scholarly journals Effect of High Intensity Interval and Continuous Swimming Training on Body Mass Adiposity Level and Serum Parameters in High-Fat Diet Fed Rats

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Guilherme L. da Rocha ◽  
Alex H. Crisp ◽  
Maria R. M. de Oliveira ◽  
Carlos A. da Silva ◽  
Jadson O. Silva ◽  
...  
Keyword(s):  
Body Mass ◽  
High Fat Diet ◽  
Interval Training ◽  
Mass Gain ◽  
The Body ◽  
Standard Diet ◽  
High Fat ◽  
Continuous Training ◽  
Body Mass Gain ◽  
Training Standard

This study aimed to investigate the effects of interval and continuous training on the body mass gain and adiposity levels of rats fed a high-fat diet. Forty-eight male Sprague-Dawley rats were randomly divided into two groups, standard diet and high-fat diet, and received their respective diets for a period of four weeks without exercise stimuli. After this period, the animals were randomly divided into six groups (n=8): control standard diet (CS), control high-fat diet (CH), continuous training standard diet (CTS), continuous training high-fat diet (CTH), interval training standard diet (ITS), and interval training high-fat diet (ITH). The interval and continuous training consisted of a swimming exercise performed over eight weeks. CH rats had greater body mass gain, sum of adipose tissues mass, and lower serum high density lipoprotein values than CS. The trained groups showed lower values of feed intake, caloric intake, body mass gain, and adiposity levels compared with the CH group. No significant differences were observed between the trained groups (CTS versus ITS and CTH versus ITH) on body mass gains and adiposity levels. In conclusion, both training methodologies were shown to be effective in controlling body mass gain and adiposity levels in high-fat diet fed rats.

scholarly journals Amomum villosum Lour. fruit extract ameliorates high-fat diet-induced body mass gain and adipogenic pathways in C57BL/6 mice

2021 ◽  
pp. 101473
Author(s):  
Ha-Rim Kim ◽  
Paulrayer Antonisamy ◽  
Ye-Seul Kim ◽  
Yong-Gwan Kwon ◽  
Do-Gon Ryu ◽  
...  
Keyword(s):  
Body Mass ◽  
High Fat Diet ◽  
Mass Gain ◽  
High Fat ◽  
Fruit Extract ◽  
Body Mass Gain ◽  
Amomum Villosum

Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet

2019 ◽  
Vol 66 ◽  
pp. 32-47 ◽  
Author(s):  
Laura E. Griffin ◽  
Dane W. Fausnacht ◽  
Jessica L. Tuzo ◽  
Adele K. Addington ◽  
Kathryn C. Racine ◽  
...  
Keyword(s):  
Body Mass ◽  
Interleukin 6 ◽  
High Fat Diet ◽  
Mass Gain ◽  
High Fat ◽  
Body Mass Gain

Acute effect of high-intensity interval training exercise on redox status in the ovaries of rats fed a high-fat diet

2021 ◽  
Vol 33 (12) ◽  
pp. 713
Author(s):  
Rodrigo L. Furtado ◽  
Jonathan Elias R. Martins ◽  
Maria Alice F. Oliveira ◽  
Denise D. Guerreiro ◽  
Naiza A. R. de Sá ◽  
...  
Keyword(s):  
High Intensity ◽  
High Fat Diet ◽  
Interval Training ◽  
Redox Status ◽  
Female Rats ◽  
Standard Diet ◽  
High Intensity Interval Training ◽  
High Fat ◽  
Antral Follicles ◽  
High Intensity Interval

