scholarly journals Effect of Herbal Prescriptions in Accordance with Pattern Identification in Acute Cerebral Infarction Patients: Based on Fire-Heat Pattern

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
WooSang Jung ◽  
JungMi Park ◽  
SangKwan Moon ◽  
Sangho Hyun
Keyword(s):  
Cerebral Infarction ◽  
Pattern Identification ◽  
Acute Cerebral Infarction ◽  
Baseline Score ◽  
Traditional Korean Medicine ◽  
Clinical Indicators ◽  
Korean Medicine ◽  
Significant Difference ◽  
Heat Pattern

Objectives.This study was conducted to verify the necessity of corresponding prescription to the diagnosed pattern in acute cerebral infarction patients.Methods.We studied cerebral infarction patients hospitalized within 30 days after the ictus. Forty-four clinical indicators, Motricity Index (MI) score, Scandinavian Stroke Scale (SSS) score, and herbal prescriptions were checked twice, two weeks apart. The probability of each pattern was calculated based on the clinical indicators. Changes in MI score, SSS score, and the probability of fire-heat pattern were compared between the pattern-prescription correspondence group and the noncorrespondence group.Results.Increments of MI score and SSS score in the correspondence group were significantly greater than those of the noncorrespondence group (p=0.003,p=0.001) while the baseline score of the two groups showed no significant difference. Probability of fire-heat pattern decreased significantly in the correspondence group (p=0.013) while the noncorrespondence group showed no significant difference after the treatment.Conclusion.Acute cerebral infarction patients who are diagnosed as fire-heat pattern showed better improvement in dysfunctions caused by the disease when they took the pattern corresponding prescriptions. This study provides evidence for the necessity and usefulness of pattern identification in Traditional Korean Medicine.

scholarly journals A Study on the Diagnostic Elements of Cold-Heat Pattern Identification by Korean Medicine Doctors: Association with Objective and Subjective Body Temperature

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Young Joo Park ◽  
Ji-Ho Nam ◽  
Mi Hong Yim ◽  
Honggie Kim ◽  
Jong Yeol Kim
Keyword(s):  
Body Temperature ◽  
Herbal Medicines ◽  
Pattern Identification ◽  
Traditional Korean Medicine ◽  
Korean Medicine ◽  
Significant Difference ◽  
Heat Pattern ◽  
Males And Females ◽  
Gender Groups ◽  
Objectively Measured

Although the Cold-Heat Pattern is the most important diagnostic factor in Traditional Korean Medicine (TKM), its relationship to body temperature and subjective temperature has not been clearly revealed. In this study, based on clinical data from 551 patients, we classified patients treated with herbal medicines into a Cold-prescription group (CG) and a Heat-prescription group (HG), and we compared the ordinary symptoms between the two groups. Subjective body temperature was higher in the HG than in the CG (OR = 1.68, p<0.01) and digestive ability was better in the HG than in the CG (expert’s questionnaire, OR = 1.91, p<0.001). However, objectively measured body temperature did not show any significant difference between the HG and CG in both gender groups (p=0.383 and 0.181 for males and females, resp.). Our study suggests that the subjective body temperature and digestive ability may be the principal diagnostic elements of Cold-Heat Pattern identification by Korean Medicine Doctors. These findings may contribute to the investigation of an objective method to measure the Cold-Heat Pattern.

scholarly journals Sequential butylphthalide therapy combined with dual antiplatelet therapy in the treatment of acute cerebral infarction

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Xuewen Wo ◽  
Jinyan Han ◽  
Jiajia Wang ◽  
Xinmin Wang ◽  
Xiaoying Liu ◽  
...  
Keyword(s):  
Plasma Level ◽  
Cerebral Infarction ◽  
Antiplatelet Therapy ◽  
Adverse Reactions ◽  
Dual Antiplatelet Therapy ◽  
Acute Cerebral Infarction ◽  
Control Group ◽  
Observation Group ◽  
Significant Difference ◽  
Better Than

