scholarly journals Optical Coherence Tomography in Patients with Chiari I Malformation

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Michele Figus ◽  
Chiara Posarelli ◽  
Francesco Nasini ◽  
Paolo Perrini ◽  
Mario Miccoli ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Chiari I Malformation ◽  
Nerve Fibers ◽  
Healthy Controls ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Chiari I

Background/Aims. To evaluate optic nerve head with spectral domain optical coherence tomography (OCT) in patients with Chiari I malformation (CMI) compared to healthy controls.Methods. Cross-sectional study. OCT of the optic nerve head of 22 patients with CMI and 22 healthy controls was quantitatively analyzed. The healthy controls were matched for age and sex with the study population. Mean retinal nerve fiber layer (RNFL) thickness was calculated for both eyes; the mean thickness value was also registered for each quadrant and for each subfield of the four quadrants.Results. CMI patients showed a reduction of the RNFL thickness in both eyes. This reduction was more statistically significant (P<0.05) for the inferior quadrant in the right eye and in each quadrant than nasal one in the left eye.Conclusion. A distress of the retinal nerve fibers could explain the observed reduction of the RNFL thickness in patients with CMI; in our series the reduction of the RNFL thickness seems lower when CMI is associated with syringomyelia.

scholarly journals Polarization-sensitive optical coherence tomography as a tool to visualize the fiber direction of retinal nerves and peripapillary sclera

2020 ◽  
Vol 238 ◽  
pp. 04003
Author(s):  
Joy Willemse ◽  
Frank Verbraak ◽  
Johannes de Boer
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Healthy Volunteers ◽  
Optic Nerve Head ◽  
Nerve Fibers ◽  
Optic Axis ◽  
Fiber Direction ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Axis Orientation

Polarization sensitive optical coherence tomography (PS-OCT) has been used to visualize the orientation of the nerves in the retinal nerve fiber layer (RNFL) and to visualize the orientation of the collagen fibers in peripapillary sclera in retinas of healthy volunteers. Optic axis orientation images clearly visualize the nerve fibers leaving the optic nerve head (ONH) in all radial directions. Sclera orientation images show that the sclera consist of two layers, an inner layer with an orientation parallel to the RNFL orientation, and a deeper layer where the collagen is circularly oriented.

Synchronous evaluation of early neurovascular changes in macula and optic nerve head in early diabetic retinopathy using combined optical coherence tomography angiography parameters

2019 ◽  
Author(s):  
Xin Wen ◽  
Zijing Li ◽  
Jiaqi Liang ◽  
Jianhui Xiao ◽  
Yichi Zhang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence Tomography Angiography ◽  
Diabetic Patients ◽  
Healthy Controls ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Type 2 Diabetic Patients

Abstract Background This study aim to evaluate neurovascular changes in both macula and optic nerve head (ONH) in early stages of diabetic retinopathy (DR) using combined quantitative optical coherence tomography angiography (OCTA) parameters.Methods We studied 194 right eyes from 64 type 2 diabetic patients without DR (DM), 64 diabetic patients with nonproliferative diabetic retinopathy (NPDR) and 64 age-matched healthy controls. OCTA parameters were analyzed using binary logistic regression models and receiver operating characteristic (ROC) curves.Results There was significant reduction of vessel density (VD) in both macula and ONH comparing DM patients with and without NPDR to controls. The area under the curve (AUC) of the ROC curve for NPDR versus control was 0.963 ( p <0.001), with sensitivity of 93.8% and specificity of 90.6%. The ROC curves for NPDR patients versus NoDR patients (including DM and control groups) exhibited an AUC of 0.923 ( p <0.001), with sensitivity of 90.6% and specificity of 82.8%. The thickness of the retinal nerve fiber layer (RNFL) in both macula and ONH was not significantly different among these three groups.Conclusions VD in both macula and ONH was simultaneously decreased prior to RNFL thinning in DM patients through the course proceeding from preclinical DR to NPDR. Combined analysis of macula and ONH parameters was an comprehensive and accurate OCTA metric to distinguish NPDR patients from healthy controls and DM patients without DR.

