healthy subjects. Methods: A total sample of 152 subjects, median age of 37.00 ± 16.00 years, were recruited from a respiratory and allergy department of a hospital and divided into patients with asthma (n = 76) and healthy subjects (n = 76). The scores of the Spanish foot health status questionnaire (SFHSQ) domains as well as the Spanish Beck’s Depression Inventory (BDI) scores and categories were collected. Results: The only statistically significant difference (p < 0.05) was shown for the difference of the FHSQ footwear domain establishing that patients who suffered from asthma presented a worse QoL related to foot health for footwear (lower FHSQ scores) compared to healthy matched-paired participants (higher FHSQ scores). Regarding the rest of the outcome measurements, there were no statistically significant differences (p > 0.05) for the other FHSQ domains scores as well as the BDI scores and categories. Conclusions: Patients with allergic asthma presented impairment of the QoL related to foot health for footwear, which seemed to be linked to the presence of asthma.


2017 ◽  
Vol 3 (2) ◽  
pp. 38
Author(s):  
Sinta Fresia

Abstrak Latar Belakang : Terjadinya peningkatan jumlah pasien HIV/AIDS dan rendahnya kualitas hidup pasien HIV/AIDS menimbulkan masalah yang cukup luas pada individu yang terinfeksi yakni masalah fisik, social dan emosional.Untuk meningkatkan kualitas dan harapan hidup pasien HIV/AIDS harus mendapatkan terapi Antiretrovirus (ARV) seumur hidup dan dibutuhkan pengawasan terhadap kepatuhan minum obat.Oleh karena itu pasien HIV/AIDS membutuhkan edukasi untuk meningkatkan kepatuhan minum obat dengan metode terbaru yaitu tutorial dan audiovisual.Tujuan penelitian ini untuk menganalisa perbedaan efektivitas pemberian edukasi berbasis audiovisual dan tutorial tentang ARV terhadap kepatuhan pengobatan pasien HIV/ AIDS. Metode : Penelitian ini menggunakan desain Quasi eksperimental dengan rancangan pretest-posttes design without control group.Jumlah sampel 27 responden dibagi 3 kelompok dengan 3 perlakuan berbeda.Masing-masing 9 responden diberikan edukasi dengan metode audiovisual, tutorial, audiovisual dan tutorial.Penelitian dilakukan di Klinik Teratai Rumah Sakit Hasan Sadikin Bandung pada bulan Mei-Juni 2016. Hasil : Ada perbedaan rata-rata mean kepatuhan edukasi dengan audiovisual 2,444, (Pvalue=0,003, 95% CI=1,107-3,782), edukasi dengan metode tutorial perbedaan mean 1,556 (Pvalue=0,023, 95% CI=1,274-2,837), edukasi dengan audiovisual dan tutorial didapatkan perbedaan mean 3,667 (Pvalue=0,003, 95% CI=1,670-5,664). Kesimpulan : Terdapat perbedaan yang significant rata-rata kepatuhan pada masing-masing kelompok intervensi edukasi.Kombinasi edukasi berbasis audiovisual dan tutorial memberikan hasil yang paling baik. Abstract Background : An increasing number of patients with HIV/AIDS and low quality of life of patients with HIV/AIDS cause considerable problems in individuals infected area.There are physical, social and emotional problems.To improve the quality of life of receive antiretroviral (ARV) therapy for life.This requires adherence and supervision taking medication. There fore urgently needed education to improve adherence with the latest audiovisual and tutorial methods. The purpose of this research is to analyze the difference effectiveness of education based audiovisual and tutorial method on ARV treatment adherence with HIV/AIDS patients.Methods : This research use quasi experimental design with pretest and posttest without control group. The numbers of sample in this research is 27 sample. Responden group divided into three different education methode. 9 responden in audiovisual methode,9 responden in tutorial methode and 9 responden in audiovisual and tutorial methode. The study was conducted at the Clinic Teratai Hasan Sadikin Hospital in May-June, 2016. Results : There is a diference in average adherence. In audiovisual methode mean 2,444 (Pvalue=0,003, 95% CI=1,107-3,782), tutorial methode 1,556(Pvalue=0,023, 95% CI=1,274-2,837), audiovisual and tutorial methode mean 3,667 (Pvalue =0,003, 95% CI=1,670-5,664).Conclusion : There is a significant difference in the average adherence in difference methode.Especially in audiovisual and tutorial methode. The combination of audiovisual and tutorial-based education gives the best results


2020 ◽  
pp. 107110072096209
Author(s):  
Kota Shimomura ◽  
Tetsuro Yasui ◽  
Atsushi Teramoto ◽  
Yasuhiro Ozasa ◽  
Toshihiko Yamashita ◽  
...  

