scholarly journals Managing Sleep Disturbances in Cirrhosis

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Xun Zhao ◽  
Philip Wong
Keyword(s):  
Sleep Disturbances ◽  
Treatment Options ◽  
Light Therapy ◽  
Poor Quality ◽  
Poor Sleep ◽  
Obstructive Sleep ◽  
Quality Sleep ◽  
Common Problems ◽  
H1 Blockers

Sleep disturbances, particularly daytime sleepiness and insomnia, are common problems reported by patients suffering from liver cirrhosis. Poor sleep negatively impacts patients’ quality of life and cognitive functions and increases mortality. Although sleep disturbances can be an early sign of hepatic encephalopathy (HE), many patients without HE still complain of poor quality sleep. The pathophysiology of these disturbances is not fully understood but is believed to be linked to impaired hepatic melatonin metabolism. This paper provides an overview for the clinician of common comorbidities contributing to poor sleep in patients with liver disease, mainly restless leg syndrome and obstructive sleep apnea. It discusses nondrug and pharmacologic treatment options in these patients, such as the use of light therapy and histamine (H1) blockers.

scholarly journals Sleep Disruption Worsens Seizures: Neuroinflammation as a Potential Mechanistic Link

2021 ◽  
Vol 22 (22) ◽  
pp. 12531
Author(s):  
Herlinda Bonilla-Jaime ◽  
Helena Zeleke ◽  
Asheebo Rojas ◽  
Claudia Espinosa-Garcia
Keyword(s):  
Sleep Deprivation ◽  
Sleep Disturbances ◽  
Seizure Activity ◽  
Sleep Disruption ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Obstructive Sleep ◽  
Potential Link ◽  
Related Mortality

Sleep disturbances, such as insomnia, obstructive sleep apnea, and daytime sleepiness, are common in people diagnosed with epilepsy. These disturbances can be attributed to nocturnal seizures, psychosocial factors, and/or the use of anti-epileptic drugs with sleep-modifying side effects. Epilepsy patients with poor sleep quality have intensified seizure frequency and disease progression compared to their well-rested counterparts. A better understanding of the complex relationship between sleep and epilepsy is needed, since approximately 20% of seizures and more than 90% of sudden unexpected deaths in epilepsy occur during sleep. Emerging studies suggest that neuroinflammation, (e.g., the CNS immune response characterized by the change in expression of inflammatory mediators and glial activation) may be a potential link between sleep deprivation and seizures. Here, we review the mechanisms by which sleep deprivation induces neuroinflammation and propose that neuroinflammation synergizes with seizure activity to worsen neurodegeneration in the epileptic brain. Additionally, we highlight the relevance of sleep interventions, often overlooked by physicians, to manage seizures, prevent epilepsy-related mortality, and improve quality of life.

scholarly journals The critical influence of nocturnal breathing complaints on the quality of sleep after stroke: the Pittsburgh Sleep Quality Index and STOP-BANG

2017 ◽  
Vol 75 (11) ◽  
pp. 785-788 ◽  
Author(s):  
Giuliano da Paz Oliveira ◽  
Eliana Regina Lottemberg Vago ◽  
Gilmar Fernandes do Prado ◽  
Fernando Morgadinho Santos Coelho
Keyword(s):  
Sleep Quality ◽  
Quality Index ◽  
Sleep Disturbances ◽  
Pittsburgh Sleep Quality Index ◽  
Poor Quality ◽  
Quality Of Sleep ◽  
Stroke Patients ◽  
Subjective Sleep Quality ◽  
Quality Sleep

ABSTRACT In stroke patients particularly, many factors, such as sleep-related respiratory disturbances, can impair sleep. Cheap and easy-to-use tools have been created to identify sleep quality and sleep disturbances in patients after stroke. This study described the scores of the sleep apnea screening questionnaire - STOP-BANG - in patients after a stroke, and correlated the findings with sleep quality measured by the Pittsburgh Sleep Quality Index (PSQI). The scores of the STOP-BANG and PSQI were 4.3 ± 1.8 and 76 ± 3.9, respectively. The STOP-BANG scores were higher in poor sleepers (4.5 ± 1.6 versus 3.5 ± 1.9; p = 0.032). Logistic regression analysis was used to identify predictors of subjective sleep quality (PSQI) and the STOP-BANG as a predictor of poor quality sleep, with a relative risk of 1.6, controlled for age and sex. This study indicated that sleep quality was largely influenced by sleep breathing problems, which were well identified by the STOP-BANG, especially in younger stroke patients.

