scholarly journals GC-FID and NMR Spectroscopic Studies on Gamma Irradiated Walnut Lipids

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Vassilia J. Sinanoglou ◽  
Irini F. Strati ◽  
Katerina Kokkotou ◽  
Dimitra Lantzouraki ◽  
Constantinos Makris ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Irradiation Dose ◽  
Heart Diseases ◽  
Juglans Regia ◽  
Spectroscopic Studies ◽  
Protective Role ◽  
Spectroscopic Techniques ◽  
Coronary Heart Diseases

Walnuts have an excellent fatty acid profile, beneficial for coronary heart diseases. A diet rich in walnuts has shown to decrease the total and LDL cholesterol levels as well as lipoprotein levels. In this study, the effects of different doses ofγ-irradiation and different packaging conditions on proximate composition and fatty acid profile of walnuts (Juglans regiaL.) were investigated merging data from different spectroscopic techniques. Walnuts moisture, ash, fat, and protein content as well as fatty acid profile were evaluated immediately after irradiation. GC-FID results showed that SFA increased and MUFA and PUFA decreased with the increase of irradiation dose. Moreover, MUFA/SFA and PUFA/SFA ratios decreasedP<0.05compared to control samples. Furthermore, NMR spectroscopy was implemented to examine possible discrimination patterns based on irradiation dose and packaging. This approach revealed the role of PUFA decrease with the parallel increase of irradiation dose while indicating the protective role of vacuum and MAP compared to air packaging. In conclusion, at irradiation doses of up to 5 kGy, the walnuts retained the nutritional benefits of its fatty acids, in particular MUFA and PUFA. Concerning the different types of packaging, greater stability in the nuts was observed using MAP packaging.

The role of albumin and PPAR-αin differentiation-dependent change of fatty acid profile during differentiation of mesenchymal stem cells to hepatocyte-like cells

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Shahnaz Esmaeli ◽  
Abdolamir Allameh ◽  
Masoud Soleimani ◽  
Fatemeh Rahbarizadeh ◽  
Mehdi Frouzandeh-Moghadam
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Dependent Change

scholarly journals Relevance of Fatty Acids to Sperm Maturation and Quality

2020 ◽  
Vol 2020 ◽  
pp. 1-14 ◽  
Author(s):  
Giulia Collodel ◽  
Cesare Castellini ◽  
Jetty Chung-Yung Lee ◽  
Cinzia Signorini
Keyword(s):  
Biological Sciences ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Human Sperm ◽  
Dietary Fatty Acids ◽  
Pathological Conditions ◽  
Sperm Membrane ◽  
And Function

Almost 50% of infertility cases are associated with human male infertility. The sperm membrane is a key structure influencing sperm morphology and function in normal and pathological conditions. The fatty acid profile determines the performance not only of sperm motility but also of acrosomal reaction and sperm-oocyte fusion. This review presents available knowledge on the role of fatty acid composition in human sperm and spermatogenesis and discusses the influence of dietary fatty acids on the sperm fatty acid profile. Recent studies in biological sciences and clinical researches in this field are also reported. The topic object of this review has potential application in medicine by identifying potential causes of infertility.

Cadmium and nickel co‐exposure exacerbates genotoxicity and not oxido‐inflammatory stress in liver and kidney of rats: Protective role of omega‐3 fatty acid

2019 ◽  
Vol 35 (2) ◽  
pp. 231-241 ◽  
Author(s):  
Solomon E. Owumi ◽  
Yusuff O. Olayiwola ◽  
Gbenga E. Alao ◽  
Michael A. Gbadegesin ◽  
Oyeronke A. Odunola
Keyword(s):  
Fatty Acid ◽  
Protective Role ◽  
Omega 3 ◽  
Inflammatory Stress ◽  
Omega 3 Fatty Acid ◽  
Liver And Kidney

Protective role of 20-OH ecdysone on lipid profile and tissue fatty acid changes in streptozotocin induced diabetic rats

2013 ◽  
Vol 698 (1-3) ◽  
pp. 489-498 ◽  
Author(s):  
Rajendran Naresh Kumar ◽  
Ramalingam Sundaram ◽  
Palanivelu Shanthi ◽  
Panchanatham Sachdanandam
Keyword(s):  
Fatty Acid ◽  
Lipid Profile ◽  
Protective Role ◽  
Diabetic Rats ◽  
Tissue Fatty Acid

scholarly journals Detailed Spectroscopic Studies in the Aquatic Environment Using Synchrotron Radiation

