scholarly journals Breast Cancer Metastasis to the Stomach That Was Diagnosed after Endoscopic Submucosal Dissection

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Masahide Kita ◽  
Masashi Furukawa ◽  
Masaya Iwamuro ◽  
Keisuke Hori ◽  
Yoshiro Kawahara ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Endoscopic Submucosal Dissection ◽  
Cancer Metastasis ◽  
Radical Mastectomy ◽  
Breast Cancer Metastasis ◽  
Signet Ring Cell ◽  
Axillary Lymph ◽  
Submucosal Dissection ◽  
Greater Curvature ◽  
Cystic Disease Fluid Protein

A 52-year-old woman presented with stage IIB primary breast cancer (cT2N1M0), which was treated using neoadjuvant chemotherapy (epirubicin, cyclophosphamide, and paclitaxel). However, the tumor persisted in patchy areas; therefore, we performed modified radical mastectomy and axillary lymph node dissection. Routine endoscopy at 8 months revealed a depressed lesion on the gastric angle’s greater curvature, and histology revealed signet ring cell proliferation. We performed endoscopic submucosal dissection for gastric cancer, although immunohistochemistry revealed that the tumor was positive for estrogen receptor, mammaglobin, and gross cystic disease fluid protein-15 (E-cadherin-negative). Therefore, we revised the diagnosis to gastric metastasis from the breast cancer.

scholarly journals A Case of 10-Year Survival after Adrenalectomy for Isolated Adrenal Metastasis of Breast Cancer

Reports ◽  
2020 ◽  
Vol 3 (3) ◽  
pp. 22
Author(s):  
Tsuyoshi Nakagawa ◽  
Goshi Oda ◽  
Akihiro Yano ◽  
Hiroshi Kawachi ◽  
Hiroyuki Uetake
Keyword(s):  
Breast Cancer ◽  
Hormone Therapy ◽  
Cancer Metastasis ◽  
Ductal Carcinoma ◽  
Radical Mastectomy ◽  
Breast Cancer Metastasis ◽  
Adrenal Metastasis ◽  
Pathological Examination ◽  
Endoscopic Adrenalectomy ◽  
Axillary Lymphadenectomy

Isolated adrenal metastasis of breast cancer is very rare, so adrenalectomy for breast cancer metastasis is rarely performed. The case of a breast cancer patient with five-year survival after resection of a left isolated adrenal metastasis is presented. A 70-year-old woman underwent left modified radical mastectomy and axillary lymphadenectomy for invasive ductal carcinoma (T2N1M0) 9 years earlier. At regular follow-up, a left adrenal mass, 4 cm in diameter, was seen on ultrasound examination and computed tomography (CT). Endoscopic adrenalectomy was performed. Pathological examination confirmed isolated adrenal metastasis of breast cancer. After surgery, hormone therapy was given for 5 years. Ten years after adrenalectomy, no metastatic lesions in other organs have been found on CT. Adrenalectomy for a metastatic adrenal tumor of breast cancer may provide survival benefits when combined with systemic hormone therapy and chemotherapy, particularly in patients with disease confined to the adrenal glands.

scholarly journals Detection of Circulating Tumor Cells in Early-Stage Breast Cancer Metastasis to Axillary Lymph Nodes

2007 ◽  
Vol 13 (14) ◽  
pp. 4105-4110 ◽  
Author(s):  
Taku Nakagawa ◽  
Steve R. Martinez ◽  
Yasufumi Goto ◽  
Kazuo Koyanagi ◽  
Minoru Kitago ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Cancer Metastasis ◽  
Early Stage ◽  
Breast Cancer Metastasis ◽  
Early Stage Breast Cancer ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph

scholarly journals Anal metastasis as the sentinel and isolated presentation of invasive ductal breast carcinoma

2016 ◽  
Vol 98 (5) ◽  
pp. e68-e70 ◽  
Author(s):  
C Rengifo ◽  
S Titi ◽  
J Walls
Keyword(s):  
Breast Cancer ◽  
Breast Carcinoma ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Invasive Ductal Breast Carcinoma ◽  
Ductal Breast Carcinoma ◽  
The Uk ◽  
Expanding Population