Assessment of optic nerve head parameters using optical coherence tomography angiography in behçet uveitis patients with healthy controls

2020 ◽  
Vol 29 (2) ◽  
pp. 131
Author(s):  
Melike BALIKOGLU ◽  
Erdinc AYDIN ◽  
Pinar NALCACIOGLU ◽  
Nur DOGANAY KUMCU ◽  
Seher SARITEPE IMREL ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Optical Coherence Tomography Angiography ◽  
Healthy Controls ◽  
Optical Coherence

Precision of Optic Nerve Head and Retinal Nerve Fiber Layer Parameter Measurements by Spectral-domain Optical Coherence Tomography

2018 ◽  
Vol 27 (5) ◽  
pp. 407-414 ◽  
Author(s):  
Laura M. Schrems-Hoesl ◽  
Wolfgang A. Schrems ◽  
Robert Laemmer ◽  
Friedrich E. Kruse ◽  
Christian Y. Mardin
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Optic Nerve Head ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Layer Parameter

scholarly journals Evaluation of the optic nerve head vessel density in patients with limited scleroderma

2021 ◽  
Vol 13 ◽  
pp. 251584142199538
Author(s):  
Hilal Kılınç Hekimsoy ◽  
Ali Mehmet Şekeroğlu ◽  
Ali Mert Koçer ◽  
Vedat Hekimsoy ◽  
Ali Akdoğan
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Vessel Density ◽  
Optical Coherence ◽  
Control Subjects ◽  
Rnfl Thickness ◽  
Significant Difference ◽  
Healthy Control ◽  
Limited Scleroderma

Objectives: To investigate the optical coherence tomography angiography (OCTA) parameters of the optic nerve head and peripapillary retina and to assess macular and peripapillary retinal nerve fiber layer (RNFL) thickness by using spectral-domain optical coherence tomography (SD-OCT) in patients with limited scleroderma and to compare these results with those of healthy control subjects. Materials and Methods: 42 patients with a confirmed diagnosis of limited scleroderma and 32 age- and sex-matched healthy control subjects were included in the study. OCTA was performed for the radial peripapillary capillary plexus (RPCP) whole image, inside disc, and peripapillary vessel densities in all participants with XR Avanti AngioVue OCTA (Optovue, Fremont, California, USA). OCT images were obtained with Spectralis OCT with eye-tracking dual-beam technology (Heidelberg Engineering GmbH, Heidelberg, Germany), and peripapillary RNFL thickness was evaluated with circle program. The data from the right eyes of all participants were used for statistical analysis. Results: No significant difference was found between the radial RPCP whole image, inside disc, and peripapillary vessel density values or the RNFL parameters of the scleroderma patients when compared with the controls ( p > 0.05 for all). Conclusion: Decreased peripapillary vessel density on OCTA, which can be an early sign of glaucoma, could not be observed in scleroderma patients in this study. However, further long-term studies are still needed to identify glaucoma tendency in patients with scleroderma before clinically detectable glaucoma.

scholarly journals Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

2019 ◽  
Vol 23 (1) ◽  
pp. 97-112 ◽  
Author(s):  
Kathleen L. Graham ◽  
Christina I. McCowan ◽  
Kelly Caruso ◽  
F. Mark Billson ◽  
Cameron J. G. Whittaker ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Nerve Fiber ◽  
Optic Nerve Head ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer

scholarly journals Retinal Nerve Fiber Layer Assessment Using Optical Coherence Tomography with Active Optic Nerve Head Tracking

2006 ◽  
Vol 47 (3) ◽  
pp. 964 ◽  
Author(s):  
Hiroshi Ishikawa ◽  
Michelle L. Gabriele ◽  
Gadi Wollstein ◽  
R. Daniel Ferguson ◽  
Daniel X. Hammer ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Optic Nerve Head ◽  
Head Tracking ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Retinal Nerve Fiber
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