scholarly journals Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Andrew C. Harbin ◽  
Andrew Chen ◽  
Siddharth Bhattacharyya ◽  
Jasvir S. Khurana ◽  
Joshua R. Kaplan ◽  
...  

Oncocytic tumors, composed of eosinophilic, mitochondria-rich cells, can occur in several locations throughout the body. These tumors can occur in the adrenal cortex and are rarely malignant. We report a case of a patient presenting with an incidental adrenal mass which was later diagnosed as a oncocytic adrenocortical neoplasm (OAN). The patient is a 53-year-old man found to have a 7.2 cm right adrenal mass, incidentally found by computed tomography (CT). After metabolic workup was negative, a right robotic adrenalectomy (RA) was performed. Pathologic analysis revealed clusters of large cells with abundant eosinophilic and granular cytoplasm, consistent with OAN. This pathology is rare, with only about 150 cases described in the literature. It occurs in females 2.5 times more frequently and more commonly on the left side. Diagnosis is usually made by imaging criteria, typically with CT or magnetic resonance imaging (MRI). Treatment is generally surgical, since OAN can be malignant in some cases. Differentiation between benign and malignant OAN is done based on the Lin-Weiss-Bisceglia criteria and can be difficult. If malignancy is diagnosed, recurrence is common and close surveillance should be performed.

Foot & Ankle ◽  
1987 ◽  
Vol 8 (3) ◽  
pp. 144-147 ◽  
Author(s):  
Ian J. Alexander ◽  
Kenneth A. Johnson ◽  
Thomas H. Berquist

Magnetic resonance imaging (MRI), a useful technique of studying soft tissues of the body, can be very effective in assessing the integrity of tendons. Usually a patient with a complete tear of the posterior tibial tendon has characteristic physical findings. In the patient presented, MRI demonstrated a complete disruption of the posterior tibial tendon, despite the absence of the commonly associated clinical findings. In view of the difficulties encountered with attempted tenography of the completely torn posterior tibial tendon, MRI provides a sensitive alternative diagnostic technique.


Author(s):  
Gamze Akkus ◽  
Ferhat Piskin ◽  
Barış Karagun ◽  
Murat Sert ◽  
Mehtap Evran ◽  
...  

Background: Diagnostic imaging techniques including magnetic resonance imaging (MRI) should also perform on all patients with incidentalomas. However, there is a limited study whether the quantitative measurements (signal intensity index, adrenal to spleen ratio) in MRI could predict the functional status of adrenal adenomas. Material-Method: Between 2015-2020; 404 patients (265 females, 139 males) with adrenal mass who were referred to the university hospital for further investigation were included. After detailed diagnostic hormonal evaluation, all patients underwent MRI 1.5 T device (Signa, GE Medical Systems; Milwaukee, USA). The signal intensities of the adrenal lesions on T2W images were qualitatively evaluated and noted as homogenous or heterogeneous in comparison with the liver signal intensity (SI). A chemical-shift SI index and chemical shift adrenal-to-spleen SI ratio were also calculated. Results: While 331(81.9%) of the patients had nonfunctional adrenal mass, the rest of them (n=73, 18.1%) were patients with functional (autonomous cortisol secretion-ACS, cushing syndrome-CS, pheochromocytoma, primary hyperaldosteronism-PA) adrenal masses. In phase vs phase values of patients with NFAI, Pheo(n=17), ACS (n=30), CS (n=11), and PA (n=15) were 474.04±126.7 vs 226.6±132.4, 495.3±182.8 vs 282.17±189.1, 445.2±134.8 vs 203.3±76.2, 506.8±126.5 vs 212.2±73.6 and 496.2±147.5 vs 246.6±102.1, respectively. Mean signal intensity index (SII) and adrenal to spleen ratio (ASR) of all groups (NFAI, Pheo, ACS, CS, PA) were 52.0±24.8 and 0.51, 44.9±22.5 and 0.55, 49.5±24.5 and 0.53, 56.2±16.4 and 0.43, 47.6±25.1 and 0.54, respectively. Based the current accepted measurements in the case of ASR and SII, all lesions were similar and shown as fat rich adenomas (p*= 0.552, p** = 0.45). Conclusion: The quantitative assessment (SII, ASR) of intracellular lipids in an incidentally discovered adrenal tumour could only help distinguish adrenal masses in case of adenomas or non-adenomas As initial diagnostic evaluation, clinical and laboratory assessment ,to distinguish hormone secretion, should be taken in all patients with adrenal incidentalomas.


