scholarly journals Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Masanari Watanabe ◽  
Hisashi Noma ◽  
Jun Kurai ◽  
Hiroyuki Sano ◽  
Rumiko Saito ◽  
...  

The objective of the study was to investigate the influence of Asian dust storms (ADS) on pulmonary function of school children and the relationship of this effect with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children from April to May 2012 and in 384 of these children from March to May 2013. The data were analyzed for an association between ADS events and PEF by linear mixed models. Interleukin-8 transcriptional activity was assessed in THP-G8 cells stimulated by airborne particles collected on ADS days. Seven ADS days were identified: April 23 and 24, 2012; March 8 to 10, 2013; and March 19 and 20, 2013. Changes in PEF after ADS exposure were −8.17 L/min (95% confidence interval, −11.40 to −4.93) in 2012 and −1.17 L/min (−4.07 to 1.74) in 2013, and there was a significant difference between 2012 and 2013. Interleukin-8 transcriptional activity was significantly higher in 2012 at10.6±2.9-fold compared to3.7±0.4in March 8 to 10, 2013, and2.3±0.2in March 19 and 20, 2013. The influence of ADS events on pulmonary function of children differs with each ADS event and may be related to interleukin-8 production.

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Ling Hu ◽  
Wanqun Chen ◽  
Ming Cheng ◽  
Ting Zhang ◽  
Shaoyang Lan ◽  
...  

To investigate the relationship of MUC1, MUC5AC, and the syndrome of spleen and stomach, 109 subjects (34 peptic ulcer (PU), 62 chronic gastritis (CG), and 13 healthy volunteers (CON)) were included. All the subjects included were surveyed with questionnaire to classify them into damp-heat syndrome of spleen and stomach (DHSS), spleen-qi deficiency syndrome (SQD), and CON, examined by gastric endoscope, and biopsied. Rapid urease and methylene blue staining (MBS) were performed on every subject to diagnose for Helicobacter pylori (Hp) infection, and both were defined as Hp-positive. Hematoxylin and eosin (HE) staining was performed on every specimen to explore the histomorphology, inflammatory degree, and inflammatory activity of different groups; then Elivision™ plus kit was used to test the expression of MUC1 and MUC5AC. All the results of digital images were reviewed by two experts blindly. The inflammatory degree with Hp infection was higher than those uninfected or CON, but no significant difference was found between DHSS and SQD. And the expressions of MUC5AC with positive Hp was higher than those with negative Hp or CON regardless of the deficiency and solid syndrome of spleen-stomach but not for MUC1. We speculate that the deficiency and solid syndrome of spleen-stomach is a condition like Tai Ji symbol of dynamic equilibrium, showing the higher expression of MUC5AC but no change of MUC1 in the circumstance of Hp infection.


2017 ◽  
Vol 9 (1) ◽  
pp. 51-56 ◽  
Author(s):  
Adebisi I. Hammed ◽  
Elvis I. Agbonlahor

Summary Study aim: Was to investigate the relationship of anthropometrics with handgrip strength (HGS) among Nigerian school children.Material and methods: A total of 200 school children participated in this study. An electronic handgrip dynamometer was used to measure handgrip strength (HGS) in kg. Body height and body weight were measured with a wall-mounted stadiometer in meters and a bathroom weighing scale in kg, respectively. Body mass index (BMI) was then calculated using the formula weight (kg)/height (m2). Also, hand span of both hands was measured from the tip of the thumb to the tip of the small finger with the hand opened as wide as possible. The distance from the distal wrist crease up to the base of the middle finger was taken for palm length and the distal wrist crease to the tip of the middle finger was considered for the measurement of hand length. However, the relationship between HGS and anthropometric parameters was analyzed using Pearson’s product moment coefficient of correlation.Results: The outcome of this study showed that hand and palm length correlated disproportionately and insignificantly (p > 0.05) with both dominant and non-dominant HGS. Also, hand span was found to be a disproportionate correlate of HGS, though such a correlation was only significant (p < 0.05) with dominant HGS. However, BMI and handedness were observed to associate proportionately and significantly (p < 0.05) with HGS.Conclusion: This study therefore concluded that the most important determinants of HGS among Nigerian school children are BMI, handedness and hand span, and thus could be considered as markers of nutritional and health status, as well as physical fitness of these individuals.


Author(s):  
Gillian Barzaga

ABSTRACT Objective: To determine the relationship of the surgeon handedness and operative site laterality on operative duration and hearing improvement in otologic surgery, and to further explore whether this relationship may be related to surgeon experience. Methods:Design: Retrospective CohortSetting: Tertiary Private Teaching HospitalParticipants: Seventy-three (73) patients aged 18 to 65 years old who underwent primary ear surgery under general anesthesia between January 2016 and December 2019 were retrospectively divided into two groups: 39 contralateral and 34 ipsilateral. The operative durations and hearing improvements were compared using independent t-tests, with consideration of surgeon experience in years further stratifying patients. Results: There was no significant difference in operative duration, t(71) = 1.14, p = .26, between the contralateral (M = 281.95 minutes, SD = 71.82) and ipsilateral (M = 261.15, SD = 79.26) groups. This same pattern was more pronounced among surgeons with 10+ years of experience although there was also no significant difference in operative time, t(33) = 1.31, p = .19 for both ipsilateral and contralateral surgeries There was no statistically significant difference, t(36) = -0.72, p = .47, in overall mean hearing gain among patients in the contralateral (M = +2.22 dB, SD = 10.54) and ipsilateral (M = +5.12 dB, SD = 14.26) groups. Although the difference was also not statistically significant, t(16) = -1.94, p = .07 for contralateral (M = 0.00, SD = 5.43) and ipsilateral (M = +7.95 dB, SD = 11.52) procedures performed by surgeons with experience of 10 years or more, a mean hearing gain of +7 dB in the ipsilateral group compared to 0 dB in the contralateral group was notable. Conclusion: This study did not prove that regardless of surgeon experience, right-handed surgeons operating on the right ear and left-handed surgeons operating on the left ear have better ear surgery outcomes of operative duration and hearing improvement compared to right- handed surgeons operating on the left ear and left-handed surgeons operating on the right ear. Future studies on larger samples with more complete data may yet demonstrate this effect.


