scholarly journals Spiral Enteroscopy Utilizing Capsule Location Index for Achieving High Diagnostic and Therapeutic Yield

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Rohan Mandaliya ◽  
Jason Korenblit ◽  
Brendan O’Hare ◽  
Anastasia Shnitser ◽  
Ramalinga Kedika ◽  
...  
Keyword(s):  
Small Bowel ◽  
Diagnostic Yield ◽  
Small Bowel Transit ◽  
Small Bowel Transit Time ◽  
Academic Center ◽  
Predictive Role ◽  
Spiral Enteroscopy ◽  
Vascular Ectasias ◽  
Initial Route

Background and Aim. Spiral enteroscopy (SE) is a new small bowel endoscopic technique. Our aim is to review the diagnostic and therapeutic yield, safety of SE, and the predictive role of prior capsule endoscopy (CE) at an academic center. Methods. A retrospective review of patients undergoing SE after prior CE between 2008 and 2013 was performed. Capsule location index (CLI) was defined as the fraction of total small bowel transit time when the lesion was seen on CE. Results. A total of 174 SEs were performed: antegrade (147) and retrograde (27). Abnormalities on SE were detected in 65% patients. The procedure was safe in patients with surgically altered bowel anatomy (n=12). The diagnostic yield of antegrade SE decreased with increasing CLI range. The diagnostic yield of retrograde SE decreased on decreasing CLI range. A CLI cutoff of 0.6 was derived that determined the initial route of SE. Vascular ectasias seen on CE were detected in 83% cases on SE; p<0.01. Conclusions. SE is safe with a high diagnostic and therapeutic yield. CLI is predictive of the success of SE and determines the best route of SE. The type of small bowel pathology targeted by SE may affect its utility and yield.

scholarly journals The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Majid Alsahafi ◽  
Paula Cramer ◽  
Nazira Chatur ◽  
Fergal Donnellan
Keyword(s):  
Small Bowel ◽  
Transit Time ◽  
Capsule Endoscopy ◽  
Small Bowel Resection ◽  
Hospitalized Patients ◽  
Control Group ◽  
Technical Failure ◽  
Small Bowel Transit ◽  
Small Bowel Transit Time ◽  
Academic Center

Background. The inpatient status is a well-known risk factor for incomplete video capsule endoscopy (VCE) examinations due to prolonged transit time. We aimed to evaluate the effect of prucalopride on small bowel transit time for hospitalized patients undergoing VCE. Methods. We included all hospitalized patients who underwent VCE at a tertiary academic center from October 2011 through September 2016. A single 2 mg dose of prucalopride was given exclusively for all patients who underwent VCE between March 2014 and December 2015. VCE studies were excluded if the capsule was retained or endoscopically placed, if other prokinetic agents were given, in cases with technical failure, or if patients had prior gastric or small bowel resection. Results. 442 VCE were identified, of which 68 were performed in hospitalized patients. 54 inpatients were included, of which 29 consecutive patients received prucalopride. The prucalopride group had a significantly shorter small bowel transit time compared to the control group (92 versus 275.5, p<0.001). There was a trend for a higher completion rate in the prucalopride group (93.1% versus 76%, p=0.12). Conclusions. Our results suggest that the administration of prucalopride prior to VCE is a simple and effective intervention to decrease small bowel transit time.

Enhanced Diagnostic Yield with Increased Small Bowel Transit Time During Capsule Endoscopy

2008 ◽  
Vol 67 (5) ◽  
pp. AB258
Author(s):  
Jonathan M. Buscaglia ◽  
Sumit Kapoor ◽  
John O. Clarke ◽  
Priscilla Magno ◽  
Samuel A. Giday ◽  
...  
Keyword(s):  
Small Bowel ◽  
Transit Time ◽  
Capsule Endoscopy ◽  
Diagnostic Yield ◽  
Small Bowel Transit ◽  
Small Bowel Transit Time

scholarly journals Enhanced Diagnostic Yield with Prolonged Small Bowel Transit Time during Capsule Endoscopy

2008 ◽  
pp. 303-308 ◽  
Author(s):  
Jonathan M. Buscaglia ◽  
Sumit Kapoor ◽  
John O. Clarke ◽  
Juan Carlos Bucobo ◽  
Samuel A. Giday ◽  
...  
Keyword(s):  
Small Bowel ◽  
Transit Time ◽  
Capsule Endoscopy ◽  
Diagnostic Yield ◽  
Small Bowel Transit ◽  
Small Bowel Transit Time

scholarly journals Gastrointestinal Physiology Before and After Duodenal Switch with Comparisons to Unoperated Lean Controls: Novel Use of the SmartPill Wireless Motility Capsule

2021 ◽  
Author(s):  
Khalid Elias ◽  
Per M. Hellström ◽  
Dominic-Luc Webb ◽  
Magnus Sundbom
Keyword(s):  
Small Bowel ◽  
Transit Time ◽  
Duodenal Switch ◽  
Rating Scale ◽  
Gastrointestinal Symptoms ◽  
Small Bowel Transit ◽  
Gastrointestinal Physiology ◽  
Time Points ◽  
Small Bowel Transit Time ◽  
Wireless Motility Capsule

Abstract Purpose Bariatric surgery alters gastrointestinal anatomy. In this exploratory study, the SmartPill® wireless motility capsule (WMC) was used to study changes in gastrointestinal physiology following biliopancreatic diversion with duodenal switch (BPD/DS). Material and Methods Twenty-eight BPD/DS patients (35 ± 11 years, 50% females, body mass index [BMI] 56 ± 5) were to be examined preoperatively and postoperatively. In addition to transit time, appetite control and gastrointestinal symptoms were studied by patient-scored questionnaires (visual analogue scale and Gastrointestinal Symptom Rating Scale (GSRS)). Data was compared to 41 lean unoperated controls. Results About 1.8 years postoperatively, 18 patients (BMI 35.8 ± 8.3) returned for a second WMC test. As expected, small bowel transit time was reduced, from 3.9 ± 1.6 h to 2.8 ± 2.0, p = 0.02, and at both these time points, it was shorter than in lean controls (5.4 ± 1.9 h, p = 0.001). Postoperatively, a trend towards reduced colon and whole gut transit times was seen in BPD/DS-patients, thus approaching those of lean controls. Surprisingly, BPD/DS patients scored higher satiety than controls preoperatively as well as increased hunger and desire to eat postoperatively. Compared to lean, BPD/DS patients reported a higher total GSRS score at both time points (1.2 ± 0.2 vs 1.7 ± 0.6 and 2.3 ± 0.5, p < 0.001). Postoperatively, the scores for diarrhea and indigestion increased. Conclusions The novel use of the SmartPill system in BPD/DS patients gave the expected readouts. Although small bowel transit time was further shortened after BPD/DS, whole gut transit time did not differ from controls. Typical gastrointestinal symptoms were reported postoperatively. Graphical abstract

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