scholarly journals Recent Research Trends and Future Prospects in Nanozymes

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Ho Yun Shin ◽  
Tae Jung Park ◽  
Moon Il Kim
Keyword(s):  
Small Molecules ◽  
Low Cost ◽  
Scale Up ◽  
Cancer Diagnostics ◽  
Research Trends ◽  
Environmental Engineering ◽  
Future Prospects ◽  
Treatment Methods ◽  
Natural Enzyme ◽  
Enzyme Mimetics

Recently, nanomaterial-based enzyme mimetics (nanozymes) have attracted enormous interest. They exhibit unique advantages such as excellent robustness, stability, and low-cost production with easy scale-up, which are critically needed as an alternative to natural enzymes. These nanozymes exhibit natural enzyme-like activity and have been applied to various kinds of detection and treatment methods for biomolecules such as DNA, proteins, cells, and small molecules including glucose. To highlight progress in the field of nanozymes, this review discusses recent nanozyme-based research results and their applications for the development of novel biosensor, immunoassay, cancer diagnostics, therapeutics, and environmental engineering technologies. Current challenges and future prospects of nanozymes for widespread use in biotechnology are also discussed.

Constructive Optimisation of the Propeller Type Mixing Devices Using the Virtual and Rapid Prototyping

2017 ◽  
Vol 68 (3) ◽  
pp. 453-458 ◽  
Author(s):  
Daniel Besnea ◽  
Alina Spanu ◽  
Iuliana Marlena Prodea ◽  
Gheorghita Tomescu ◽  
Iolanda Constanta Panait
Keyword(s):  
Rapid Prototyping ◽  
Low Cost ◽  
Scale Up ◽  
Three Dimensional ◽  
Rapid Identification ◽  
Multidisciplinary Optimization ◽  
External Diameter ◽  
Process Industries ◽  
Parametric Cad ◽  
Shaft Torque

The paper points out the advantages of rapid prototyping for improving the performances/constructive optimization of mixing devices used in process industries, here exemplified to propeller types ones. The multidisciplinary optimization of the propeller profile affords its design using parametric CAD methods. Starting from the mathematical curve equations proposed for the blade profile, it was determined its three-dimensional virtual model. The challenge has been focused on the variation of propeller pitch and external diameter. Three dimensional ranges were manufactured using the additive manufacturing process with Marker Boot 3D printer. The mixing performances were tested on the mixing equipment measuring the minimum rotational speed and the correspondent shaft torque for complete suspension achieved for each of the three models. The virtual and rapid prototyping method is newly proposed by the authors to obtain the basic data for scale up of the mixing systems, in the case of flexible production (of low quantities), in which both the nature and concentration of the constituents in the final product varies often. It is an efficient and low cost method for the rapid identification of the optimal mixing device configuration, which contributes to the costs reduction and to the growing of the output.

scholarly journals Carbon nanomaterial hybrids via laser writing for high-performance non-enzymatic electrochemical sensors: a critical review

2021 ◽  
Author(s):  
Marcel Simsek ◽  
Nongnoot Wongkaew
Keyword(s):  
Noble Metal ◽  
Critical Review ◽  
High Performance ◽  
Carbon Nanomaterials ◽  
Electrochemical Sensors ◽  
Low Cost ◽  
Three Dimensional ◽  
Laser Writing ◽  
Enzyme Mimicking ◽  
Natural Enzyme

AbstractNon-enzymatic electrochemical sensors possess superior stability and affordability in comparison to natural enzyme-based counterparts. A large variety of nanomaterials have been introduced as enzyme mimicking with appreciable sensitivity and detection limit for various analytes of which glucose and H2O2 have been mostly investigated. The nanomaterials made from noble metal, non-noble metal, and metal composites, as well as carbon and their derivatives in various architectures, have been extensively proposed over the past years. Three-dimensional (3D) transducers especially realized from the hybrids of carbon nanomaterials either with metal-based nanocatalysts or heteroatom dopants are favorable owing to low cost, good electrical conductivity, and stability. In this critical review, we evaluate the current strategies to create such nanomaterials to serve as non-enzymatic transducers. Laser writing has emerged as a powerful tool for the next generation of devices owing to their low cost and resultant remarkable performance that are highly attractive to non-enzymatic transducers. So far, only few works have been reported, but in the coming years, more and more research on this topic is foreseeable. Graphical abstract

scholarly journals Recent Findings in Azaphilone Pigments

2021 ◽  
Vol 7 (7) ◽  
pp. 541
Author(s):  
Lúcia P. S. Pimenta ◽  
Dhionne C. Gomes ◽  
Patrícia G. Cardoso ◽  
Jacqueline A. Takahashi
Keyword(s):  
Water Solubility ◽  
Biological Activities ◽  
Low Cost ◽  
Scale Up ◽  
Structural Diversity ◽  
Downstream Processing ◽  
Global Market ◽  
Yield Improvement ◽  
Potential Applications ◽  
New Compounds

