scholarly journals Hemostatic Parameters according to Renal Function and Time after Transplantation in Brazilian Renal Transplanted Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Ana Paula Lucas Mota ◽  
Patrícia Nessralla Alpoim ◽  
Roberta Carvalho de Figueiredo ◽  
Ana Cristina Simões e Silva ◽  
Karina Braga Gomes ◽  
...  
Keyword(s):  
Renal Function ◽  
Glomerular Filtration ◽  
Plasma Levels ◽  
Cross Sectional ◽  
Hemostatic System ◽  
Stage Renal Disease ◽  
End Stage ◽  
Von Willebrand ◽  
Willebrand Factor

Kidney transplantation is the key for patients with end-stage renal disease, improving quality of life and longer survival. However, kidney transplant triggers an intense inflammatory response and alters the hemostatic system, but the pathophysiological mechanisms of these changes are not completely understood. The aim of this cross-sectional cohort study was to investigate hemostatic biomarkers in Brazilian renal transplanted patients according to renal function and time after transplantation. A total of 159 renal transplanted patients were enrolled and D-Dimer (D-Di), Thrombomodulin (TM), von Willebrand Factor (VWF), and ADAMTS13 plasma levels were assessed by ELISA. An increase of D-Di was observed in patients with higher levels of creatinine. ADAMTS13 levels were associated with creatinine plasma levels and D-Di levels with Glomerular Filtration Rate. These results suggested that D-Di and ADAMTS13 can be promising markers to estimate renal function. ADAMTS13 should be investigated throughout the posttransplant time to clarify the participation of this enzyme in glomerular filtration and acceptance or rejection of the graft in Brazilian transplanted patients.

Effects of Dietary Manipulation with Fish Oil on Platelet Receptors for von Willebrand Factor and Fibrinogen in Patients with End-Stage Renal Disease

Nephron ◽  
1995 ◽  
Vol 69 (2) ◽  
pp. 170-170 ◽  
Author(s):  
Mario Liani ◽  
Ettore Tresca ◽  
Giuseppe Nubile ◽  
Filippo Salvati ◽  
Pierre Trolliet ◽  
...  
Keyword(s):  
Renal Disease ◽  
Fish Oil ◽  
Von Willebrand Factor ◽  
End Stage Renal Disease ◽  
Dietary Manipulation ◽  
Platelet Receptors ◽  
Stage Renal Disease ◽  
End Stage ◽  
Von Willebrand ◽  
Willebrand Factor

Replacement Therapy and Its Impact on Quality of Life in Patients with End-Stage Kidney Disease

2019 ◽  
Vol 27 (1) ◽  
pp. 17
Author(s):  
Fernando Martínez Gutiérrez ◽  
Ivonne Analí Roy García ◽  
José Luis Torres Rodríguez
Keyword(s):  
Quality Of Life ◽  
Renal Disease ◽  
Replacement Therapy ◽  
End Stage Renal Disease ◽  
Self Assessment ◽  
Cross Sectional ◽  
Assessment Index ◽  
Stage Renal Disease ◽  
End Stage

<p><strong>Objective:</strong> to assess the quality of life (QoL) score according to the type of renal replacement therapy (rrt) in patients with end-stage renal disease (esrd). <strong>Methods:</strong> cross-sectional, analytical study. Patients with esrd, on peritoneal dialysis (pd) or hemodialysis (hd), older than 18 years, without disease exacerbation, assigned to the Regional General Hospital No. 1 of Mexico City, were included. The study was carried out from December 2018 to March 2019. QoL was measured with the eq-5D index and the visual analogue scale to obtain a health self-assessment index; clinical and sociodemographic variables were obtained from the medical record and through interrogation. Results: a total of 406 participants, 203 patients on hemodialysis and 203 on pd, were included. A mean eq-5D index score of 0.46 ± 0.18 was found for pd versus 0.29 ± 0.22 for hd (p &lt; 0.001). The self-assessment index showed no difference between both groups. The quality of life indicators that were most affected in patients treated with hd were pain and anxiety or depression. <strong>Conclusion:</strong> in patients with end-stage renal disease, hd is associated with lower quality of life.</p>

The association between hope and quality of life in haemodialysis patients

2020 ◽  
Vol 29 (21) ◽  
pp. 1260-1265
Author(s):  
Ali Alshraifeen ◽  
Sami Al-Rawashdeh ◽  
Kaye Herth ◽  
Karimeh Alnuaimi ◽  
Fatmeh Alzoubi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Healthcare Providers ◽  
World Health ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Cross Sectional Design ◽  
Health Organization ◽  
Stage Renal Disease ◽  
End Stage

Background: Hope is important for patients with end-stage renal disease receiving haemodialysis (HD) and hope is associated with quality of life (QoL). Studies examining hope among the HD population are limited and, as far as the authors know, have not been undertaken in Jordan. Aims: To examine levels of hope and QoL and to examine the association between hope and QoL in HD patients in Jordan. Methods: A cross-sectional design was used. A convenience sample of 202 patients from six different dialysis centres was recruited. The World Health Organization QOL-BREF and the Herth Hope Index were used. Findings: Moderate levels of hope (M=32.3±4.1) were reported. Respondents reported low mean scores for the physical domain of QoL (M=48.3±21.1) but not for the psychological and social relationship domains. Higher hope scores were associated with better QoL. Conclusion: The findings suggest a positive relationship between the level of hope and QoL in people receiving HD. Encouraging hope while caring for HD patients in clinical settings may improve their QoL. Understanding the relationship between hope and QoL may help healthcare providers to improve the quality of care for patients and their families.