This study demonstrates the effect of a single high-intensity interval training (HIIT) session on the redox status of rat ovaries with excess adiposity. Forty Wistar female rats (mean (±s.e.m.) weight 94.40 ± 13.40 g) were divided into two groups and fed either a standard diet (SD) or a high-fat diet (HFD) for 62 days. At the end of this period, the rats were subjected to a single HIIT session and were killed 24 h after exercise. Both groups subjected to exercise (SDex and HFDex) generated a significantly higher antioxidant environment by presenting a higher thiol content, which represents a lower oxidation rate of GSH than their respective controls (SD and HFD). The percentage of morphologically normal primary follicles decreased, whereas that of antral follicles increased, in the SDex group. In addition, the HFD group had a higher percentage of degenerated antral follicles than the SD and SDex groups. Cells immunoreactive for α-smooth muscle actin were seen in the cortical stroma and thecal layer enclosing late secondary and tertiary follicles in all groups. Moreover, heme oxygenase and cytochrome P450 family 19 subfamily A member 1 (Cyp19A1) labelling was seen in all antral follicles. Progesterone concentrations were significantly higher in the HFDex than SDex group. In conclusion, this study indicates that a single session of HIIT may result in an improvement in ovary redox status because of metabolic muscle activity by inducing physiological adaptation after exercise in a paracrine manner.

Hydration status of Greco-Roman wrestlers in an authentic precompetition situation

2013 ◽  
Vol 38 (6) ◽  
pp. 621-625 ◽  
Author(s):  
Vahur Ööpik ◽  
Saima Timpmann ◽  
Andres Burk ◽  
Innar Hannus
Keyword(s):  
Specific Gravity ◽  
Body Mass ◽  
Urine Osmolality ◽  
Mass Gain ◽  
The Body ◽  
Urine Specific Gravity ◽  
Hydration Status ◽  
Greco Roman ◽  
Reduced Body ◽  
Body Mass Gain

We assessed the urinary indexes of hydration status of Greco-Roman wrestlers in an authentic precompetition situation at the time of official weigh-in (OWI). A total of 51 of 89 wrestlers competing in the Estonian Championship in 2009 donated a urine sample. Questionnaire responses revealed that 27 wrestlers (body mass losers (BMLs)) reduced body mass before the competition, whereas 24 wrestlers (those who do not lose body mass (n-BMLs)) did not. In 42 wrestlers, values of urine specific gravity ≥1.020 and urine osmolality ≥700 mOsmol·kg−1 revealed a hypohydrated status. The prevalence of hypohydration in the BMLs (96%) was higher than in the n-BMLs (67%) (χ2 = 7.68; p < 0.05). The prevalence of serious hypohydration (urine specific gravity >1.030) was 5.3 times greater (χ2 = 8.32; p < 0.05) in the BMLs than in the n-BMLs. In the BMLs, the extent of body mass gain during the 16-h recovery (2.5 ± 1.2 kg) was associated (r = 0.764; p < 0.05) with self-reported precompetition body mass loss (4.3 ± 2.0 kg) and exceeded the body mass gain observed in the n-BMLs (0.7 ± 1.2 kg; p < 0.05). We conclude that hypohydration is prevalent among Greco-Roman wrestlers at the time of OWI. The prevalence of hypohydration and serious hypohydration is especially high among wrestlers who are accustomed to reducing body mass before competition. These results suggest that an effective rehydration strategy is needed for Olympic-style wrestlers, and that changes in wrestling rules should be considered to reduce the prevalence of harmful body mass management behaviours.

scholarly journals Suitability of a 10% fat diet for use in time-restricted feeding experiments with C57BL/6 mice

2020 ◽  
Vol 3 (3) ◽  
pp. 55
Author(s):  
Hiroyuki Sakakibara ◽  
Hiroki Matsuyama ◽  
Wataru Tanaka ◽  
Daigo Yokoyama ◽  
Shoji Matsumoto ◽  
...  
Keyword(s):  
Body Mass ◽  
Mass Gain ◽  
The Body ◽  
Free Access ◽  
Restricted Feeding ◽  
Feeding Experiments ◽  
Diet Induced Obesity ◽  
Body Mass Gain ◽  
Ad Libitum ◽  
Fat Diets

