scholarly journals Multimodality Treatment in Ewing’s Sarcoma Family Tumors of the Maxilla and Maxillary Sinus: Review of the Literature

Sarcoma ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-15 ◽  
Author(s):  
David Thorn ◽  
Christoph Mamot ◽  
Fatime Krasniqi ◽  
Frank Metternich ◽  
Sven Prestin
Keyword(s):  
Soft Tissue ◽  
Maxillary Sinus ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Case Reports ◽  
Neck Region ◽  
Multimodality Treatment ◽  
Malignant Neoplasms ◽  
Review Of The Literature ◽  
Small Series

The Ewing sarcoma family of tumors (ESFT) encompasses a group of highly aggressive, morphologically similar, malignant neoplasms sharing a common spontaneous genetic translocation that affect mostly children and young adults. These predominantly characteristic, small round-cell tumors include Ewing’s sarcoma of the bone and soft tissue, as well as primitive neuroectodermal tumors (PNETs) involving the bone, soft tissue, and thoracopulmonary region (Askin’s tumor). Extraosseous ESFTs are extremely rare, especially in the head and neck region, where literature to date consists of sporadic case reports and very small series. We hereby present a review of the literature published on ESFTs reported in the maxilla and maxillary sinus region from 1968 to 2016.

scholarly journals A Case Report of Urinary Bladder Carcinosarcoma and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Christos Zachariadis ◽  
Ioannis Efthimiou ◽  
Stylianos Giannakopoulos ◽  
Athanasios Bantis ◽  
Alexandra Giatromanolaki ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Urinary Bladder ◽  
Treatment Option ◽  
Transurethral Resection ◽  
Case Reports ◽  
Review Of The Literature ◽  
Small Series ◽  
Radiotherapy Alone ◽  
Aggressive Tumors

Carcinosarcoma of the bladder is an unusual tumour characterized by a combination of malignant epithelial and soft tissue elements. Most of the reported cases have been case reports or small series. Optimal treatment is uncertain. We herein report our experience in such a case treated with transurethral resection followed by radiotherapy with adverse final outcome. Treatment of bladder carcinosarcomas should be aggressive and multimodal but optional treatment is still unknown. Radiotherapy alone is insufficient as a treatment option of these aggressive tumors.

scholarly journals Ewing's sarcoma of the mandible in a young child

2010 ◽  
Vol 21 (1) ◽  
pp. 74-79 ◽  
Author(s):  
Marco Túllio Brazão-Silva ◽  
Alexandre Vieira Fernandes ◽  
Paulo Rogério de Faria ◽  
Sérgio Vitorino Cardoso ◽  
Adriano Mota Loyola
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Neck Region ◽  
Radiographic Examination ◽  
Review Of The Literature ◽  
Head And Neck Region ◽  
Dental Abscess ◽  
Radiolucent Lesion ◽  
Malignant Lesions ◽  
Multiagent Chemotherapy

Ewing's sarcoma (ES) is a malignancy primarily affecting bone tissue that is commonly diagnosed in adolescents and young adults. Its occurrence in the head and neck region is unusual and generally involves the mandible and maxilla. An extensive review of the literature shows only few cases of the oral ES in patients under the age of 5. This paper reports a rare case of ES of the mandible in a 4-year-old girl, which had been previously misdiagnosed and treated as a dental abscess. In the clinical examination, a hard immobile expansive mass of 5 cm in diameter was observed on the left side of the mandible. Radiographic examination revealed a radiolucent lesion with ill-defined borders and wide vestibular bone plate destruction. Microscopically, the tumor was composed by monotonous small round cells that exhibited immunoreactivity for CD99, vimentin and pancytokeratin. The patient was subjected to multiagent chemotherapy with ifosfamide, carboplatin, etoposide, vincristine, cyclophosfamide and doxorrubycin (VAC/ICE regimen). However, after the first chemotherapeutic cycle, the patient died due to disseminated infection. This case elucidates the importance of professional knowledge of the relevant aspects of malignant lesions such as ES.

scholarly journals Ewing's Sarcoma of Maxilla: A Rare Presentation

2015 ◽  
Vol 6 (2) ◽  
pp. 96-98
Author(s):  
Azeem Mohiyuddin ◽  
Ravindra P Deo ◽  
A Sagayaraj ◽  
Divya N jyothi ◽  
Harendra ML Kumar
Keyword(s):  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Neck Region ◽  
Multimodality Treatment ◽  
First Line ◽  
Rare Presentation ◽  
Head And Neck Region ◽  
Jaw Bones ◽  
Rare Site ◽  
Head Neck

ABSTRACT Ewing's sarcoma is a rare malignant small cell tumor occurring in the first and second decades of life and usually involving the long bones of the limb. Literature shows that less than 3% of the tumor originates in the maxillofacial region of which 1% occurs in jaw bones with higher predilection for mandible. Mean age of presentation of this tumor in bones of head and neck region is 10.9 years. Surgery is the first line of treatment and considering the aggressive behavior of the tumor multimodality treatment is preferred to reduce recurrence rate. Due to small number of cases affecting the jaws, there are no definite protocols in treatment of Ewing's sarcoma of maxilla. We are presenting a case of Ewing's sarcoma of maxilla in a 60 years old patient, as it is involving a rare site and has occurred in an uncommon age group. How to cite this article Mohiyuddin SMA, Deo RP, Jyothi DN, Kumar HML, Sagayaraj A. Ewing's Sarcoma of Maxilla: A Rare Presentation. Int J Head Neck Surg 2015;6(2):96-98.