Filamentous fungi are known to biosynthesize an extraordinary range of azaphilones pigments with structural diversity and advantages over vegetal-derived colored natural products such agile and simple cultivation in the lab, acceptance of low-cost substrates, speed yield improvement, and ease of downstream processing. Modern genetic engineering allows industrial production, providing pigments with higher thermostability, water-solubility, and promising bioactivities combined with ecological functions. This review, covering the literature from 2020 onwards, focuses on the state-of-the-art of azaphilone dyes, the global market scenario, new compounds isolated in the period with respective biological activities, and biosynthetic pathways. Furthermore, we discussed the innovations of azaphilone cultivation and extraction techniques, as well as in yield improvement and scale-up. Potential applications in the food, cosmetic, pharmaceutical, and textile industries were also explored.

Point-of-entry adsorbers for the removal of fumigants

1995 ◽  
Vol 22 (1) ◽  
pp. 106-120
Author(s):  
Roberto M. Narbaitz ◽  
Frances Z. Parsons ◽  
Tsong-Yih Tzeng
Keyword(s):  
Organic Matter ◽  
Activated Carbon ◽  
Low Cost ◽  
Scale Up ◽  
Extensive Literature ◽  
Limited Data ◽  
Ethylene Dibromide ◽  
Point Of Entry ◽  
Naturally Occurring ◽  
Adsorption Data

Point-of-entry systems with granular activated carbon filters have been used extensively to provide safe water to rural homes with wells contaminated with synthetic organic chemicals. Because of the low cost of these systems, their design is generally based on the equilibrium column model, the isotherm data from the literature, and a scale-up factor. This paper analyzes the necessary scale-up factors for point-of-entry adsorbers based on fumigant adsorption data gathered through an extensive literature review. The fumigants evaluated are 1,2-dichloropropane, 1,2-dibromo-3-chloropropane, and ethylene dibromide. It was impossible to thoroughly assess the scale-up factors for 1,2-dichloropropane because of the limited data. Column data for the other two fumigants were sufficient to generate column loading lines, which can be used directly without resorting to scale-up factors. Column data showed that the scale-up factors are greatly affected by competitive adsorption with the naturally occurring background organic matter and by preloading of these organic matter. As these phenomena are not well understood, it is presently impossible to accurately predict the appropriate scale-up factors. A recommended design approach is outlined. Key words: adsorption, activated carbon, fumigants, point-of-entry.

scholarly journals Treatment of Combined Acid Black 48 and Coffee Wastewater by Low-Cost Adsorbents

2020 ◽  
Vol 76 (3) ◽  
pp. 47-61
Author(s):  
Yung-Tse Hung ◽  
Abhiram Pamula ◽  
Howard Paul
Keyword(s):  
Activated Carbon ◽  
Organic Carbon ◽  
Binary Mixture ◽  
Surface Waters ◽  
Low Cost ◽  
Combined Treatment ◽  
Synthetic Dyes ◽  
Treatment Methods ◽  
Onion Peel ◽  
Peanut Hull

