scholarly journals The Relationship between Metabolic Control and Growth in Children with Type I Diabetes Mellitus in Southwest of Iran

Scientifica ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Shide Assar ◽  
Koroush Riahi ◽  
Shiva Bashirnezhad ◽  
Leila Yazdanpanah ◽  
Seyed Mahmoud Latifi
Keyword(s):  
Metabolic Control ◽  
Type I Diabetes ◽  
Physical Growth ◽  
Average Weight ◽  
Average Height ◽  
Type I ◽  
Poor Metabolic Control ◽  
Significant Difference ◽  
Southwest Of Iran ◽  
The Relationship

Background. Metabolic control is an important factor in growth of children with type I diabetes. This study assessed the relationship between growth and metabolic control in such children.Materials and Methods. 83 children with diabetes were studied. They were examined for weight and height gain and HbA1C was quantified every 3 months for one year. The growth process was studied in patients who were divided into 3 groups according to their HbA1C amounts, consisting of good, intermediate, and poor metabolic control.Results. Mean age of cases was 7.6 ± 2. The presenting sign at the onset of disease was diabetic ketoacidosis in 44.6%. The average HbA1C amount was 8.89%. The average weight SDS at diagnosis was −0.18 and at the end of the study was 0.45 (P<0.001). The average height SDS at diagnosis was −0.04 and at the end of the study was −0.07 (P=0.64). A significant difference in weight SDS changes was only seen between patients with good and poor metabolic control (P=0.04).Conclusion. Poor metabolic control can decrease height growth but has minimal influence on weight. Metabolic control was not the only predictive factor of physical growth in children with diabetes.

scholarly journals Obstetric Management of a Pregnant With Type I Diabetes and Poor Metabolic Control - A Case Report

2017 ◽  
Vol 04 (05) ◽  
Author(s):  
Adriano Soares ◽  
Humberto S Machado ◽  
Diana Coelho ◽  
Claudia Guerra ◽  
Pedro Oliveira ◽  
...  
Keyword(s):  
Case Report ◽  
Metabolic Control ◽  
Type I Diabetes ◽  
Type I ◽  
Poor Metabolic Control ◽  
Obstetric Management

scholarly journals ANALYSIS OF THE RELATIONSHIP OF BEHAVIORAL HABITS AND PERIODONTAL STATUS AND ORAL HEALTH IN CHILDREN OF PRIMARY SCHOOL AGE WITH DIABETES MELLITUS TYPE I AND PARENTS RESULTS USING DENTAL QUESTIONNAIRE

2021 ◽  
Vol 21 (1) ◽  
pp. 71-75
Author(s):  
I.O. Kuz
Keyword(s):  
Diabetes Mellitus ◽  
Type I Diabetes ◽  
Periodontal Diseases ◽  
Dental Health ◽  
Subsequent Development ◽  
Type I Diabetes Mellitus ◽  
Type I ◽  
Healthy Children ◽  
Significant Difference ◽  
The Relationship

Type I diabetes mellitus is an autoimmune disease in genetically susceptible individuals that leads to the destruction of pancreatic β-cells with the subsequent development of absolute insulin deficiency. The presence of type I diabetes mellitus in children is the main risk factor for the onset of inflammatory periodontal diseases. When comparing the values of the hygiene indices according to Fedorov - Volodkina and the simplified OHI-S index (Green-Vermillion), a statistically significant difference (p ≤ 0.05) was found when comparing groups 1 and 2, 3 and 4, 2 and 4, 1 and 4 and was not found (p≥0.05) between groups 1 and 3 (in children with healthy gums with and without type I diabetes). We also found a statistically significant difference between patients with type 1 diabetes and healthy children in periodontal indices and gingival indices. Inflammatory processes in the periodontium of children with diabetes are elevated, so it is very important to recognize and diagnose them as soon as possible. Based on the answers to the "Dental questionnaire for children and parents" (certificate of copyright registration, registration date 01.24.2020), the relationship between behavior patterns, parent’s habits and the dental status of schoolchildren was quite informative, it opens up the possibility of early detection of problems in medical and preventive work among the children. We made the following conclusions: by questioning parents, we can reveal their attitude to their dental health and dental health of children, as well as to determine in more detail the risk factors for periodontal disease and dental diseases in general. Despite the availability of educational programs and routine dental examinations in kindergartens and schools (they are mainly focused on the formation of a conscious attitude to dental health directly in children), the dental literacy of parents should be increased.

