scholarly journals Evaluation of Round Window Stimulation Performance in Otosclerosis Using Finite Element Modeling

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Shanguo Yang ◽  
Dan Xu ◽  
Xiaole Liu

Round window (RW) stimulation is a new type of middle ear implant’s application for treating patients with middle ear disease, such as otosclerosis. However, clinical outcomes show a substantial degree of variability. One source of variability is the variation in the material properties of the ear components caused by the disease. To investigate the influence of the otosclerosis on the performance of the RW stimulation, a human ear finite element model including middle ear and cochlea was established based on a set of microcomputerized tomography section images of a human temporal bone. Three characteristic changes of the otosclerosis in the auditory system were simulated in the FE model: stapedial annular ligament stiffness enlargement, stapedial abnormal bone growth, and partial fixation of the malleus. The FE model was verified by comparing the model-predicted results with published experimental measurements. The equivalent sound pressure (ESP) of RW stimulation was calculated via comparing the differential intracochlear pressure produced by the RW stimulation and the normal eardrum sound stimulation. The results show that the increase of stapedial annular ligament and partial fixation of the malleus decreases RW stimulation’s ESP prominently at lower frequencies. In contrast, the stapedial abnormal bone growth deteriorates RW stimulation’s ESP severely at higher frequencies.

2015 ◽  
Vol 15 (04) ◽  
pp. 1550048 ◽  
Author(s):  
JIABIN TIAN ◽  
XINSHENG HUANG ◽  
ZHUSHI RAO ◽  
NA TA ◽  
LIFU XU

The finite element (FE) method was used to analyze the effect of coupling conditions between the actuator and the round window membrane (RWM) on the performance of round window (RW) stimulation. A FE model of the human ear consisting of the external ear canal, middle ear and cochlea was firstly developed, and then validation of this model was accomplished through comparison between analytical results and experimental data in the literature. Intracochlear pressure were derived from the model under normal forward sound stimulation and reverse RW stimulation. The equivalent sound pressure of RW stimulation was then calculated via comparing the differential intracochlear pressure produced by the actuator and normal ear canal sound stimulus. The actuator was simulated as a floating mass and placed onto the middle ear cavity side of RWM. Two aspects about the actuator coupling conditions were considered in this study: (1) the cross-section area of the actuator relative to the RWM; (2) the coupling layer between the actuator and the RWM. The results show that smaller actuator size can improve the implant performance of RW stimulation, and size requirements of the actuator can also be reduced by introducing a coupling layer between the actuator and RWM, which will benefit the manufacture of the actuator.


2013 ◽  
Vol 456 ◽  
pp. 576-581 ◽  
Author(s):  
Li Fu Xu ◽  
Na Ta ◽  
Zhu Shi Rao ◽  
Jia Bin Tian

A 2-D finite element model of human cochlea is established in this paper. This model includes the structure of oval window, round window, basilar membrane and cochlear duct which is filled with fluid. The basilar membrane responses are calculated with sound input on the oval window membrane. In order to study the effects of helicotrema on basilar membrane response, three different helicotrema dimensions are set up in the FE model. A two-way fluid-structure interaction numerical method is used to compute the responses in the cochlea. The influence of the helicotrema is acquired and the frequency selectivity of the basilar membrane motion along the cochlear duct is predicted. These results agree with the experiments and indicate much better results are obtained with appropriate helicotrema size.


Author(s):  
Marcus Brown ◽  
John Bradshaw ◽  
Rong Z. Gan

Abstract Blast-induced injuries affect the health of veterans, in which the auditory system is often damaged, and blast-induced auditory damage to the cochlea is difficult to quantify. A recent study modeled blast overpressure (BOP) transmission throughout the ear utilizing a straight, two-chambered cochlea, but the spiral cochlea's response to blast exposure has yet to be investigated. In this study, we utilized a human ear finite element (FE) model with a spiraled, two-chambered cochlea to simulate the response of the anatomical structural cochlea to BOP exposure. The FE model included an ear canal, middle ear, and two and half turns of two-chambered cochlea and simulated a BOP from the ear canal entrance to the spiral cochlea in a transient analysis utilizing fluid-structure interfaces. The model's middle ear was validated with experimental pressure measurements from the outer and middle ear of human temporal bones. The results showed high stapes footplate displacements up to 28.5µm resulting in high intracochlear pressures and basilar membrane (BM) displacements up to 43.2µm from a BOP input of 30.7kPa. The cochlea's spiral shape caused asymmetric pressure distributions as high as 4kPa across the cochlea's width and higher BM transverse motion than that observed in a similar straight cochlea model. The developed spiral cochlea model provides an advancement from the straight cochlea model to increase the understanding of cochlear mechanics during blast and progresses towards a model able to predict potential hearing loss after blast.


