scholarly journals Partially Purified Extracts of Sea AnemoneAnemonia viridisAffect the Growth and Viability of Selected Tumour Cell Lines

2016 ◽  
Vol 2016 ◽  
pp. 1-12 ◽  
Author(s):  
Matteo Bulati ◽  
Alessandra Longo ◽  
Tiziana Masullo ◽  
Sara Vlah ◽  
Carmelo Bennici ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Marine Species ◽  
Cancer Cell Lines ◽  
Reversed Phase ◽  
Cytotoxic Effects ◽  
Human Pbmc ◽  
Human Cancer Cell Lines ◽  
Antiproliferative Activities

In the last few years, marine species have been investigated for the presence of natural products with anticancer activity. Using reversed phase chromatography, low molecular weight proteins were fractionated from the sea anemoneAnemonia viridis. Four different fractions were evaluated for their cytotoxic activity by means of erythrocyte haemolysis test, MTS, and LDH assays. Finally, the antiproliferative activities of three of these fractions were studied on PC3, PLC/PRF/5, and A375 human cancer cell lines. Our analysis revealed that the four fractions showed different protein contents and diverse patterns of activity towards human PBMC and cancer cell lines. Interestingly, fractions III and IV exerted cytotoxic effects on human cells. Conversely, fractions I and II displayed very low toxic effects associated with antiproliferative activities on cancer cell lines.

Cytotoxic effects of novel polyoxotungstates and a platinum compound on human cancer cell lines

2005 ◽  
Vol 16 (1) ◽  
pp. 101-106 ◽  
Author(s):  
Hans U. V. Gerth ◽  
Annette Rompel ◽  
Bernt Krebs ◽  
Joachim Boos ◽  
Claudia Lanvers-Kaminsky
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Platinum Compound ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Human Cancer Cell Lines

scholarly journals Antimicrobial and Cytotoxic Effects of Mexican Medicinal Plants

2011 ◽  
Vol 6 (12) ◽  
pp. 1934578X1100601 ◽  
Author(s):  
Maria del Rosario Jacobo-Salcedo ◽  
Angel Josabad Alonso-Castro ◽  
Luis A. Salazar-Olivo ◽  
Candy Carranza-Alvarez ◽  
Luis Ángel González-Espíndola ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Antimicrobial Effects ◽  
Human Cancer Cell Lines ◽  
Guazuma Ulmifolia

The antimicrobial effects of the Mexican medicinal plants Guazuma ulmifolia, Justicia spicigera, Opuntia joconostle, O. leucotricha, Parkinsonia aculeata, Phoradendron longifolium, P. serotinum, Psittacanthus calyculatus, Tecoma stans and Teucrium cubense were tested against several human multi-drug resistant pathogens, including three Gram (+) and five Gram (-) bacterial species and three fungal species using the disk-diffusion assay. The cytotoxicity of plant extracts on human cancer cell lines and human normal non-cancerous cells was also evaluated using the MTT assay. Phoradendron longifolium, Teucrium cubense, Opuntia joconostle, Tecoma stans and Guazuma ulmifolia showed potent antimicrobial effects against at least one multidrug-resistant microorganism (inhibition zone > 15 mm). Only Justicia spicigera and Phoradendron serotinum extracts exerted active cytotoxic effects on human breast cancer cells (IC50≤30 μg/mL). The results showed that Guazuma ulmifolia produced potent antimicrobial effects against Candida albicans and Acinetobacter lwoffii, whereas Justicia spicigera and Phoradendron serotinum exerted the highest toxic effects on MCF-7 and HeLa, respectively, which are human cancer cell lines. These three plant species may be important sources of antimicrobial and cytotoxic agents.

Guaiane sesquiterpenoids fromTorilis japonica and their cytotoxic effects on human cancer cell lines

2006 ◽  
Vol 29 (2) ◽  
pp. 131-134 ◽  
Author(s):  
Hye Won Park ◽  
Sang-Un Choi ◽  
Nam-In Baek ◽  
Sung-Hoon Kim ◽  
Jae Soon Eun ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Human Cancer Cell Lines

Triterpenoids and Steroids from the Fruits ofMelia toosendanand Their Cytotoxic Effects on Two Human Cancer Cell Lines

2010 ◽  
Vol 73 (11) ◽  
pp. 1898-1906 ◽  
Author(s):  
Shi-Biao Wu ◽  
Jing-Jing Su ◽  
Lian-Hui Sun ◽  
Wen-Xuan Wang ◽  
Yun Zhao ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Human Cancer Cell Lines

ChemInform Abstract: Cytotoxic Effects of Quinoxaline Derivatives on Human Cancer Cell Lines.

ChemInform ◽  
2010 ◽  
Vol 30 (8) ◽  
pp. no-no
Author(s):  
H.-W. YOO ◽  
Y.-S. LEE ◽  
M. E. SUH ◽  
D. J. KIM ◽  
S. W. PARK
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Human Cancer Cell Lines ◽  
Quinoxaline Derivatives

scholarly journals Cytotoxic Effects of Topotecan Combined With Various Anticancer Agents in Human Cancer Cell Lines

1996 ◽  
Vol 88 (11) ◽  
pp. 734-741 ◽  
Author(s):  
Scott H. Kaufmann ◽  
David Peereboom ◽  
Christopher A. Buckwalter ◽  
Phyllis A. Svingen ◽  
Louise B. Grochow ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Anticancer Agents ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Cytotoxic Effects ◽  
Human Cancer Cell Lines

Antiproliferative Activities of Parthenolide and Golden Feverfew Extract Against Three Human Cancer Cell Lines

2006 ◽  
Vol 9 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Changqing Wu ◽  
Feng Chen ◽  
James W. Rushing ◽  
Xi Wang ◽  
Hyun-Jin Kim ◽  
...  
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines ◽  
Antiproliferative Activities
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