scholarly journals Stability Analysis for a Fractional HIV Infection Model with Nonlinear Incidence

2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Linli Zhang ◽  
Gang Huang ◽  
Anping Liu ◽  
Ruili Fan

We introduce the fractional-order derivatives into an HIV infection model with nonlinear incidence and show that the established model in this paper possesses nonnegative solution, as desired in any population dynamics. We also deal with the stability of the infection-free equilibrium, the immune-absence equilibrium, and the immune-presence equilibrium. Numerical simulations are carried out to illustrate the results.

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Zhiwen Long

Under the assumption that there is a time delay between the time target cells are contacted by the virus particles and the time the contacted cells become actively infected, we investigate the exponential stability of the noninfected equilibrium for a delayed HIV infection model with a nonlinear incidence rate. Compared with the global asymptotic stability analysis based on basic reproduction number, exponential stability analysis reveals the change range of various cells in different time periods.


2013 ◽  
Vol 641-642 ◽  
pp. 808-811
Author(s):  
Xiao Zhang ◽  
Dong Wei Huang ◽  
Yong Feng Guo

In this paper, a class of HIV infection model with delayed immune response has been studied. We analyze the global asymptotic stability of the viral free equilibrium, and the stability and Hopf bifurcation of the infected equilibrium have been studied. Numerical simulations are carried out to explain the results of the analysis, and the change of the immune response of CTLs infects stability of system. These results can explain the complexity of the immune state of AIDs.


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Adnane Boukhouima ◽  
Khalid Hattaf ◽  
Noura Yousfi

We propose a fractional order model in this paper to describe the dynamics of human immunodeficiency virus (HIV) infection. In the model, the infection transmission process is modeled by a specific functional response. First, we show that the model is mathematically and biologically well posed. Second, the local and global stabilities of the equilibria are investigated. Finally, some numerical simulations are presented in order to illustrate our theoretical results.


2021 ◽  
Author(s):  
Resmawan Resmawan ◽  
Agusyarif Rezka Nuha ◽  
Lailany Yahya

This paper discusses the dynamics of COVID-19 transmission by involving quarantine interventions. The model was constructed by involving three classes of infectious causes, namely the exposed human class, asymptotically infected human class, and symptomatic infected human class. Variables were representing quarantine interventions to suppress infection growth were also considered in the model. Furthermore, model analysis is focused on the existence of equilibrium points and numerical simulations to visually showed population dynamics. The constructed model forms the SEAQIR model which has two equilibrium points, namely a disease-free equilibrium point and an endemic equilibrium point. The stability analysis showed that the disease-free equilibrium point was locally asymptotically stable at R0<1 and unstable at R0>1. Numerical simulations showed that increasing interventions in the form of quarantine could contribute to slowing the transmission of COVID-19 so that it is hoped that it can prevent outbreaks in the population.


2016 ◽  
Vol 10 ◽  
pp. 2121-2130
Author(s):  
Mehdi Maziane ◽  
El Mehdi Lotfi ◽  
Marouane Mahrouf ◽  
Khalid Hattaf ◽  
Noura Yousfi

2020 ◽  
Vol 17 (1) ◽  
pp. 109-116
Author(s):  
Lilis Dwi Sapta Aprilyani ◽  
Kasbawati Kasbawati ◽  
Syamsuddin Toaha

HIV is a retrovirus, a virus which has enzymes and can convert genetic material from RNA to DNA. Antiretroviral therapies are the treatment to make the activity of the virus slow. The purpose of this article is to develop a mathematical model of HIV infection by reviewing antiretroviral therapy, analyze the equilibrium point, and determine the effectiveness of antiretroviral therapy. There are two equilibrium points in this HIV infection model, namely infection-free equilibrium and infected equilibrium. Numerical simulations are carried out based on selected parameters showed that infection free equilibrium is reached when the effectiveness of antiretroviral therapy is 0,4 for RT inhibitor and 0,3 for Protease Inhibitor. This means that antiretroviral therapy may change infected conditions to infection free conditions.


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