scholarly journals The Large-Scale Synthesis of Vinyl-Functionalized Silicon Quantum Dot and Its Application in Miniemulsion Polymerization

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Xuan-Dung Mai ◽  
Quang-Bac Hoang
Keyword(s):  
Large Scale ◽  
Miniemulsion Polymerization ◽  
Water Soluble ◽  
Molar Ratio ◽  
Biological Applications ◽  
Photoluminescence Properties ◽  
Polystyrene Nanoparticles ◽  
One Pot ◽  
Two Photon ◽  
Silicon Quantum Dot

Stable luminescence, size-tunability, and biocompatibility encourage the deployment of Cd-free NPs into diverse biological applications. Here we report one-pot synthesis of blue-emitting and polymerizable silicon quantum dots (Si QDs) from which water-soluble Si QDs embedded polystyrene nanoparticles (SiQD@PS NPs) were prepared using a miniemulsion polymerization approach. The hydrodynamic size of NPs was controlled by KOH to oleic acid molar ratio. Studies on the photoluminescence properties of SiQD@PS NPs in different conditions reveal that they exhibit two-photon luminescence property and high stability against pH and UV exposure. These NPs add new size regime to the Si QDs based luminescent makers for bioimaging and therapy applications.

scholarly journals Small water-soluble pyrimidine hexafluorophosphate derivatives with high two-photon absorption activities in the near-IR region and their biological applications

RSC Advances ◽  
2017 ◽  
Vol 7 (32) ◽  
pp. 20068-20075 ◽  
Author(s):  
Qiong Zhang ◽  
Rongting Guan ◽  
Xiaohe Tian ◽  
Lei Luo ◽  
Hongping Zhou ◽  
...  
Keyword(s):  
Cross Section ◽  
Living Cells ◽  
Water Soluble ◽  
Photon Absorption ◽  
Biological Applications ◽  
Two Photon Absorption ◽  
Small Water ◽  
Two Photon ◽  
Near Ir ◽  
Fluorescence Methods

Two imidazole–pyrimidine hexafluorophosphate derivatives (6P and 10P) are synthesized. The 2PA cross-section values (σ) were obtained by Z-scan and two-photon excited fluorescence methods. 6P and 10P can be used to quantify and image organelles in living cells and tissues.

Two-photon fluorescence imaging of mitochondria viscosity with water-soluble pyridinium inner salts

2022 ◽  
Author(s):  
Bin Fang ◽  
Beilin Zhang ◽  
Rongxiu Zhai ◽  
Limin Wang ◽  
Yang Ding ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Rational Design ◽  
Fluorescence Probe ◽  
Water Soluble ◽  
Biological Applications ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Rational design of mitochondrial viscosity probes with water-soluble two-photon (TP) fluorescence probe still remains a challenge in practical biological applications. Herein, three novel water-soluble TP active sulfosalt derivatives (Mito-Z, Mito-H,...

Preparation of PEG-rosin derivative for water soluble rosin flux

2016 ◽  
Vol 28 (4) ◽  
pp. 188-200 ◽  
Author(s):  
Kanlaya Phaphon ◽  
Sumrit Wacharasindhu ◽  
Amorn Petsom
Keyword(s):  
Large Scale ◽  
Gel Permeation Chromatography ◽  
Water Soluble ◽  
Molar Ratio ◽  
Scale Production ◽  
Solder Paste ◽  
Scanning Calorimetry ◽  
Corrosion Properties ◽  
Synthetic Process ◽  
Content Type

Purpose This study aims to synthesize polyethylene glycol (PEG)-rosin derivatives from rosin and PEG for the production of solid soldering fluxes. The PEG-rosin derivatives would be water soluble, and the resulting solid soldering fluxes would have reasonable wetting ability when combined with a low-halide-content activator. Design/methodology/approach This paper presents a synthetic process for PEG-rosin derivatives. The reaction conditions (including catalyst type, catalyst concentration, reaction temperature and PEG type) were optimized for the synthesis of PEG-rosin derivatives. The chemical and physical properties of PEG-rosin derivatives were characterized by Fourier transform infrared spectroscopy, carbon-13 nuclear magnetic resonance spectrometry, differential scanning calorimetry and gel permeation chromatography. The production and characteristics of water-soluble rosin fluxes (WSRFs) were studied according to the standards of the Japanese Industrial Standards (JIS) Committees. Findings WSRs were successfully synthesized from rosin and PEG using 2 per cent ZnO as a catalyst, with a 2:1 molar ratio of rosin:PEG at 250°C over 9 h. The resulting WSRs were completely soluble in water. As the PEG3000-rosin had the highest melting point (55.2°C), it was chosen for the preparation of the WSRFs. Activators such as succinic acid, glutaric acid, ethylamine hydrochloride and diethylamine hydrobromide were selected for use in the production of the fluxes. It was found that WSRF 09 and WSRF 04 gave the best performance with the lead-free Sn-0.7Cu solder alloy in terms of good solderability, low halide content (less than 1,500 ppm), high insulation resistance and low corrosion. These fluxes were applied to produce solder pastes with Sn-3.0Ag-0.5Cu alloy and they passed the performance tests as expected for solder paste. Research limitations/implications Further studies are necessary on large-scale production and to compare the performance of these fluxes to those from conventional water-soluble fluxes currently available in the market. Application of these fluxes on low-temperature solder alloys such as SnZn and SnBi (Ren et al., 2016) worth further study. Originality/value The classification of flux systems according to the JIS 3283 standard does not specify PEG-rosin derivatives in the flux; nevertheless, ranking of the flux systems based on the halide content and corrosion properties of activators would be useful information when selecting flux systems for electronics soldering in water-washable applications. The application of these fluxes in solder paste gave very promising results and is worth investigating into more detail, as well as field test.