Background: Resection arthroplasty has long been a major treatment option for forefoot deformity caused by rheumatoid arthritis (RA). However, metatarsophalangeal (MTP) joint–preserving surgery is now surpassing classic resection arthroplasty. This study was performed to compare the postoperative results of these 2 operative methods. Methods: Fifty-one toes of 40 patients with RA who underwent resection arthroplasty (resection group) or MTP joint–preserving arthroplasty (preservation group) from 2014 to 2017 for forefoot deformity were followed up for >1 year and were retrospectively analyzed. In the preservation group, open reduction of joint dislocation was performed if needed, and the deformity was corrected by metatarsal shortening osteotomy. The mean follow-up period was 21 months. The Japanese Society for Surgery of the Foot (JSSF) scales (objective outcome measures), the Self-Administered Foot Evaluation Questionnaire (SAFE-Q) (subjective outcome measure), and radiographic indices were compared between the groups. The resection group and preservation group comprised 15 toes of 11 patients and 36 toes of 29 patients, respectively. Results: There were no significant differences in the preoperative radiographic indices, JSSF scales, or SAFE-Q results between the 2 groups. The preservation group showed better JSSF scores at the last follow-up (median hallux scale, 89 vs 74; median lesser scale, 87 vs 79). In the preservation group, the SAFE-Q scores gradually improved with time until 12 months postoperatively. In the resection group, the scores decreased 3 months postoperatively and then improved and reached a plateau 6 months postoperatively. At 12 months postoperatively, there was no significant difference in the SAFE-Q scores between the 2 groups. Conclusions: MTP joint–preserving arthroplasty resulted in superior objective scores to resection arthroplasty in patients with RA forefoot deformity. Although the subjective scores did not differ between the groups at the last follow-up, the time course of postoperative quality of life improvement was different between the 2 surgeries. Level of Evidence: Level III, retrospective comparative study.


2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Danielle B. Rice ◽  
Swati Mehta ◽  
Janet E. Pope ◽  
Manfred Harth ◽  
Allan Shapiro ◽  
...  

Background. Patients with rheumatoid arthritis may experience increased negative outcomes if they exhibit specific patterns of dispositional affect.Objective. To identify subgroups of patients with rheumatoid arthritis based on dispositional affect. The secondary objective was to compare mood, pain catastrophizing, fear of pain, disability, and quality of life between subgroups.Methods. Outpatients from a rheumatology clinic were categorized into subgroups by a cluster analysis based on dispositional affect. Differences in outcomes were compared between clusters through multivariate analysis of covariance.Results. 227 patients were divided into two subgroups. Cluster 1 (n=85) included patients reporting significantly higher scores on all dispositional variables (experiential avoidance, anxiety sensitivity, worry, fear of pain, and perfectionism; allp<0.001) compared to patients in Cluster 2 (n=142). Patients in Cluster 1 also reported significantly greater mood impairment, pain anxiety sensitivity, and pain catastrophizing (allp<0.001). Clusters did not differ on quality of life or disability.Conclusions. The present study identifies a subgroup of rheumatoid arthritis patients who score significantly higher on dispositional affect and report increased mood impairment, pain anxiety sensitivity, and pain catastrophizing. Considering dispositional affect within subgroups of patients with RA may help health professionals tailor interventions for the specific stressors that these patients experience.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1438.2-1438
Author(s):  
V. Boyadzhieva ◽  
N. Stoilov ◽  
E. Kurteva ◽  
R. Stoilov

