scholarly journals Oral Lesions: The Clue to Diagnosis of Pemphigus Vulgaris

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Diana Kuriachan ◽  
Rakesh Suresh ◽  
Mahija Janardhanan ◽  
Vindhya Savithri

Pemphigus is a group of potentially fatal dermatoses with both cutaneous and oral manifestations. Characterized by the appearance of vesicle or bullae, their manifestations in the oral cavity often precede those on the skin by many months or may remain as the only symptoms of the disease. It is therefore important that the oral manifestations of the disease are recognized on time, to make a proper diagnosis and initiate timely treatment. Here we present a case of Pemphigus Vulgaris (PV) that presented with oral lesions at multiple sites including tongue, to highlight the importance of timely recognition of the oral lesions during routine dental practice for the diagnosis and management of this disease.

2018 ◽  
Vol 2 (2) ◽  
pp. 117-124
Author(s):  
Indra Gunawan ◽  
Riani Setiadhi

Background : Pemphigus Vulgaris (PV) is an autoimmune intraepithelial blistering disease involving the skin and mucous membranes. Oral lesions could be the first sign of the disease followed by the involvement of skin and other mucosa sites.Objectives : This is oral manifestations of pemphigus vulgaris case report, intended to help clinicians to recognize and treat the oral lesions.Case Reported : Male 27 yo admitted to RSUP Dr.Hasan Sadikin hospital with multiple blisters on the skin and oral mucosa, was diagnosed with Pemphigus Vulgaris.Case Management : Patient was treated with steroid mouth wash and oral paste. After two months of treatment, the patient was fully recovered from oral lesion.Discussion : In PV, autoantibodies are produced against desmosomes spesifically desmoglein 3 which responsible for holding the cells of the epithelium together. The loss of adhesive function due to anti Dsg 3 antibodies result in bulla formation on the oral mucosa.The aetiology for PV is still uncertain. Conclusion :Early recognition and treatment of oral lesions is important as it may prevent skin involvement. Early treatment, patient’s compliance and multi disciplinal teamwork ensure the treatment succes for this disease


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 969
Author(s):  
Hager Moustafa Saeed ◽  
Eman Mohammad Amr ◽  
Alshaimaa Rezk Lotfy Rezk ◽  
Wesam Abd Elmoneim

Background: Several systemic diseases manifest themselves in the oral cavity. Oral manifestations of lupus erythematosus (LE) are associated with a significantly increased risk of cancer. Dentists who are unaware of these lesions will possibly miss them. This cross-sectional study aimed to assess the prevalence of oral manifestations in patients with LE in a sample of the Egyptian population. Methods: A descriptive study was performed on 189 patients attending the Internal Medicine Department, Rheumatology Clinic in EL Qasr EL Ainy Hospital, Cairo University. Every patient was examined clinically after completing a questionnaire. Moreover, patients’ medical records were also evaluated.  The oral manifestations were recorded according to the WHO guide to physical examination of the oral cavity and classified according to their morphologic aspects and localization. Results: Out of 189 patients, there were 182 females (96.3%) and seven males (3.7%). The prevalence of oral lesions in LE patients was 55.6%. The most affected site was the tongue 25.7%. The most common clinical aspect was patches, 53%. About 77.1% of the lesions were asymptomatic. 74.3% of the patients had oral candidiasis. The prevalence of skin lesions in LE patients was 37.6%. The most common finding was malar rash 79%. Conclusions: The present study emphasizes the importance of early diagnosis of oral lesions to recognize patients with LE as the WHO considers oral manifestations of LE a widespread state associated with an increased risk of cancer. Also, implementation of oral hygiene measures and treatment to improve patients’ nutritional state and health-related quality of life are recommended.


2004 ◽  
Vol 51 (2) ◽  
pp. 103-106
Author(s):  
Ljiljana Markovic ◽  
Besir Ljuskovic

Crohn's disease is a chronic granulomatous inflammatory bowel disease of unknown cause. Segments of the whole gastrointestinal tract may be involved, including the oral cavity. The most common oral manifestations of Crohn's disease are edema, ulcerative and hyperplastic lesions. They appear most commonly on the lips, gingival tissue and buccal mucosa. Oral manifestations of Crohn's disease may precede intestinal symptoms. Recognition of these oral manifestations may lead to quicker diagnosis and earlier adequate treatment. If Crohn's disease is diagnosed, the dentist must make a detailed oral cavity examination and implement treatment of the existing oral lesions. Also, the dentist must provide prevention against caries and periodontal disease in these patients. Considering the frequency of oral manifestations of Crohn's disease, cooperation between gastroenterologist and dentist is very important.