Background: There is growing interest in the possible role of circadian rhythms in feeding behavior and their effect on diet-induced obesity. However, it is unclear whether widely used purified diets are suitable for use as normal control diets for rodents undergoing time-restricted feeding studies. In the present study, we compared the effects of 4% and 10% fat diets on body mass gain and food consumption during time-restricted feeding (TRF).Methods: Ad libitum-fed male C57BL/6J mice had free access to AIN-93M (4% fat) or modified 10% fat diets, whereas TRF groups were only able to consume one of these diets twice daily, at ZT23:00–01:00 and ZT11:00–13:00, for 5 weeks.Results: Total energy consumptions by the TRF-4% and TRF-10% fat groups were 26.5% and 18.6%, respectively, less than that of the ad libitum-fed groups. The body mass gains by the 4% and 10% fat diet groups fed ad libitum were similar, but the gain by the TRF-4% fat group was markedly lower than that of the TRF-10% fat group. In addition, whereas the body mass gain by the TRF-10% fat group was similar to that of its ad libitum equivalent, the gain by the TRF-4% fat group was much lower than that of the equivalent ad libitum-fed group.Conclusion: We showed for the first time that a 10% fat diet (21.9% kcal from fat) is suitable for the maintenance of body mass gain during TRF of C57BL/6 mice.Keywords: ad libitum feeding, fat content, mouse, time-restricted feeding

scholarly journals Choline-deficient High-fat Diet-induced Steatohepatitis in BALB/c Mice

2021 ◽  
Vol 5 (2) ◽  
pp. 74
Author(s):  
Saut Horas Hatoguan Nababan ◽  
Seruni Tyas Khairunissa ◽  
Erni Erfan ◽  
Nafrialdi Nafrialdi ◽  
Ening Krisnuhoni ◽  
...  
Keyword(s):  
Fatty Acids ◽  
High Fat Diet ◽  
Transforming Growth Factor ◽  
Uncoupling Protein ◽  
Saturated Fatty Acids ◽  
The Body ◽  
Standard Diet ◽  
High Fat ◽  
Expression Levels ◽  
Relative Expression

Background: Non-alcoholic steatohepatitis (NASH) is an expanding cause of chronic liver disease worldwide, including Indonesia, with higher risk progression to cirrhosis and hepatocellular carcinoma. Preclinical experiments using several mice models have been conducted to clarify its complex pathogenesis. This study was designed to investigate whether BALB/c mice on a choline-deficient high-fat diet can be used as a model for NASH. Materials and Methods: BALB/c male mice were fed choline-deficient L-amino acid-defined high-fat diet (CDAHFD) or a standard diet for six weeks. The body and liver weights, liver histology, and plasma biochemistry were analyzed. The relative expression levels of tumor necrosis factor (TNF)α, transforming growth factor (TGF)β1, collagen-1α1 (COL1α1), glutathione peroxidase 1 (GPx1), and uncoupling protein 2 (UCP2) genes in the livers were analyzed using a two-step real time-polymerase chain reaction. Liver fatty acids composition was analyzed using gas chromatography with flame ionization detector (GC-FID). Results: CDAHFD induced steatohepatitis in BALB/c mice with increased plasma levels of alanine aminotransferase. The liver of CDAHFD-fed BALB/c mice showed upregulated relative expression levels of TNFα, TGFβ1, COL1α1, GPx1, and UCP2 genes. The liver fatty acid analysis showed a significant accumulation of saturated fatty acids (SFAs) and an increased ratio of n-6/n-3 polyunsaturated fatty acids (PUFAs) in the livers of CDAHFD-fed BALB/c mice. Conclusion: This study suggests that CDAHFD can induce steatohepatitis in BALB/c mice and therefore may be used as NASH mice model.Keywords: steatohepatitis, fatty liver, choline-deficient high fat diet, BALB/c 

scholarly journals Vpliv SNP znotraj FTO in LEP gena na prirast telesne mase pri govedu