scholarly journals Perioperative Outcomes Following Kidney-Pancreas Transplantation in Alberta, Canada: Research Letter

2021 ◽  
Vol 8 ◽  
pp. 205435812110293
Author(s):  
Danielle E. Fox ◽  
Robert R. Quinn ◽  
Paul E. Ronksley ◽  
Tyrone G. Harrison ◽  
Hude Quan ◽  
...  
Keyword(s):  
Patient Outcomes ◽  
Postoperative Care ◽  
Pancreas Transplantation ◽  
Type I Diabetes ◽  
Small Sample Size ◽  
Small Sample ◽  
Perioperative Outcomes ◽  
Type I ◽  
Patient Safety Indicators ◽  
Significant Difference

Background: Simultaneous kidney-pancreas transplantation (SPK) has benefits for patients with kidney failure and type I diabetes mellitus, but is associated with greater perioperative risk compared with kidney-alone transplantation. Postoperative care settings for SPK recipients vary across Canada and may have implications for patient outcomes and hospital resource use. Objective: To compare outcomes following SPK transplantation between patients receiving postoperative care in the intensive care unit (ICU) compared with the ward. Design: Retrospective cohort study using administrative health data. Setting: In Alberta, the 2 transplant centers (Calgary and Edmonton) have different protocols for routine postoperative care of SPK recipients. In Edmonton, SPK recipients are routinely transferred to the ICU, whereas in Calgary, SPK recipients are transferred to the ward. Patients: 129 adult SPK recipients (2002-2019). Measurements: Data from the Canadian Institute for Health Information Discharge Abstract Database (CIHI-DAD) were used to identify SPK recipients (procedure codes) and the outcomes of inpatient mortality, length of initial hospital stay (LOS), and the occurrence of 16 different patient safety indicators (PSIs). Methods: We followed SPK recipients from the admission date of their transplant hospitalization until the first of hospital discharge or death. Unadjusted quantile regression was used to determine differences in LOS, and age- and sex-adjusted marginal probabilities were used to determine differences in PSIs between centers. Results: There were no perioperative deaths and no major differences in the demographic characteristics between the centers. The majority of the SPK transplants were performed in Edmonton (n = 82, 64%). All SPK recipients in Edmonton were admitted to the ICU postoperatively, compared with only 11% in Calgary. There was no statistically significant difference in the LOS or probability of a PSI between the 2 centers (LOS for Edmonton vs Calgary:16 vs 13 days, P = .12; PSIs for Edmonton vs Calgary: 60%, 95% confidence interval [CI] = 0.50-0.71 vs 44%, 95% CI = 0.29-0.59, P = .08). Limitations: This study was conducted using administrative data and is limited by variable availability. The small sample size limited precision of estimated differences between type of postoperative care. Conclusions: Following SPK transplantation, we found no difference in inpatient outcomes for recipients who received routine postoperative ICU care compared with ward care. Further research using larger data sets and interventional study designs is needed to better understand the implications of postoperative care settings on patient outcomes and health care resource utilization.

A program to reduce onset distress in unselected type I diabetic patients: effects on psychological variables and metabolic control

1995 ◽  
Vol 132 (5) ◽  
pp. 580-586 ◽  
Author(s):  
K Spiess ◽  
G Sachs ◽  
P Pietschmann ◽  
R Prager
Keyword(s):  
Patient Education ◽  
Metabolic Control ◽  
Type I Diabetes ◽  
Intensive Treatment ◽  
Medical Psychology ◽  
Diabetic Patients ◽  
Type I ◽  
Psychological Variables ◽  
Reduction Program

Spiess K, Sachs G, Pietschmann P, Prager R. A program to reduce onset distress in unselected type I diabetic patients: effects on psychological variables and metabolic control. Eur J Endocrinol 1995;132:580–6. ISSN 0804–4643 This paper reports the results of a prospective controlled trial of a program addressing reduction of onset distress and better future adaptation in adults who were enrolled at the time of diagnosis of type I diabetes mellitus. Patients were assigned randomly to either standard intensive treatment and patient education with the distress reduction program (N = 10) or to standard intensive treatment and patient education without this program (N = 13). Prospective follow-up of patients with multiple validated measures of treatment outcome showed less anxious coping behavior, less depression and less denial at the 9-month follow-up and less denial at the 15-month follow-up in the group with the distress reduction program, but no differences in metabolic control between the two groups at any time. We conclude that our program has a positive impact on the crisis at diabetes onset; the lower denial in the treatment group may lead to improved regimen adherence in the long term. Klaus Spiess, Institute of Medical Psychology, University of Vienna, Severingasse 9, A-1090-Vienna, Austria

