scholarly journals Use of NeuroEyeCoach™ to Improve Eye Movement Efficacy in Patients with Homonymous Visual Field Loss

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Arash Sahraie ◽  
Nicola Smania ◽  
Josef Zihl

Visual field deficits are common in patients with damaged retinogeniculostriate pathways. The patient’s eye movements are often affected leading to inefficient visual search. Systematic eye movement training also called compensatory therapy is needed to allow patients to develop effective coping strategies. There is a lack of evidence-based, clinical gold-standard registered medical device accessible to patients at home or in clinical settings and NeuroEyeCoach (NEC) is developed to address this need. In three experiments, we report on performance of patients on NEC compared to the data obtained previously on the earlier versions of the search task (n=32); we assessed whether the self-administered computerised tasks can be used to monitor the progress (n=24) and compared the findings in a subgroup of patients to a healthy control group. Performance on cancellation tasks, simple visual search, and self-reported responses on activities of daily living was compared, before and after training. Patients performed similarly well on NEC as on previous versions of the therapy; the inbuilt functionality for pre- and postevaluation functions was sensitive to allowing assessment of improvements; and improvements in patients were significantly greater than those in a group of healthy adults. In conclusion, NeuroEyeCoach can be used as an effective rehabilitation tool to develop compensatory strategies in patients with visual field deficits after brain injury.

2020 ◽  
pp. 030802262093605
Author(s):  
Christine Hazelton ◽  
Alex Pollock ◽  
Diane Dixon ◽  
Anne Taylor ◽  
Bridget Davis ◽  
...  

Introduction Visual field loss affects around 20% of stroke survivors, reducing quality of life. Eye movement training is a promising rehabilitation method, and several different interventions are used by occupational therapists. This study aimed to explore the feasibility and effects of four eye movement training interventions for stroke survivors with visual field loss. Method A mixed methods study – quantitative n-of-1 with qualitative interviews. The participants were 11 home-dwelling stroke survivors with visual field loss. The interventions used were MyHappyNeuron, NVT, Rainbow Readers and VISIOcoach, delivered in a randomised order. Visual search, reading speed, activities of daily living and quality of life were assessed three times before intervention use, then immediately after each intervention; these were analysed visually. A final semi-structured interview was then analysed using framework methods. Results Evidence of effect was divergent. Quantitatively there was no measured effect, but qualitatively participants reported benefits in visual skills, daily life skills and emotions, which varied by intervention. Median training time was 3–4 hours (range 0.5–6.5) for NVT, Rainbow Readers and MyHappyNeuron, and 9.5 hours (range 2.3–16.8) for VISIOcoach. Conclusion Eye movement training interventions were feasible for stroke survivors at home. Qualitative evidence suggests that variations in the eye movements trained and delivery modality underlie variations in perceived effect.


Biology ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 88
Author(s):  
Anna Baran ◽  
Paulina Kiluk ◽  
Julia Nowowiejska ◽  
Tomasz W. Kaminski ◽  
Magdalena Maciaszek ◽  
...  

Galectin-3 (gal-3) is a multifunctional regulator of various biological processes and diseases, which are common comorbidities in psoriasis. Data regarding potential diagnostic role of gal-3 in psoriasis are insufficient. Serum gal-3 levels were evaluated before and after twelve weeks of treatment with acitretin or methotrexate in 31 patients with plaque-type psoriasis and compared to 11 healthy control group. The mean serum galectin-3 level in patients with psoriasis was significantly higher compared to the control group (p < 0.01). In patients with obesity and long-lasting psoriasis (>20 years) positive relations of gal-3 and PASI were noted. In psoriatics with low gal-3 levels, positive correlations between the gal-3 and BMI, glucose level, and with the latter in short-lasting psoriasis (<20 years) were noted. In the long history of psoriasis, gal-3 was negatively correlated with lipids levels. The Gal-3 level might be a multifaceted modulator of the course of psoriasis and predictive factor of cardiometabolic comorbidities’ development, especially in patients with a long history of the disease or obesity. Patients with low serum gal-3 and short history of psoriasis are presumably at greater risk of diabetes. In patients with long-lasting psoriasis and concomitant obesity, gal-3 may exert a protective role against dyslipidemia or perhaps further CMD development.