Author(s):  
Houguang Liu ◽  
Hu Zhang ◽  
Jianhua Yang ◽  
Xinsheng Huang ◽  
Wen Liu ◽  
...  

As a novel application of implantable middle ear hearing device, round-window stimulation is widely used to treat hearing loss with middle ear disease, such as ossicular chain malformation. To evaluate the influence of ossicular chain malformations on the efficiency of the round-window stimulation, a human ear finite element model, which incorporates cochlear asymmetric structure, was constructed. Five groups of comparison with experimental data confirmed the model’s validity. Based on this model, we investigated the influence of three categories of ossicular chain malformations, that is, incudostapedial disconnection, incus and malleus fixation, and fixation of the stapes. These malformations’ effects were evaluated by comparing the equivalent sound pressures derived from the basilar membrane displacement. Results show that the studied ossicular chain malformations mainly affected the round-window simulation’s performance at low frequencies. In contrast to the fixation of the ossicles, which mainly deteriorates round-window simulation’s low-frequency performance, incudostapedial disconnection increases this performance, especially in the absence of incus process and stapes superstructure. Among the studied ossicular chain malformations, the stapes fixation has a much more severe impact on the round-window stimulation’s efficiency. Thus, the influence of the patients’ ossicular chain malformations should be considered in the design of the round-window stimulation’s actuator. The low-frequency output of the round-window simulation’s actuator should be enhanced, especially for treating the patients with stapes fixation.


Micromachines ◽  
2019 ◽  
Vol 10 (11) ◽  
pp. 782 ◽  
Author(s):  
Liu ◽  
Zhao ◽  
Yang ◽  
Rao

To overcome the inherent deficiencies of hearing aids, implantable middle ear hearing devices (IMEHDs) have emerged as a new treatment for hearing loss. However, clinical results show that the IMEHD performance varies with its transducer’s stimulating site. To numerically analyze the influence of the piezoelectric transducer’s stimulating sites on its hearing compensation performance, we constructed a human ear finite element model and confirmed its validity. Based on this finite element model, the displacement stimulation, which simulates the piezoelectric transducer’s stimulation, was applied to the umbo, the incus long process, the incus body, the stapes, and the round window membrane, respectively. Then, the stimulating site’s effect of the piezoelectric transducer was analyzed by comparing the corresponding displacements of the basilar membrane. Besides, the stimulating site’s sensitivity to the direction of excitation was also studied. The result of the finite element analysis shows that stimulating the incus body is least efficient for the piezoelectric transducer. Meanwhile, stimulating the round window membrane or the stapes generates a higher basilar membrane displacement than stimulating the eardrum or the incus long process. However, the performance of these two ideal sites’ stimulation is sensitive to the changes in the excitation’s direction. Thus, the round window membrane and the stapes is the ideal stimulating sites for the piezoelectric transducer regarding the driving efficiency. The direction of the excitation should be guaranteed for these ideal sites.


2013 ◽  
Vol 419 ◽  
pp. 593-601
Author(s):  
Jia Bin Tian ◽  
Na Ta ◽  
Zhu Shi Rao ◽  
Li Fu Xu ◽  
Xin Sheng Huang

An accurate finite element (FE) model of the human ear can help in understanding the physiological mechanismof human ear and facilitate the design of implantable hearing devices. In this paper,a FE modelof the human ear consisting of the external ear canal, middle ear, and cochlea was developed. The geometry of the external ear canal and middle ear model was based on a fresh specimen of human temporal boneviamicro-computer tomography imaging. A harmonic sound pressure of 90 dB SPL was applied in the ear canal and the multi-field coupled FE analysis was conductedamong the ear canal air, cochlea fluid, and middle ear and cochlea structures. The results were compared with the established physiological data. The satisfactory agreements between the model and published experimental measurementsindicate the middle ear and cochlea functions can be well simulated and further application in terms of human ear can be achieved by the model.