EVALUATION OF MEAT IN THE INFANT DIET

PEDIATRICS ◽  
1952 ◽  
Vol 10 (4) ◽  
pp. 463-473
Author(s):  
HOWARD M. JACOBS ◽  
GEORGE S. GEORGE
Keyword(s):  
Total Protein ◽  
Infant Nutrition ◽  
Physical Growth ◽  
Morbidity Rate ◽  
Control Group ◽  
Average Weight ◽  
Protein Requirements ◽  
Protein Levels ◽  
Young Infants ◽  
Significant Difference

A commercially prepared lean meat was fed to young infants as a supplement to a diet already adequate in all food factors. In those infants first fed meat under 2 months of age, there was improvement in physical growth as determined by weight and height measurements. The same group demonstrated an improvement in hemoglobin levels; the elimination of the physiologic drop in total protein levels of the serum, with a prompt sustained rise in values, the greater part of which was composed of the globulin fraction. In those infants first fed meat after 2 months of age, there was a slight improvement in average weight gain, but no significant difference was noted in other body measurements, total protein, albumin or globulin fractions, or hemoglobin levels. Illness rates for the two years of the study demonstrated a 40% lower morbidity rate in the meat-fed group as compared to the control group. In striving for the optimum in infant nutrition protein requirements should be evaluated both quantitatively and qualitatively.

scholarly journals Adult cognitive outcomes in phenylketonuria: explaining causes of variability beyond average Phe levels

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Cristina Romani ◽  
Filippo Manti ◽  
Francesca Nardecchia ◽  
Federica Valentini ◽  
Nicoletta Fallarino ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Metabolic Control ◽  
Individual Variability ◽  
Cognitive Outcomes ◽  
Cognitive Tasks ◽  
Cognitive Measures ◽  
Poor Metabolic Control ◽  
European Guidelines ◽  
Metabolic Variables ◽  
The Relationship

Abstract Objective The objective was to deepen the understanding of the causes of individual variability in phenylketonuria (PKU) by investigating which metabolic variables are most important for predicting cognitive outcomes (Phe average vs Phe variation) and by assessing the risk of cognitive impairment associated with adopting a more relaxed approach to the diet than is currently recommended. Method We analysed associations between metabolic and cognitive measures in a mixed sample of English and Italian early-treated adults with PKU (N = 56). Metabolic measures were collected through childhood, adolescence and adulthood; cognitive measures were collected in adulthood. Metabolic measures included average Phe levels (average of median values for each year in a given period) and average Phe variations (average yearly standard deviations). Cognition was measured with IQ and a battery of cognitive tasks. Results Phe variation was as important, if not more important, than Phe average in predicting adult outcomes and contributed independently. Phe variation was particularly detrimental in childhood. Together, childhood Phe variation and adult Phe average predicted around 40% of the variation in cognitive scores. Poor cognitive scores (> 1 SD from controls) occurred almost exclusively in individuals with poor metabolic control and the risk of poor scores was about 30% higher in individuals with Phe values exceeding recommended thresholds. Conclusions Our results provide support for current European guidelines (average Phe value = < 360 μmol/l in childhood; = < 600 μmo/l from 12 years onwards), but they suggest an additional recommendation to maintain stable levels (possibly Phe SD = < 180 μmol/l throughout life). Public significance statements We investigated the relationship between how well people with phenylketonuria control blood Phe throughout their life and their ability to carry out cognitive tasks in adulthood. We found that avoiding blood Phe peaks was as important if not more important that maintaining average low Phe levels. This was particularly essential in childhood. We also found that blood Phe levels above recommended European guidelines was associated with around 30% increase in the risk of poor cognitive outcomes.

Psychological Stress and Metabolic Control in Patients with Type I Diabetes Mellitus

1986 ◽  
Vol 314 (17) ◽  
pp. 1078-1084 ◽  
Author(s):  
Friedrich W. Kemmer ◽  
Rolf Bisping ◽  
Hans J. Steingrüber ◽  
Helmut Baar ◽  
Frank Hardtmann ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Control ◽  
Psychological Stress ◽  
Type I Diabetes ◽  
Type I Diabetes Mellitus ◽  
Type I
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