2016 ◽  
Vol 108 (1) ◽  
pp. 17
Author(s):  
Iva ČERNOŠA ◽  
Žan PIRC ◽  
Andrej RENČELJ
Keyword(s):  
Body Mass ◽  
Growth Traits ◽  
Mass Gain ◽  
The Body ◽  
Polymorphic Site ◽  
Fto Gene ◽  
Body Mass Gain ◽  
Time Period ◽  
Holstein Friesian ◽  
Lep Gene

Body mass gain in a certain time period is one of the most important parameters in beef production. Some candidate genes, which have major impact on growth traits, are known from the literature, notably among them the FTO (fat mass and obesity-associated) and LEP (leptin) locus. In our experiment, we assessed the frequency of alleles at two polymorphic sites within the FTO gene (FTO6 and FTO10) and at polymorphic site in the LEP gene in a sample of Aberdeen Angus (AA) and Holstein Friesian (HF) breeds. In a larger sample, containing dairy and beef cattle breeds we tested the association of these three SNPs with the body mass gain in a 200-day period (between 165th and 365th day of age). In our material we could not confirm the linkage between two SNPs within the FTO locus, due to the existence of the region with high recombination rate between exon 5 and intron 5 in the FTO gene. We demonstrated significant impact of birth weight, breed and SNPs in the FTO gene on the growth. The effect of the polymorphic site within the LEP gene could not be confirmed.

scholarly journals The TOTUM-63 Supplement and High-Intensity Interval Training Combination Limits Weight Gain, Improves Glycemic Control, and Influences the Composition of Gut Mucosa-Associated Bacteria in Rats on a High Fat Diet

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1569
Author(s):  
Marine Dupuit ◽  
Vivien Chavanelle ◽  
Benoit Chassaing ◽  
Fanny Perriere ◽  
Monique Etienne ◽  
...  
Keyword(s):  
Glycemic Control ◽  
High Intensity ◽  
High Fat Diet ◽  
Interval Training ◽  
Standard Diet ◽  
High Intensity Interval Training ◽  
High Fat ◽  
Beneficial Effects ◽  
Α Diversity ◽  
High Intensity Interval

Obesity and prediabetes are the two strongest risk factors of type 2 diabetes. It has been reported that TOTUM-63, a polyphenol-rich plant extract, has beneficial effects on body weight (BW) and insulin resistance in mice fed a high fat diet (HFD). The study aim was to determine whether high-intensity interval training (HIIT) and/or TOTUM-63 supplementation improved body composition and glycemic control and gut microbiota composition in a Western diet-induced obesity rat model. Wistar rats received a standard diet (CTRL; control; n = 12) or HFD (HFD; n = 48) for 16 weeks. Then, HFD rats were divided in four groups: HFD, HFD + TOTUM-63 (T63), HFD + HIIT (HIIT), and HFD + HIIT +T63 (HIIT + T63). Training was performed 4 days/week for 12 weeks. TOTUM-63 was included in diet composition (2%). The HIIT + T63 combination significantly limited BW gain, without any energy intake modulation, and improved glycemic control. BW variation was correlated with increased α-diversity of the colon mucosa microbiota in the HIIT + T63 group. Moreover, the relative abundance of Anaeroplasma, Christensenellaceae and Oscillospira was higher in the HIIT + T63 group. Altogether, these results suggest that the HIIT and TOTUM-63 combination could be proposed for the management of obesity and prediabetes.

scholarly journals High-intensity interval training ameliorates high-fat diet-induced elevation of aminotransferases in male Wistar rats

2021 ◽  
Vol 23 (3) ◽  
pp. 111-115
Author(s):  
Qazaleh Asqari ◽  
Farhad Gholami ◽  
Jabbar Bashiri ◽  
Adel Donyaei
Keyword(s):  
High Fat Diet ◽  
Wistar Rats ◽  
Interval Training ◽  
Serum Levels ◽  
Diet Group ◽  
Standard Diet ◽  
High Intensity Interval Training ◽  
High Fat ◽  
Male Wistar Rats ◽  
High Intensity Interval

