scholarly journals Effect of Cycloplegia on Keratometric and Biometric Parameters in Keratoconus

2016 ◽  
Vol 2016 ◽  
pp. 1-6
Author(s):  
Nihat Polat ◽  
Abuzer Gunduz

Purpose.To obtain information about effect of cycloplegia on keratometry and biometry in keratoconus.Methods.48 keratoconus (Group 1) and 52 healthy subjects (Group 2) were included in the study. We measured the flat meridian of the anterior corneal surface (K1), steep meridian of the anterior corneal surface (K2), lens thickness (LT), anterior chamber depth (ACD), and axial length (AL) using the Lenstar LS 900 before and after cycloplegia.Results.The median K1 in Group 1 was 45.64 D before and 45.42 D after cycloplegia, and the difference was statistically significant (P<0.05). The median K2 in Group 1 was 50.96 D before and 50.17 D after cycloplegia, and the difference was significant (P<0.05). The median K1 and K2 in Group 2 were 42.84 and 44.49 D, respectively, before cycloplegia, and 42.84 and 44.56 D after cycloplegia, and the differences were not statistically significant (allP>0.05). There were significant differences in SE, LT, ACD, and RLP between before and after cycloplegia in either Group 1 (allP<0.05) or Group 2 (allP<0.05). There were not statistically significant differences in AL between before cycloplegia and after cycloplegia in either Group 1 (P=0.533) or group 2 (P=0.529).Conclusions.Flattened corneal curvature and increase in ACD following cycloplegia in keratoconus patients were detected.

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Emrullah Beyazyıldız ◽  
Özlem Beyazyıldız ◽  
Süleyman Günaydın ◽  
Emrah Kan ◽  
Mert Şimşek ◽  
...  

Purpose. To evaluate optical low coherence reflectometry (OLCR) parameters in patients with exfoliation syndrome (EXS) undergoing cataract surgery.Methods. Forty-seven eyes of 47 patients with EXS (Group 1), and 55 eyes of 55 healthy subjects (Group 2) were included in the study. Anterior chamber depth (ACD), lens thickness (LT), axial length (AL), central corneal thickness (CCT), horizontal corneal length (HCL), and pupil diameter (PD) parameters were measured by OLCR (Lenstar LS 900, Haag-Streit) and compared between groups. Shapiro-Wilk test and Mann WhitneyUtests were used for statistical analyses.Results. The mean ACD, HCL, and PD values were significantly lower in EXS group than in healthy subjects (P= 0.01,P= 0.04, andP<0.001, resp.). The mean LT was significantly higher in EXS group than in healthy subjects (P= 0.007). There was no significant difference between groups in means of AXL and CCT.Conclusions. According to OLCR measures, eyes with EXS have shallower ACD, smaller PD, thicker LT, shorter HCL, and no significantly different CCT levels.


2021 ◽  
Vol 50 (10) ◽  
pp. 3077-3084
Author(s):  
Mohd Izzuddin Hairol ◽  
Norlaili Arif ◽  
Pui Theng Yong ◽  
Mariah Asem Shehadeh Saleh Ali ◽  
Nik Nor Adlina Nik Idris ◽  
...  

Axial length of the eye correlates with the magnitude of myopia. However, there are conflicting reports on the relationship between certain corneal parameters with myopia magnitude. The objective of this study was to compare ocular biometry and corneal parameters between emmetropic and myopic groups. Participants (n=127) were categorized as emmetropia (spherical equivalent, SE, ±0.50D), low myopia (-0.75D≤SE<-6.00D) and high myopia (SE≥-6.00D). The difference in axial length, anterior chamber depth, and vitreous chamber depth between emmetrope, low myope, and high myope were highly significant (one-way ANOVA, all p<0.001) with significant correlations between SE and all these parameters (simple regressions, all p<0.001). However, central corneal thickness, corneal radius of curvature, and corneal asphericity between these groups, and the correlations between the ocular parameters with SE were not significantly different (all p>0.05). Corneal curvature correlated significantly with axial length (p=0.001) but not with myopia magnitude (p=0.91). Rather than myopia magnitude, axial length appears to be more sensitive to detect changes in corneal curvature in myopes. In conclusion, myopic patients’ axial length should be carefully considered for interventions that involve the cornea, such as orthokeratology and refractive surgery.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 2545-2545
Author(s):  
Ivan A. Popov ◽  
Oleg I. Kit ◽  
Alla I. Shikhlyarova ◽  
Elena M. Frantsiyants ◽  
Eduard E. Rostorguev ◽  
...  

