scholarly journals Laryngeal Langerhans Cell Histiocytosis Presenting with Neck Mass in an Adult Woman

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Hesam Jahandideh ◽  
Yasser Nasoori ◽  
Sara Rostami ◽  
Mahdi Safdarian
Keyword(s):  
Head And Neck ◽  
Langerhans Cell Histiocytosis ◽  
Pediatric Patients ◽  
Neck Region ◽  
Rare Condition ◽  
Neck Mass ◽  
Langerhans Cell ◽  
Adult Woman ◽  
Head And Neck Region ◽  
Laryngeal Involvement

Langerhans cell histiocytosis (LCH) is a very rare condition that commonly affects the head and neck region. There are very few cases of isolated laryngeal involvement by LCH, mostly reported in pediatric patients. Here, we report a case of laryngeal LCH in a 62-year-old woman presenting with a neck mass several weeks ago. The clinical and histopathological findings are reported with a brief discussion about the disease.

Head and Neck Langerhans Cell Histiocytosis

1997 ◽  
Vol 106 (6) ◽  
pp. 526-532 ◽  
Author(s):  
Kenneth O. Devaney ◽  
Alfio Ferlito ◽  
Mathew J. Putzi ◽  
Alessandra Rtnaldo
Keyword(s):  
Head And Neck ◽  
Langerhans Cell Histiocytosis ◽  
Neck Region ◽  
Langerhans Cell ◽  
Skeletal System ◽  
Head And Neck Region ◽  
The Past ◽  
System Disease ◽  
Secondary Infections ◽  
Multifocal Disease

Among the potential sites of involvement by Langerhans cell histiocytosis (LCH), the head and neck region is the most commonly cited. Though principally a pediatric disease, LCH can affect any age group. It can be unifocal (skeletal) or multifocal (skeletal and/or visceral); it appears as though the presence of visceral lesions is more common in the youngest patients, and may be associated in some with a rapidly progressive course resulting in death. Head and neck manifestations may mimic such varied entities as eczema, otitis media, osteomyelitis, and cholesteatoma. Current approaches to therapy are less aggressive than they were in the past, and are particularly intended to monitor for and treat any complicating secondary infections (which may develop in the youngest patients with multifocal disease including visceral involvement). The prognosis is very good for unifocal skeletal system disease, and poor for multifocal disease with involvement of tissues other than bone.

Outcomes After Proton Therapy for Pediatric Patients With Cancers of the Head and Neck Region

2013 ◽  
Vol 87 (2) ◽  
pp. S597
Author(s):  
C.E. Hill-Kayser ◽  
R. Bagatell ◽  
A. Reilly ◽  
R. Womer ◽  
N. Balamuth ◽  
...  
Keyword(s):  
Head And Neck ◽  
Proton Therapy ◽  
Pediatric Patients ◽  
Neck Region ◽  
Head And Neck Region

Intramuscular Hemangioma of the sternocleidomastoid muscle: A Rare Unusual Neck Mass

2020 ◽  
Vol 13 (1) ◽  
pp. 78-82
Author(s):  
Brihaspati Sigdel ◽  
Rajesh Maharjhan ◽  
Tulika Dubey ◽  
Bhima Neupane
Keyword(s):  
Head And Neck ◽  
Rare Case ◽  
Neck Region ◽  
Neck Mass ◽  
Sternocleidomastoid Muscle ◽  
Benign Tumors ◽  
Head And Neck Region ◽  
Intramuscular Hemangioma ◽  
Slow Growing ◽  
Extensive Involvement

Hemangiomas of the head and neck region comprise about 60 to 70% of all benign tumors. Intramuscular hemangioma is a rare, slow-growing, angiomatous tumor. We report a rare case of an Intramuscular Hemangioma of Right sternocleidomastoid muscle in a six years old girl presenting for four years and with extensive involvement necessitating excision. Microscopic excision reduces the risk of recurrence.

High Prevalence of BRAF V600E Mutations in Langerhans Cell Histiocytosis of Head and Neck in Chinese Patients

2019 ◽  
Vol 27 (8) ◽  
pp. 836-843
Author(s):  
Xiaoxiao Liu ◽  
Ye Zhang ◽  
Chuan-Xiang Zhou
Keyword(s):  
Head And Neck ◽  
Langerhans Cells ◽  
Langerhans Cell Histiocytosis ◽  
Neck Region ◽  
Braf V600e Mutation ◽  
Langerhans Cell ◽  
Braf V600e ◽  
Chinese Patients ◽  
Clonal Proliferation ◽  
High Prevalence

Langerhans cell histiocytosis (LCH) is characterized by clonal proliferation of Langerhans cells and has been classified as a hematolymphoid tumor. BRAF V600E mutation was found to be frequent in LCH; however, it has also been reported that Asia patients with LCH tend to show a lower rate of BRAF V600E mutation. In this study, we found LCH from the head and neck region often involved bone especially the posterior of the mandible and presented a high prevalence of BRAF V600E mutation in Chinese patients. Our findings also showed immunohistochemical detection correlated very well to DNA sequencing of BRAF alterations, which may be useful in the diagnosis of LCH, especially in cases with a low proportion of Langerhans cells, and BRAF inhibitors might be a treatment option for patients with LCH harboring BRAF V600E mutation.

