scholarly journals Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Du Ri Seo ◽  
Seung Joo Ha
Keyword(s):  
Fixed Combination ◽  
Open Angle Glaucoma ◽  
Pulse Amplitude ◽  
Normal Tension Glaucoma ◽  
Treated Group ◽  
Applanation Tonometry ◽  
Dynamic Contour Tonometry ◽  
Ocular Pulse Amplitude ◽  
Ocular Pulse ◽  
Preservative Free

Purpose. To compare the ocular pulse amplitude (OPA) lowering effects of preservative-free tafluprost and dorzolamide-timolol fixed combination (DTFC) using dynamic contour tonometry.Methods. In total, 66 eyes of 66 patients with normal tension glaucoma (NTG) (n=34) or primary open angle glaucoma (POAG) (n=32) were included. Patients were divided into two groups: the preservative-free tafluprost-treated group (n=33) and the preservative-free DTFC-treated group (n=33). Intraocular pressure (IOP) was measured using Goldmann applanation tonometry (GAT). OPA was measured using dynamic contour tonometry; corrected OPA (cOPA) was calculated at baseline and at 1 week and 1, 3, and 6 months after treatment.Results. After 6 months of treatment, tafluprost significantly reduced IOP (P<0.001). The OPA lowering effects differed significantly between the two treatment groups (P=0.003). The cOPA-lowering effect of tafluprost (1.09 mmHg) was significantly greater than that of DTFC (0.36 mmHg) after 6 months of treatment (P=0.01).Conclusions. Tafluprost and DTFC glaucoma treatments provided marked OPA and IOP lowering effects. Tafluprost had a greater effect than DTFC; thus, this drug is recommended for patients at risk of glaucoma progression, due to the high OPA caused by large fluctuations in IOP.

scholarly journals Travoprost- and Tafluprost-induced Changes in Intraocular Pressure and Ocular Pulse Amplitude

2021 ◽  
Vol 62 (9) ◽  
pp. 1235-1242
Author(s):  
Gyeong Min Lee ◽  
Seung Joo Ha
Keyword(s):  
Intraocular Pressure ◽  
Open Angle Glaucoma ◽  
Pulse Amplitude ◽  
Applanation Tonometry ◽  
Dynamic Contour Tonometry ◽  
Long Term Effects ◽  
Ocular Pulse Amplitude ◽  
Induced Changes ◽  
First Time ◽  
Ocular Pulse

Purpose: To compare the intraocular pressure reduction and changes in ocular pulse amplitude of travoprost 0.003% and tafluprost 0.0015%. Methods: We assessed patients who were diagnosed with open-angle glaucoma from January 2017 to July 2019 for the first time at our hospital. Forty-two eyes were assigned to the travoprost group (23 patients) and 26 eyes were assigned to the tafluprost group (14 patients). Changes in intraocular pressure were measured by Goldmann applanation tonometry (GAT), and corrected ocular pulse amplitude (cOPA) was measured using dynamic contour tonometry. Changes in these parameters were observed and compared for 1 year. Results: No significant differences were observed between the GAT measurements and the cOPA of patients treated with travoprost and tafluprost for 1 year (p = 0.512, p = 0.105). The change in initial intraocular pressure on GAT observed after 1 week was -5.32 ± 2.63 mmHg for travoprost and -3.79 ± 3.19 mmHg for tafluprost (p = 0.0457). The initial change in cOPA was +0.04 ± 0.9 mmHg in the travoprost group and -0.76 ± 0.97 mmHg in the tafluprost group (p = 0.0028). Conclusions: Travoprost and tafluprost reached the targeted intraocular pressure with no difference in the long-term effects of reduced intraocular pressure. However, travoprost was initially better at lowering intraocular pressure faster, and tafluprost had a greater effect on lowering OPA. Prostaglandin analogs can be selected individually by considering the aforementioned factors.

Intraocular Pressure and Ocular Pulse Amplitude Comparisons in Different Types of Glaucoma Using Dynamic Contour Tonometry

2006 ◽  
Vol 31 (10) ◽  
pp. 851-862 ◽  
Author(s):  
Omar S. Punjabi ◽  
Hoai-Ky V. Ho ◽  
Christoph Kniestedt ◽  
Alan G. Bostrom ◽  
Robert L. Stamper ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Pulse Amplitude ◽  
Dynamic Contour Tonometry ◽  
Ocular Pulse Amplitude ◽  
Different Types ◽  
Ocular Pulse

The Clinical Utility of Dynamic Contour Tonometry and Ocular Pulse Amplitude

2007 ◽  
Vol 16 (8) ◽  
pp. 700-703 ◽  
Author(s):  
Jennifer S. Weizer ◽  
Sanjay Asrani ◽  
Sandra S. Stinnett ◽  
Leon W. Herndon
Keyword(s):  
Clinical Utility ◽  
Pulse Amplitude ◽  
Dynamic Contour Tonometry ◽  
Ocular Pulse Amplitude ◽  
Ocular Pulse

Lower ocular pulse amplitude with dynamic contour tonometry is associated with biopsy-proven giant cell arteritis

2018 ◽  
Vol 53 (3) ◽  
pp. 215-221 ◽  
Author(s):  
Edsel Ing ◽  
Christian Pagnoux ◽  
Felix Tyndel ◽  
Arun Sundaram ◽  
Seymour Hershenfeld ◽  
...  
Keyword(s):  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Pulse Amplitude ◽  
Dynamic Contour Tonometry ◽  
Ocular Pulse Amplitude ◽  
Ocular Pulse

Diurnal variation of ocular pulse amplitude in primary open angle glaucoma patients

2010 ◽  
Vol 88 ◽  
pp. 0-0
Author(s):  
LA PINTO ◽  
P LEITãO ◽  
J FERREIRA ◽  
I DOMINGUES ◽  
E VANDEWALLE ◽  
...  
Keyword(s):  
Diurnal Variation ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Pulse Amplitude ◽  
Open Angle ◽  
Ocular Pulse Amplitude ◽  
Ocular Pulse
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