scholarly journals Tactile Processing and Quality of Sleep in Autism Spectrum Disorders

2021 ◽  
Vol 11 (3) ◽  
pp. 362
Author(s):  
Dominika Jamioł-Milc ◽  
Mirosława Bloch ◽  
Magdalena Liput ◽  
Laura Stachowska ◽  
Karolina Skonieczna-Żydecka
Keyword(s):  
Autism Spectrum Disorders ◽  
Sleep Disorders ◽  
Poor Quality ◽  
Autism Spectrum ◽  
Male Dominance ◽  
Poor Sleep ◽  
Quality Of Sleep ◽  
Tactile Stimuli ◽  
Spectrum Disorders

Individuals with autism spectrum disorders (ASDs) commonly experience problems with the processing of tactile stimuli and poor quality of sleep. The aim of the present study was to analyze whether tactile stimuli modulation (TSM) disorders might be linked to insomnia prevalence in ASD individuals. We hypothesized that sleep disorders in children with ASD may result from improper tactile under/over responsivity. The study included 27 children diagnosed with ASD, aged 6.8 (±2.9 years) with male dominance (n = 22, 81.5%). To evaluate the pattern of TSM we used a clinical interview with a parent, and guided and spontaneous observation of the patients. Sleep disorders were diagnosed using the Athens Insomnia Scale. Of all the children diagnosed with TSM, 20 patients (74.1%) had an over-responsivity pattern and 7 children (25.9%) had an under-responsivity pattern. Of the patients, 11 children (40.7%) met the diagnostic criteria for insomnia. The data indicated a statistical tendency for higher prevalence of insomnia in individuals diagnosed with tactile under-responsivity (p = 0.051). We concluded that under-responsivity toward tactile stimuli may be partly responsible for poor sleep quality in ASD. There is an urgent need to treat sleep and sensory disruptions which may intensify behavioral difficulties in ASD.

scholarly journals Improving Stress Management and Sleep Hygiene in Intelligent Homes

Sensors ◽  
2021 ◽  
Vol 21 (7) ◽  
pp. 2398
Author(s):  
Asterios Leonidis ◽  
Maria Korozi ◽  
Eirini Sykianaki ◽  
Eleni Tsolakou ◽  
Vasilios Kouroumalis ◽  
...  
Keyword(s):  
Sleep Disturbances ◽  
Contextual Information ◽  
High Stress ◽  
Sleep Hygiene ◽  
Poor Sleep ◽  
Health Issues ◽  
Time Data ◽  
Intelligent Home ◽  
And Control

High stress levels and sleep deprivation may cause several mental or physical health issues, such as depression, impaired memory, decreased motivation, obesity, etc. The COVID-19 pandemic has produced unprecedented changes in our lives, generating significant stress, and worries about health, social isolation, employment, and finances. To this end, nowadays more than ever, it is crucial to deliver solutions that can help people to manage and control their stress, as well as to reduce sleep disturbances, so as to improve their health and overall quality of life. Technology, and in particular Ambient Intelligence Environments, can help towards that direction, when considering that they are able to understand the needs of their users, identify their behavior, learn their preferences, and act and react in their interest. This work presents two systems that have been designed and developed in the context of an Intelligent Home, namely CaLmi and HypnOS, which aim to assist users that struggle with stress and poor sleep quality, respectively. Both of the systems rely on real-time data collected by wearable devices, as well as contextual information retrieved from the ambient facilities of the Intelligent Home, so as to offer appropriate pervasive relaxation programs (CaLmi) or provide personalized insights regarding sleep hygiene (HypnOS) to the residents. This article will describe the design process that was followed, the functionality of both systems, the results of the user studies that were conducted for the evaluation of their end-user applications, and a discussion about future plans.

scholarly journals Severe reflux, sleep disturbances, and health-related quality of life after esophageal cancer surgery

2021 ◽  
Author(s):  
Pernilla Lagergren ◽  
Asif Johar ◽  
Helen Rosenlund ◽  
Lars Arnberg ◽  
Lena Haglund ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Disturbances ◽  
Poor Sleep ◽  
Health Related Quality ◽  
Poor Sleep Quality ◽  
Increased Risk ◽  
Related Quality ◽  
Health Related ◽  
Esophagectomy For Cancer