Kimura's disease

1996 ◽  
Vol 110 (11) ◽  
pp. 1084-1087 ◽  
Author(s):  
Nalinikanth Pamaraju ◽  
S. A. Khalifa ◽  
Abdulla Darwish ◽  
K. O. Paulose ◽  
Nissar Ahmed ◽  
...  
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Neck Region ◽  
Rare Condition ◽  
Malignant Tumour ◽  
Kimura’S Disease ◽  
Unknown Aetiology ◽  
Head And Neck Region ◽  
Arab Patient

AbstractKimura's disease is a rare condition of unknown aetiology. It usually presents as a mass in the head and neck region. The diagnosis is confirmed by biopsy and usually treated by excision even though recurrence is common. This condition can be mistaken for a malignant tumour. In this case report Kimura's disease presented as a nonspecific lymphadenitis in an Arab patient.

Mandibular condyle erosion and sclerosis in pediatric patients treated with radiotherapy to the head and neck region

2014 ◽  
Vol 61 (8) ◽  
pp. 1479-1480 ◽  
Author(s):  
Catherine E. Mercado ◽  
Stephen B. Little ◽  
Claire Mazewski ◽  
Frederick P. Schwaibold ◽  
Natia Esiashvili
Keyword(s):  
Head And Neck ◽  
Pediatric Patients ◽  
Mandibular Condyle ◽  
Neck Region ◽  
Head And Neck Region

scholarly journals Clinical and Dermoscopic Features of Melanocytic Lesions on the Face Versus the External Ear

2021 ◽  
pp. e2021124
Author(s):  
Teresa Deinlein ◽  
Andreas Blum ◽  
Günter Schulter ◽  
Holger A. Haenssle ◽  
Ralph Braun ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Head And Neck ◽  
Neck Region ◽  
Rare Condition ◽  
Image Database ◽  
External Ear ◽  
Head And Neck Region ◽  
Melanocytic Lesions ◽  
The Face

Introduction: Melanoma of the external ear is a rare condition accounting for 7-20% of all melanomas of the head and neck region. They present classical features of extra-facial melanomas clinically and dermoscopically. In contrast, facial melanomas show peculiar patterns in dermoscopy. Objectives:  We evaluate whether there are clinical and/or dermoscopic differences in melanocytic lesions located either at the external ear or on the face. Methods: In this retrospective study we reviewed an image database for clinical and dermoscopic images of melanomas and nevi located either on the face or at the level of the external ear. Results: 65 patients (37 men; 63.8%) with 65 lesions were included. We found no significant differences in comparing face melanomas with melanomas at the level of the external ear, neither clinically nor dermoscopically. However, we provided evidence for differences in some clinical and dermoscopic features of melanomas and nevi of the external ear. Conclusions: In this study, we reported no significant differences in comparing melanomas on the face with melanomas of the external ear, both clinically and dermoscopically. Furthermore, we provided data on clinical and dermoscopic differences comparing nevi and melanoma of the external ear.

scholarly journals Aneurysmal bone cyst in the head and neck region of the pediatric patients: a review

2021 ◽  
Vol 8 (11) ◽  
pp. 1914
Author(s):  
Santosh Kumar Swain
Keyword(s):  
Head And Neck ◽  
Pediatric Patients ◽  
Case Reports ◽  
Case Series ◽  
Neck Region ◽  
Surrounding Tissue ◽  
Original Research ◽  
Head And Neck Region ◽  
Complete Surgical Excision ◽  
Neck Area

Aneurysmal bone cysts (ABCs) are benign, vascular and cystic bony tumors which can be rapidly expanding and locally cause destruction of the surrounding tissue. ABCs in the head and neck area are usually found in patients with younger age group. ABC in the head and neck region of children may vary in presentations and severity.  ABCs are commonly found in mandible, sinonasal tract and cranium in head and neck region. Imaging and histopathological examinations confirm the diagnosis. Complete surgical excision is the treatment of choice. ABC which is secondary to underlying bone pathology like osteoblastoma may refractory to treatment. ABC in the head and neck region are uncommon and should be considered as differential diagnosis of bony and vascular lesions in the locations like mandible, sinonasal area, cranium, mastoid bone and spine. The review article includes case series, case reports and original research on ABCs manifesting in the head and neck area published in the English language. All literatures identified via Scopus, Google scholar, Medline and PubMed were analyzed individually. Articles of ABCs included according to specified eligibility criteria. The total number of articles were 78 (41 case reports; 37 cases series; 8 original articles). ABCs rapidly grow with expansile manner and result in destruction of bone and surrounding tissue in the head and neck region, so clinicians must think about this clinical entity to diagnose correctly and treat appropriately. The aim of the article is providing a comprehensive review of the ABC in the head and neck region of the pediatric patients.