Author(s):  
Santosh Kumar Swain ◽  
Priyanka Debta ◽  
Ansuman Sahu ◽  
Smarita Lenka

<p class="abstract">Coronavirus disease 2019 (COVID-19) is a threat to the global health caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The lungs are the primary site of infection in COVID-19 patient and the symptoms ranges from mild flu like manifestations to fulminant pneumonia and respiratory failure. COVID-19 infection also significantly affects the oral cavity and salivary glands with oral mucosal manifestations. Other than airway manifestations, COVID-19 patients are presenting with oral cavity lesions such as aphthous like ulcers, glossitis, oral mucositis or stomatitis, oral candidiasis and herpetic recurrences. These oral lesions are often associated with immunocompromised patients and elderly age. Direct involvement of the SARS-CoV-2 virus for development of oral ulcers remains uncertain. The salivary gland related symptoms and taste disturbances are highly common in COVID-19 patients. In COVID-19 patient, certain presentations like ulcers or blisters or diffuse reddish lesions affect both keratinized and non-keratinized tissues of the oral cavity. These lesions are found in palate, lip mucosa, buccal mucosa and tongue. The ulceration and blisters of the oral cavity are more often seen. There is still a gap of knowledge related to the oral manifestations of the COVID-19 infections and its impact on the oral cavity. This review article discussed the details of the oral cavity lesions in COVID-19 patients.</p>


Author(s):  
Lasya Mandadi ◽  
N. Rajendran ◽  
P. Shakthi ◽  
Vandana S.

<p class="abstract"><strong>Background:</strong> Oral mucosa reflects the general health of an individual. In certain systemic diseases oral cavity may be affected first or it could the only clue to diagnosis. Hence skin examination is never complete without the examination of mucosae. Aims and objectives were to find out the frequency and diversity of oral mucosal lesions in patients attending Dermatology, Venereology and Leprosy (DVL) outpatient department (OPD).</p><p class="abstract"><strong>Methods:</strong> This was a hospital based observational study. All patients with oral mucosal lesions fulfilling the inclusion &amp;exclusion criteria were enrolled in the study. Detailed history, physical examination and clinical photographs were recorded for all the patients.<strong></strong></p><p class="abstract"><strong>Results:</strong> The prevalence oral mucosal lesions among dermatological patients is 1.04% with a female predilection and the mean age was 38.44±17.30. Majority of the patients belonged to the age group of 31-60 years. Established risk factors for developing oral lesions like tobacco and beetle nut use was found in only 24% and 16% of the patients respectively. Twenty% (21%) of the patients were diabetic and the commonest oral lesions in them was oral candidiasis. Eighteen% (18%) of the patients presented with only oral complaints, while 82% of patients came with skin complaints and their oral lesions were incidental findings. Out of 82 patients with dermatological diseases specific mucocutaneous diseases were seen in 44% of patients. Most common dermatological diseases seen were vitiligo, lichen planus and pemphigus vulgaris.</p><p class="abstract"><strong>Conclusions:</strong> Knowing the prevalence of oral lesions as a part of mucocutaneous disorders would help sensitise other specialities the need to examine oral cavity in order to attain appropriate and early diagnosis.</p>


2016 ◽  
Vol 5 (01) ◽  
pp. 4764
Author(s):  
Anil Kumar Singh ◽  
Ram Krushna Panda ◽  
Shriram Chandra Mishra ◽  
Manish Singh ◽  
Akhil N. Parida

Psychosomatic - psyche (mind) and soma (body) -A psychosomatic disorder is a disease which involves both mind and body. Some physical diseases are thought to be particularly prone to be made worse by mental conditions such as stress and anxiety. Your current mental status can influence how bad a physical disease is, at any given time. Both mind and body are a single identity, so the involvements of one definitely affect the others. So the bidirectional approach should be done to proper diagnosis and management of psychosomatic disorders. In Ayurveda detail description is given about psychic (Manasika), Somatic (Sharirika) and psychosomatic disorders (Manodaihika Vyadhi), their mode of treatment, they are as follows.


2021 ◽  
Vol 2 (12(81)) ◽  
pp. 39-43
Author(s):  
M. Ibragimov ◽  
Y. Heydarova ◽  
A. Alizade ◽  
L. Ibragimova

This scientific article discusses the oral manifestations of diseases of the gastrointestinal tract. This problem is relevant both for dentists and family doctors. In medicine, for a long period of time, the relationship between diseases affecting the gastrointestinal tract and their symptoms manifested in the oral cavity has been considered. Many scientists and physicians have dealt with this problem, their several opinions are presented in this article. There is a hypothesis among researchers that the oral cavity is a mirror in which all human diseases can be visible. In the oral cavity, most of the alterations occurring in the organism are manifested, due to which, with an attentive attitude to oral manifestations, the disease can be detected already at the initial stage.


1989 ◽  
Vol 18 (1) ◽  
pp. 49-53 ◽  
Author(s):  
G. Laskaris ◽  
A. Sklavounou ◽  
A. Stavrou ◽  
K. Stavropoulou

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