scholarly journals Biomarkers of Eating Disorders Using Support Vector Machine Analysis of Structural Neuroimaging Data: Preliminary Results

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Antonio Cerasa ◽  
Isabella Castiglioni ◽  
Christian Salvatore ◽  
Angela Funaro ◽  
Iolanda Martino ◽  
...  

Presently, there are no valid biomarkers to identify individuals with eating disorders (ED). The aim of this work was to assess the feasibility of a machine learning method for extracting reliable neuroimaging features allowing individual categorization of patients with ED. Support Vector Machine (SVM) technique, combined with a pattern recognition method, was employed utilizing structural magnetic resonance images. Seventeen females with ED (six with diagnosis of anorexia nervosa and 11 with bulimia nervosa) were compared against 17 body mass index-matched healthy controls (HC). Machine learning allowed individual diagnosis of ED versus HC with an Accuracy ≥ 0.80. Voxel-based pattern recognition analysis demonstrated that voxels influencing the classification Accuracy involved the occipital cortex, the posterior cerebellar lobule, precuneus, sensorimotor/premotor cortices, and the medial prefrontal cortex, all critical regions known to be strongly involved in the pathophysiological mechanisms of ED. Although these findings should be considered preliminary given the small size investigated, SVM analysis highlights the role of well-known brain regions as possible biomarkers to distinguish ED from HC at an individual level, thus encouraging the translational implementation of this new multivariate approach in the clinical practice.

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Elisa Veronese ◽  
Umberto Castellani ◽  
Denis Peruzzo ◽  
Marcella Bellani ◽  
Paolo Brambilla

In recent years, machine learning approaches have been successfully applied for analysis of neuroimaging data, to help in the context of disease diagnosis. We provide, in this paper, an overview of recent support vector machine-based methods developed and applied in psychiatric neuroimaging for the investigation of schizophrenia. In particular, we focus on the algorithms implemented by our group, which have been applied to classify subjects affected by schizophrenia and healthy controls, comparing them in terms of accuracy results with other recently published studies. First we give a description of the basic terminology used in pattern recognition and machine learning. Then we separately summarize and explain each study, highlighting the main features that characterize each method. Finally, as an outcome of the comparison of the results obtained applying the described different techniques, conclusions are drawn in order to understand how much automatic classification approaches can be considered a useful tool in understanding the biological underpinnings of schizophrenia. We then conclude by discussing the main implications achievable by the application of these methods into clinical practice.


2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
ZhiHong Chen ◽  
Tao Yan ◽  
ErLei Wang ◽  
Hong Jiang ◽  
YiQian Tang ◽  
...  

Utilizing neuroimaging and machine learning (ML) to differentiate schizophrenia (SZ) patients from normal controls (NCs) and for detecting abnormal brain regions in schizophrenia has several benefits and can provide a reference for the clinical diagnosis of schizophrenia. In this study, structural magnetic resonance images (sMRIs) from SZ patients and NCs were used for discriminative analysis. This study proposed an ML framework based on coarse-to-fine feature selection. The proposed framework used two-sample t-tests to extract the differences between groups first, then further eliminated the nonrelevant and redundant features with recursive feature elimination (RFE), and finally utilized the support vector machine (SVM) to learn the decision models with selected gray matter (GM) and white matter (WM) features. Previous studies have tended to report differences at the group level instead of at the individual level and cannot be widely applied. The method proposed in this study extends the diagnosis to the individual level and has a higher recognition rate than previous methods. The experimental results of this study demonstrate that the proposed framework distinguishes SZ patients from NCs, with the highest classification accuracy reaching over 85%. The identified biomarkers are also consistent with previous literature findings. As a universal method, the proposed framework can be extended to diagnose other diseases.


2011 ◽  
Vol 120 ◽  
pp. 190-194 ◽  
Author(s):  
Qiang Shao ◽  
Chang Jian Feng

To distinguish chatter gestation, chatter recognition method based on hybrid PCA(Principal Compenent Analysis) and SVM(Support Vector Machine) is proposed for dynamic patterns of chatter gestation in cutting process. At first, FFT features are extracted from the vibration signal of cutting process, then FFT vectors are presorted and introduced to PCA-SVM for machine learning and classification. Finally the results of chatter gestation recognition and chatter prediction experiments are presented and show that the method proposed is effective.


2019 ◽  
Vol 67 (6) ◽  
pp. 1991-2003 ◽  
Author(s):  
Edyta Puskarczyk

Abstract Unconventional oil and gas reservoirs from the lower Palaeozoic basin at the western slope of the East European Craton were taken into account in this study. The aim was to supply and improve standard well logs interpretation based on machine learning methods, especially ANNs. ANNs were used on standard well logging data, e.g. P-wave velocity, density, resistivity, neutron porosity, radioactivity and photoelectric factor. During the calculations, information about lithology or stratigraphy was not taken into account. We apply different methods of classification: cluster analysis, support vector machine and artificial neural network—Kohonen algorithm. We compare the results and analyse obtained electrofacies. Machine learning method–support vector machine SVM was used for classification. For the same data set, SVM algorithm application results were compared to the results of the Kohonen algorithm. The results were very similar. We obtained very good agreement of results. Kohonen algorithm (ANN) was used for pattern recognition and identification of electrofacies. Kohonen algorithm was also used for geological interpretation of well logs data. As a result of Kohonen algorithm application, groups corresponding to the gas-bearing intervals were found. Analysis showed diversification between gas-bearing formations and surrounding beds. It is also shown that internal diversification in gas-saturated beds is present. It is concluded that ANN appeared to be a useful and quick tool for preliminary classification of members and gas-saturated identification.