scholarly journals An Unusual Presentation of a Neck Dermoid Cyst

2014 ◽  
Vol 5 (4) ◽  
pp. 237-239
Author(s):  
Geetika Arora ◽  
Sumit Bhateja
Keyword(s):  
Head And Neck ◽  
Dermoid Cyst ◽  
Rare Case ◽  
Squamous Epithelium ◽  
Neck Region ◽  
Neck Mass ◽  
Unusual Presentation ◽  
Benign Lesions ◽  
Head And Neck Region ◽  
Lateral Region

ABSTRACT Dermoid cysts are cystic malformations lined with squamous epithelium and constitute 1.6 to 6.9% of all cysts in the head and neck area. Within head and neck region, they are predominantly found in orbital, oral and nasal regions (over 80%) and remainder found in occipital, frontal, lip, neck, soft palate. Dermoid cysts are benign lesions usually presenting as a mid line neck mass. They rarely appear in lateral region. So, the purpose of this report is to present and discuss a rare case of posterolateral cervical dermoid cyst. How to cite this article Bhateja S, Arora G. An Unusual Presentation of a Neck Dermoid Cyst. World J Dent 2014; 5(4):237-239.

scholarly journals Primary Oro-Facial Manifestations of Langerhans Cell Histiocytosis in Pediatric Age: A Bi-Institutional Retrospective Study on 45 Cases

Children ◽  
2020 ◽  
Vol 7 (9) ◽  
pp. 104
Author(s):  
Saverio Capodiferro ◽  
Angela Tempesta ◽  
Luisa Limongelli ◽  
Giuseppe Ingravallo ◽  
Eugenio Maiorano ◽  
...  
Keyword(s):  
Bone Loss ◽  
Head And Neck ◽  
Langerhans Cell Histiocytosis ◽  
Alveolar Bone ◽  
Early Stage ◽  
Neck Region ◽  
Pediatric Dentistry ◽  
Langerhans Cell ◽  
Clinical Appearance ◽  
Periodontal Tissues

Aims: Langerhans Cell Histiocytosis is a rare hematologic disorder usually affecting children and most commonly involving the head and neck region. Primary oro-facial manifestations are rare, and their diagnosis is often challenging as they are numerous and often resemble common pathologies, refractory to conventional medical and/or instrumental treatments. For such reasons, the diagnosis is frequently delayed, as is the following staging and therapy onset. We retrospectively studied 45 pediatric patients affected by Langerhans Cell Histiocytosis with onset in the head and neck, to examine their clinical and radiological features at the early stage. Materials and Methods: The study was a retrospective bi-institutional analysis (Department of Pediatric Dentistry and Pediatric Oncology of “Sapienza” University of Rome, Department of Interdisciplinary Medicine of the University of Bari “Aldo Moro”), which enrolled 45 patients (age range 0–18 year-old) affected by Langerhans Cell Histiocytosis with oro-facial onset. Data regarding clinical appearance, number, site, synchronous or metachronous occurrence, involved tissues/organs, radiographic features and clinical outcomes were collected, listed and overall differentiated by two age ranges (0–10-year-olds and 10–18-year-olds). Results: Patients were 26 males and 19 females, with an average age at the time of diagnosis of 4.8 ± 3.8 years (median = 3.9 years). The most common findings were inflamed, hyperplastic, painful and often ulcerated gingival lesions (22 cases), associated with deciduous tooth mobility and/or dislocation with bone loss in 18 cases, followed by nine single eosinophilic granulomas of the mandible and two of the maxilla. Lesions of the palatal mucosa were observed in six patients; nine patients showed on radiograms the characteristic “floating teeth” appearance in the mandible with synchronous lesions of the maxilla in six. Paresthesia was relatively un-frequent (three cases) and the pathological fracture of the mandible occurred in six. Head/neck lymph nodes involvement was associated with oral lesions in 12 cases and skull lesions in 14. Otitis (media or externa) was detected in four instances, exophthalmia in two, cutaneous rush in nine, contextual presence or subsequent onset of insipidus diabetes in eight. As for therapy, single or multiple small jaw lesions were all surgically removed; chemotherapy with vinblastine alone or associated with corticosteroids was the principal treatment in almost the 80% of cases; more than 50% of patients received corticosteroids, while only three patients received adjunctive radiotherapy. The overall mortality account for less than 9% (four of 45 cases) and recurrence observed in eight patients after therapy. Conclusions: Langerhans Cell Histiocytosis may mimic several oro-facial inflammatory and neoplastic diseases. Considering the potential disabling sequela following head and neck localization of Langerhans Cell Histiocytosis in children, especially at the periodontal tissues with teeth and alveolar bone loss, lesion recognition along with the histological examination of suspicious tissues is mandatory to achieve an early diagnosis and to prevent further organ involvement.

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