2545 Background: The standard treatment of malignant brain gliomas, including surgical and radiation therapies, does not provide recovery and a long-time favorable prognosis. The development of technologies and international guidelines on the introduction of electric (TTF) and electromagnetic (TMS) fields in combination treatment for glioblastomas aims to improve immediate results, as shown in experiments on human glioblastoma cell culture. The TMS protocol requires further refinement in parameters of frequency, intensity, and exposure with an assessment of the immediate results of combined treatment. Methods: The study included 60 patients diagnosed with MBG receiving osteoplastic craniotomy with radical (within visible unchanged tissues) tumor removal. Starting from the second day after the surgery, patients of group 1 (n = 30) received 10 sessions of magnetotherapy in the double exposure mode. For the first morning exposure, we used an ultra-low-frequency magnetic field (ULFMF) (0.03 to 9.0 Hz) on the hypothalamus projection area to induce a general antistress reaction. After 2.5-3 hours, local (on the surgical site) TMS exposure with the Neuro-MSD system (Russia) was applied in the pulse algorithm, up to 1 GHz and 5 Hz, 15 mT, 3 min. The induction was reduced exponentially (C = 0.8). The control group 2 (n = 30) did not receive ULFMF or TMS. Magnetic resonance imaging (MRI) was used to determine the volume of tumors (Vt, cm3) and perifocal edema (Ve, cm3) calculated according to the Shrek’s formula for an ellipsoid (V = a×b×c×π/6). Results: Before surgery, Vt = 54.7±5.7cm3 in group 1, in group 2 - Vt = 60.9±8.5cm3 (no statistical differences). After surgery and the subsequent course of ULFMF and TMS, residual tumor volumes in group 1 were 2.5 times lower than in controls (p < 0.05). The difference between Ve values before and after treatment was on average 80.7 cm3 in group 1 and 41.8 cm3 in group 2 (p < 0.05). Conclusions: The inclusion of sequential ULFMF and TMS exposures into postoperative therapy for gliomas, taking into account various vectors of the influence on the projection of centers of homeostasis regulation and the surgical field, as well as the development of programmed modes of biotropic exposure parameters, improves antitumor and anti-edematous effects.


Author(s):  
I Kadek Arya Gangga Permana ◽  
Putu Astawa ◽  
Desak Made Wihandani ◽  
Ketut Tirtayasa ◽  
I Made Jawi ◽  
...  

ABSTRACTIntroduction: The objective of a basketball game is to insert the ball into the opponent's basket and keep our basket alone so as not to concede the ball. This becomes important because it determines points to improve the ability and maximize points in the game so this needs to be trained. Free throw shots can be done using one hand or two hands. Whereas a free throw is a shot given to a player for committing an offense. This shot is done in the exact position behind the line of free shots in accordance with the rules. Purpose:This study aims to compare training model 1 (beef concept with push up and jogging) and training model 2 (beef concept with dumble and jogging) to improve the accuracy of free throw shooting.This research was conducted on 40 students of SMP Negeri 1 Kuta Selatan who were chosen in simple random which has fulfilled inclusion and exclusion criteria. The sample was divided into two groups so that each group was 20 people and given different treatment for six weeks. Group 1 was given model 1 training and Group 2 was given a model 2 training. Methods:The data obtained were analyzed by paired t- test to find the difference between before and after training in both groups and t-independent test to find the difference of shooting free throw accuracy between groups both before and after the training. The meaning limit is 0.05. The research design used is experimental design Randomized Pre and Post test Group Design. According to Pocock's (2008) theory, each group consisted of 20 groups of 1 and group 2. All groups were given preliminary tests, between treatment one and two treatment were given concurrent training, then each treatment was observed.Results:The result showed that the accuracy of free throw shooting between groups after training was 3.85 ± 1.09 in group 1 and in group 2 was 2.90 ± 1.12. The average accuracy of free throw shooting in training model 1 was higher than with model 2 training which was statistically significantly different with p = 0,010 (p <0,05).Conclution:From the results of this study it is concluded that the training of model 1 further improves the accuracy of free throw shooting rather than training model 2, Suggestion: in practice it is suggested to use training model 1 to improve the accuracy of free throw shooting. Keywords: beef concept, push up, jogging, dumble, free throw shooting


2016 ◽  
Vol 06 (03) ◽  
pp. 16-20
Author(s):  
Muralee Mohan ◽  
B. Rajendra Prasad ◽  
S. M. Sharma ◽  
Tripthi Shetty ◽  
Ashay Shah

AbstractHypertrophic scarring following surgical procedures & trauma are a great concern for patients and a challenging problem for clinicians. The therapeutic management of hypertrophic scars is a problem that has not yet been satisfactorily solved. Contractubex® ointment and intra lesional injection of corticosteroids have been used effectively for treatment and prevention of hypertrophic scars. However very few data is available to determine the efficacy of Contractubex® ointment and intra lesional injection of corticosteroids for the treatment of hypertrophic scar. Two study groups were made with 10 patients in each group. Patients in Group 1 treated with Contractubex® and patients in Group 2 treated with intra lesional corticosteroid (Triamcinolone acetonide). Scar was analyzed with Vancouver Scar Scale (VSS) at 2 weeks, 6 weeks and 12 weeks. The collected data was statistically analyzed. We found that the difference between before and after treatment scores for each of the groups was statistically significant (p < 0.05). The mean of the before and after treatment difference for the Group 1 (Contractubex® ) was 4.7 while that of group 2 (Corticosteroids) was 2.8. This demonstrated a significant superiority of the Contractubex® treatment compared to corticosteroid treatment. The difference between treatment responses for both the groups was statistically significant (p < 0.05). Excellent to good responses were reported in 90% of the Group 1 (Contractubex®) patients and 30% of Group 2 (Corticosteroids).