Abstract Purpose Esophagectomy for cancer is an extensive procedure often followed by severe complications. This study investigated whether patients with severe symptoms of reflux are more likely to have sleep disturbances and reduced health-related quality of life (HRQL) after esophagectomy. Methods This Swedish nationwide prospective cohort study encompassed all patients who had undergone esophagectomy for cancer between 2013 and 2018. One year after surgery, the patients responded to three questionnaires on reflux (EORTC QLQOG25), sleep disturbances (KSQ), and HRQL (EORTC QLQ-C30). Multivariable logistic regression provided odds ratios (OR) with 95% confidence intervals (CI) for sleep disturbance/reduced HRQL between patients with and without reflux, adjusted for potential confounders. Results Among 241 esophagectomy patients, 66 (27%) reported severe reflux. Patients with reflux had an increased risk of sleep disturbances (OR 2.3, 95% CI: 1.3–4.3) compared to patients without reflux. More specifically, these patients were more likely to suffer from poor sleep quality (OR 4.9, 95% CI: 1.9–12.4). Patients with reflux and sleep disturbances reported reductions in global quality of life, role function, emotional function, social function, and more symptoms in all scales, except for dyspnea. Conclusions This study suggests that patients with severe symptoms of reflux after esophagectomy have an increased risk of sleep disturbances and poor sleep quality, which in turn are associated with reduced HRQL. Implications for Cancer Survivors Alleviating reflux after oesophageal cancer surgery is important, since this common symptom might reduce HRQL and well-being.

scholarly journals Circadian variation of fatigue in both patients with paralytic poliomyelitis and post-polio syndrome

2013 ◽  
Vol 71 (7) ◽  
pp. 442-445 ◽  
Author(s):  
Celiana Figueiredo Viana ◽  
Márcia Pradella-Hallinan ◽  
Abrahão Augusto Juviniano Quadros ◽  
Luis Fabiano Marin ◽  
Acary Souza Bulle Oliveira
Keyword(s):  
Standard Deviation ◽  
Sleep Disturbances ◽  
Circadian Variation ◽  
Progressive Increase ◽  
Paralytic Poliomyelitis ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Significant Difference ◽  
Sleep Parameters

ObjectiveIt was to evaluate the degree of fatigue in patients with paralytic poliomyelitis (PP) and with post-polio syndrome (PPS), and correlate it with parameters of sleep and the circadian cycle.MethodsThirty patients, 17 female (56.7%), participated in the study: they answered the Revised Piper Fatigue Scale and performed a nocturnal polysomnographic study. Eleven had PP (mean age±standard deviation of 47.9±6.4 years), and 19 had PPS (mean age±standard deviation of 46.4±5.6 years).ResultsOur study showed that fatigue was worse in the afternoon in the PP Group and had a progressive increase throughout the day in the PPS Group. We also observed compromised quality of sleep in both groups, but no statically significant difference was found in the sleep parameters measured by polysomnography.ConclusionFatigue has a well-defined circadian variation, especially in PPS Group. Poor sleep quality is associated with fatigue and, therefore, sleep disturbances should be evaluated and treated in this group of PPS.

scholarly journals Sleep disorders in migraine

2021 ◽  
pp. 111-120
Author(s):  
N. V. Vashchenko ◽  
A. I. Kozhev ◽  
Ju. E. Azimovа
Keyword(s):  
Combination Therapy ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Mutual Influence ◽  
Integrated Approach ◽  
Epidemiological Studies ◽  
Exact Nature ◽  
Obstructive Sleep ◽  
Underlying Mechanisms

Migraine and sleep disorders are common in the general population, may be associated with each other and often significantly reduce patients’ quality of life. Clinicians and epidemiological studies have long acknowledged a link between these conditions. However, the exact nature of this relationship, its underlying mechanisms and patterns are complex and not fully understood. This publication brings together the latest data on the relationship between migraine and sleep disorders: the biochemical and functional-anatomical background, the mutual influence of these conditions on each other and the typical sleep disturbances in migraine patients (such as insomnia, obstructive sleep apnea, parasomnia, snoring, excessive daytime sleepiness). The paper discusses the hypotheses of pathogenetic relationships based on the studies of the central nervous system’s anatomical and physiological features in people with migraine and sleep disorders. The available data should encourage physicians to evaluate sleep quality in migraineurs and use combination therapy systematically. The therapy of insomnia is reviewed: both nonpharmacological and pharmacological therapies are discussed; the advantages of an integrated approach are discussed, and a brief overview of each group of medications is offered.Lastly, a case study of a patient with chronic migraine and insomnia treated with Doxylamine in combination therapy is presented. Treatment with Doxylamine significantly reduced the incidence of insomnia, probably thereby positively influencing the course of migraine as well.

