scholarly journals Influence of Cardiorespiratory Fitness onPPARGmRNA Expression Using Monozygotic Twin Case Control

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Marcos Roberto Queiroga ◽  
Ricardo Augusto Barbieri ◽  
Sandra Aires Ferreira ◽  
André Ducati Luchessi ◽  
Rosario Dominguez Crespo Hirata ◽  
...  
Keyword(s):  
Waist Circumference ◽  
Gas Exchange ◽  
Cardiorespiratory Fitness ◽  
Genetic Background ◽  
Maximal Exercise ◽  
Monozygotic Twin ◽  
Case Control ◽  
Childhood And Adolescence ◽  
Maximal Exercise Test ◽  
Discordant Group

The influence of cardiorespiratory fitness (VO2max) on anthropometric variables andPPARGmRNA expression was investigated. Monozygotic twin pairs aged 11–18 years were grouped into discordant (D) and concordant (C) high and low VO2max groups. VO2max was determined by progressive maximal exercise test on treadmill with gas exchange analysis. Body mass (BM), BMI, waist circumference (WC), triceps (TR), and subscapular (SB) skinfold thicknesses were measured. Twins from the discordant group had differences in VO2max values (D-high =45.9±10.0versus D-low =32.4±10.6 mL·kg−1·min−1,P=0.025), while no differences were found in the concordant group (C-high =42.4±9.2versus C-low =38.8±9.8 mL·kg−1·min−1,P=0.952). In discordant group, VO2max was negatively correlated with TR + SB (r=-0.540,P=0.021) and positively correlated withPPARGexpression in leukocytes (r=0.952,P=0.001). Moreover,PPARGexpression was directly correlated with BM (r=0.714,P=0.047) and height (r=0.762,P=0.028). In concordant twins, VO2max was inversely correlated with BM (r=-0.290,P=0.027), BMI (r=-0.472,P=0.001), WC (r=-0.426,P=0.001), and TR + SB (r=-0.739,P=0.001). Twins D-high had 1.78-fold greaterPPARGexpression when compared with twins D-low (P=0.048). In conclusion, the cardiorespiratory fitness may modulatePPARGexpression in childhood and adolescence, independently of the genetic background.

Chester Step Test in patients with cardiovascular disease: practical applications in a cardiovascular prevention and rehabilitation setting

2020 ◽  
Vol 15 (1) ◽  
pp. 1-10
Author(s):  
Tim Grove
Keyword(s):  
Cardiorespiratory Fitness ◽  
Maximal Exercise ◽  
Low Cost ◽  
Cardiovascular Prevention ◽  
Step Test ◽  
Treadmill Test ◽  
Maximal Exercise Test ◽  
Good Reliability ◽  
Practice Test ◽  
Practical Applications

The Chester Step Test is a low-cost, sub-maximal exercise test, which is commonly used in the assessment of cardiorespiratory fitness in a cardiovascular prevention and rehabilitation setting. This review discusses the practical applications of the Chester Step Test in the context of its validity, reliability and predictability in measuring cardiorespiratory fitness. The Chester Step Test has been compared to the ‘gold standard’ treadmill test for validity. There was a strong correlation (r=0.92) between predicted VO2 values in the test and actual measurements from the treadmill test. In addition, the Chester Step Test has good reliability, which eliminates the need for a practice test. Furthermore, the Chester Step Test can provide valuable information on the patient's exercise tolerance to specific levels of sub-maximal stress, risk stratification, and physical activity/exercise prescription.

Validation of a submaximal versus a maximal exercise test in obese individuals

2015 ◽  
Vol 17 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Anita G.M. Wisén ◽  
Pan Mao ◽  
Leif Christiansen ◽  
Bengt Saltin
Keyword(s):  
Exercise Test ◽  
Maximal Exercise ◽  
Maximal Exercise Test

A COMPARISON OF THE PHYSIOLOGIC RESPONSE OF PATIENTS WITH CHD TO FOUR MAXIMAL EXERCISE TEST PROTOCOLS

1977 ◽  
Vol 9 (1) ◽  
pp. 75 ◽  
Author(s):  
M. D. Glese ◽  
R. J. Corliss ◽  
F. J. Nagle ◽  
T. A. Forman ◽  
Michael Glese
Keyword(s):  
Exercise Test ◽  
Maximal Exercise ◽  
Maximal Exercise Test ◽  
Physiologic Response

Implementing Cardiorespiratory Fitness as a Routine Measure in Health Care Settings

2021 ◽  
Vol 10 (2) ◽  
pp. 62-69
Author(s):  
Jonathan Myers ◽  
Robert Ross
Keyword(s):  
Health Care ◽  
Cardiorespiratory Fitness ◽  
Exercise Test ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Maximal Exercise Test ◽  
Health Care Settings ◽  
Biological Sex ◽  
Clinical Encounters ◽  
Routine Measure

