scholarly journals Uncommon Presentation of Isolated Jejunal Lymphoma Masquerading as Crohn’s Disease

2016 ◽  
Vol 2016 ◽  
pp. 1-3
Author(s):  
Swati Sattavan ◽  
Lalit Aggarwal ◽  
Priyadarshi Dikshit

Primary gastrointestinal lymphoma is a rare entity, commonly involving stomach, small bowel, and colorectum. The usual location for small bowel B cell lymphoma is distal ileum due to abundant lymphoid tissue. We are reporting the case of a 53-year-old lady presumptively diagnosed as Crohn’s disease on clinical and radiological grounds but histopathologically proven to be an unusual variant of isolated primary non-Hodgkin’s lymphoma.

2015 ◽  
Vol 65 (4) ◽  
pp. 241 ◽  
Author(s):  
Tae Hyoung Koo ◽  
Won Jong Choi ◽  
Seung Hee Han ◽  
Su Young Kim ◽  
Jong Hun Lee

2019 ◽  
Vol 13 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Koichi Sato ◽  
Tomoaki Suga ◽  
Atsuhiro Hirayama ◽  
Seiichi Daikuhara ◽  
Takeshi Uehara ◽  
...  

2020 ◽  
Vol 13 (4) ◽  
pp. e228818 ◽  
Author(s):  
Adam Joseph Hardy ◽  
Ionica Stoica ◽  
David Edward Kearney ◽  
Diarmuid S O'Riordain

A 62-year-old man presented to our institute with diarrhoea and dysuria on a background of subtotal colectomy and end ileostomy and biological therapy for Crohn’s disease. He was diagnosed with urinary tract infection and acute kidney injury (AKI). Renal ultrasound suggested left hydronephrosis, with renal protocol computed tomography (CT) showing a large pelvic mass. Magnetic resonance imaging (MRI) of the pelvis demonstrated a rectal tumour invading the bladder and compressing both ureters. He underwent cystoscopy, flexible sigmoidoscopy and positron emission tomography–CT and was diagnosed with stage IV non-Hodgkin’s diffuse large B-cell lymphoma. He was treated primarily with rituximab, cyclophosphamide, hydroxydaunomycin, oncovin and prednisolone chemotherapy regimen. He had ongoing urosepsis before admission for pelvic exenteration. He underwent cystoprostatectomy, excision of rectal stump and formation of ileal conduit. Histology showed no signs of residual malignancy. One year later, the patient was admitted to the intensive care unit with aspiration pneumonia, urosepsis and AKI. Despite maximal therapy, he developed multiorgan failure and passed away.


2021 ◽  
Vol 116 (1) ◽  
pp. S1034-S1035
Author(s):  
William D. Davis ◽  
Zaeema Zafar ◽  
Camille H. Boustani ◽  
Tenzin Choden ◽  
Mark C. Mattar

2020 ◽  
Vol 8 (12) ◽  
pp. 3062-3065
Author(s):  
Meriam Sabbah ◽  
Fatma Ben Farhat ◽  
Nawel Bellil ◽  
Fatma Khanchel ◽  
Asma Ouakaa ◽  
...  

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Amal Bennani ◽  
Ghizlane Kharrasse ◽  
Miry Achraf ◽  
Khanoussi Wafa ◽  
Ismaili Zahi ◽  
...  

Abstract Background Lymphoma and dysplasia are rare complications of long-standing Crohn’s disease. We report an exceptional case of a synchronous intestinal marginal zone B-cell lymphoma (MALT lymphoma) and colonic adenoma in a Crohn’s disease patient. Case presentation A 50-year-old male patient presented with right lower quadrant for the last 9 months. He also had associated weight loss and diarrhea alternating with constipation. Ileo-colonoscopy revealed a pseudopolypoid appearance of the colonic and ileal mucosa with many discontinuous ulcerations with a 3 cm sessile polypoid mass at 17 cm from the anal verge. Histological examination of the polypoid lesion revealed an adenoma with high grade dysplasia, while the biopsies of colonic mucosa showed histologic features of Crohn’s disease. Abdominal computed tomography scan (CT scan) and magnetic resonance imaging (MRI) showed circumferential wall thickening of the colon and ileum, enlarged mesenteric lymph nodes and a sessile polypoid mass of the rectosigmoid junction. The patient was scheduled for an ileocoletectomy with resection of the upper rectum and ileorectostomy. The histological examination of the resected segment showed histologic features of Crohn’s disease, a recto-sigmoid polyp with high grade. dysplasia and extensive small lymphocytic infiltrate in both colonic and ileal wall which is strongly stained by CD20 and BCL2. The diagnosis of MALT lymphoma with adenoma on a background of Crohn’s disease was made. The patient successfully completed 8 cycles of Rituximab+ chlorambucil chemotherapy. Nowadays the patient is asymptomatic without evidence of lymphoproliferative recurrence 10 months after surgery. Conclusion We report the first case in the literature of Malt lymphoma with colonic adenoma associated with Crohn’s disease, and discuss his unique macroscopic and histological features in a patient. Without immunosuppressive therapy.


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