Breast cancer currently affects 1 in 8 women in the UK during their lifetime. Common sites for breast cancer metastasis include the axillary lymph nodes, bones, lung, liver, brain, soft tissue and adrenal glands. There is well documented evidence detailing breast metastasis to the gastrointestinal tract but anal metastasis is exceptionally rare. We present the case of a 78-year-old woman with an anal metastasis as the sentinel and isolated presentation of an invasive ductal breast carcinoma. As advances in the treatment of breast cancer improve, and with an ageing and expanding population, there will be an increasing number of cancer survivors, and more of these unusual presentations may be encountered in the future.

scholarly journals A Case of Suspected Breast Cancer Metastasis to Brachial Plexus Detected by Magnetic Resonance Neurography

2016 ◽  
Vol 9 (2) ◽  
pp. 395-399 ◽  
Author(s):  
Atsushi Mizuma ◽  
Chikage Kijima ◽  
Eiichiro Nagata ◽  
Shunya Takizawa
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance ◽  
Brachial Plexus ◽  
Cancer Metastasis ◽  
Breast Cancer Metastasis ◽  
Brachial Plexopathy ◽  
Axillary Lymph ◽  
Gallium Scintigraphy ◽  
Mr Neurography ◽  
Motor Weakness

Metastasis of breast cancer is often detected through a long-term course and difficult to diagnose. We report a case of brachial plexopathy suspected to be the initial lesion of breast cancer metastasis, which was only detected by magnetic resonance (MR) neurography. A 61-year-old woman was admitted to our hospital within 2 years after operation for breast cancer because of progressive dysesthesia and motor weakness initially in the upper limb on the affected side and subsequently on the contralateral side. Enhanced computed tomography, axillary lymph node echo, gallium scintigraphy, and short tau inversion recovery MR images showed no abnormalities. MR neurography revealed a swollen region in the left brachial plexus. We suspected neuralgic amyotrophy and initiated treatment with intravenous immunoglobulin therapy and steroid therapy. However, there was no improvement, and the progression of motor weakness in the bilateral lower limbs appeared over 4 years. Concomitant elevation of carbohydrate antigen 15-3 level (58.9 U/ml) led us to suspect breast cancer metastasis, which was associated with the worsening of neurological findings, although gallium scintigraphy and bone scintigraphy showed no inflammatory and metastatic lesions. Swelling of the cauda equina in enhanced lumbar MR imaging and abnormal accumulation at the brachial plexus and cervical spinal cord in positron-emission tomography were newly detected contrary to the normal findings on the gallium scintigraphy, which suggested cerebrospinal fluid seeding. We suspected breast cancer metastasis about the initial brachial plexopathy based on the clinical course. MR neurography may be a helpful tool to detect metastatic lesion, especially in nerve roots.

scholarly journals CXCR4 and Axillary Lymph Nodes: Review of a Potential Biomarker for Breast Cancer Metastasis

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
David Hiller ◽  
Quyen D. Chu
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Cancer Metastasis ◽  
Breast Cancer Diagnosis ◽  
Breast Cancer Metastasis ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Peripheral Lymph ◽  
Potential Biomarker ◽  
Node Metastases

CXCR4 is a 7-transmembrane G-protein chemokine receptor that allows for migration of hematopoietic cells from the bone marrow to the peripheral lymph nodes. Research has shown CXCR4 to be implicated in the invasion and metastasis of several cancers, including carcinoma of the breast. CXCL12 is the ligand for CXCR4 and is highly expressed in areas common for breast cancer metastasis, including the axillary lymph nodes. Axillary lymph nodes positive for breast carcinoma have been an important component of breast cancer diagnosis, treatment, and subsequent research. The goal of this paper is to analyze the literature that has explained the pathways from CXCR4 expression to breast cancer metastasis of the lymph nodes and the prognostic and/or predictive implications of lymph node metastases in the presence of elevated CXCR4.

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