scholarly journals Religious coping methods predict depression and quality of life among end-stage renal disease patients undergoing hemodialysis: a cross-sectional study

2017 ◽  
Vol 18 (1) ◽  
Author(s):  
Paulo Roberto Santos ◽  
José Roberto Frota Gomes Capote Júnior ◽  
José Renan Miranda Cavalcante Filho ◽  
Ticianne Pinto Ferreira ◽  
José Nilson Gadelha dos Santos Filho ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Religious Coping ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Coping Methods ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals The Effect of Clinical and Demographic Factors on Quality of Life in End-Stage Renal Disease. A Multicenter Cross-Sectional Study

2020 ◽  
Vol 4 (1) ◽  
pp. 1-9
Author(s):  
Evangelos C. Fradelos
Keyword(s):  
Quality Of Life ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Area Of Interest ◽  
Stage Renal Disease ◽  
End Stage

The aim of this study was to assess the quality of life (QoL) in end-stage renal disease (ESRD) patients undergoing hemodialysis and to examine the clinical and demographic attributes associated with it.This is a multicenter, cross-sectional study, conducted in 2018, in which 367 patients with ESRD undergoing hemodialysis were recruited. Data were collected through a two-part anon-ymous, self-completed questionnaire. The first part contained questions regarding demographic, social, and clinical information, and the Greek version of Missoula–Vitas Quality of Life Index-15 (MVQoL-15) scale was used to assess QoL. Descriptive and inferential statistical methods were applied. All reported p-values were two-tailed, and the statistical significance level was set at 0.05. Of the study participants, 62.1% were male, with a mean age of 61.80 ±15.11. Of the participants, 67.3% were living in urban areas and 59.1% were married. The majority of the Hemodialysis (HD) patients evaluated possessively all the domains of MVQoL except the wellbeing Domain. QoL was found to be influenced, among others, by age (0.001), occupation (0.002), education (0.003), and additional health problems (<0.001). The role of patient characteristics in QoL is an area of interest, and early and proper intervention is important to enhance QoL.

Protein Adsorption on EX VIVO Catheters and Polymers Exposed to Peritoneal Dialysis Effluent

2004 ◽  
Vol 24 (3) ◽  
pp. 264-273 ◽  
Author(s):  
Naoko Yanagisawa ◽  
Dai-Qing Li ◽  
Åsa Ljungh
Keyword(s):  
Peritoneal Dialysis ◽  
Ex Vivo ◽  
Adhesion Sites ◽  
Polyethylene Tubing ◽  
Stage Renal Disease ◽  
End Stage ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Peritoneal Dialysis Effluent

Background Deposition of proteins on surfaces of medical devices has been recognized to putatively relate to the process of regulation of biomaterial-associated complications by attachment of fibrin clots, eukaryotic cells, and microbes. The molecules adsorb to a varying extent, depending not only on the physicochemical properties of the biomaterial, but also on the composition of the host fluid. Objective Adsorption of proteins on catheters exposed both ex vivo and in vitro to dialysate of patients on peritoneal dialysis (PD) was studied. Methods Peritoneal dialysis effluent was collected from 5 patients with end-stage renal disease on continuous ambulatory PD. Tenckhoff catheters were obtained from 16 patients. Deposition of proteins on excised Tenckhoff catheters and tubing of different materials exposed to PD effluent in vitro was studied using 125iodine-labeled antibodies. Adhesion of Staphylococcus aureus and Staphylococcus epidermidis strains was quantified on tubing exposed to PD effluent in vitro. Results The presence of albumin, transferrin, immunoglobulin G, fibrinogen, fibronectin, von Willebrand factor, vitronectin, and thrombospondin was determined at various concentrations in PD effluent. All proteins analyzed were detected on PD catheters removed from patients. The extent of protein deposition on Tenckhoff catheters exposed to PD effluent, in vitro, rapidly reached a plateau and remained constant, as it did on polyvinyl chloride and polyethylene tubing. Adhesion of staphylococci was enhanced on Tenckhoff catheters exposed to PD effluent compared to unused PD solution. Conclusions The data identify surface exposed proteins that may serve as adhesion sites for microbes on peritoneal catheters indwelled in patients undergoing PD.

scholarly journals Circulating active von Willebrand factor levels are increased in chronic kidney disease and end-stage renal disease

2019 ◽  
Vol 13 (1) ◽  
pp. 72-74 ◽  
Author(s):  
Lisa N van der Vorm ◽  
Ruben Visser ◽  
Dana Huskens ◽  
Alicia Veninga ◽  
Denise L Adams ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Disease ◽  
Von Willebrand Factor ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage ◽  
Von Willebrand ◽  
Willebrand Factor

scholarly journals Quality of life in Palestinian patients with end-stage renal disease receiving treatment by haemodialysis: a cross-sectional study

The Lancet ◽  
2018 ◽  
Vol 391 ◽  
pp. S32
Author(s):  
Sa'ed H Zyoud ◽  
Dala N Daraghmeh ◽  
Diana O Mezyed ◽  
Razan L Khdeir ◽  
Mayas N Sawafta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Stage Renal Disease ◽  
End Stage
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