One-Pot Synthesis of LiFePO4 Nano-Particles Dispersed in N-Containing Melamine-Formaldehyde Carbon Matrix as the Cathode Materials for Large Scale Lithium Ion Batteries

2018 ◽  
Vol 775 ◽  
pp. 342-349
Author(s):  
Supacharee Roddecha ◽  
Kantawich Jittmonkong ◽  
Malinee Sriariyana
Keyword(s):  
Ionic Conductivity ◽  
Surface Area ◽  
Large Scale ◽  
Carbon Matrix ◽  
Nano Particles ◽  
Pluronic F127 ◽  
Molar Ratio ◽  
Melamine Formaldehyde ◽  
One Pot ◽  
One Pot Synthesis

LiFePO4 is considered as the promising cathode material for a large-scale Li batteries used in electrical vehicles (EVs). However, a practical use of LiFePO4 cathode is limited by its low ionic conductivity, resulting in low battery’s power performance. This work, a facile and practical method to promote ionic conductivity and capacity of LiFePO4 was developed by dispersing LiFePO4 nanoparticles into a porous nitrogen-riched carbon matrix by employing one-pot synthesis approach. The N-containing carbon porous matrix was prepared by utilizing melamine-formaldehyde (MF) resin as the N-containing carbon precursor and Pluronic F127 as the porous template. The pseudo capacitive effect attributed from lone-pair electrons into melamine functional group was expected to support Li ion transport. After carbonization at 600 °C, uniform LiFePO4 nanocomposite clusters with an average size of about 50-300 nm were obtained. The influence of the molar ratio between pluronic F127 and melamine-formaldehyde (i.e. F127:MF molar ratio as 0:1, 0.03:1, 0.3:1) on the LiFePO4 nanocomposite’s morphology and crystalline structure was investigated by using scanning electron microscope and X-ray diffraction technique. The results show that increasing F127 concentrations support more porous structure formation, leading to a higher surface area but does not affect the LiFePO4 nanocrystalline structure. According to the highest surface area, the N-doped carbon coated LiFePO4 composite product obtained from the molar ratio of F127:MF as 0.3:1 exhibited highest discharging specific capacity of 158.1 mAh g-1, at a rate of 0.1 C and also shows high cycle stability.

scholarly journals Ultra-Small Fatty Acid-Stabilized Magnetite Nanocolloids Synthesized byIn SituHydrolytic Precipitation

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Kheireddine El-Boubbou ◽  
Rabih O. Al-Kaysi ◽  
Muhanna K. Al-Muhanna ◽  
Hassan M. Bahhari ◽  
Abdulaziz I. Al-Romaeh ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Targeted Delivery ◽  
Large Scale ◽  
Colloidal Stability ◽  
Elevated Temperatures ◽  
Metal Oxide Nanoparticles ◽  
Cost Effective ◽  
Water Soluble ◽  
Great Promise ◽  
One Pot

Simple, fast, large-scale, and cost-effective preparation of uniform controlled magnetic nanoparticles remains a major hurdle on the way towards magnetically targeted applications at realistic technical conditions. Herein, we present a unique one-pot approach that relies on simple basic hydrolyticin situcoprecipitation of inexpensive metal salts (Fe2+and Fe3+) compartmentalized by stabilizing fatty acids and aided by the presence of alkylamines. The synthesis was performed at relatively low temperatures (~80°C) without the use of high-boiling point solvents and elevated temperatures. This method allowed for the production of ultra-small, colloidal, and hydrophobically stabilized magnetite metal oxide nanoparticles readily dispersed in organic solvents. The results reveal that the obtained magnetite nanoparticles exhibit narrow size distributions, good monodispersities, high saturation magnetizations, and excellent colloidal stabilities. When the [fatty acid] : [Fe] ratio was varied, control over nanoparticle diameters within the range of 2–10 nm was achieved. The amount of fatty acid and alkylamine used during the reaction proved critical in governing morphology, dispersity, uniformity, and colloidal stability. Upon exchange with water-soluble polymers, the ultra-small sized particles become biologically relevant, with great promise for theranostic applications as imaging and magnetically targeted delivery vehicles.