scholarly journals A Rare Neck Mass: Extraskeletal Ewing's Sarcoma

2012 ◽  
Vol 3 (3) ◽  
pp. 165-167
Author(s):  
Mustafa Paksoy ◽  
Gokhan Altin ◽  
Banu Atalay Erdogan ◽  
Ozgur Sekercan ◽  
Fatih Bora ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Head And Neck ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Neck Region ◽  
Neck Mass ◽  
Magnetic Resonance Imaging Examination ◽  
Tissue Mass ◽  
Response To Chemotherapy ◽  
Extraskeletal Ewing’S Sarcoma

ABSTRACT Extraskeletal Ewing's sarcoma (ESS) is rarely found in the head and neck region. This tumor is a rare soft tissue tumor morphologically similar to the Ewing's sarcoma orginating from bone. We report a case of extraskeletal Ewing's sarcoma of the posterior neck region in a 24-year-old woman. Magnetic resonance imaging examination showed a large soft tissue mass in the left paraspinal region. The final diagnosis was extraskeletal Ewing's sarcoma after excision of the mass. The patient showed good response to chemotherapy and radiotherapy. How to cite this article Erdogan BA, Sekercan O, Bora F, Altin G, Paksoy M, Koca SB. A Rare Neck Mass: Extraskeletal Ewing's Sarcoma. Int J Head and Neck Surg 2012;3(3):165-167.

Primary nasal cavity Ewing’s sarcoma in pediatric practice: A clinical case

2021 ◽  
Vol 59 (1) ◽  
pp. 39-42
Author(s):  
А. Bekisheva ◽  
A. Makhneva ◽  
E. Satbaeva ◽  
G. Abyov ◽  
M. Remkulova
Keyword(s):  
Nasal Cavity ◽  
Clinical Case ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Histopathological Examination ◽  
Neck Region ◽  
Diagnostic Techniques ◽  
Tumor Type ◽  
Head And Neck Region ◽  
Tumor Remission

Ewing’s sarcoma is an aggressive tumor rarely found in the head and neck region and extremely rare in the nasal cavity or paranasal sinuses (2-3% of all Ewing’s sarcomas). Purpose: The article presents a clinical diagnostic case of nasal cavity Ewing’s sarcoma finally verified only by IHC test. Results: The presented clinical case describes Ewing’s sarcoma of the nasal cavity in a 14-year-old girl and presents the clinical picture, the results of MRI and CT examination of the sinuses, histopathological and IHC tests. Adequate diagnostical tools made it possible to establish a diagnosis. Timely determined treatment tactics, taking into account the tumor localization and possible postoperative complications, led to tumor remission. At present, the patient is under dynamic observation. Conclusion: The presented clinical case confirms that a primary nasal cavity Ewing’s sarcoma diagnostic largely depends on histopathological examination since visual diagnostic techniques do not provide reliable information on the tumor type.

Infantile intraorbital Ewing’s sarcoma: case report and review of the literature

2020 ◽  
Vol 37 (1) ◽  
pp. 299-304
Author(s):  
Eitaro Ishisaka ◽  
Kenichi Usami ◽  
Chikako Kiyotani ◽  
Keita Terashima ◽  
Hideki Ogiwara
Keyword(s):  
Case Report ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Review Of The Literature

Non Conventional Fractionation in Radiotherapy of the Musculo-Skeletal Sarcomas

1998 ◽  
Vol 84 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Enza Barbieri ◽  
Giovanni Frezza ◽  
Ombretta Martelli ◽  
Stefano Neri ◽  
Mario Mercuri ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Late Effects ◽  
Surgical Complications ◽  
Ewing’S Sarcoma ◽  
Ewing's Sarcoma ◽  
Young Patients ◽  
Soft Tissue Sarcomas ◽  
Treatment Modalities ◽  
Complication Rates ◽  
Bulky Disease

In 1989 we started an accelerated hyperfractionated schedule of radiotherapy (two 1.6 Gy daily fractions) in standard risk localized Ewing's sarcoma of bone, with the aim at reducing late effects in young patients and at improving disease control through a better integration of treatment modalities. From 1991, the same schedule was used in preoperative radiotherapy of adult soft tissue sarcomas of the extremities: the main purpose was to reduce the time to surgery and to evaluate surgical complications in comparison with a previous experience of hypofractionated radiotherapy (one 3 Gy daily fraction). From 1991 to 1997, 76 patients with Ewing's sarcoma and 24 patients with soft tissue sarcoma were treated at our Institution. Results and complication rates are analyzed in comparison with historical data. In Ewing's sarcoma, a correct evaluation of improvement in local control was difficult because of changing treatment policy (bulky disease was not included in the present series). Late effects, as evaluated in patients with a minimum follow-up of 3 years, occurred with similar incidence, but at higher total dose levels in patients treated with accelerated hyperfractionation. In patients with soft tissue sarcomas, incidence of surgical complications is reduced as compared to historical experience. Major problems of wound healing were seen in association with intraoperative brachitherapy boost.

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