ABSTRACT It is well established that cardiorespiratory fitness (CRF) is inversely associated with numerous morbidities independent of age, biological sex, race or ethnicity, and commonly obtained risk factors. More recent evidence also demonstrates that the addition of CRF to multivariable risk prediction algorithms used to estimate cardiovascular disease risk improves risk stratification. However, it is neither feasible nor appropriate to perform an exercise test to quantify CRF during most routine clinical encounters. A growing number of studies have suggested that CRF can be assessed pragmatically and reasonably accurately without performing a maximal exercise test. The concept that CRF can be substantially improved in response to regular exercise consistent with consensus recommendations underscores the recommendation that CRF should be a routine measure—a vital sign—across health care settings. Herein, we provide a brief, narrative overview of the evidence in support of this recommendation.

scholarly journals Waist circumference thresholds and cardiorespiratory fitness

2019 ◽  
Vol 8 (1) ◽  
pp. 17-22 ◽  
Author(s):  
Sindre M. Dyrstad ◽  
Elisabeth Edvardsen ◽  
Bjørge H. Hansen ◽  
Sigmund A. Anderssen
Keyword(s):  
Waist Circumference ◽  
Cardiorespiratory Fitness

Sport Participation and Metabolic Risk During Adolescent Years: A Structured Equation Model

2018 ◽  
Vol 39 (09) ◽  
pp. 674-681 ◽  
Author(s):  
André Oliveira Werneck ◽  
Danilo da Silva ◽  
Rômulo Fernandes ◽  
Enio Ricardo Vaz Ronque ◽  
Manuel Coelho-e-Silva ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Waist Circumference ◽  
Cardiorespiratory Fitness ◽  
Sport Participation ◽  
Equation Modeling ◽  
Metabolic Risk ◽  
Automatic Instrument ◽  
The Relationship ◽  
Blood Variables

AbstractSports practice during childhood can influence health indicators in later ages through direct and indirect pathways. Thus, this study aimed to test direct and indirect pathways to the association between sports practice in childhood and metabolic risk in adolescence, adopting physical activity, adiposity, and cardiorespiratory fitness at adolescence as potential mediators. This cross-sectional study with retrospective information was conducted with 991 adolescents (579 girls, 412 boys) aged 10 to 16 y. Sports activity was self-reported in childhood (retrospective data) and physical activity evaluated in adolescence through questionnaires. Somatic maturation (Mirwald method), cardiorespiratory fitness (20-m shuttle-run test), body fat (skinfolds), waist circumference, blood pressure (automatic instrument) and blood variables (fasting glucose, HDL cholesterol, and triglycerides) were measured at adolescence. Waist circumference, blood pressure and blood variables composed the metabolic risk score. Structured equation modeling was adopted. In both sexes, the relationship between sports practice at childhood and metabolic risk was fully mediated by habitual physical activity, which is related to the obesity construct and cardiorespiratory fitness. Obesity was associated with metabolic risk in boys (β=0.062; p<0.001) and girls (β=0.047; p<0.001). The relationship between sports practice in childhood and metabolic risk in adolescence was mediated by physical activity, obesity, and cardiorespiratory fitness.

scholarly journals Physical Fitness Is Longitudinally Associated With Academic Performance During Childhood and Adolescence, and Waist Circumference Mediated the Relationship

2018 ◽  
Vol 30 (3) ◽  
pp. 317-325 ◽  
Author(s):  
Rodrigo Antunes Lima ◽  
Lisbeth Runge Larsen ◽  
Anna Bugge ◽  
Lars Bo Andersen
Keyword(s):  
Academic Performance ◽  
Waist Circumference ◽  
Physical Fitness ◽  
Structural Equation ◽  
First Grade ◽  
Composite Score ◽  
Equation Modeling ◽  
Childhood And Adolescence ◽  
Jump Height ◽  
Shuttle Run

Purpose: The current investigation aimed to investigate the longitudinal association between physical fitness and academic performance over 3 years in adolescents. A secondary aim was to determine to what extent waist circumference mediated the association between physical fitness and academic performance. Methods: For the current study, 1020 students from first grade [mean age: 7.87 (0.34) y] to fifth grade [mean age: 11.87 (0.37) y] were monitored annually for 3 years (2010–2013). Physical fitness was assessed using the Andersen test, 5 × 5-m shuttle run, jump height, and grip strength tests and by constructing a composite score combining all 4 fitness tests. Academic performance was assessed by national standardized tests in Danish language and math. Generalized structural equation modeling was used to evaluate the relationships between these variables. Results: The Andersen test (standardized β = 0.15 SD), shuttle run (β = −0.18 SD), jump height (β = 0.10 SD), and the fitness composite score (β = 0.23 SD) were positively associated with academic performance over 3 years. In addition, waist circumference partially mediated the association between physical fitness and academic performance. Conclusion: Thus, physical fitness abilities should be stimulated during childhood and early adolescence because of their positive association with academic performance.

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