scholarly journals Dramatic Improvement of Subcutaneous Calcinosis by Intermittent, High-Dose Etidronate plus Cimetidine in a Patient with Juvenile Dermatomyositis

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Takayuki Wakabayashi ◽  
Noriko Sasaki ◽  
Naofumi Chinen ◽  
Yasuo Suzuki

A 17-year-old boy with juvenile dermatomyositis presented with typical skin symptoms, mild myositis, and bilateral lower limb calcinosis. His skin and muscle symptoms responded to treatment with prednisolone and azathioprine. However, calcinosis did not improve, and the patient had a limited range of knee joint motion and resultant disturbance of daily activities. Cimetidine was combined with intermittent administration of high-dose etidronate, leading to marked improvement of both subcutaneous and muscular calcinosis with no skeletal adverse reactions during a long treatment period exceeding 5 years. As a result, the range of knee joint motion has increased and performance of daily activities has improved.

Author(s):  
Hongsheng Wang ◽  
Naiquan Nigel Zheng

The anterior cruciate ligament reconstructed (ACL-R) knees suffer from a higher risk for osteoarthritis (OA) which is the major leading cause of disability[1]. In order to understand the mechanism of knee injury and the development of OA, precise 3-D knee joint motion is often determined by invasive, or radioactive approaches[2]. For studying daily activities like walking which has larger range of motion (ROM), the skin marker-based technique remains the only feasible way[3].


The Knee ◽  
2007 ◽  
Vol 14 (5) ◽  
pp. 385-389 ◽  
Author(s):  
Berry Cleffken ◽  
Gerard van Breukelen ◽  
Peter Brink ◽  
Henk van Mameren ◽  
Steven Olde Damink

1997 ◽  
Vol 30 (7) ◽  
pp. 729-732 ◽  
Author(s):  
C. Reinschmidt ◽  
A.J. van den Bogert ◽  
B.M. Nigg ◽  
A. Lundberg ◽  
N. Murphy

2008 ◽  
Vol 2008.47 (0) ◽  
pp. 121-122
Author(s):  
Naohiro Taniguchi ◽  
Kensaku Kawakami ◽  
Takumi Ino ◽  
Toru Miyoshi ◽  
Toshinori Yoshida ◽  
...  

2008 ◽  
Vol 41 (8) ◽  
pp. 1632-1638 ◽  
Author(s):  
A.J. van den Bogert ◽  
C. Reinschmidt ◽  
A. Lundberg

2013 ◽  
Vol 16 (3) ◽  
pp. 119-138 ◽  
Author(s):  
Oliver Sander ◽  
Corinna Klapproth ◽  
Jonathan Youett ◽  
Ralf Kornhuber ◽  
Peter Deuflhard

1990 ◽  
Vol 18 (2) ◽  
pp. 169-176 ◽  
Author(s):  
Lars Engebretsen ◽  
William D. Lew ◽  
Jack L. Lewis ◽  
Robert E. Hunter

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