2020 ◽  
Vol 56 (07) ◽  
pp. 93-95
Author(s):  
Sevinj Mais Nurullayeva ◽  

Human beings perceive of the outside world by listening and reading skills; he also conveys his emotions, thoughts, dreams and impressions to his opponents with his speaking and writing skills. In other words, listening and reading comprehension, speaking and writing is the ability to explain. For this, developing reading, writing skills in primary school children is important. The relationship between this skills should be well understood and attention should be paid to these skills in education and training. Key words: Primary education, researches, reading, writing, relationship of reading and writing


2021 ◽  
Vol 15 (11) ◽  
pp. 3101-3102
Author(s):  
Babar Javaid ◽  
Abrar Ahmed ◽  
Gohar Ali Arshad ◽  
M Shoaib Akhtar ◽  
Shazia Taj ◽  
...  

The study was designed to investigate the relationship of psychological well-being with depression and anxiety among heart patients.1 For this purpose, a sample of 200 patients was taken, including 100 men and 100 women, educated uneducated, employed and unemployed volunteers. The sample was taken from Nishtar Hospital, Combined military hospital and other private hospitals in Multan. The age range from 25 to 60 (mean age 43.085).2,3 Objective: To observe the effect of demographic variables (age, education, gender and source of finance) on psychological well-being and depression, anxiety in heart patients. Methods: 1. Low psychological well-being would be positively correlated with depression and anxiety. 2. Older age (above 50) heart patients would have low sense of psychological well-being as compared to younger age (above 35) heart patients. Results: Different statistical procedures were used to determine the relationship of psychological well-being with depression and anxiety among heart patients. Correlation was computed to see the relationship among variables. It was found that there is negative correlation between psychological well-being with depression and anxiety. Since the p-value in less than α (p-value < 0.01), so we reject null hypothesis Ho, and conclude that low psychological well-being is positively correlated with depression and anxiety. Conclusion: This study also finds out important findings on the role of stresses, feeling of worthlessness in depression and anxiety disorder. It is concluded that psychological well-being, depression and anxiety are not significant correlated with each other. Source of income or job and sex of the heart patients have significant effect on psychological well being. However there is no significant difference between men and women regarding the rate of depression and anxiety. Keywords: P-Value, Correlation, Null Hypothesis , Depression


1962 ◽  
Vol 52 (1) ◽  
pp. 123-131
Author(s):  
D. E. Willis ◽  
James T. Wilson

Abstract A series of controlled high explosive shots were conducted by the Atomic Energy Commission in a salt mine near Winnfield, Louisiana, to investigate seismic decoupling theories. Two recording stations were used by the University of Michigan at various distances between 1.1 and 14.7 kilometers for a majority of these shots. Frequency analyses of the magnetic tape recordings were made and the results are presented showing the relationship of the frequency spectra as a function of charge size, distance from the source, and coupled vs decoupled shots. The smaller decoupled shots detonated in the large spherical cavities were observed to have somewhat higher predominate frequencies than the equivalent size coupled shots. A change in cavity size produced no significant difference in the shape of the spectra of the large decoupled shots.


Author(s):  
D N Logue ◽  
A Lawson ◽  
D J Roberts ◽  
E A Hunter

The importance of lameness in dairy cattle in UK in terms of its economic consequences and welfare considerations is well documented (Russel and others, 1982). While such epidemiological work has identified factors of importance in the aetiology of the various conditions associated with lameness it has been less successful in apportioning their relative importance, particularly for those conditions affecting the hoof. A series of experiments has been conducted at the West of Scotland College over the period 1983 to 1989 mainly investigating the relationship of nutrition and lameness. In one of these Manson and Leaver (1988) found a significant difference in the prevalence of lameness between two groups of cattle fed complete diets containing either 16.1 or 19.8% crude protein. They also found a significant increase in mean locomotion score (LS) and commented that further studies were needed to understand the dietary processes by which the hoof of the cow was predisposed to such problems.The objective of this experiment was to investigate the influence of the type of protein source in the concentrate upon the locomotion of the cows, the incidence and prevalence of lameness and finally on hoof hardness, shape, growth and wear.


1977 ◽  
Vol 55 (10) ◽  
pp. 1108-1113 ◽  
Author(s):  
J. H. Tong ◽  
A. D'Iorio

Particulate catechol-O-methyltransferase (COMT) from rat liver has been solubilized by acetone treatment and partially purified. Results from the present study demonstrate that the solubilized, partially purified enzyme is similar to the cytosol COMT with respect to molecular weight, pH profile, sensitivity toward inhibitors, Mg2+ requirement, and substrate affinities. However, a comparison of the crude particulate COMT and the solubilized enzyme shows that there is a significant difference in their affinity for catechol substrates. This finding suggests that membrane protein and (or) lipid components may play an important role in catecholamine metabolism. The relationship of particulate COMT to [3H]norepinephrine binding was investigated. No correlation between the COMT and [3H]norepinephrine binding activities was observed in vitro.


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