scholarly journals The Protective Effects of Buzui on Acute Alcoholism in Mice

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Chen Chen ◽  
Da-Chao Wen ◽  
Shu-di Gao ◽  
Xiao-yu Hu ◽  
Cheng Yi

This study was designed to investigate the role of a traditional buzui recipe in anti-inebriation treatment. Buzui consists of Fructus Schisandrae Chinensis, Fructus Chebulae, Fructus Mume, Fructus Crataegi, Endothelium Corneum Gigeriae Galli, and Excrementum Bombycis. The buzui mixture was delivered by gavage, and ethanol was delivered subsequent to the final treatment. The effects of buzui on the righting reflex, inebriation rates, and the survival curve are depicted. Blood alcohol concentrations, alanine aminotransferase (ALT) levels, aspartate aminotransferase (AST) levels, and alkaline phosphatase (ALP) levels were recorded. The activities of alcohol dehydrogenase (ADH), aldehyde dehydrogenase (ALDH), and superoxide dismutase (SOD), as well as malonaldehyde (MDA) levels, were also measured. Our results demonstrated that a traditional buzui recipe showed significant effects on promoting wakefulness and the prevention of acute alcohol intoxication, accelerating the metabolism of alcohol in the liver and reducing the oxidative damage caused by acute alcoholism.

1995 ◽  
Vol 19 (3) ◽  
pp. 759-762 ◽  
Author(s):  
Hanna Taivainen ◽  
Kalevi Laitinen ◽  
Riitta Tahtela ◽  
Kalervo Kiianmaa ◽  
Matti J. Valimaki

PEDIATRICS ◽  
1970 ◽  
Vol 46 (3) ◽  
pp. 445-447
Author(s):  
Malcolm H. Moss

The inhalation of ethyl or isopropylalcohol vapor during sponge bathing may result in alcohol intoxication and coma. Ingestion of these alcohols may cause hypoglycemia in children or adults. The present case is the first reported in which alcohol-induced hypoglycemia developed following inhalation of alcohol. A six month-old male infant became comatose following sponge bathing with ethyl alcohol. He was found to have acute alcohol intoxication (blood alcohol 220 mg per 100 ml) and severe hypoglycemia (blood glucose 22 mg per 100 ml). The administration of 50% glucose in water intravenously resulted in prompt recovery. Alcohol sponging to lower elevated temperature is rarely necessary. Cooling with tepid water is effective and considerably less hazardous; the addition of alcohol is not necessary.


1954 ◽  
Vol 32 (4) ◽  
pp. 465-469 ◽  
Author(s):  
E. J. Masoro ◽  
Henry Abramovitch

The role of insulin in ethanol metabolism was investigated with the aid of C14-labeled ethanol. Surviving kidney and liver slices prepared from insulized rats oxidized ethanol to carbon dioxide at approximately the same rate as slices prepared from control rats. The data on the effect of insulin on the conversion of ethanol to lipids are equivocal since the P value is 0.036. There appears to be some increase in lipogenesis but not of an appreciable magnitude. The possibility that the beneficial effects noted in the treatment of acute alcohol intoxication with insulin may be the result of an increased synthetic metabolism is discussed.


2016 ◽  
Vol 176 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Bettina Grüne ◽  
Daniela Piontek ◽  
Oliver Pogarell ◽  
Armin Grübl ◽  
Cornelius Groß ◽  
...  

2005 ◽  
Vol 31 (6) ◽  
pp. 1301-1309 ◽  
Author(s):  
Tom A Schweizer ◽  
Muriel Vogel-Sprott ◽  
James Danckert ◽  
Eric A Roy ◽  
Amanda Skakum ◽  
...  

2012 ◽  
Vol 31 (3) ◽  
pp. 208-213 ◽  
Author(s):  
Kazim Kartkaya ◽  
Ayşegül Oğlakçı ◽  
Hakan Şentürk ◽  
Gökhan Bayramoğlu ◽  
Mediha Canbek ◽  
...  

1954 ◽  
Vol 32 (1) ◽  
pp. 465-469 ◽  
Author(s):  
E. J. Masoro ◽  
Henry Abramovitch

The role of insulin in ethanol metabolism was investigated with the aid of C14-labeled ethanol. Surviving kidney and liver slices prepared from insulized rats oxidized ethanol to carbon dioxide at approximately the same rate as slices prepared from control rats. The data on the effect of insulin on the conversion of ethanol to lipids are equivocal since the P value is 0.036. There appears to be some increase in lipogenesis but not of an appreciable magnitude. The possibility that the beneficial effects noted in the treatment of acute alcohol intoxication with insulin may be the result of an increased synthetic metabolism is discussed.


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