2019 ◽  
Vol 21 ◽  
pp. 185
Author(s):  
N. Moraitis ◽  
K. Vassalos ◽  
T. J. Mertzimekis ◽  
A. Godelitsas ◽  
P. Gamaletsos ◽  
...  
Keyword(s):  
Aquatic Environment ◽  
Spectroscopic Studies ◽  
Coastal Sediments ◽  
Data Sets ◽  
Spectroscopic Techniques ◽  
Metals And Metalloids ◽  
Synchrotron Facility ◽  
Institute Of Technology ◽  
Karlsruhe Institute

The important role of metals and metalloids in the aquatic environment can be studied by means of Syn- chrotron Radiation (SR)-based X-ray spectroscopic techniques. In the present work, we have performed analyses of data sets (μ–XRF, μ–XANES and μ–EXAFS), for coastal sediments and marine precipitates, obtained at the ANKA Synchrotron Facility in Karlsruhe Institute of Technology (KIT, Germany). Prelim- inary results with regard to the distribution and speciation of toxic (Hg and As) and biocompatible (Fe) metals and metalloids are presented herein. It is therefore demonstrated that Fe is easily precipitated as FeIII oxyhydroxides, most likely related to As, as well as ferrihydrite-type FeIII hydrated oxyhydroxides, whereas Hg is rather accumulated in the form of methyl-containing compounds.

scholarly journals Acyl-CoA thioesterase 1 prevents cardiomyocytes from Doxorubicin-induced ferroptosis via shaping the lipid composition

2020 ◽  
Vol 11 (9) ◽  
Author(s):  
Yunchang Liu ◽  
Liping Zeng ◽  
Yong Yang ◽  
Chen Chen ◽  
Daowen Wang ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Lipid Composition ◽  
Cardiac Injury ◽  
Leading Edge ◽  
Heart Tissue ◽  
Protective Role ◽  
Enzymatic Function

Abstract In this study, we first established the doxorubicin-induced cardiotoxicity (DIC) model with C57BL/6 mice and confirmed cardiac dysfunction with transthoracic echocardiography examination. RNA-sequencing was then performed to explore the potential mechanisms and transcriptional changes in the process. The metabolic pathway, biosynthesis of polyunsaturated fatty acid was significantly altered in DOX-treated murine heart, and Acot1 was one of the leading-edge core genes. We then investigated the role of Acot1 to ferroptosis that was reported recently to be related to DIC. The induction of ferroptosis in the DOX-treated heart was confirmed by transmission electron microscopy, and the inhibition of ferroptosis using Fer-1 effectively prevented the cardiac injury as well as the ultrastructure changes of cardiomyocyte mitochondrial. Both in vitro and in vivo experiments proved the downregulation of Acot1 in DIC, which can be partially prevented with Fer-1 treatment. Overexpression of Acot1 in cell lines showed noteworthy protection to ferroptosis, while the knock-down of Acot1 sensitized cardiomyocytes to ferroptosis by DIC. Finally, the heart tissue of αMHC-Acot1 transgenic mice presented altered free fatty acid composition, indicating that the benefit of Acot1 in the inhibition of ferroptosis lies biochemically and relates to its enzymatic function in lipid metabolism in DIC. The current study highlights the importance of ferroptosis in DIC and points out the potential protective role of Acot1 in the process. The beneficial role of Acot1 may be related to its biochemical function by shaping the lipid composition. In all, Acot1 may become a potential treating target in preventing DIC by anti-ferroptosis.

Protective Role of Italian Juglans regia L. nut Ethanolic Extract in Human Keratinocytes under Oxidative and Inflammatory Stress

2018 ◽  
Vol 18 (11) ◽  
pp. 925-934 ◽  
Author(s):  
Cinzia Calcabrini ◽  
Umberto Mancini ◽  
Roberta De Bellis ◽  
Alessandra Frati ◽  
Anna Rita Mastrogiacomo ◽  
...  
Keyword(s):  
Juglans Regia ◽  
Ethanolic Extract ◽  
Human Keratinocytes ◽  
Protective Role ◽  
Inflammatory Stress
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