Background:Assessment of disease activity and quality of life are one of the main indicators for determining the effectiveness of treatment with disease-modifying antirheumatic drugs. In recent years, a new group has entered the market - target synthetic DMARDS, which prove their effectiveness in treating RA comparable to that of biological products.Objectives:The aim of this study is to evaluate the disease activity and quality of life of patients with rheumatoid arthritis (RA) treated with biological agents in comparison with Tofacitinib (real life data from Bulgarian population) and determine whether or not the benefits of different therapies were sustained over a follow up period of 1 year.Methods:164 patients were selected with a mean age 55.34 ± 16SD years, meeting the 1987 ACR and /or ACR/ EULAR (2010) classification criteria for Rheumatoid arthritis (RA). Patients were arranged according to treatment regimens: Tocilizumab (TCL) 30 patients, Certolizumab (CZP) 16, Golimumab (GOL) 22, Etanercept (ETN) 20, Adalimumab (ADA) 20, Rituximab (RTX) 16, Infliximab (INF) 20, Tofacitinib (TOF) 20. Disease activity and quality of life was the primary concern. Independent joint assessor evaluated 28 joints on baseline, 6th and 12th month’s thereafter. CRP was used to measure the inflammatory process.DAS28-CRP, clinical disease activity index (CDAI) and simplified disease activity index (SDAI)were calculated. On baseline all of the patients’ groups had severe disease activity (mean DAS28-CRP > 5.2, mean CDAI > 22, mean SDAI > 26. The quality of life was evaluated via EQ-5D.All of the patients were on stable therapy according to the inclusion criteria, and didn’t interrupt any of the medications including biological or target synthetic treatment.Results:Significant clinical improvement and statistically significant reduction in disease activity were observed in patients treated with bDMARDS and tsDMARDS within 6 months (p <0.005) of treatment and after 12 months of follow-up (p=0.039). The mean value of DAS28-CRP after one year follow up showed an non-inferior effect of Tofacitnib (3.04± 0.81) in comparison to biological treatment (TCL: 3.07 ± 0.73; CZP: 3.06 ± 0.65; GOL: 2.49 ± 0.76; ETN: 2.85 ± 0.55; ADA: 3.15 ± 0.82; RTX: 2.90 ± 0.70; INF: 3.14; ± 0.61; TOF: 3.04± 0.81). An improvement was also observed for the 6 to 12 months of follow-up as we did not detect a significant difference in the activity of the disease assessed by CDAI among the different drug groups.The mean values showing the change of the SDAI over the study period also outline comparable profiles. All of the treatment groups achieved a rapid reduction in disease activity that continued to decrease through the 6 and 12 months period, respectively, as supported by changes in SDAI.The quality of life evaluated with EQ-5D revealed significant improvement on the 6-th month of follow up as well as after 12th month (p<0.005) without significant difference between the observed groups.Conclusion:Real-life data show that patients on biological treatment as well as those on Tofacitinib therapy achieve a significant decrease in disease activity after one year of follow-up. This gives us reason to accept the importance of non-inferior effect of jak-inhibitors and their place in treatment of Rheumatoid arthritis.Disclosure of Interests:Vladimira Boyadzhieva: None declared, Nikolay Stoilov: None declared, Ekaterina Kurteva: None declared, Rumen Stoilov Grant/research support from: R-Pharm


2017 ◽  
Vol 41 (S1) ◽  
pp. S454-S454
Author(s):  
K. Khemakhem ◽  
C. Sahnoun ◽  
H. Ayadi ◽  
J. Boudabbous ◽  
L. Cherif ◽  
...  

AimThe aim of our study was to investigate and compare the quality of life of parents of children with ADHD and parents of children within psychiatric troubles.MethodsWe conducted a cross sectional and comparative study, on 20 families of children with ADHD, followed in child and adolescent psychiatry department of Sfax, Tunisia, and 20 control families. We used the Short Form Health Survey (SF 36) translated and validated in Arabic to evaluate the quality of life of the parents of the two groups.ResultsThe average age of the patients of our survey was 9 years 8 months with a predominance of boys. We objectified a significant difference between the overall scores of the quality of life of parents of children with ADHD and the control sample. A highly significant difference was noted in the following areas: mental health, bodily pain and social functioning. The difference was significant in vitality score. The difference was not significant in 4 scores: general health, physical functioning, role physical, and role emotional.ConclusionFamilies with a child with ADHD have many challenges which impact certainly in their quality of life. As a child and adolescent's psychiatrics, we should be aware of these consequences in order to help the parents to improve their quality of life.Disclosure of interestThe authors have not supplied their declaration of competing interest.


