scholarly journals The Use of Lidocaine and Bupivacaine Mix in Adult Safe Male Circumcision: Less Is More

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
M. Galukande ◽  
S. Hodges ◽  
K. Duffy ◽  
A. Coutinho ◽  
S. Kaggwa

Introduction. Lignocaine is (with or without bupivacaine) the only drug recommended for local anesthesia for safe adult male circumcision (SMC). This study evaluated the effectiveness of postoperative pain control when using two different concentrations. Methods. An observational analytical study conducted at an urban high volume site. Pain was assessed using the Visual Analogue Scale. Mixtures of lignocaine 2%, bupivacaine 0.5% (LiB), and water in ratios of 4 : 4 : 2 and 3 : 3 : 4 were compared. Results. Data from 217 clients were analyzed: 100 in the 4 : 4 : 2 group and 117 in the 3 : 3 : 4 group. Clients in the 4 : 4 : 2 group had more pain, at 60 minutes, compared to the 3 : 3 : 4 group (p=0.035). The 3 : 3 : 4 mix used 70% less lignocaine and 90% less bupivacaine (60 mg and 15 mg); the allowable maximum dosages are 200 mg and 150 mg, respectively. Conclusion. The 3 : 3 : 4 mix was superior to the 4 : 4 : 2 mix. This has implications for supply chain management and potential reduction of LA toxicity. We therefore recommend the 3 : 3 : 4 mix for routine adult SMC.

2009 ◽  
Vol 12 (Number 1) ◽  
pp. 19-22
Author(s):  
S Alam ◽  
A K M Shamsuddin ◽  
Md. W Abusaleh ◽  
A H Khan

Inadequate postoperative pain control causes significant morbidity and mortality. ht the presets mum in the paediatric surgery department the effective pain control is am mandardkert For this reason this study was undertaken to find out the degree of effective postoperative pain control in children by using Visual Analogue Scale iVA.St It was a crospsemional study for two years. Sample sine was 90 with a mean age of 8.7 years. Patients were selected from the Department of Paediatric Surgery of Bangabandhu Sheikh Mujib Medical University (BSMMU). Dhaka; Bangladesh Institute of Child Health & Dhaka Shishu Hospital HliCH &DSH). Dhaka; and Dhaka Medical College hospital (DMC111. Dhaka. Children aged five to 12 years receiving postoperative analgesics were included in this study. All of them were mentally healthy. well responsive and cmoperative. Patients were selected in such a way that neither thee hod any malignant disease nor were they stoffernsg front any chronic pain or postoperative pain due to magical wound sepsis. Postoperative pain was measured by VAS from the first postoperative day to the seventh postoperative day and was graded by she Sriwatanakars method. It vans Plod that difference in pain scams were statistically nowsigo0ficant among the three institutes front the first postoperative day to the seventh postoperative day. Patients experienced moderate pain up to the third postoperative day, mild pain up to the fifth postoperative day and. ome pain up to the sowsh postoperative day. Postoperative pain was mu effectively controlled by currently used analgesics in paediatric surgery departments in these hospitals. So so find at the degree of effrctice postoperative pain control in children fierther study should be carried 0111 with large number of patients in different mares of Bangladesh.


Author(s):  
Daniel J. Lynch ◽  
James S. Lin ◽  
Kanu S. Goyal

Abstract Introduction This study looked to determine how providing written prescriptions of nonopioids affected postoperative pain medication usage and pain control. Materials and Methods Patients undergoing hand and upper-extremity surgery (n = 244) were recruited after the implementation of a postoperative pain control program encouraging nonopioids before opioids. Patients were grouped based on procedure type: bone (n = 66) or soft tissue (n = 178). Patients reported postoperative medication consumption and pain control scores. Two-tailed t-tests assuming unequal variance were performed to look for differences in postoperative pain control and medication consumption between those who were and were not given written prescriptions for nonopioids. Results For both soft tissue and bone procedure patients, a written prescription did not significantly affect patients’ postoperative pain control or medication consumption. Regardless of receiving a written prescription, patients who underwent soft tissue procedures consumed significantly more daily nonopioids than opioids. Conclusion Receiving written prescriptions for nonopioids may not have a significant effect on postoperative pain control or medication consumption. Patients undergoing soft tissue hand and upper extremity procedures may be more likely to consume more daily nonopioids than opioids postoperatively compared to bone procedure patients regardless of whether they receive a written prescription for nonopioids.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Atsushi Kotera

Abstract Background Postanesthetic shivering is an unpleasant adverse event in surgical patients. A nonsteroidal anti-inflammatory drug has been reported to be useful in preventing postanesthetic shivering in several previous studies. The aim of this study was to evaluate the efficacy of flurbiprofen axetil being a prodrug of a nonsteroidal anti-inflammatory drug for preventing postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries. Method This study is a retrospective observational study. I collected data from patients undergoing gynecologic laparotomy surgeries performed between October 1, 2019, and September 30, 2020, at Kumamoto City Hospital. All the patients were managed with general anesthesia with or without epidural analgesia. The administration of intravenous 50 mg flurbiprofen axetil for postoperative pain control at the end of the surgery was left to the individual anesthesiologist. The patients were divided into two groups: those who had received intravenous flurbiprofen axetil (flurbiprofen group) and those who had not received intravenous flurbiprofen axetil (non-flurbiprofen group), and I compared the frequency of postanesthetic shivering between the two groups. Additionally, the factors presumably associated with postanesthetic shivering were collected from the medical charts. Intergroup differences were assessed with the χ2 test with Yates’ correlation for continuity category variables. The Student’s t test was used to test for differences in continuous variables. Furthermore, a multivariate logistic regression analysis was performed to elucidate the relationship between the administration of flurbiprofen axetil and the incidence of PAS. Results I retrospectively examined the cases of 141 patients aged 49 ± 13 (range 21-84) years old. The overall postanesthetic shivering rate was 21.3% (30 of the 141 patients). The frequency of postanesthetic shivering in the flurbiprofen group (n = 31) was 6.5%, which was significantly lower than that in the non-flurbiprofen group (n = 110), 25.5% (p value = 0.022). A multivariate logistic regression analysis showed that administration of flurbiprofen axetil was independently associated with a reduced incidence of postanesthetic shivering (odds ratio 0.12; 95% confidence interval, 0.02-0.66, p value = 0.015). Conclusions My result suggests that intraoperative 50 mg flurbiprofen axetil administration for postoperative pain control is useful to prevent postanesthetic shivering in patients undergoing gynecologic laparotomy surgeries.


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