scholarly journals Disseminated Herpes Simplex Virus with Fulminant Hepatitis

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Bassam H. Rimawi ◽  
Joseph Meserve ◽  
Ramzy H. Rimawi ◽  
Zaw Min ◽  
John W. Gnann

Disseminated herpes simplex virus (HSV) is a rare cause of acute fulminant liver failure. We hereby present a case series of three patients with acute disseminated HSV with necrotizing hepatitis successfully treated with a week course of acyclovir. Early empiric administration of acyclovir therapy while awaiting confirmatory tests is critical in this potentially lethal disease.

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Ashwinee Natu ◽  
Guiseppe Iuppa ◽  
Clifford D. Packer

Objective. To compare three cases of Herpes simplex virus (HSV) hepatitis to increase early diagnosis of the disease. Case  1. A 23-year-old man with Crohn’s disease and oral HSV. HSV hepatitis was diagnosed clinically and he improved with acyclovir. Case  2. An 18-year-old G1P0 woman with transaminitis. Despite early empiric acyclovir therapy, she died due to fulminant liver failure. Case  3. A 65-year-old woman who developed transaminitis after liver transplant. Diagnosis was confirmed by biopsy and she had resolution of acute liver failure with acyclovir. Conclusion. It is imperative that clinicians be aware of patients at high risk for developing HSV hepatitis to increase timely diagnosis and prevent morbidity and fatality.


1995 ◽  
Vol 14 (3) ◽  
pp. 242-243 ◽  
Author(s):  
David S. Greenes ◽  
David Rowitch ◽  
Grace M. Thorne ◽  
Antonio Perez-Atayde ◽  
Frank S. Lee ◽  
...  

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