scholarly journals Effect of the Interindividual Variability on Computational Modeling of Transcranial Direct Current Stimulation

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Marta Parazzini ◽  
Serena Fiocchi ◽  
Ilaria Liorni ◽  
Paolo Ravazzani

Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low intensity, direct current to cortical areas facilitating or inhibiting spontaneous neuronal activity. This paper investigates how normal variations in anatomy may affect the current flow through the brain. This was done by applying electromagnetic computational methods to human models of different age and gender and by comparing the electric field and current density amplitude distributions within the tissues. Results of this study showed that the general trend of the spatial distributions of the field amplitude shares some gross characteristics among the different human models for the same electrode montages. However, the physical dimension of the subject and his/her morphological and anatomical characteristics somehow influence the detailed field distributions such as the field values.

2020 ◽  
Vol 30 (08) ◽  
pp. 2050038
Author(s):  
Mario Ortiz ◽  
Eduardo Iáñez ◽  
Jorge A. Gaxiola-Tirado ◽  
David Gutiérrez ◽  
José M. Azorín

The use of transcranial direct current stimulation (tDCS) has been related to the improvement of motor and learning tasks. The current research studies the effects of an asymmetric tDCS setup over brain connectivity, when the subject is performing a motor imagery (MI) task during five consecutive days. A brain–computer interface (BCI) based on electroencephalography is simulated in offline analysis to study the effect that tDCS has over different electrode configurations for the BCI. This way, the BCI performance is used as a validation index of the effect of the tDCS setup by the analysis of the classifier accuracy of the experimental sessions. In addition, the relationship between the brain connectivity and the BCI accuracy performance is analyzed. Results indicate that tDCS group, in comparison to the placebo sham group, shows a higher significant number of connectivity interactions in the motor electrodes during MI tasks and an increasing BCI accuracy over the days. However, the asymmetric tDCS setup does not improve the BCI performance of the electrodes in the intended hemisphere.


2021 ◽  
Vol 33 (1) ◽  
pp. 146-157
Author(s):  
Chong Zhao ◽  
Geoffrey F. Woodman

It is not definitely known how direct-current stimulation causes its long-lasting effects. Here, we tested the hypothesis that the long time course of transcranial direct-current stimulation (tDCS) is because of the electrical field increasing the plasticity of the brain tissue. If this is the case, then we should see tDCS effects when humans need to encode information into long-term memory, but not at other times. We tested this hypothesis by delivering tDCS to the ventral visual stream of human participants during different tasks (i.e., recognition memory vs. visual search) and at different times during a memory task. We found that tDCS improved memory encoding, and the neural correlates thereof, but not retrieval. We also found that tDCS did not change the efficiency of information processing during visual search for a certain target object, a task that does not require the formation of new connections in the brain but instead relies on attention and object recognition mechanisms. Thus, our findings support the hypothesis that direct-current stimulation modulates brain activity by changing the underlying plasticity of the tissue.


Metallomics ◽  
2018 ◽  
Vol 10 (3) ◽  
pp. 397-405
Author(s):  
Agata Ziomber ◽  
Artur Dawid Surowka ◽  
Lucyna Antkiewicz-Michaluk ◽  
Irena Romanska ◽  
Pawel Wrobel ◽  
...  

A new methodology for a combined Fe, Cu, Zn and neurometabolite analysis in the brain is reported.


Author(s):  
Jacky Au ◽  
Martin Buschkuehl ◽  
Susanne M. Jaeggi

The aim of this chapter is to contribute to the discussion of the cognitive neuroscience of brain stimulation. In doing so, the authors emphasize work from their own laboratory that focuses both on working memory training and transcranial direct current stimulation. Transcranial direct current stimulation is one of the most commonly used and extensively researched methods of transcranial electrical stimulation. The chapter focuses on implementation of transcranial direct current stimulation to enhance and inform research on working memory training, and not on the underlying mechanisms of transcranial direct current stimulation. Thus, while respecting the intricacies and unknowns of the inner workings of electrical stimulation on the brain, the chapter relies on the premise that transcranial direct current stimulation is able to directly affect the electrophysiological profile of the brain and provides evidence that this in turn can influence behavior given the right parameters.


2019 ◽  
Vol 12 (4) ◽  
pp. 1086-1088 ◽  
Author(s):  
Ashlee M. Hendy ◽  
Helen Macpherson ◽  
Nathan D. Nuzum ◽  
Paul A. Della Gatta ◽  
Sarah E. Alexander ◽  
...  

2019 ◽  
pp. 105971231987997 ◽  
Author(s):  
Atefeh Azarpaikan ◽  
HamidReza Taherii Torbati ◽  
Mehdi Sohrabi ◽  
Reza Boostani ◽  
Majid Ghoshuni

Transcranial direct current stimulation (tDCS) can shift neuronal membrane excitability by applying a weak slow electric current to the brain through the scalp. Attendant electroencephalography (EEG) can provide valuable information about the tDCS mechanisms. This study investigated the effects of anodal tDCS on parietal cortex and cerebellum activity to reveal possible modulation of spontaneous oscillatory brain activity. Timing of the tDCS priming protocol in relation to the intervention especially with respect to bimanual coordination task was also studied. EEG activity was measured in 120 healthy participants before and after sessions of anodal stimulation of the parietal cortex and cerebellum to detect the tDCS-induced alterations. Variations of the delta, theta, alpha, beta, and sensorimotor rhythm (SMR) power bands were analyzed using a MATLAB program. The results showed that anodal parietal and cerebellar tDCS cause changes in brain wave frequencies. They also showed an increase in alpha, beta, and SMR power bands during stimulation sessions for during stimulation parietal group ( p ≤ .01). Also, theta, alpha, beta, and SMR power bands were increased in during stimulation cerebellum group in stimulation sessions and 48 h later ( p ≤ .01). Moreover, the results revealed that the tDCS intervention led to a variety of activations in some areas of the brain. Altogether, the cerebellar tDCS during motor task had a significant improvement in off-line learning.


2016 ◽  
Vol 127 (4) ◽  
pp. 2119-2126 ◽  
Author(s):  
Georgios Naros ◽  
Marc Geyer ◽  
Susanne Koch ◽  
Lena Mayr ◽  
Tabea Ellinger ◽  
...  

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