THE STUDY WAS CARRIED OUT TO ASSESS QUALITY OF SLEEP AND PERCEIVED SLEEP DISTRACTORS AMONG PATIENTS ADMITTED AT MMIMS&R HOSPITAL MULLANA AMBALA.

2021 ◽  
pp. 22-26
Author(s):  
Prakash Jha ◽  
Preeti Anand ◽  
Prashant Prashant ◽  
Priya Priya ◽  
Priyanka Roy ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Sampling Technique ◽  
Poor Quality ◽  
Quality Of Sleep ◽  
Early Recovery ◽  
Quality Sleep ◽  
Duration Of Hospitalization ◽  
Education Status ◽  
Assess Quality

A good high-quality of sleep and it's have an effect on in daily existence of both the healthful and sick character turns into one of the most important cognizance of problem. Aims: The study aimed to assess the Quality of Sleep and Perceived Sleep Distractors among patients. Methods: Non-Experimental descriptive research design was conducted among 135 patients through convenient sampling technique. Modied Sleep quality Scale and Structured Perceived Sleep Distractors Perfoma was used. Results: Showed (27.4%) of the patients had poor quality of sleep, most of the patients (47.4%) were having fair quality of sleep. Most of the patients (52.6%) were having severe distractions while sleeping, less than half (44.4%) were having moderate level of distractions while sleeping only (3.0%) perceived very severe distraction during hospital stay. There was a moderate positive relationship between Quality of Sleep and Perceived Sleep Distractors NS Score(r=0.113, p=0.19 ). Further the results also indicated that quality of sleep is only associated with Patient admitted in 2 2 (department) (χ = 30.652, p=0.01) whereas perceived sleep distractors is associated with Education status (χ = 17.280, 2 2 p=0.02), Duration of Hospitalization (χ = 45.425, p=0.00), Patient admitted in (department) (χ = 28.066, p=0.03).Conclusion: The study concludes that there is a need to identify factors responsible that hinders good quality sleep among patients admitted in hospital as well as the sleep quality can be enhanced by decreasing the sleep distractors and thus it can be helpful in the early recovery of the patients

Sleep and Health

2021 ◽  
pp. 17-32
Author(s):  
Andrew S. Tubbs ◽  
Michael A. Grandner
Keyword(s):  
Emotional Health ◽  
The United States ◽  
Mental Illnesses ◽  
Poor Sleep ◽  
Drowsy Driving ◽  
Insufficient Sleep ◽  
Disturbed Sleep ◽  
Risk Of Disease ◽  
Common Problems

Sleep is a core component of human physiology, supporting physical, mental, and emotional health. Unfortunately, insufficient sleep and insomnia are increasingly common problems both in the United States and around the world. Poor sleep is strongly associated with diabetes, obesity, and other cardiometabolic diseases. Pro-inflammatory states associated with disrupted sleep schedules and insufficient sleep are hypothesized as risk factors for cancer. Sleep disturbance impairs cognition and memory, increasing the likelihood of accidents and drowsy driving. Poor sleep is a common and exacerbating feature of many mental illnesses and may impair treatment response. Finally, the burden of insufficient sleep is calculated both in financial costs and increased mortality. Given this evidence, clinicians should recognize and treat disturbed sleep to decrease the risk of disease and improve overall quality of life.

Sleep Epidemiology

2019 ◽  
pp. 11-46
Author(s):  
Susan Redline ◽  
Brian Redline ◽  
Peter James
Keyword(s):  
Sleep Quality ◽  
Quality Index ◽  
Self Report ◽  
Poor Sleep ◽  
Sleep Health ◽  
Sugar Sweetened Beverage ◽  
Social Jetlag ◽  
Obstructive Sleep ◽  
Quality Sleep ◽  
Different Dimensions

This chapter is a primer on sleep epidemiology—the methods of assessment on how sleep is measured (e.g., self-report [such as the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale] vs. with use of objective tools such as actigraphy); validity of sleep measurements; the different dimensions of sleep health and disorders that are of interest (e.g., sleep duration, sleep quality, sleep fragmentation, insomnia, obstructive sleep apnea, social jetlag, snoring, narcolepsy, etc.); general sleep biology and physiology; and why sleep matters (i.e., the epidemiologic consequences of poor sleep health, e.g., connection to other health behaviors and health outcomes such as drug use; sexual risk behaviors; depression; dietary behaviors such as sugar-sweetened beverage consumption; cardiometabolic diseases like obesity, diabetes, and hypertension; and cancer outcomes such as breast cancer).

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