scholarly journals Recurrent Pericarditis, an Unexpected Effect of Adjuvant Interferon Chemotherapy for Malignant Melanoma

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Farhan Ashraf ◽  
Fady Marmoush ◽  
Muhammad Ismail Shafi ◽  
Ashish Shah
Keyword(s):  
Adjuvant Chemotherapy ◽  
Malignant Melanoma ◽  
Interferon Therapy ◽  
Young Female ◽  
Good Effect ◽  
Recurrent Pericarditis ◽  
Drug Induced ◽  
Cardiac Pathology ◽  
Adjuvant Interferon

Drug-induced pericarditis is a well-described cardiac pathology that can result from a variety of medications; however, interferon-mediated pericarditis is extremely rare. We present a case of a young female with recurrent pericarditis due to interferon therapy. The role of interferon in adjuvant chemotherapy is well known and yields good effect, but this case highlights the very uncommon phenomena of interferon induced pericarditis and the significant distress it can cause.

scholarly journals Erratum to: The role of BRAF mutation in patients with high-risk malignant melanoma treated with high-dose adjuvant interferon therapy

2015 ◽  
Vol 32 (3) ◽  
Author(s):  
Tulay Akman ◽  
Ilhan Oztop ◽  
Yasemin Baskin ◽  
Mahdi Akbarpour ◽  
Olcun Umit Unal ◽  
...  
Keyword(s):  
High Risk ◽  
Malignant Melanoma ◽  
Braf Mutation ◽  
Interferon Therapy ◽  
High Dose ◽  
Adjuvant Interferon

The role of BRAF mutation in patients with high-risk malignant melanoma treated with high-dose adjuvant interferon therapy

2014 ◽  
Vol 32 (1) ◽  
Author(s):  
Tulay Akman ◽  
Ilhan Oztop ◽  
Yasemin Baskin ◽  
Mahdi Akbarpour ◽  
Olcun Umit Unal ◽  
...  
Keyword(s):  
High Risk ◽  
Malignant Melanoma ◽  
Braf Mutation ◽  
Interferon Therapy ◽  
High Dose ◽  
Adjuvant Interferon

P-18 Autoimmune disease during adjuvant interferon therapy in patients with malignant melanoma

2004 ◽  
Vol 14 (4) ◽  
pp. A22
Author(s):  
M. Karaoli ◽  
T. Petrakopoulou ◽  
N. Pergantas ◽  
P. Balgouranoudi ◽  
A. Yiacoumettis
Keyword(s):  
Malignant Melanoma ◽  
Autoimmune Disease ◽  
Interferon Therapy ◽  
Adjuvant Interferon

scholarly journals MALIGNANT MELANOMA OF UTERINE CERVIX IN A YOUNG FEMALE

2019 ◽  
pp. 1-2
Author(s):  
Purvi Rathod
Keyword(s):  
Malignant Melanoma ◽  
Uterine Cervix ◽  
Genital Tract ◽  
External Beam Radiotherapy ◽  
Female Genital Tract ◽  
Young Female ◽  
Rare Cancer ◽  
Female Genital

Malignant melanoma is a rare cancer, its incidence being 1% of all cancers. Malignant melanoma of the female genital tract is even rarer with incidence of 3% to 7% of all malignant melanomas. It usually occurs in postmenopausal women. We present a case of malignant melanoma of the uterine cervix in a multiparous premenopausal 29 year old female. She underwent a modified radical hysterectomy. She was stage III and was treated with external beam radiotherapy to the pelvis followed by brachytherapy. Since then the patient was on regular follow up until she developed lung metastasis. Malignant melanoma of the cervix has very less data in literature. Through this case report we will emphasize on the role of radiotherapy in malignant melanoma of uterine cervix

scholarly journals Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report

2020 ◽  
Vol 8 ◽  
pp. 2050313X2091002 ◽  
Author(s):  
Umut Selamet ◽  
Ramy M Hanna ◽  
Anthony Sisk ◽  
Lama Abdelnour ◽  
Lena Ghobry ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Interstitial Nephritis ◽  
Lupus Erythematosus ◽  
Kidney Biopsy ◽  
Kidney Injury ◽  
Acute Interstitial Nephritis ◽  
Systemic Lupus ◽  
Drug Induced ◽  
Systemic Manifestations

Drug-induced lupus erythematosus has features distinct from primary systemic lupus erythematosus. It can occur with a wide variety of agents that result in the generation of anti-histone or other types of antibodies. Systemic manifestations of drug-induced systemic lupus erythematosus may include renal dysfunction due to circulating immune complexes or due to other immune reactions to the culprit medication(s). Acute interstitial nephritis occurs due to DNA–drug or protein–drug complexes that trigger an allergic immune response. We report a patient who developed acute kidney injury, rash, and drug-induced systemic lupus diagnosed by serologies after starting chlorthalidone and amiodarone. A renal biopsy showed acute interstitial nephritis and not lupus-induced glomerulonephritis. It is important to note that systemic lupus erythematosus and acute interstitial nephritis can occur together, and this report highlights the role of the kidney biopsy in ascertaining the pathological diagnosis and outlining therapy in drug-induced lupus erythematosus.

scholarly journals Persistent Atrial Fibrillation: The Role of Left Atrial Posterior Wall Isolation and Ablation Strategies

2021 ◽  
Vol 10 (14) ◽  
pp. 3129
Author(s):  
Riyaz A. Kaba ◽  
Aziz Momin ◽  
John Camm
Keyword(s):  
Atrial Fibrillation ◽  
Left Atrial ◽  
Pulmonary Veins ◽  
Treatment Strategies ◽  
Persistent Atrial Fibrillation ◽  
Posterior Wall ◽  
Cardiovascular Death ◽  
Good Effect ◽  
Complex Forms

Atrial fibrillation (AF) is a global disease with rapidly rising incidence and prevalence. It is associated with a higher risk of stroke, dementia, cognitive decline, sudden and cardiovascular death, heart failure and impairment in quality of life. The disease is a major burden on the healthcare system. Paroxysmal AF is typically managed with medications or endocardial catheter ablation to good effect. However, a large proportion of patients with AF have persistent or long-standing persistent AF, which are more complex forms of the condition and thus more difficult to treat. This is in part due to the progressive electro-anatomical changes that occur with AF persistence and the spread of arrhythmogenic triggers and substrates outside of the pulmonary veins. The posterior wall of the left atrium is a common site for these changes and has become a target of ablation strategies to treat these more resistant forms of AF. In this review, we discuss the role of the posterior left atrial wall in persistent and long-standing persistent AF, the limitations of current endocardial-focused treatment strategies, and future perspectives on hybrid epicardial–endocardial approaches to posterior wall isolation or ablation.

scholarly journals Elucidating the role of Cavin1 in drug-induced long QT syndrome (diLQTS)

2021 ◽  
Vol 13 (2) ◽  
pp. 228-229
Author(s):  
Z. Al Sayed ◽  
C. Pereira ◽  
C. Jouve ◽  
J. Hulot
Keyword(s):  
Long Qt Syndrome ◽  
Long Qt ◽  
Drug Induced ◽  
Qt Syndrome
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