Growth Mechanism and Characterization of Zinc Oxide Spheres

2012 ◽  
Vol 534 ◽  
pp. 169-172
Author(s):  
Shuang Xu
Keyword(s):  
Zinc Oxide ◽  
Hydrothermal Method ◽  
Growth Mechanism ◽  
Large Scale ◽  
Water Soluble ◽  
Experimental Results ◽  
Soluble Polymer ◽  
One Pot ◽  
Water Soluble Polymer

Novel uniform-sized, ZnO mesocrystal spheres have been synthesized on a large scale using a facile one-pot hydrothermal method in the presence of the water-soluble polymer poly. Sphere crystallinity was characterized by XRD and SEM. On the basis of the experimental results, we proposed a possible mechanism to elucidate the formation of ZnO spheres.

Solubility Enhancement of the Poorly Water-Soluble Antiulcer Drug Famotidine by Inclusion Complexation

2013 ◽  
Vol 6 (1) ◽  
pp. 1983-1989 ◽  
Author(s):  
Shabnam Ain ◽  
V Gupta ◽  
Babita K ◽  
Q Ain ◽  
J Dahiya
Keyword(s):  
Inclusion Complex ◽  
Dissolution Rate ◽  
Phosphate Buffer ◽  
Physical Mixture ◽  
Water Soluble ◽  
Molar Ratio ◽  
Phase Solubility ◽  
Distilled Water ◽  
Physicochemical Interaction ◽  
Mixture Phase

Aqueous solubility is a critical factor for optimum drug delivery. In the present study, we investigated the potential of drug-cyclodextrin complexation as an approach for improving the solubility and bioavailability of famotidine, an H2-receptor antagonist and acid reducing drug which has poor solubility and bioavailability. Solubility improvement of drug by β-cyclodextrin was done by simple complexation approach using physical, kneading and co-precipitation methods and compared with physical mixture. Phase solubility profile indicated that the solubility of famotidine was significantly increased in presence of β-cyclodextrin and shows a linear graph with β-cyclodextrin indicating formation of inclusion complexes in a 1:1 molar ratio. β-Cyclodextrin-famotidine mixture have maximum stability constant 1477.6 M-1. The inclusion complex ratio 1:1 of kneading mixture was selected based on drug release profile and compared with physical mixture. Further characterization was done by  using Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and scanning electron microscopy (SEM) to identify the physicochemical interaction between drug and carrier and its effect on dissolution. Dissolution rate studies for selected inclusion complex was performed in 0.1 N HCl (pH 1.2), phosphate buffer (pH 7.5) and distilled water (pH 6.8) and compared these to pure drug profile which was found to be 2.34 fold increase in distilled water, 1.83 fold in HCl and 2.01 fold in phosphate buffer (pH 7.5). These results suggest that the kneaded complex of famotidine with β-cyclodextrin as hydrophilic complexation agent can substantially enhance the solubility and dissolution rate. Such complex has promising potential to improve the bioavailability of famotidine.  

An Efficient and Improved Process for the Synthesis of Itopride Hydrochloride and Trimethobenzamide Hydrochloride

2018 ◽  
Vol 15 (4) ◽  
pp. 572-575 ◽  
Author(s):  
Ponnusamy Kannan ◽  
Samuel I.D. Presley ◽  
Pallikondaperumal Shanmugasundaram ◽  
Nagapillai Prakash ◽  
Deivanayagam Easwaramoorthy
Keyword(s):  
Large Scale ◽  
Hydroxylamine Hydrochloride ◽  
Scale Production ◽  
One Pot ◽  
Hydrochloride Salt ◽  
Environmental Friendly ◽  
Large Scale Production ◽  
Non Ulcer Dyspepsia ◽  
Itopride Hydrochloride ◽  
Yield And Purity

Aim and Objective: Itopride is a prokinetic agent used for treating conditions like non-ulcer dyspepsia. Itopride is administered as its hydrochloride salt. Trimethobenzamide is used for treating nausea and vomiting and administered as its hydrochloride salt. The aim is to develop a novel and environmental friendly method for large-scale production of itopride and trimethobenzamide. Materials and Methods: Itopride and trimethobenzamide can be prepared from a common intermediate 4- (dimethylaminoethoxy) benzyl amine. The intermediate is prepared from one pot synthesis using Phyrdroxybenzaldehye and zinc dust and further reaction of the intermediate with substituted methoxy benzoic acid along with boric acid and PEG gives itopride and trimethobenzamide. Results: The intermediate 4-(dimethylaminoethoxy) benzylamine is prepared by treating p-hydroxybenzaldehyde and 2-dimethylaminoethyl chloride. The aldehyde formed is treated with hydroxylamine hydrochloride. The intermediate is confirmed by NMR and the purity is analysed by HPLC. Conclusion: Both itopride and trimethobenzamide were successfully synthesized by this method. The developed method is environmental friendly, economical for large-scale production with good yield and purity.

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