scholarly journals Evaluation of Influenza Vaccination Efficacy: A Universal Epidemic Model

2016 ◽  
Vol 2016 ◽  
pp. 1-8
Author(s):  
Lily Ph. Nizolenko ◽  
Alexander G. Bachinsky ◽  
Sergei I. Bazhan
Keyword(s):  
Influenza Vaccine ◽  
Vaccination Coverage ◽  
Pandemic Influenza ◽  
Epidemic Model ◽  
Seasonal Influenza ◽  
Influenza Epidemic ◽  
Universal Vaccine ◽  
Seasonal Influenza Vaccine ◽  
Pandemic Strains ◽  
Universal Influenza Vaccine

By means of a designed epidemic model, we evaluated the influence of seasonal vaccination coverage as well as a potential universal vaccine with differing efficacy on the aftermath of seasonal and pandemic influenza. The results of the modeling enabled us to conclude that, to control a seasonal influenza epidemic with a reproduction coefficientR0≤1.5, a 35% vaccination coverage with the current seasonal influenza vaccine formulation is sufficient, provided that other epidemiology measures are regularly implemented. IncreasingR0level of pandemic strains will obviously require stronger intervention. In addition, seasonal influenza vaccines fail to confer protection against antigenically distinct pandemic influenza strains. Therefore, the necessity of a universal influenza vaccine is clear. The model predicts that a potential universal vaccine will be able to provide sufficient reliable (90%) protection against pandemic influenza only if its efficacy is comparable with the effectiveness of modern vaccines against seasonal influenza strains (70%–80%); given that at least 40% of the population has been vaccinated in advance, ill individuals have been isolated (observed), and a quarantine has been introduced. If other antiepidemic measures are absent, a vaccination coverage of at least 80% is required.

scholarly journals Influenza Vaccination Coverage among Registered Nurses in China during 2017-2018: an Internet Panel Survey (Preprint)

2019 ◽  
Author(s):  
Zhongjie Li ◽  
Jianxing Yu ◽  
Xiang Ren ◽  
Chuchu Ye ◽  
Keqing Tian ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Registered Nurses ◽  
Vaccination Coverage ◽  
Seasonal Influenza ◽  
Panel Survey ◽  
Vaccine Acceptance ◽  
Seasonal Influenza Vaccine ◽  
Factors Influencing ◽  
Principal Factors

BACKGROUND Influenza vaccination is recommended for nurses in China but is not mandatory or offered free of charge. Identifying factors that impact seasonal influenza vaccine acceptance among nurses in China may inform strategies to increase vaccination coverage in this high priority group. OBJECTIVE To determine influenza vaccination coverage and the principal factors influencing influenza vaccination among nurses in China. METHODS During March 22-April 1, 2018, we conducted an opt-in internet panel survey among registered nurses in China. Respondents were recruited from an internet-based training platform for nurses. We assessed influenza vaccination status and factors influencing influenza vaccine acceptance and refusal. RESULTS Among 22,888 nurses invited to participate, 4,706 responded, and 4,153 were valid respondents. Overall, 257 (6%) nurses reported receiving the seasonal influenza vaccine during the 2017/18 season. Vaccination coverage was highest among nurses working in Beijing (10%, P<.001) and nurses working in primary care (12%, P=.023). The top three reasons for not being vaccinated were lack of time (28%), not knowing where and when to get vaccinated (14%), and lack of confidence in the vaccine’s effectiveness (12%). Overall, 41% of nurses reported experiencing at least one episode of influenza-like illness (ILI) during the 2017/18 season; 87% of nurses kept working while sick, and 25% of nurses reported ever recommending influenza vaccination to patients. Compared with nurses who did not receive influenza vaccination in the 2017/18 season, nurses who received influenza vaccination were more likely to recommend influenza vaccination to patients (67% vs. 22%, P<.001). CONCLUSIONS Influenza vaccination coverage among nurses was low, and only a small proportion recommended influenza vaccine to patients. Our findings highlight the need for a multi-pronged strategy to increase influenza vaccination among nurses in China.

scholarly journals Effectiveness of pandemic and seasonal influenza vaccine in preventing pandemic influenza A(H1N1)2009 infection in England and Scotland 2009-2010

2011 ◽  
Vol 16 (2) ◽  
Author(s):  
P Hardelid ◽  
D M Fleming ◽  
J McMenamin ◽  
N Andrews ◽  
C Robertson ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccine ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Barriers to pandemic influenza vaccination and uptake of seasonal influenza vaccine in the post-pandemic season in Germany

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Merle M Böhmer ◽  
Dietmar Walter ◽  
Gerhard Falkenhorst ◽  
Stephan Müters ◽  
Gérard Krause ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Influenza Vaccination ◽  
Pandemic Influenza ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccine

AF03-adjuvanted and non-adjuvanted pandemic influenza A (H1N1) 2009 vaccines induce strong antibody responses in seasonal influenza vaccine-primed and unprimed mice

Vaccine ◽  
2010 ◽  
Vol 28 (18) ◽  
pp. 3076-3079 ◽  
Author(s):  
Catherine Caillet ◽  
Fabienne Piras ◽  
Marie-Clotilde Bernard ◽  
Aymeric de Montfort ◽  
Florence Boudet ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Seasonal Influenza ◽  
Antibody Responses ◽  
Seasonal Influenza Vaccine ◽  
Influenza A H1n1

scholarly journals Seasonal influenza vaccine dose distribution in 195 countries (2004–2013): Little progress in estimated global vaccination coverage

Vaccine ◽  
2015 ◽  
Vol 33 (42) ◽  
pp. 5598-5605 ◽  
Author(s):  
Abraham Palache ◽  
Valerie Oriol-Mathieu ◽  
Mireli Fino ◽  
Margarita Xydia-Charmanta
Keyword(s):  
Influenza Vaccine ◽  
Vaccination Coverage ◽  
Dose Distribution ◽  
Seasonal Influenza ◽  
Vaccine Dose ◽  
Seasonal Influenza Vaccine

Pandemic influenza A/H1N1 vaccine administered sequentially or simultaneously with seasonal influenza vaccine to HIV-infected children and adolescents

Vaccine ◽  
2011 ◽  
Vol 29 (8) ◽  
pp. 1677-1682 ◽  
Author(s):  
Susanna Esposito ◽  
Laura Tagliaferri ◽  
Cristina Daleno ◽  
Antonia Valzano ◽  
Irene Picciolli ◽  
...  
Keyword(s):  
Influenza Vaccine ◽  
Children And Adolescents ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Seasonal Influenza ◽  
H1n1 Vaccine ◽  
Seasonal Influenza Vaccine ◽  
Influenza A H1n1
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