scholarly journals Concomitant Prevalence of Low Serum Diamine Oxidase Activity and Carbohydrate Malabsorption

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Dietmar Enko ◽  
Andreas Meinitzer ◽  
Harald Mangge ◽  
Gernot Kriegshäuser ◽  
Gabriele Halwachs-Baumann ◽  
...  
Keyword(s):  
Diamine Oxidase ◽  
Abdominal Discomfort ◽  
Dietary Advice ◽  
Lactose Malabsorption ◽  
Carbohydrate Malabsorption ◽  
Fructose Malabsorption ◽  
Gi Symptoms ◽  
Diamine Oxidase Activity ◽  
Diagnostic Work ◽  
Low Serum

The aim of this retrospective study was to analyze the concomitant prevalence rates for lactose malabsorption (LM), fructose malabsorption (FM), and histamine intolerance (HI) in patients with so far unexplained gastrointestinal (GI) symptoms. A total of 439 outpatients, who presented unclear abdominal discomfort, underwent lactose (50 g) and fructose (25 g) hydrogen (H2) breath tests. Additionally, serum diamine oxidase (DAO) measurements were performed. Individuals with low serum DAO activity (<10 U/mL), GI symptoms, and response to histamine-free diet were diagnosed with HI. Of all 439 patients, 341 (77.7%) were found with 7 various GI conditions. In total, 94 (21.4%), 31 (7.1%), and 100 (22.8%) individuals presented LM, FM, or HI only, whereas 116 (26.4%) patients showed an overlap of GI entities investigated here. Interestingly, 89 out of 241 (36.9%) individuals with carbohydrate malabsorption were also diagnosed with HI (LM + HI: 52 [11.8%], FM + HI: 23 [5.2%], and LM + FM + HI 14 [3.2%] individuals). In conclusion different combinations of LM, FM, and HI are present in individuals with unclear abdominal discomfort/pain. In clinical practice we suggest testing for LM, FM, and additional HI in the diagnostic work-up of these patients. Depending on these various diagnoses possible, patients should get an individualized dietary advice.

Serum diamine oxidase activity is associated with lactose malabsorption phenotypic variation

2017 ◽  
Vol 50 (1-2) ◽  
pp. 50-53 ◽  
Author(s):  
Dietmar Enko ◽  
Gernot Kriegshäuser ◽  
Gabriele Halwachs-Baumann ◽  
Harald Mangge ◽  
Wolfgang J. Schnedl
Keyword(s):  
Phenotypic Variation ◽  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Lactose Malabsorption ◽  
Diamine Oxidase Activity

scholarly journals Roles of Lactose and Fructose Malabsorption and Dietary Outcomes in Children Presenting with Chronic Abdominal Pain

Nutrients ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 3063 ◽  
Author(s):  
Carsten Posovszky ◽  
Vreni Roesler ◽  
Sebastian Becker ◽  
Enno Iven ◽  
Christian Hudert ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Incidental Finding ◽  
Elimination Diet ◽  
Chronic Abdominal Pain ◽  
Functional Abdominal Pain ◽  
Lactose Malabsorption ◽  
Carbohydrate Malabsorption ◽  
Fructose Malabsorption ◽  
Hydrogen Breath Tests ◽  
Carbohydrate Intolerance

Intolerance to lactose or fructose is frequently diagnosed in children with chronic abdominal pain (CAP). However, the causal relationship remains a matter of discussion. A cohort of 253 patients, aged 7–12 years, presenting with unexplained CAP received standardized diagnostics. Additional diagnostic tests were performed based on their medical history and physical and laboratory investigations. Fructose and lactose hydrogen breath tests (H2BT) as well as empiric diagnostic elimination diets were performed in 135 patients reporting abdominal pain related to the consumption of lactose or fructose to evaluate carbohydrate intolerance as a potential cause of CAP. Carbohydrate malabsorption by H2BT was found in 55 (41%) out of 135 patients. An abnormal increase in H2BT was revealed in 30% (35/118) of patients after fructose consumption and in 18% (20/114) of patients after lactose administration. Forty-six percent (25/54) reported pain relief during a diagnostic elimination diet. In total, 17 patients had lactose malabsorption, 29 fructose malabsorption, and nine combined carbohydrate malabsorption. Carbohydrate intolerance as a cause of CAP was diagnosed at follow-up in only 18% (10/55) of patients with malabsorption after the elimination of the respective carbohydrate. Thus, carbohydrate malabsorption appears to be an incidental finding in children with functional abdominal pain disorders, rather than its cause. Therefore, testing of carbohydrate intolerance should only be considered in children with a strong clinical suspicion and with the goal to prevent long-term unnecessary dietary restrictions in children suffering from CAP.

PP165-MON THE INFLUENCE OF MENSTRUAL CYCLE ON SERUM DIAMINE OXIDASE ACTIVITY IN HEALTHY WOMEN

2011 ◽  
Vol 6 (1) ◽  
pp. 176-177
Author(s):  
Y. Hamada ◽  
Y. Shinohara ◽  
M. Yano ◽  
M. Yamamoto ◽  
M. Yoshio ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Healthy Women ◽  
Diamine Oxidase Activity

Intestinal Permeability and Postheparin Plasma Diamine Oxidase Activity in the Prediction of Crohnʼs Disease Relapse

1999 ◽  
Vol 5 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Robert J. Hilsden ◽  
Jon B. Meddings ◽  
James Hardin ◽  
Grant D. Gall ◽  
Lloyd R. Sutherland
Keyword(s):  
Intestinal Permeability ◽  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Disease Relapse ◽  
Diamine Oxidase Activity

Elevated Histaminase (Diamine Oxidase) Activity in Small-Cell Carcinoma of the Lung

1975 ◽  
Vol 293 (25) ◽  
pp. 1286-1290 ◽  
Author(s):  
Stephen B. Baylin ◽  
Martin D. Abeloff ◽  
Kathleen C. Wieman ◽  
J. Walton Tomford ◽  
David S. Ettinger
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Small Cell ◽  
Diamine Oxidase Activity

scholarly journals Relationship between postnatal days, serum Cu concentration and plasma diamine oxidase activity in Japanese Black calves

2020 ◽  
Vol 82 (10) ◽  
pp. 1488-1491
Author(s):  
Tatsuya FUKUDA ◽  
Kenji TSUKANO ◽  
Marina OTSUKA ◽  
Yoshiki MURAKAMI ◽  
Yasuyuki KITADE ◽  
...  
Keyword(s):  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Diamine Oxidase Activity

Regulation of gastric mucosal diamine oxidase activity by gastrin

FEBS Letters ◽  
1992 ◽  
Vol 307 (2) ◽  
pp. 135-138 ◽  
Author(s):  
David M. Hougaard ◽  
Gunnar Houen ◽  
Lars-Inge Larsson
Keyword(s):  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Diamine Oxidase Activity

Diamine oxidase activity in a model of multistep hepatocarcinogenesis

1990 ◽  
Vol 51 (1) ◽  
pp. 75-78 ◽  
Author(s):  
A. Sessa ◽  
M.A. Desiderio ◽  
A. Perin
Keyword(s):  
Oxidase Activity ◽  
Diamine Oxidase ◽  
Diamine Oxidase Activity
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