2017 ◽  
Vol 95 (9) ◽  
pp. 817-823
Author(s):  
Olesya A. Rubanenko ◽  
O. V. Fatenkov ◽  
S. M. Khokhlunov ◽  
A. P. Semagin ◽  
D. V. Kuznetsov ◽  
...  

Aim. To evaluate the influence of combination of omega-3 polyunsaturated fatty acids and atorvastatin on the risk of atrial fibrillation (AF) after coronary bypass surgery (CBS). Material and methods. The study included 114 patients divided into 2 groups, one comprised of 59 ones (75,6% men of mean age 62,0±7,3 yr given conventional medication), the other including 55 patients (80,0% men of mean age 59,4±6,7 yr given omega-3 polyunsaturated fatty acids 5 days before (2 g/d) and during 3 weeks after CBS (1 g/d)). All patients were treated with atorvastatin at the outpatient stage. IL-6,8, 10 and C-reactive protein (CRP), fibrinogen, troponin, NT-proBNP, superoxide dismutase (SOD), and myeloperoxidase were measured at admittance and on day 3.7±1.4 after surgery. Results. AF developed on day 5.9±4.9 (mean) after surgery. Patients of group 2 tended to have fewer new episodes of arrhythmia although no significant difference between the groups was documented (9,1% vs 18,6%, р=0,12). Group 2 included more smokers (74,5% vs 45,8%, р=0,002) and patients with atherosclerosis of lower limb arteries (87,3% vs 71,2%, р=0,03) but fewer those consuming nitrates (39,0% vs 18,2%, р=0,01) and Ca antagonists (45,8% vs 21,8%, р=0,006).Mean dose of atorvastatin given to patients of groups 1 and 2 was 24.7±12.5 and 25.1±10.5 mg/d respectively (р=0,2), duration of its intake 14.6±12.7 and 21.5±19.3 months (р<0,001). There. was no significant difference between leukocyte count, leukogram, IL-8, IL-10, NT-proBNP, and troponin levels before and after CBS. Surgical myocardial revascularization caused a rise in leukocyte count, shifted the leukogram toward predominance of stab and segmented cells, increased IL-8, IL-10, fibrinogen, NT-proBNP, CRP, and troponin levels in both groups. IL-8 and IL-10 levels remained normal before and after surgery. Preoperative IL-6 level in group 1 was significantly higher than in group 2 (21,7±13,0 vs 2.5±2,2 pg/ml, р<0,001). Postoperatively, the difference was absent. The CRP level before surgery was high in both groups (3122.7±2175.8 vs 3670.8±2490.0 U/g) but decreased after CBS although remained higher in group 1 (1957.6±1660.3 vs 1069.8±630.2 U/g, р<0,001). Myeloperoxidase level increased postoperatively in both groups but the difference was insignificant. Fibrinogen and CRP in the postoperative period increased more significantly in group 2 than in group 1 (4,9±1,4 vs 4,4±1,1 g/l, р=0,02 and 8,6±2,2 vs 5,4±2,3 mg/l respectively, р<0,001). Conclusion. The study revealed an insignificant decrease in the number of AF episodes in the early post-CDS period in patients treated with omega-3 polyunsaturated fatty acids and atorvastatin compared with those given the latter medication alone. Also, fibrinogen and CRP levels as markers of inflammation increased while SOD antioxidative activity decreased.


2020 ◽  
Vol 82 (2) ◽  
pp. 41-49
Author(s):  
Mhamed OUZZANI ◽  
Catherine Johanna Wright ◽  
Luigina Sorbara

