scholarly journals Electrospun Nanofibers Applications in Dentistry

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Seog-Jin Seo ◽  
Hae-Won Kim ◽  
Jung-Hwan Lee

Nanofibrous structures exhibit many interesting features, such as high surface area and surface functionalization and porosity in the range from submicron to nanoscale, which mimics the natural extracellular matrix. In particular, electrospun nanofibers have gained great attention in the field of tissue engineering due to the ease of fabrication and tailorability in pore size, scaffold shape, and fiber alignment. For the reasons, recently, polymeric nanofibers or bioceramic nanoparticle-incorporated nanofibers have been used in dentistry, and their nanostructure and flexibility have contributed to highly promotive cell homing behaviors, resulting in expecting improved dental regeneration. Here, this paper focuses on recently applied electrospun nanofibers in dentistry in the range from the process to the applications.

2019 ◽  
Vol 14 ◽  
pp. 155892501882490 ◽  
Author(s):  
Fatma Yalcinkaya

The importance of the nanofiber webs increases rapidly due to their highly porous structure, narrow pore size, and distribution; specific surface area and compatibility with inorganics. Electrospinning has been introduced as one of the most efficient technique for the fabrication of polymeric nanofibers due to its ability to fabricate nanostructures with unique properties such as a high surface area and porosity. The process and the operating parameters affect the nanofiber fabrication and the application of nanofibers in various fields, such as sensors, tissue engineering, wound dressing, protective clothes, filtration, desalination, and distillation. In this review, a comprehensive study is presented on the parameters of electrospinning system including applications. More emphasis is given to the application of nanofibers in membrane distillation (MD). The research developments and the current situation of the nanofiber webs in MD are also discussed.


2021 ◽  
Vol 22 (12) ◽  
pp. 6357
Author(s):  
Kinga Halicka ◽  
Joanna Cabaj

Sensors and biosensors have found applications in many areas, e.g., in medicine and clinical diagnostics, or in environmental monitoring. To expand this field, nanotechnology has been employed in the construction of sensing platforms. Because of their properties, such as high surface area to volume ratio, nanofibers (NFs) have been studied and used to develop sensors with higher loading capacity, better sensitivity, and faster response time. They also allow to miniaturize designed platforms. One of the most commonly used techniques of the fabrication of NFs is electrospinning. Electrospun NFs can be used in different types of sensors and biosensors. This review presents recent studies concerning electrospun nanofiber-based electrochemical and optical sensing platforms for the detection of various medically and environmentally relevant compounds, including glucose, drugs, microorganisms, and toxic metal ions.


RSC Advances ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. 3749-3754 ◽  
Author(s):  
Hongri Suo ◽  
Haohong Duan ◽  
Chunping Chen ◽  
Jean-Charles Buffet ◽  
Dermot O'Hare

Core@shell materials which exhibit hierarchical morphology with ultra high surface area and controllable pore size and structure have been synthesised.


2009 ◽  
Vol 610-613 ◽  
pp. 109-113
Author(s):  
Wei Na ◽  
Qi Wei ◽  
Ze Chang Zou ◽  
Zhi Hong Wang ◽  
Qun Yan Li ◽  
...  

Mesoporous silica materials are attractive candidates for enzymes immobilization due to their high surface area, tunable pore size, large pore volume and biocompatibility. In this work, two different enzymes, papain, a small globular enzyme with molecular diameter of 3.6nm, and catalase, a relatively larger enzyme with molecular diameter of 10.4nm were introduced into the pores of siliceous mesostructed cellular foams (MCFs) that had a large cellular pores of 29nm and a small window size of 12nm, respectively. The amount of adsorbed enzymes was found to be dependent on the molecular size of enzymes. The amount of adsorbed catalase was more than two times that of adsorbed papain, suggesting that MCFs with large pores is a suitable host for large enzymes adsorption. The blocking of pores which resulted from aggregation of enzymes in the windows of MCFs and the higher leaching of enzymes form MCFs may be the reason of lower papain adsorption capacity in MCFs.


2021 ◽  
Vol 06 ◽  
Author(s):  
Varun Saxena ◽  
Lalit Pandey ◽  
T. S. Srivatsan

Background: Hydroxyapatite (HAp) is one of the most studied biomimic for biomedical applications. Specially, nano-HAp has been utilized for bone tissue engineering various orthopedic applications. HAp possesses various suitable properties such as bioactivity, biodegradability and cell proliferation efficiency for bone tissue engineering applications. Yet, lacks in self-antibacterial activity, high surface area and target efficiency. Results: In this directioon, researchers have focused on exploring the required surface as well as the inherent properties of HAp at the nanoscale. These properties are largely dependent on the composition, size and morphology of the nano-HAp. Hence, nano-HAp has been found to be an excellent candidate with an attractive combination of properties for selection and use in biomedical applications, those required to enhanced biological responses. Further, depending on the type of application, these factors can be tuned to optimize the performance. Conclusion: In this review article, we focus on the chemical structure of HAp and the routes chosen and used for the synthesis of the nano-HAp. The role of various parameters in controlling synthesis at the nanoscale are presented and briefly discussed. In addition, we provide an overview of the various applications for the pristine and doped nano-HAp with recent examples in areas spanning the following: (i) bone tissue engineering applications, (ii) drug delivery applications, (iii) surface coatings, and (iv) scaffolds. The effect of chemical composition on the mechanical properties, surface properties and biological properties are also highlighted. Nano-HAp is found to be highly proficient for its biomedical applications, especially for bone tissue engineering applications. The nano-sized properties enhances the biological responses. The dopant ions that replaces the Ca ion into the hydroxyapatite (HAp) lattice plays a crucial role in its biomedical applications


1993 ◽  
Vol 8 (12) ◽  
pp. 3100-3105 ◽  
Author(s):  
F-M. Kong ◽  
J.D. LeMay ◽  
S.S. Hulsey ◽  
C.T. Alviso ◽  
R.W. Pekala

Carbon aerogels are synthesized via the aqueous polycondensation of resorcinol with formaldehyde, followed by supercritical drying and subsequent pyrolysis at 1050 °C. As a result of their interconnected porosity, ultrafine cell/pore size, and high surface area, carbon aerogels have many potential applications such as supercapacitors, battery electrodes, catalyst supports, and gas filters. The performance of carbon aerogels in the latter two applications depends on the permeability or gas flow conductance in these materials. By measuring the pressure differential across a thin specimen and the nitrogen gas flow rate in the viscous regime, the permeability of carbon aerogels was calculated from equations based upon Darcy's law. Our measurements show that carbon aerogels have permeabilities on the order of 10−12 to 10−10 cm2 over the density range from 0.05–0.44 g/cm3. Like many other aerogel properties, the permeability of carbon aerogels follows a power law relationship with density, reflecting differences in the average mesopore size. Comparing the results from this study with the permeability of silica aerogels reported by other workers, we found that the permeability of aerogels is governed by a simple universal flow equation. This paper discusses the relationship among permeability, pore size, and density in carbon aerogels.


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