scholarly journals Costello Syndrome with Severe Nodulocystic Acne: Unexpected Significant Improvement of Acanthosis Nigricans after Oral Isotretinoin Treatment

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Leelawadee Sriboonnark ◽  
Harleen Arora ◽  
Leyre Falto-Aizpurua ◽  
Sonal Choudhary ◽  
Elizabeth Alvarez Connelly

We report the case of 17-year-old female diagnosed with Costello syndrome. Genetic testing provided a proof with G12S mutation in the HRAS gene since 3 years of age with a presentation of severe nodulocystic acne on her face. After 2 months of oral isotretinoin treatment, improvement in her acne was observed. Interestingly, an unexpected significant improvement of acanthosis nigricans on her neck and dorsum of her hands was found as well. We present this case as a successful treatment option by using oral isotretinoin for the treatment of acanthosis nigricans in Costello syndrome patients.

2017 ◽  
Vol 3 (2) ◽  
pp. 111-113 ◽  
Author(s):  
Rodrigo Pirmez ◽  
Bruna Duque-Estrada ◽  
Taynara Barreto ◽  
Danielle C. Quintella ◽  
Tullia Cuzzi

2013 ◽  
Vol 3 (S3) ◽  
Author(s):  
E Dehlink ◽  
C Bannert ◽  
T Eiwegger ◽  
S Diesner ◽  
S Gruber ◽  
...  

2021 ◽  
pp. 29-30
Author(s):  
Deepika Sharma ◽  
Tarun Gaur ◽  
Karunakaran Keshav

With the advancement in the dental implant treatment, many new innovative improvements have been developed in the designs and components of implants. These improvements helps to handle the compromising situations where sometimes the good treatment option can become more challenging. One of the such grueling condition is implant placement in the anterior maxilla where dentist has to fulll both aesthetic and functional demand. Many aesthetic failures of implant have been reported in the literature in the anterior maxilla. One of them is placing implant in sites with deciency of facial bone thickness which sometimes resulted in malposition of implant. This case report discusses about the prosthodontic correction of malpositioned implant in the anterior maxilla by using castable abutment. The use of castable abutment is concluded as successful treatment option for complex misaligned and malposed single dental implant.


2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Márcio de Carvalho Formiga ◽  
Magda Nagasawa ◽  
Jamil Awad Shibli

Mandibular full-arch restoration is a good and successful treatment option for totally edentulous patients. In the past years, several studies have described the placement of 4 to 6 implants to restore this type of case; however, an option using 3 dental implants placed in strategic and specific positions could also be an alternative. Therefore, this case report describes a full-arch rehabilitation on 3 straight, immediately loaded implants after 8 years of follow-up. The restoration presented no biological or technical complications during this follow-up period, showing that an adequate treatment plan was able to allow good results using this treatment option.


2019 ◽  
Vol 11 (4) ◽  
Author(s):  
Kelly Scott ◽  
Donald Dulle ◽  
Genaro Garcia ◽  
Jonathan A. Flug ◽  
Anikar Chhabra

Injuries to the hand and digits are common in football players. To our knowledge, there have been no reports on multiple flexor pulley ruptures in football players treated non-operatively through splinting and taping techniques. A 22-year old collegiate defensive lineman sustained an injury resulting in complete disruption of the annular 2, 3, 4, and cruciate 1 and 2 pulleys. The patient was successfully treated with serial custom splints for 12 weeks. Our splinting and taping techniques and timing of these have not been previously described. This case illustrates a successful treatment option in football players with multiple flexor pulley ruptures.


2001 ◽  
Vol 40 (3) ◽  
pp. 203-205 ◽  
Author(s):  
Alireza Firooz ◽  
Mehdi Rashighi Firoozabadi ◽  
Yahya Dowlati

2021 ◽  
pp. 135965352110598
Author(s):  
Larry Napolitano ◽  
Liesl Schroedl ◽  
Alexander Kerman ◽  
Christopher R Shea

Cidofovir is a broad-spectrum antiviral agent that has shown efficacy against skin lesions caused by human papillomavirus (HPV). We present a case of extensive verruca vulgaris lesions refractory to imiquimod that was responsive to topical cidofovir therapy, and analyze other case series in the literature of successful treatment of benign HPV-associated skin lesions with topical cidofovir. Topical cidofovir’s favorable response rate and tolerability make it a useful treatment option for patients of differing ages and immune status who have nonmalignant HPV-associated skin lesions and desire topical therapy.


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