2010 ◽  
Vol 9 (8) ◽  
pp. 1210-1210
Author(s):  
L. McIlreavy ◽  
J. Fiser ◽  
P. Bex

2012 ◽  
Vol 3 ◽  
Author(s):  
Emily Wiecek ◽  
Louis R. Pasquale ◽  
Jozsef Fiser ◽  
Steven Dakin ◽  
Peter J. Bex

2009 ◽  
Vol 50 (10) ◽  
pp. 4727 ◽  
Author(s):  
Carlos Gustavo V. De Moraes ◽  
Tiago S. Prata ◽  
Craig A. Liebmann ◽  
Celso Tello ◽  
Robert Ritch ◽  
...  

2003 ◽  
Vol 9 (6) ◽  
pp. 954-959 ◽  
Author(s):  
Åsa Hammar ◽  
Anders Lund ◽  
Kenneth Hugdahl

AbstractAutomatic and effortful information processing in depressed patients was investigated by a visual search paradigm, in order to examine dysfunctional effortful processing in depressed patients. Twenty-one patients with major depression, according to the DSM–IV, and with a moderate depression measured by the Hamilton Rating Scale score at >18 participated in the study. The healthy control group was matched for age, gender, and level of education. Half of the trials involved only one type of distractor, and the other half of the trials involved two types of distractors being presented. The results show that the performance of the depressed patients was equal to the control group when the target was easily recognized with only one type of distractor present. However, when target detection required a more difficult and complex attentive search strategy, effortful information processing, the depressed patients needed longer visual search time compared to the controls. Depressed patients seem to have impaired performance on effortful but not automatic information processing. (JINS, 2003, 9, 954–959.)


1999 ◽  
Vol 13 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Samuel A Zamora ◽  
Robert J Hilsden ◽  
Jon B Meddings ◽  
J Decker Butzner ◽  
R Brent Scott ◽  
...  

BACKGROUND: Members of a subset of first-degree relatives of adults with Crohn’s disease have been shown to have an increased baseline intestinal permeability and/or an exaggerated increase in intestinal permeability after the administration of acetylsalicylic acid.PURPOSE: To determine intestinal permeability in unaffected first-degree relatives of children with Crohn’s disease before and after the administration of an ibuprofen challenge.METHODS: Lactulose-mannitol ratios, a measure of intestinal permeability, were determined in 14 healthy control families (41 subjects) and 14 families with a child with Crohn’s disease (36 relatives, 14 probands) before and after ingestion of ibuprofen. An upper reference limit was defined using the control group as mean ± 2 SD.RESULTS: The proportion of healthy, first-degree relatives with an exaggerated response to ibuprofen (20%, 95% CI 7% to 33%) was significantly higher than controls (P=0.003). The exaggerated response was more common among siblings than among parents of pediatric probands.CONCLUSIONS: Members of a subset of first-degree relatives of children with Crohn’s disease have an exaggerated increase in intestinal permeability after ibuprofen ingestion. These findings are compatible with there being a genetic link between abnormalities of intestinal permeability and Crohn’s disease.


2018 ◽  
Author(s):  
Mathieu Hainselin ◽  
Alexandre Aubry ◽  
Béatrice Bourdin

Improvisational theatre (improv) is supposed to have an impact on cognitive processes (divergent thinking, flexibility, language, memory, problem solving, and co-construction), academic performance, and everyday life in many ways. However, little research studied on the psychological impact of improv, with some results highlighting a divergent thinking enhancement in children and adults, but not with teenagers, one of the most important age groups to practice improv. Therefore, this study aims to assess divergent thinking for middle school students before and after an 11-week session compared to a control group with a sport practice. The Alternative Uses Task was used before and after the session for both groups to evaluate divergent thinking. The improv group had better performance in originality, flexibility and gave less prototypical items after the improv sessions compared to before, while the control group performance was similar before and after. Our results suggest that improv helps teenagers’ divergent thinking to improve, not only with experimental games in the lab context but also after ecological sessions. We urge scientists to study in depth psychological impacts of improvisational theatre and applied improvisation, for a better understanding of improv and as a model to study embodied cognition.


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