Purpose: The purpose of this study was to retrospectively examine data from patients who had undergone orthokeratology (OK) to quantify the amount of mid-perpheral steeping in tangential curvature (MP-TC) and total refractive power (TRP) changes. Methods: Charts were reviewed from participants and data from the Pentacam instrument were collected prior to OK and after the final visit. Variables included central flattening (C-TC), the e-value, the mid-peripheral tangential curvatures (MP-TC), total corneal refractive power (TRP), the initial Rx (sphere) and initial corneal curvature (flat K). The group was further subdivided into high and low myopia for comparison. All participants were fitted with the Paragon CRT lenses. Data analysis was conducted to analyse the effects of lenses on TC and TRP. Results: A total of 40 patients (80 eyes) age13.95±6.80, 34 M and 46 F, were successfully fitted with CRT lenses. The average sphere was -4.23±0.90D for Group 1 and -1.89±0.62D for Group 2 The changes in TC and TRP from baseline were significant (both P<0.0001). The difference between the amount of C-TC and the maximum area of MPTC was ≈4.00D in the horizontal meridian and ≈3.00 in the veritcal meridian. The amount of MP-TC change from baseline was ≈2.00D in both meridians. There was a similar change in TRP: the distance from the centre to mid-periphery ≈2.50D. For C-TC, C-TRP, MP-TC, MP-TRP there was no significant difference between the 2 groups, overall (P=0.541 (TC) and P=0.321(TRP)). Conclusion: Results from this study should provide valuable insights into the topographic and refractive changes occurring with orthokeratology.


2017 ◽  
Vol 11 (1) ◽  
pp. 152-155 ◽  
Author(s):  
Ozlem Barut Selver ◽  
Melis Palamar ◽  
Kevser Gerceker ◽  
Sait Egrilmez ◽  
Ayse Yagci

Objective: It is aimed to determine whether fasting during Ramadan has any significant effect on anterior chamber parameters, visual acuity and intraocular pressures. Methods: 31 fasting (Group 1) and 30 non-fasting healthy volunteers (Group 2) were enrolled. All cases underwent an ophthalmological examination and anterior segment parameter evaluation (central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pupil size) with Pentacam before and after the breaking of the Ramadan fast in Group 1, before and after dinner in Group 2. Results: The mean age was 43.35 ± 13.20 in Group 1, 43.17 ± 12.90 in Group 2 (p= 0.955). No significant difference was detected in any of the parameters in both groups. Conclusion: There is a need for more detailed and associated studies to understand better about the influence of Ramadan fast on various ocular parameters.


2018 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Gede Denny Wiradarma ◽  
Anak Ayu Nyoman Trisna Narta Dewi ◽  
I Gusti Ayu Artini

Agility is a form of exercise with fast movement and changing direction and agile. Seeing the many agility exercises targeting the coordination of muscle nerves, reaction speed, balance, muscle strength alone but did not increase flexibility significantly. This study aims to determine the comparison of agility ladder exercise lateral run method with circuit training in terms of increased agility. The research design with experimental Pre-Test and Post- Test Two Group Design, sample of 18 people divided into 2 groups with simple random sampling. The sample of this research is futsal team player Griya Tansa Trisna Dalung. Group 1 was given Agility Ladder Exercise Lateral Run method and group 2 was given Circuit Training, research for 5 weeks with dose of exercise 3 times in one week. Illinois Agility run test used before and after training to measure agility. Normality test using Saphiro Wilk, homogeneity using Levene's test and hypothesis testing using Independent T-test. The data mean group 1 and group 2 were normal and homogeneous distributed with mean increase in group 1 was 2.89 and group 2 was 4.47. Difference between group 1 and group 2 was obtained p = 0,000 (p <0,05) meaning statistically significant difference.This research concludes circuit training exercises more effective are used to improve agility on the team's futsal player Griya Tansa Trisna Dalung. Keywords: agility, agility ladder exercise, lateral run method, circuit training


Author(s):  
Dhanush H. C. ◽  
Santosh Malashetti ◽  
Chandrashekharayya S. H. ◽  
Prabhu Khavasi

<p><strong>Background: </strong>Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure due to an IgE-mediated inflammation of membranes lining the nose. Allergic rhinitis is subdivided into intermittent (IAR) or persistent (PER) disease and the severity into mild or moderate/severe. The most widely used and effective medications to treat allergic rhinitis are oral or topical antihistamines and topical nasal steroids.</p><p><strong>Methods: </strong>This prospective case series study included 80 patients of PER divided randomly in to 2 groups of 40 each with group 1 receiving fluticasone propionate and azelastine and group 2 receiving fluticasone propionate alone. Individual symptom scores and total symptom score (TSS) were recorded before treatment and after 4 weeks of treatment.</p><p><strong>Results: </strong><strong> </strong>The difference in mean TSS before and after 4 weeks study period were statistically significant in both groups (p&lt;0.01 in both). Group 1 had TSS of 1.525±1.06 and group 2 had TSS of 3.275±1.75 after 4 weeks of treatment and the difference between them was statistically significant (p&lt;0.01).</p><p><strong>Conclusions: </strong>In allergic rhinitis, both fluticasone propionate + azelastine nasal spray and fluticasone propionate nasal spray are effective in relieving symptoms. But, fluticasone propionate and azelastine has significant reduction of symptoms when compared with fluticasone propionate alone.</p>


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