scholarly journals Serum Ferritin Is Associated with Metabolic Syndrome and Red Meat Consumption

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Avila Felipe ◽  
Echeverría Guadalupe ◽  
Pérez Druso ◽  
Martinez Carlos ◽  
Strobel Pablo ◽  
...  

Background and Aims. Hyperferritinemia has been related with a wide spectrum of pathologies, including diabetes, cardiovascular disease, neurodegenerative disorders, and metabolic syndrome. The aim of this study was to investigate the association between hyperferritinemia and iron consumption.Methods and Results. Serum ferritin concentration was evaluated in 66 presumed healthy men, along with other clinical and biochemical markers of chronic diseases. A three-day food questionnaire was applied for nutrition information. Hyperferritinemia was a condition found in 13.4% of the volunteers analyzed. Significant correlations were found between serum ferritin concentration and metabolic syndrome parameters (HDL cholesterol, triglycerides, and fasting glucose) as well as an increase of the serum ferritin mean value with the number of risk factors of metabolic syndrome. Also, oxidative stress markers (carbonyl groups, AOPP, and glycated hemoglobin), hepatic damage markers (GGT, SGOT), and parameters related to insulin resistance (HOMA, blood insulin, and blood glucose) correlate significantly with serum ferritin. Volunteers had an excessive iron intake, principally by bread consumption. Analyses of food intake showed that red meat consumption correlates significantly with serum ferritin.Conclusion. Red meat consumption, metabolic syndrome, and chronic disease markers are associated with hyperferritinemia in a population of Chilean men.

2019 ◽  
Vol 8 (2) ◽  
pp. 77-86
Author(s):  
Ahsan Mohammed Hafiz ◽  
Md Sumon Rana ◽  
KM Tarikul Islam ◽  
Milton Kumer Saha ◽  
Md Atikur Rahman ◽  
...  

Background: Stroke (ischaemic & haemorrhagic) is a major cause of mortality and morbidity in the developed as well as in the developing countries. Perihaematoma oedema and haematoma expansion are two important points to be considered when deciding outcome of patients with ICH. Brain damage due to haematoma may be irreversible but the injury from perihaematoma oedema may be reversible. It has been seen that S. ferritin is the most reliable indicator of body iron. Treatment with iron chelators may give better outcome after ICH. Objective: This study was under taken to assess the association between serum ferritin and relative perihaematoma oedema volume. Methodology: This study was a cross sectional observational study that was conducted in the Departments of Neurosurgery & Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Dhaka Medical College Hospital (DMCH) from 1st March, 2014 till 30th September, 2015 on 32 patients (32) who fulfilled the selection criteria were enrolled in this study. Results: In this study, male female ratio was 1:1 and the mean age was 56±15 years. Most of the ICH patients fell in the age group between 41-60 years (53%). During admission, grade-1 (GCS 3- 8) level of consciousness was reported among 45% of patients. All the patients in this study presented with motor deficit that include hemiplegia 20 (62.5%) and hemiparesis 12 (37.5%). Mean value of serum ferritin was found elevated on day 4 (344±406 μg/L) in comparison to day 1 (213.4±123.5μg/ L). Mean value of relative perihaematoma oedema was elevated on day 4 (4±2.7) than day 1 (1.9±1) but it was not statistically significant. Conclusion: In this study after statistical analysis by Pearson’s correlation test we found that there was no significant association between serum ferritin concentration and relative perihaematoma oedema on day-1 and day-4. Bang. J Neurosurgery 2019; 8(2): 77-86


BMJ ◽  
1983 ◽  
Vol 286 (6381) ◽  
pp. 1864-1864 ◽  
Author(s):  
M A Morgan ◽  
A V Hoffbrand ◽  
M Laulicht ◽  
W Luck ◽  
S Knowles

2021 ◽  
pp. 1-15
Author(s):  
Khemayanto Hidayat ◽  
Wan-Zhan Zhu ◽  
Si-Min Peng ◽  
Jin-Jin Ren ◽  
Meng-Lan Lu ◽  
...  

Abstract The findings regarding the associations between red meat, fish and poultry consumption, and the metabolic syndrome (Mets) have been inconclusive, and evidence from Chinese populations is scarce. A cross-sectional study was performed to investigate the associations between red meat, fish and poultry consumption, and the prevalence of the Mets and its components among the residents of Suzhou Industrial Park, Suzhou, China. A total of 4424 participants were eligible for the analysis. A logistic regression model was used to estimate the OR and 95 % CI for the prevalence of the Mets and its components according to red meat, fish and poultry consumption. In addition, the data of our cross-sectional study were meta-analysed under a random effects model along with those of published observational studies to generate the summary relative risks (RR) of the associations between the highest v. lowest categories of red meat, fish and poultry consumption and the Mets and its components. In the cross-sectional study, the multivariable-adjusted OR for the highest v. lowest quartiles of consumption was 1·23 (95 % CI 1·02, 1·48) for red meat, 0·83 (95 % CI 0·72, 0·97) for fish and 0·93 (95 % CI 0·74, 1·18) for poultry. In the meta-analysis, the pooled RR for the highest v. lowest categories of consumption was 1·20 (95 % CI 1·06, 1·35) for red meat, 0·88 (95 % CI 0·81, 0·96) for fish and 0·97 (95 % CI 0·85, 1·10) for poultry. The findings of both cross-sectional studies and meta-analyses indicated that the association between fish consumption and the Mets may be partly driven by the inverse association of fish consumption with elevated TAG and reduced HDL-cholesterol and, to a lesser extent, fasting plasma glucose. No clear pattern of associations was observed between red meat or poultry consumption and the components of the Mets. The current findings add weight to the evidence that the Mets may be positively associated with red meat consumption, inversely associated with fish consumption and neutrally associated with poultry consumption.


2013 ◽  
Vol 66 (5) ◽  
pp. 438-440 ◽  
Author(s):  
Martin A Crook ◽  
Patrick L C Walker

There are many causes of raised serum ferritin concentrations including iron overload, inflammation and liver disease to name but a few examples. Cases of extreme hyperferritinaemia (serum ferritin concentration equal to or greater than 10 000 ug/l) are being reported in laboratories but the causes of this are unclear. We conducted an audit study to explore this further. Extreme hyperferritinaemia was rare with only 0.08% of ferritin requests displaying this. The main causes of extreme hyperferritinaemia included multiple blood transfusions, malignant disease, hepatic disease and suspected Still's disease.


2001 ◽  
Vol 131 (1) ◽  
pp. 85-90 ◽  
Author(s):  
Siti Muslimatun ◽  
Marjanka K. Schmidt ◽  
Werner Schultink ◽  
Clive E. West ◽  
Joseph G.A.J. Hautvast ◽  
...  

1984 ◽  
Vol 17 (2) ◽  
pp. 85-91
Author(s):  
Koichi Hasegawa ◽  
Motoo Oda ◽  
Takeyuki Monna ◽  
Kiichiro Kikunami ◽  
Yoshiki Matsushita ◽  
...  

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