2008 ◽  
Vol 36 (2) ◽  
pp. 315-319 ◽  
Author(s):  
Charles A. Nelson

Magnetic resonance imaging (MRI) is a noninvasive imaging tool that utilizes a strong magnetic field and radio frequency waves to visualize in great detail organs, soft tissue, and bone. Unlike conventional x-rays (including computed tomography [CT]), there is no exposure to ionizing radiation and at most field strengths (generally below 7 Tesla) the procedure is considered safe for nearly every age group. Because it is non-invasive (i.e., does not break the skin or harm the body) and possesses excellent spatial resolution (down to millimeters), the use of MRI as a research tool has increased exponentially over the past decade. Uses have ranged from add-ons to a clinical study (e.g., after scanning a child who has fallen from a bicycle, the radiologist might do an extra sequence to explore ways of obtaining higher resolution images) to studies of brain development in typically developing children. In addition, a major effort has been made in recent years to use MRI to study brain function (so-called “functional MRI” [fMRI]). Because the clinical utility of fMRI has not yet been realized, fMRI is still considered highly exploratory, and we cannot yet identify incidental findings of a functional (as opposed to structural) nature.


2003 ◽  
Vol 75 (9) ◽  
pp. 1343-1348 ◽  
Author(s):  
Yoshinori Yamamoto

The evaluation of the Gd-carborane DTPA complex as a magnetic resonance imaging (MRI) and boron carrier agent was carried out in vivo. The MRI revealed that the Gd-carborane DTPA was metabolized slower in the body in comparison with Gd-DTPA.


2008 ◽  
Vol 24 (04) ◽  
pp. 452-458 ◽  
Author(s):  
Mohammad Palesh ◽  
Sten Fredrikson ◽  
Hamidreza Jamshidi ◽  
Goran Tomson ◽  
Max Petzold

Objectives:Analysis of and understanding the utilization patterns of diagnostic imaging technologies is important for planning health systems especially in middle- and low-income countries. Almost all published studies have been focused on utilization trends or utilization rates of magnetic resonance imaging (MRI) over time and little has been published about utilization patterns of MRI. This study aims to identify and describe the utilization pattern of MRI in Iran.Methods:Data was collected from referrals and MRI reports of the population covered by one of the largest insurance organizations (Social Security Organization [SSO]) with more than 27 million beneficiaries in the Country. We focused on patients who had undergone an MRI examination during 1 month (October 13 to November 12), 2005. The data collected consisted of 1,656 referrals for MR imaging and 1,547 MRI reports.Results:No clear association was found between the number of referrals per 100,000 population and the number of MRI machines per 100,000 population (r = 0.30;p= .13). Neurosurgeons, orthopedists, and neurologists contributed to more than 88 percent of MRI utilization. The Spinal column (55 percent), brain (25.5 percent), and knee (11.0 percent) were the most common parts of the body scanned by MRI.Conclusions:Having identified some of the most frequent users of MRI technology, any plan for modifying or improving MRI use should focus mainly on these specialties. International evidence on using the technology for examining brain and spine indicate that MRI is mainly used in diagnosing the central nervous system (CNS) diseases.


2008 ◽  
Vol 65 (7) ◽  
pp. 1245-1249 ◽  
Author(s):  
Bonnie L. Rogers ◽  
Christopher G. Lowe ◽  
Esteban Fernández-Juricic ◽  
Lawrence R. Frank

The physical consequences of barotrauma on the economically important rockfish ( Sebastes ) were evaluated with a novel method using T2-weighted magnetic resonance imaging (MRI) in combination with image segmentation and analysis. For this pilot study, two fishes were captured on hook-and-line from 100 m, euthanized, and scanned in a 3 Tesla human MRI scanner. Analyses were made on each fish, one exhibiting swim bladder overinflation and exophthalmia and the other showing low to moderate swim bladder overinflation. Air space volumes in the body were quantified using image segmentation techniques that allow definition of individual anatomical regions in the three-dimensional MRIs. The individual exhibiting the most severe signs of barotrauma revealed the first observation of a gas-filled orbital space behind the eyes, which was not observable by gross dissection. Severe exophthalmia resulted in extreme stretching of the optic nerves, which was clearly validated with dissections and not seen in the other individual. Expanding gas from swim bladder overinflation must leak from the swim bladder, rupture the peritoneum, and enter the cranium. This MRI method of evaluating rockfish following rapid decompression is useful for quantifying the magnitude of internal barotrauma associated with decompression and complementing studies on the effects of capture and discard mortality of rockfishes.


Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2378
Author(s):  
Eri Onozawa ◽  
Daigo Azakami ◽  
Seri Seki ◽  
Yuji Hamamoto ◽  
Katsumi Ishioka

Dogs and cats under general anesthesia may develop hypothermia. When performing a magnetic resonance imaging (MRI) examination, it is not possible to place a magnetic material in the MRI room, and MRI equipment requires a low room temperature. This study investigated the effectiveness of a heat insulating device that prevented hypothermia during MRI examinations in dogs and cats. The animals that underwent MRI examinations under general anesthesia were divided into control groups (no covering) and heat insulating groups (wearing bubble wrap and down cloth blankets), and their body temperatures were measured before and after the MRI examinations. The changes in body temperatures were as follows: control dogs (n = 17), median of −1.0 (from −2.5 to 0.3) °C; heat insulated dogs (n = 7), −0.3 (from −0.8 to 0.2) °C; control cats (n = 14), −1.85 (from −2.7 to −0.6) °C; and heat insulated cats (n = 12), −0.8 (from −1.5 to −0.1) °C. These results revealed that the bubble wrap and down cloth blanket significantly prevented hypothermia and heat loss from the body surface during MRI examinations of dogs and cats.


Author(s):  
Pratishtha Kushwaha ◽  
Pratima Chauhan

Abstract: Iron oxide nanoparticles by the help of legitimate surface science have been broadly utilized tentatively in many living organism applications, for example magnetic resonance imaging (MRI), drug delivery, Repair of tissue, immunobiology, hyperthermia, detoxification of natural liquids, differentiate improvement between low contrast and high contrast tissues, and in cell partition and so on. What's more, these applications need exceptional nontoxic and biocompatible surface covering of the attractive particles to permit a targetable conveyance with molecular restriction in a particular territory. The general size of the colloid can be estimated ordinarily of surface covering and their resulting spatial course of action adjacent to the nanoparticles, it additionally assumes a critical job in bio-kinetics and bio-distribution of nanoparticles in the body. The kinds of surface coatings, for this sort of nanoparticles rely upon the kind of application and ought to be picked by remembering a specific application, regardless of whether it is gone for aggravation reaction or anti-cancer agents. In this paper, we examine the manufactured science, liquid adjustment and surface change of iron oxide nanoparticles, just as their utilization for biomedical applications


2020 ◽  
pp. 1-7
Author(s):  
Blaurock-Busch Eleonore

Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of Magnetic Resonance Imaging (MRI) or Magnetic Resonance Angiography (MRA). FDA alerts concerning potential side effects increased patient and medical concerns. More recent FDA information indicate that ionic gadolinium is released from some GBCAs, potentially causing gadolinium toxicity. We checked if gadolinium is excreted renally without intervention after previous administration of GBCAs, and if chelating agents are effective in removing gadolinium that may have remained in the body after GBCA administration. Through the evaluation of our internal database and the studies of others, we concluded that no clear consensus exists at this time. While the DTPAs may be the choice of chelators for the removal of gadolinium from the human body, further studies are needed to prove this. It seems clear, however, that microcyclic GBCAs provide a lesser risk of causing gadolinium retention and gadolinium toxicity symptoms.


1987 ◽  
Vol 19 (3-4) ◽  
pp. 221-237 ◽  
Author(s):  
A. R. Margulis ◽  
H. Hricak ◽  
L. Crooks

In the very short time since magnetic resonance imaging (MRI) was born it has gained surprisingly rapid and enthusiastic acceptance and has speedily proliferated, particularly in the United States and Western Europe. Magnetic resonance imaging (MRI) has successfully challenged computed tomography (CT) in all areas of the body where respiratory motion does not degrade the image (Steinberg, 1986). Newer techniques using a multiplicity of approaches are starting to close the gap between CT and MRI, even in the upper abdomen where the effects of respiratory motion are most pronounced. Although MR is already widely clinically applied and is an accepted everyday diagnostic modality in most large medical centres in the United States, it is not a mature modality. It is rapidly evolving, with whole new areas opening to investigation which will vastly broaden its applications.


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