Author(s):  
Gharib M Subhi ◽  
Azeddine Messikh

Machine learning plays a key role in many applications such as data mining and image recognition.Classification is one subcategory under machine learning. In this paper we propose a simple quantum circuitbased on the nearest mean classifier to classified handwriting characters. Our circuit is a simplified circuit fromthe quantum support vector machine [Phys. Rev. Lett. 114, 140504 (2015)] which uses quantum matrix inversealgorithm to find optimal hyperplane that separated two different classes. In our case the hyperplane is foundusing projections and rotations on the Bloch sphere.


2011 ◽  
Vol 69 ◽  
pp. 88-92
Author(s):  
Qiang Shao ◽  
Chang Jian Feng ◽  
Wen Long Li

To distinguish chatter gestation, chatter recognition method based on hybrid KPCA(Kernel Principal Compenent Analysis) and SVM(Support Vector Machine) is proposed for dynamic patterns of chatter gestation in cutting process. At first, FFT features are extracted from the vibration signal of cutting process, then FFT vectors are presorted and introduced to KPCA-SVM for machine learning and classification. Finally the results of chatter gestation recognition and chatter prediction experiments are presented and show that the method proposed is effective.


2020 ◽  
Vol 25 (1) ◽  
pp. 24-38
Author(s):  
Eka Patriya

Saham adalah instrumen pasar keuangan yang banyak dipilih oleh investor sebagai alternatif sumber keuangan, akan tetapi saham yang diperjual belikan di pasar keuangan sering mengalami fluktuasi harga (naik dan turun) yang tinggi. Para investor berpeluang tidak hanya mendapat keuntungan, tetapi juga dapat mengalami kerugian di masa mendatang. Salah satu indikator yang perlu diperhatikan oleh investor dalam berinvestasi saham adalah pergerakan Indeks Harga Saham Gabungan (IHSG). Tindakan dalam menganalisa IHSG merupakan hal yang penting dilakukan oleh investor dengan tujuan untuk menemukan suatu trend atau pola yang mungkin berulang dari pergerakan harga saham masa lalu, sehingga dapat digunakan untuk memprediksi pergerakan harga saham di masa mendatang. Salah satu metode yang dapat digunakan untuk memprediksi pergerakan harga saham secara akurat adalah machine learning. Pada penelitian ini dibuat sebuah model prediksi harga penutupan IHSG menggunakan algoritma Support Vector Regression (SVR) yang menghasilkan kemampuan prediksi dan generalisasi yang baik dengan nilai RMSE training dan testing sebesar 14.334 dan 20.281, serta MAPE training dan testing sebesar 0.211% dan 0.251%. Hasil penelitian ini diharapkan dapat membantu para investor dalam mengambil keputusan untuk menyusun strategi investasi saham.


2021 ◽  
Vol 186 (Supplement_1) ◽  
pp. 445-451
Author(s):  
Yifei Sun ◽  
Navid Rashedi ◽  
Vikrant Vaze ◽  
Parikshit Shah ◽  
Ryan Halter ◽  
...  

ABSTRACT Introduction Early prediction of the acute hypotensive episode (AHE) in critically ill patients has the potential to improve outcomes. In this study, we apply different machine learning algorithms to the MIMIC III Physionet dataset, containing more than 60,000 real-world intensive care unit records, to test commonly used machine learning technologies and compare their performances. Materials and Methods Five classification methods including K-nearest neighbor, logistic regression, support vector machine, random forest, and a deep learning method called long short-term memory are applied to predict an AHE 30 minutes in advance. An analysis comparing model performance when including versus excluding invasive features was conducted. To further study the pattern of the underlying mean arterial pressure (MAP), we apply a regression method to predict the continuous MAP values using linear regression over the next 60 minutes. Results Support vector machine yields the best performance in terms of recall (84%). Including the invasive features in the classification improves the performance significantly with both recall and precision increasing by more than 20 percentage points. We were able to predict the MAP with a root mean square error (a frequently used measure of the differences between the predicted values and the observed values) of 10 mmHg 60 minutes in the future. After converting continuous MAP predictions into AHE binary predictions, we achieve a 91% recall and 68% precision. In addition to predicting AHE, the MAP predictions provide clinically useful information regarding the timing and severity of the AHE occurrence. Conclusion We were able to predict AHE with precision and recall above 80% 30 minutes in advance with the large real-world dataset. The prediction of regression model can provide a more fine-grained, interpretable signal to practitioners. Model performance is improved by the inclusion of invasive features in predicting AHE, when compared to predicting the AHE based on only the available, restricted set of noninvasive technologies. This demonstrates the importance of exploring more noninvasive technologies for AHE prediction.


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