Removal of synthetic dyes from wastewater is essential both from the environmental and human health point of view. A small concentration of synthetic dyes can reduce water transparency and consequently influence photosynthesis and alter aquatic ecosystems. Acid black 48 is an Azo dye that falls under the category of synthetic dyes used in the textile industry. With dyes, coffee wastewater has high chemical oxygen demand (COD) that can affect dissolved oxygen (DO) in surface waters. A mixture of wastes in surface waters creates a need to investigate the efficiency of existing treatment methods and optimize them. Adsorption using activated carbon is a conventional method used to remove dyes and heavy metals from wastewater. Industries prefer efficient and economical treatment methods to meet challenging effluent standards regarding COD, BOD, and intensity of color. The adsorption process was optimized using low-cost adsorbents in the current study, including peanut hull and onion peel, to treat a binary mixture of acid black 48 and coffee wastewater. After adsorption, microfiltration was used to remove any suspended solids from the wastewater solution. The performance of combined treatment processes for the color removal of the binary mixture was analyzed and compared using transmittance and absorbance. Treatment efficiency of adsorption using low-cost adsorbents was compared with powdered activated carbon. Apart from absorbance and transmittance, non-purgeable organic carbon (NPOC) values were analyzed to determine organic carbon removal in the combined binary wastewater. Experimental results indicated that Langmuir isotherm was the best fit for a binary mixture with an optimum dosage of 1.2 g using onion peel. The regression coefficient value was 0.82, and the uptake was 58.13 mg of binary mixture per 1 g of onion peel. The effective pH for maximum uptake of acid black 48 using onion peel for adsorption was 5.7. The increasing dosage of low-cost adsorbents adsorption improved in removing binary waste of dyes and coffee waste from wastewater. Adsorption using onion peel improved adsorbent performance up to 1.2 g dosage and steadily decreased beyond that. The adsorption capacity of onion peel was comparatively higher than the peanut hull based on the linear fit.

scholarly journals Influence of inlet air distributor geometry on the fluid dynamics of conical spouted beds: A CFD study

2018 ◽  
Vol 24 (4) ◽  
pp. 369-378 ◽  
Author(s):  
J.N.M. Batista ◽  
R.C. Brito ◽  
R. Béttega
Keyword(s):  
Fluid Dynamics ◽  
Cfd Simulation ◽  
Low Cost ◽  
Scale Up ◽  
Straight Tube ◽  
Spouted Bed ◽  
Bed Height ◽  
Spouted Beds ◽  
Wide Range ◽  
Solid Dynamics

The spouted bed presents limitations in terms of scale-up. Furthermore, its stability depends on its geometry as well as the properties of the fluid and solid phases. CFD provides an important tool to improve understanding of these aspects, enabling a wide range of information to be obtained rapidly and at low cost. In this work, CFD simulation was used to evaluate the effects of different inlet air distributors (Venturi and straight tube) and the effects of static bed height on the fluid and solid dynamics of a conical spouted bed. Simulations were performed using the two-dimensional Euler-Euler approach. In order to evaluate the fluid dynamics model, static pressure data obtained by simulation were compared with experimental data obtained with the Venturi distributor. The fluid and solid dynamics of the conical spouted bed were obtained by CFD simulation. The results showed that the pressure drop was lower for the straight tube air distributor, while the Venturi air distributor provided higher stability and a more homogenous air distribution at the bed entrance.

scholarly journals Educational And Financial Impact Of Technology On Workforce Development

2013 ◽  
Vol 6 (5) ◽  
pp. 513-520 ◽  
Author(s):  
Paul J. Carruth ◽  
Ann K. Carruth
Keyword(s):  
Online Education ◽  
Organizational Performance ◽  
Workforce Development ◽  
Research Trends ◽  
Financial Impact ◽  
Work Place ◽  
Future Prospects ◽  
The Past ◽  
E Learning ◽  
Impact Of Technology

In the current evolving economic environment, developing and implementing an effective workforce to improve the skills and capability of employees are seen as central to improving individual and organizational performance and competitiveness. The availability of online education in universities as well as the work place has significantly increased during the past decade. This paper summarizes and addresses the current research, trends and future prospects of e-learning as it relates to the awarding of higher educational degrees and private sector workforce development.

scholarly journals A credible pathway for heavy ion driven target fabrication and injection

2002 ◽  
Vol 20 (3) ◽  
pp. 515-520 ◽  
Author(s):  
D.T. GOODIN ◽  
A. NOBILE ◽  
N.B. ALEXANDER ◽  
L.C. BROWN ◽  
J.L. MAXWELL ◽  
...  
Keyword(s):  
Low Cost ◽  
Fusion Energy ◽  
Scale Up ◽  
Development Program ◽  
High Volume ◽  
Heavy Ion ◽  
Current Status ◽  
Target Chamber ◽  
Inertial Fusion ◽  
Inertial Fusion Energy