Background and aims: A high-fat diet increases triglyceride (TG) accumulations in hepatocytes and results in non-alcoholic fatty liver diseases (NAFLDs). In this regard, this study investigated the effect of high-intensity interval training (HIIT), along with a high-fat diet on the serum levels of aminotransferases in male Wistar rats. Methods: Forty male Wistar rats were randomly assigned to the standard diet, high-fat diet, exercise + standard diet, and exercise + high-fat diet groups (each containing 10 animals). HIIT program consisted of 6-12 repetitions of 2-minute highs-intensity exercise (85-90% of the maximum speed) interspersed with 1-minute low-intensity exercise (45-50% peak speed) with the frequency of 5 sessions a week over 12 weeks. High-fat diet groups received a diet regimen including 58% fat, 25% protein, and 17% carbohydrate, ad libitum. The blood samples were taken from the left ventricle 48 hours following the last intervention to assess TG, alanine aminotransferase (ALT), and aspartate amino-transferase (AST) concentrations. Data were analyzed using one-way ANOVA and Tukey’s post-hoc tests. Results: The findings showed the mean of ALT, AST, and TG in the high-fat diet group was significantly greater compared to the standard diet group (P=0.001). Furthermore, the mean of ALT, AST, and TG in the exercise + high-fat diet group was significantly lower in comparison with the high-fat diet group (P=0.01, P=0.017, and P=0.012, respectively). Conclusion: Although HIIT ameliorated high-fat diet-induced elevations in the serum levels of TG, ALT, and AST, they did not reach the baseline levels. Thus, it may indicate that a diet as the underlying cause of NAFLDs is more important than any other interventions such as exercise.

scholarly journals Effect of High Fat Diet on Body Weight, Visceral Fat Weight, and PPARG Expressions on Visceral Fat in Mice

2021 ◽  
Vol 57 (3) ◽  
pp. 186
Author(s):  
Cantika Putri Melyana ◽  
Sony Wibisono Mudjanarko ◽  
Lilik Herawati ◽  
Mohammad Anam Al-Arif ◽  
Purwo Sri Rejeki
Keyword(s):  
Body Weight ◽  
Visceral Fat ◽  
High Fat Diet ◽  
Alternative Therapy ◽  
The Body ◽  
Control Group ◽  
Standard Diet ◽  
High Fat ◽  
Control Group Design ◽  
Global Epidemic

Obesity becomes a global epidemic nowadays. The high-fat diet is used as an alternative therapy for obesity. The optimal composition of a high-fat diet to reduce body weight is still unknown. This study aimed to determine which components of a high-fat diet can decrease body weight, visceral fat, and PPARG expression of visceral fat. This study was conducted at the Faculty of Veterinary Medicine, Universitas Airlangga, for three months by using a randomized post-test only control group design. Fifty male mice, 2-3 months old, 18-30 grams were adapted for one week given standard diet AIN93-M, then mice were divided into five groups, namely K1 (control group, 12% fat, 20% protein, 62% carbs); K2 (30% fat, 60% proteins, 0% carbs); K3 (45% fat, 45% protein, 0% carbs);  K4 (60% fat, 30% protein, 0% carbs); and K5 (75% fat, 15% protein, 0% carbs). Bodyweight was measured before and after treatment, then the visceral fat and PPARG expressions were evaluated. Statistical comparisons were performed using Statistical Package for the Social Sciences (SPSS) software. After treatment, there were forty-three mice. The body weight and visceral fat weight of the mice with a high-fat diet were decreased. The most significant changes in body weight were in K4 with -9,60 ± 3,806 grams reduction. The bodyweight of mice in K5, slightly increased than K2-K4. This could be caused by the hormesis phenomenon. PPARG expressions decreased in groups with a high-fat diet but increased in K5. The composition of a high-fat diet in group K4 was the most optimal to decrease the body weight, visceral fat, and PPARG expressions in mice

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