Objective: To observe the clinical efficacy of sequential butylphthalide therapy combined with dual antiplatelet therapy in the treatment of elderly patients with acute cerebral infarction (ACI). Methods: One hundred and twenty-two elderly patients with ACI who were admitted to the department of neurology of our hospital at May 2016-August 2018 were selected grouped into a control group and an observation group by random number table method, 61 in each group. On the basis of conventional treatment, the patients in the control group were given dual antiplatelet therapy (aspirin enteric-coated tablets + clopidogrel bisulfate tablets), while the patients in the observation group were given sequential butylphthalide therapy on the basis of the control group. The clinical effects of the two groups were compared after four weeks of treatment, and the changes of National Institutes of Health Stroke Scale (NIHSS), ADL score, plasma 3-mercaptopyruvate sulphurtransferase (3-MST) and Amyloid β42 (Aβ42) levels and the occurrence of adverse reactions during treatment were recorded. Results: The clinical efficacy of the observation group was better than that of the control group (P<0.05). There was no significant difference in NIHSS and ADL scores between the two groups before treatment (P>0.05). After treatment, the NIHSS and ADL scores of the observation group were better than those of the control group (P<0.05). There was no significant difference in plasma levels of 3-MST and AB42 between the two groups before treatment (P>0.05). The level of plasma 3-MST in the observation group was higher than that in the control group, and the level of plasma Aβ42 was lower than that in the control group (P<0.05). No serious adverse reactions occurred during the treatment period in both groups. Conclusion: Butylphthalide sequential therapy combined with dual antiplatelet therapy is effective in the treatment of elderly ACI. It can effectively improve the plasma level of 3-MST and decrease the plasma level of Aβ42, which is conducive to improving the living ability and neurological function of patients and has high safety. doi: https://doi.org/10.12669/pjms.36.4.1831 How to cite this:Wo X, Han J, Wang J, Wang X, Liu X, Wang Z. Sequential butylphthalide therapy combined with dual antiplatelet therapy in the treatment of acute cerebral infarction. Pak J Med Sci. 2020;36(4):---------. doi: https://doi.org/10.12669/pjms.36.4.1831 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Developing indicators of pattern identification in patients with stroke using traditional Korean medicine

2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Ju Ah Lee ◽  
Tae-Yong Park ◽  
Jungsup Lee ◽  
Tae-Woong Moon ◽  
Jiae Choi ◽  
...  
Keyword(s):  
Pattern Identification ◽  
Traditional Korean Medicine ◽  
Korean Medicine

scholarly journals Extraction of Clinical Indicators That Are Associated with the Heat/Nonheat and Excess/Deficiency Patterns in Pattern Identifications for Stroke

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Ju Ah Lee ◽  
Mi Mi Ko ◽  
Jungsup Lee ◽  
Byoung-Kab Kang ◽  
Terje Alraek ◽  
...  
Keyword(s):  
Clinical Data ◽  
Large Scale ◽  
Pattern Identification ◽  
Scale Analysis ◽  
Clinical Indicators ◽  
Yin Deficiency ◽  
Large Scale Analysis ◽  
Heat Pattern ◽  
Positive Indicators ◽  
Deficiency Group

The aim of this study is to extract indicators that are associated with the heat/nonheat and excess/deficiency patterns in stroke pattern identification through the large-scale analysis of clinical data. Two experts, who had more than three years of clinical experience with stroke, independently performed the pattern identification. We analyzed indicators of clinical data with two doctors’ concurrent diagnoses on the patient’s pattern identification. To verify heat/nonheat and excess/deficiency patterns, which are the basic elements of pattern identification, we grouped 960 patients diagnosed as the fire-heat pattern, the Yin deficiency pattern, and the Qi deficiency pattern in to two groups, the heat/nonheat group and the excess/deficiency group. We then extracted significant indicators using univariate and multivariate analysis. As a result of the comparison of 65 indicators, we were able to extract 10 indicators for the heat pattern, 6 for the nonheat pattern, 9 for the excess pattern, and 10 for the deficiency pattern. Extracted indicators in this study can be used for pattern identification in the context of stroke. These are positive indicators from large-scale clinical studies and are greatly expected to be crucial discriminant indicators in individual pattern identification henceforth.

scholarly journals Effects of care transitions intervention mode on the benefit-finding in caregivers for patients with acute cerebral infarction

2021 ◽  
Keyword(s):  
Quality Of Life ◽  
Cerebral Infarction ◽  
Care Transitions ◽  
Family Relationship ◽  
Intervention Group ◽  
Acute Cerebral Infarction ◽  
Benefit Finding ◽  
Control Group ◽  
Significant Difference

To explore the effect of care transitions intervention (CTI) on the sense of benefit-finding of caregivers for patients with acute cerebral infarction (ACI). Ninety caregivers for patients with ACI were divided into two groups according to the random number table method (n = 45 in each group). The control group was given regular health guidance, and the intervention group was given care transitions intervention on the basis of the guidance used in the control group. The changes in the sense of benefit-finding and quality of life between the two groups were compared before and after the intervention. There was no statistically significant difference in caregivers between the two groups in gender, age, educational level, occupational status, gender and age of the patients, activities of daily living (ADL) scores before discharge, and the relationships between the caregiver and the patient. Before CTI, there was no statistically significant difference in the caregivers’ sense of benefit-finding (including sense of benefit, family relationship, personal growth, social relationship and healthy behavior) and quality of life (including benefit-finding of care, stress of care, choice of care, support to care and money issue) between the two groups. While after CTI, the scores of each dimension of the caregivers’ sense of benefit-finding and quality of life in the intervention group were significantly higher than those in the control group (p < 0.05). The CTI can help improve the sense of benefit-finding and quality of life of caregivers for patients with ACI.

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