scholarly journals Does Posterior Capsule Opacification Affect the Results of Diagnostic Technologies to Evaluate the Retina and the Optic Disc?

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Jose Javier Garcia-Medina ◽  
Monica del Rio-Vellosillo ◽  
Vicente Zanon-Moreno ◽  
Enrique Santos-Bueso ◽  
Roberto Gallego-Pinazo ◽  
...  

The visual outcome obtained after cataract removal may progressively decline because of posterior capsular opacification (PCO). This condition can be treated by creating an opening in the posterior lens capsule by Nd:YAG laser capsulotomy. PCO optical imperfections cause several light reflection, refraction, and diffraction phenomena, which may interfere with the functional and structural tests performed in different ocular locations for the diagnosis and follow-up of ocular disease, like macular and optic nerve diseases. Some parameters measured by visual field examinations, scanning laser polarimetry, and optical coherence tomography (OCT) have changed after PCO removal. Imaging quality also changes following capsulotomy. Consequently, the results of ancillary tests in pseudophakic eyes for studying ocular diseases like glaucoma or maculopathies should be correlated with other clinical examinations, for example, slit-lamp biomicroscopy or funduscopy. If PCO is clinically significant, a new baseline should be set for future comparisons following capsulotomy when using automated perimetry and scanning laser polarimetry. To perform OCT in the presence of PCO, reliable examinations (considering signal strength) apparently guarantee that measurements are not influenced by PCO.

2005 ◽  
Vol 244 (4) ◽  
pp. 520-523 ◽  
Author(s):  
José Javier García Medina ◽  
Manuel García Medina ◽  
Mohamed Shahin ◽  
María Dolores Pinazo Durán

2006 ◽  
Vol 244 (11) ◽  
pp. 1398-1405 ◽  
Author(s):  
José Javier García-Medina ◽  
Manuel García-Medina ◽  
Samuel González-Ocampo Dorta ◽  
María Dolores Pinazo-Durán ◽  
Roberto Gallego-Pinazo ◽  
...  

2007 ◽  
Vol 16 (1) ◽  
pp. 112-116 ◽  
Author(s):  
Christopher J. Brittain ◽  
Kenneth C. S. Fong ◽  
Christopher C. Hull ◽  
Ian H. Gillespie

2007 ◽  
Vol 35 (5) ◽  
pp. 414-420 ◽  
Author(s):  
Jose J Garcia-Medina ◽  
Manuel Garcia-Medina ◽  
Vicente C Zanon-Moreno ◽  
Roberto Gallego-Pinazo ◽  
Sheila Pons-Vazquez ◽  
...  

Author(s):  
Mael Lever ◽  
Christian Halfwassen ◽  
Jan Darius Unterlauft ◽  
Nikolaos E. Bechrakis ◽  
Anke Manthey ◽  
...  

Abstract Purpose A central diagnostic tool in adult glaucoma is the peripapillary retinal nerve fibre layer (pRNFL) thickness. It can be assessed by scanning laser polarimetry (SLP) or optical coherence tomography (OCT). However, studies investigating the relevance of pRNFL measurements in children are rare. This study aims to compare the glaucoma diagnosing ability of SLP and OCT pRNFL thickness measurements in a paediatric population. Methods This retrospective study included 105 children (glaucoma: 22 (21.0%); healthy glaucoma suspects: 83 (79.0%)) aged 4–18 years, examined with SLP (GDxPro/ECC, Carl Zeiss Meditec) and spectral-domain OCT (SPECTRALIS®, Heidelberg Engineering). The thickness of pRNFL sectors was compared between diseased and healthy participants. Areas under the receiver-operating characteristic curves (AUC) and logistic regression results were used to compare the glaucoma discriminative capacity between SLP and OCT measurements. Results Using OCT, pRNFL thickness was decreased in the superior, nasal, and inferior quadrants of glaucoma patients compared to healthy controls (P < 0.001, each). With SLP, such a difference was only observed in the inferior quadrant (P = 0.011). A correlation between glaucoma diagnosis and OCT-measured pRNFL thickness was found in all quadrants (P < 0.001) other than the temporal. With SLP, a correlation was found for the total average thickness (P = 0.037) and inferior quadrant (P = 0.0019). Finally, the AUCs of OCT measurements were markedly higher than those of SLP (e.g., inferior quadrant: OCT 0.83, SLP 0.68). Conclusion pRNFL thickness measurements using both OCT and SLP, correlate notably with the presence of glaucoma. In general, the diagnostic performance of pRNFL thickness measurements seems higher for OCT than for SLP. Thus, pRNFL thickness measurements could provide important information, complementing conventional clinical and functional parameters in the diagnostic process of paediatric glaucoma.


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