2021 ◽  
Vol 24 (9) ◽  
pp. 670-677
Author(s):  
Gelareh Niakan ◽  
Samaneh Rokhgireh ◽  
Majid Ebrahimpour ◽  
Abolfazl Mehdizadeh Kashi

Background: Endometriosis is an estrogen-dependent disease that adversely affects women’s quality of life (QOL). We aimed to compare the effect of dienogest and oral contraceptive pills (OCPs) on pain and QOL in women with endometriosis. Methods: This randomized double-blind trial was conducted at Rasoul-e-Akram hospital, affiliated to Iran University of Medical Sciences, Tehran, Iran, from March 2018 to March 2020, on women with severe endometriosis confirmed by laparoscopic surgery. Ninety patients were randomly given either dienogest (Vissane 2 mg tablet; n = 30), or OCPs (LD; n = 30), or placebo (n = 30) daily for 12 weeks. The primary objective of this study was to evaluate the patient’s pain including dyspareunia, dysuria, dyschezia, and pelvic pain. The secondary outcome was considered as a change in patients’ QOL score. Results: The mean age of population was 32.99 ± 7.1 years. There was no significant difference in the three groups regarding baseline characteristics. Pelvic pain was significantly reduced, while the effect of medication on dysuria and dyschezia was not significant. The overall QOL score between the control and dienogest (P = 0.02) and OCPs groups (P = 0.001) was significantly different; however, the difference was not significant between the two intervention groups Conclusion: The finding of the present study revealed that there is no difference in the efficacy of dienogest and OCPs in management of pain and the QOL. But there was a significant difference between the placebo and intervention groups.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1943.1-1944
Author(s):  
S. Baglan Yentur ◽  
N. Atas ◽  
M. A. Ozturk ◽  
D. Oskay

Background:Rheumatoid Arthritis (RA) is a rheumatic disease that may coexist many symptoms clinically. These clinical symptoms progress in a vicious cycle in many patients. Physical activity and exercise are known to improve many symptoms in RA patients.Objectives:This study was designed to investigate the effects of clinical pilates exercises on fatigue, depression, aerobic capacity, pain, sleep quality and quality of life.Methods:Thirty voluntary RA patients were included in this study. Patients were separated into three groups equally and each group was applied treatment for eight weeks. Clinical pilates exercises were practiced to the first group, aerobic exercises were practiced to the second group and combined training which was a combination of pilates exercises and aerobic exercises was performed to the third group. Fatigue, depression, aerobic capacity, pain, sleep quality and quality of life were evaluated by Fatigue Severity Scale (FSS), Beck Depression Inventory (BDI), Six minute walk test (6MWT), Short- Form McGill Pain Questionnaire (MPQ), Pittsburg Sleep Quality Index (PSQI) and Rheumatoid Arthritis Quality of Life (RAQoL), respectively.Results:According to our results, statistically significant improvements were found for clinical pilates exercises on fatigue, depression, aerobic capacity and quality of life (p<0.05). Improvements in all parameters except from pain were concluded for aerobic exercises and combined training (p<0.05). Also, there was no statistically significant difference among the treatment groups in assessments (p>0.05).Conclusion:Pilates exercises were found effective and safe for RA patients. Clinical pilates training may be as effective as aerobic exercises in patients with RA according to our study. Therefore, addition of clinical pilates exercises to the routine treatment of RA may enhance the success of rehabilitation.References:[1]Hegarty RS, Conner TS, Stebbings S, Treharne GJ. Feel the Fatigue and Be Active Anyway: Physical Activity on High-Fatigue Days Protects Adults With Arthritis From Decrements in Same-Day Positive Mood. Arthritis care & research. 2015;67(9):1230-6[2]Løppenthin K, Esbensen BA, Jennum P, Østergaard M, Christensen JF, Thomsen T, et al. Effect of intermittent aerobic exercise on sleep quality and sleep disturbances in patients with rheumatoid arthritis–design of a randomized controlled trial. BMC musculoskeletal disorders. 2014;15(1):4Disclosure of Interests:None declared


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