Micromachines ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 40 ◽  
Author(s):  
Houguang Liu ◽  
Hehe Wang ◽  
Zhushi Rao ◽  
Jianhua Yang ◽  
Shanguo Yang

Round window (RW) stimulation is a new application of middle ear implants for treating hearing loss, especially for those with middle ear disease. However, most reports on it are based on the use of the floating mass transducer (FMT), which was not originally designed for round window stimulation. The mismatch of the FMT’s diameter and the round window membrane’s diameter and the uncontrollable preload of the transducer, leads to a high variability in its clinical outcomes. Accordingly, a new piezoelectric transducer for the round-window-stimulating-type middle ear implant is proposed in this paper. The transducer consists of a piezoelectric stack, a flextensional amplifier, a coupling rod, a salver, a plate, a titanium housing and a supporting spring. Based on a constructed coupling finite element model of the human ear and the transducer, the influences of the transducer design parameters on its performance were analyzed. The optimal structure of the supporting spring, which determines the transducer’s resonance frequency, was ascertained. The results demonstrate that our designed transducer generates better output than the FMT, especially at low frequency. Besides this, the power consumption of the transducer was significantly decreased compared with a recently reported RW-stimulating piezoelectric transducer.


Author(s):  
Ashwini Gautam ◽  
Chris Fuller ◽  
James Carneal

This work presents an extensive analysis of the properties of distributed vibration absorbers (DVAs) and their effectiveness in controlling the sound radiation from the base structure. The DVA acts as a distributed mass absorber consisting of a thin metal sheet covering a layer of acoustic foam (porous media) that behaves like a distributed spring-mass-damper system. To assess the effectiveness of these DVAs in controlling the vibration of the base structures (plate) a detailed finite elements model has been developed for the DVA and base plate structure. The foam was modeled as a poroelastic media using 8 node hexahedral elements. The structural (plate) domain was modeled using 16 degree of freedom plate elements. Each of the finite element models have been validated by comparing the numerical results with the available analytical and experimental results. These component models were combined to model the DVA. Preliminary experiments conducted on the DVAs have shown an excellent agreement between the results obtained from the numerical model of the DVA and from the experiments. The component models and the DVA model were then combined into a larger FE model comprised of a base plate with the DVA treatment on its surface. The results from the simulation of this numerical model have shown that there has been a significant reduction in the vibration levels of the base plate due to DVA treatment on it. It has been shown from this work that the inclusion of the DVAs on the base plate reduces their vibration response and therefore the radiated noise. Moreover, the detailed development of the finite element model for the foam has provided us with the capability to analyze the physics behind the behavior of the distributed vibration absorbers (DVAs) and to develop more optimized designs for the same.


Author(s):  
J. Rodriguez ◽  
M. Him

Abstract This paper presents a finite element mesh generation algorithm (PREPAT) designed to automatically discretize two-dimensional domains. The mesh generation algorithm is a mapping scheme which creates a uniform isoparametric FE model based on a pre-partitioned domain of the component. The proposed algorithm provides a faster and more accurate tool in the pre-processing phase of a Finite Element Analysis (FEA). A primary goal of the developed mesh generator is to create a finite element model requiring only essential input from the analyst. As a result, the generator code utilizes only a sketch, based on geometric primitives, and information relating to loading/boundary conditions. These conditions represents the constraints that are propagated throughout the model and the available finite elements are uniformly mapped in the resulting sub-domains. Relative advantages and limitations of the mesh generator are discussed. Examples are presented to illustrate the accuracy, efficiency and applicability of PREPAT.


2017 ◽  
Vol 11 (1) ◽  
pp. 1026-1035 ◽  
Author(s):  
Ahmad Basshofi Habieb ◽  
Gabriele Milani ◽  
Tavio Tavio ◽  
Federico Milani

Introduction:An advanced Finite Element model is presented to examine the performance of a low-cost friction based-isolation system in reducing the seismic vulnerability of low-class rural housings. This study, which is mainly numerical, adopts as benchmark an experimental investigation on a single story masonry system eventually isolated at the base and tested on a shaking table in India.Methods:Four friction isolation interfaces, namely, marble-marble, marble-high-density polyethylene, marble-rubber sheet, and marble-geosynthetic were involved. Those interfaces differ for the friction coefficient, which was experimentally obtained through the aforementioned research. The FE model adopted here is based on a macroscopic approach for masonry, which is assumed as an isotropic material exhibiting damage and softening. The Concrete damage plasticity (CDP) model, that is available in standard package of ABAQUS finite element software, is used to determine the non-linear behavior of the house under non-linear dynamic excitation.Results and Conclusion:The results of FE analyses show that the utilization of friction isolation systems could much decrease the acceleration response at roof level, with a very good agreement with the experimental data. It is also found that systems with marble-marble and marble-geosynthetic interfaces reduce the roof acceleration up to 50% comparing to the system without isolation. Another interesting result is that there was little damage appearing in systems with frictional isolation during numerical simulations. Meanwhile, a severe state of damage was clearly visible for the system without isolation.


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