The Target Fabrication Facility (TFF) of an inertial fusion energy (IFE) power plant must supply about 500,000 targets per day. The target is injected into the target chamber at a rate of 5–10 Hz and tracked precisely so the heavy ion driver beams can be directed to the target. The feasibility of developing successful fabrication and injection methodologies at the low cost required for energy production (about $0.25/target, approximately 104 times less than current costs) is a critical issue for inertial fusion energy. A significant program is underway to develop the high-volume methods to supply economical IFE targets. This article reviews the requirements for heavy ion driven IFE target fabrication and injection, and presents the current status of and results from the development program. For the first time, an entire pathway from beginning to end is outlined for fabrication of a high-gain, distributed radiator target. A significant development and scale-up program will be necessary to implement this pathway for mass production of IFE targets.

scholarly journals Basic Materials Studies of Lanthanide Halide Scintillators

2007 ◽  
Vol 1038 ◽  
Author(s):  
F. P. Doty ◽  
Douglas McGregor ◽  
Mark Harrison ◽  
Kip Findley ◽  
Raulf Polichar ◽  
...  
Keyword(s):  
Gamma Ray ◽  
Materials Science ◽  
Low Cost ◽  
Large Diameter ◽  
Scale Up ◽  
Chemical Properties ◽  
Anisotropic Plasticity ◽  
Ongoing Work ◽  
Perfect Cleavage ◽  
Physical And Chemical

AbstractCerium and lanthanum tribromides and trichlorides form isomorphous alloys with the hexagonal UCl3 type structure, and have been shown to exhibit high luminosity and proportional response, making them attractive alternatives for room temperature gamma ray spectroscopy. However the fundamental physical and chemical properties of this system introduce challenges for material processing, scale-up, and detector fabrication. In particular, low fracture stress and perfect cleavage along prismatic planes cause profuse cracking during and after crystal growth, impeding efforts to scale this system for production of low cost, large diameter spectrometers. We have reported progress on basic materials science of the lanthanide halides. Studies to date have included thermomechanical and thermogravimetric analyses, hygroscopicity, yield strength, and fracture toughness. The observed mechanical properties pose challenging problems for material production and post processing; therefore, understanding mechanical behavior is key to fabricating large single crystals, and engineering of robust detectors and systems. Analysis of the symmetry and crystal structure of this system, including identification of densely-packed and electrically neutral planes with slip and cleavage, and comparison of relative formation and propagation energies for proposed slip systems, suggest possible mechanisms for deformation and crack initiation under stress. The low c/a ratio and low symmetry relative to traditional scintillators indicate limited and highly anisotropic plasticity cause redistribution of residual process stress to cleavage planes, initiating fracture. Ongoing work to develop fracture resistant lanthanide halides is presented.

Image Processing for Solar Cell Analysis, Diagnostics and Quality Assurance Inspection

2013 ◽  
pp. 338-375
Author(s):  
Michael G. Mauk
Keyword(s):  
Image Processing ◽  
Image Analysis ◽  
Quality Assurance ◽  
Solar Cell ◽  
Process Development ◽  
Low Cost ◽  
Scale Up ◽  
Image Capturing ◽  
Infrared Cameras ◽  
Primary Focus

Image capturing, processing, and analysis have numerous uses in solar cell research, device and process development and characterization, process control, and quality assurance and inspection. Solar cell image processing is expanding due to the increasing performance (resolution, sensitivity, spectral range) and low-cost of commercial CCD and infrared cameras. Methods and applications are discussed, with primary focus on monocrystalline and polycrystalline silicon solar cells using visible and infrared (thermography) wavelengths. The most prominent applications relate to mapping of minority carrier lifetime, shunts, and defects in solar cell wafers, in various stages of the manufacturing process. Other applications include measurements of surface texture and reflectivity, surface cleanliness, integrity of metallization lines, uniformity of coatings, and crystallographic texture and grain size. Image processing offers the capability to assess large-areas (> 100 cm2) with a non-contact, fast (~ 1 second), and modest cost. The challenge is to quantify and interpret the image data in order to better inform device design, process engineering, and quality control. Many promising solar cell technologies fail in the transition from laboratory to factory due to issues related to scale-up in area and manufacturing throughput. Image analysis provides an effective method to assess areal uniformity, device-to-device reproducibility, and defect densities. More integration of image analysis from research devices to field testing of modules will continue as the photovoltaics industry matures.

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